Independent Labs, Institutes, and Centers (Dean of Research)
Showing 51-99 of 99 Results
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Lambertus Hesselink
Professor of Electrical Engineering and, by courtesy of Applied Physics
BioHesselink's research encompasses nano-photonics, ultra high density optical data storage, nonlinear optics, optical super-resolution, materials science, three-dimensional image processing and graphics, and Internet technologies.
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Shaul Hestrin, PhD
Professor of Comparative Medicine
Current Research and Scholarly InterestsThe main interest of my lab is to understand how the properties of neocortical neurons, the circuits they form and the inputs they receive give rise to neuronal activity and behavior. Our approach includes behavioral studies, two-photon calcium imaging, in vivo whole cell recording in behaving animals and optogenetic methods to activate or to silence the activity of cortical neurons.
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Brian Hie
Assistant Professor of Chemical Engineering
BioI am an Assistant Professor of Chemical Engineering and Data Science at Stanford University, and an Innovation Investigator at Arc Institute. I supervise the Laboratory of Evolutionary Design, where we conduct research at the intersection of biology and machine learning.
I was previously a Stanford Science Fellow in the Stanford University School of Medicine and a Visiting Researcher at Meta AI. I completed my Ph.D. at MIT CSAIL and was an undergraduate at Stanford University. I have also previously worked at Google X, Illumina, and Salesforce. -
William Hiesinger, MD
Associate Professor of Cardiothoracic Surgery (Adult Cardiac Surgery)
BioDr. Hiesinger is a board-certified, fellowship-trained specialist in adult cardiac surgery. He is also an associate professor in the Department of Cardiothoracic Surgery at Stanford University School of Medicine.
Dr. Hiesinger’s clinical focus encompasses the full spectrum of cardiothoracic conditions and treatment approaches, such as heart transplantation, mitral and aortic valve repair, surgical treatment for hypertrophic cardiomyopathy, coronary artery bypass, and complex thoracic aortic procedures. He serves as Surgical Director of the Stanford Mechanical Circulatory Support Program, where he leads and directs the surgical implantation of ventricular assist devices (VADs) in patients with end-stage heart failure.
The National Institutes of Health and the Thoracic Surgery Foundation have awarded funds to support Dr. Hiesinger’s research. In the Stanford Cardiothoracic Therapeutics and Surgery Laboratory, Dr. Hiesinger's research spans the disciplines of computer science and cardiovascular biology, and he endeavors to build novel foundational deep learning systems designed to better represent and process high-dimensional inputs and apply these systems towards clinical problems. Additionally, his lab investigates bioengineered devices, tissue engineering, and angiogenic cytokine therapy for the treatment of heart failure.
He has published extensively and his work has appeared in Nature Communications, Nature Machine Intelligence, the Journal of Heart and Lung Transplantation, Circulation Heart Failure, the Journal of Thoracic and Cardiovascular Surgery, Journal of Vascular Surgery, and elsewhere.
He teaches courses on cardiothoracic surgery skills. He also advises surgeons of the future.
Dr. Hiesinger has won awards for his research and scholarship, including the Surgical Resident of the Year Award, Jonathan E. Rhoads Research Award, Clyde F. Baker Research Prize, and I.S. Ravdin Prize, all from his alma mater, the University of Pennsylvania. He was a finalist for the Vivien Thomas Young Investigator Award from the American Heart Association.
Dr. Hiesinger is a member of the American Association For Thoracic Surgery and serves on the Cardiac Surgery Biology Club. He is also a member of the Society of Thoracic Surgeons and serves on the Workforce on Surgical Treatment of End-Stage Cardiopulmonary Disease national committee as well as the American Heart Association Council for Cardiothoracic and Vascular Surgery. -
John Higgins
Professor of Pathology
Current Research and Scholarly InterestsI work as a diagnostic surgical pathologist doing translational research in renal neoplasia and medical renal disease and neoplastic and medical liver disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology.
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Lynn Hildemann
Senior Associate Dean for Education and Professor of Civil and Environmental Engineering
BioLynn Hildemann's current research areas include the sources and dispersion of airborne particulate matter indoors, and assessment of human exposure to air pollutants.
Prof. Hildemann received BS, MS, and PhD degrees in environmental engineering science from the California Institute of Technology. She is an author on >100 peer-reviewed publications, including two with over 1000 citations each, and another 6 with over 500 citations each. She has been honored with Young Investigator Awards from NSF and ONR, the Kenneth T. Whitby Award from the AAAR (1998), and Stanford's Gores Award for Teaching Excellence (2013); she also was a co-recipient of Atmospheric Environment’s Haagen-Smit Outstanding Paper Award (2001).
She has served on advisory committees for the Bay Area Air Quality Management District and for the California Air Resources Board. She has been an Associate Editor for Environmental Science & Technology, and Aerosol Science and Technology, and has served on the advisory board for the journal Environmental Science & Technology.
At Stanford, Prof. Hildemann has been chair of the Department of Civil & Environmental Engineering, and served as an elected member of the Faculty Senate. She has chaired the School of Engineering Library Committee, the University Committee on Judicial Affairs, and the University Breadth Governance Board. -
Pamela Hinds
Rodney H. Adams Professor in the School of Engineering, Fortinet Founders Chair of the Department of Management Science and Engineering and Professor of Management Science and Engineering
BioPamela J. Hinds is Fortinet Founders Chair and Professor of Management Science & Engineering, Co-Director of the Center on Work, Technology, and Organization and on the Director's Council for the Hasso Plattner Institute of Design. She studies the effect of technology on teams, collaboration, and innovation. Pamela has conducted extensive research on the dynamics of cross-boundary work teams, particularly those spanning national borders. She explores issues of culture, language, identity, conflict, and the role of site visits in promoting knowledge sharing and collaboration. She has published extensively on the relationship between national culture and work practices, particularly exploring how work practices or technologies created in one location are understood and employed at distant sites. Pamela also has a body of research on human-robot interaction in the work environment and the dynamics of human-robot teams. Most recently, Pamela has been looking at the changing nature of work in the face of emerging technologies, including the nature of coordination in open innovation, changes in work and organizing resulting from 3D-printing, and the work of data analysts. Her research has appeared in journals such as Organization Science, Research in Organizational Behavior, Academy of Management Journal, Academy of Management Annals, Academy of Management Discoveries, Human-Computer Interaction, Journal of Applied Psychology, Journal of Experimental Psychology: Applied, and Organizational Behavior and Human Decision Processes. Pamela is a Senior Editor of Organization Science. She is also co-editor with Sara Kiesler of the book Distributed Work (MIT Press). Pamela holds a Ph.D. in Organizational Science and Management from Carnegie Mellon University.
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Karen G. Hirsch, MD
Associate Professor of Neurology (Adult Neurology)
Current Research and Scholarly InterestsDr. Karen G. Hirsch cares for critically ill patients with neurologic disorders in the intensive care unit. Dr. Hirsch's research focuses on using continuous and discrete multi-modal data to develop phenotypes and identify signatures of treatment responsiveness in patients with coma after cardiac arrest. She is the Co-PI of PRECICECAP (PRecision Care In Cardiac ArrEst - ICECAP, NINDS R01 NS119825-01) and works closely with collaborators in data science at Stanford and with industry partners to apply machine learning analyses to the complex multi-modal ICU data. Dr. Hirsch also studies neuro-imaging in post-cardiac arrest coma and traumatic brain injury.
Additional research interests include a broad array of topics and Dr. Hirsch greatly appreciates the importance of team science and collaboration. Along with colleagues in Biomedical Ethics, Dr. Hirsch studies brain death and organ donation with a focus on ethical challenges and prediction models. Along with colleagues in Cardiac Anesthesia and Cardiothoracic Surgery, Dr. Hirsch studies neurologic outcomes in patients on mechanical circulatory support including ECMO.
Dr. Hirsch is broadly interested in improving neurologic outcomes after acute brain injury and identifying early phenotypes to guide precision medicine in neurocritical care, especially in patients with post-cardiac arrest brain injury. -
Daniel Ho
William Benjamin Scott & Luna M. Scott Professor of Law, Professor of Political Science, Senior Fellow at the Stanford Institute for Economic Policy Research, at the Stanford Institute for HAI and Professor, by courtesy, of Computer Science
BioDaniel E. Ho is the William Benjamin Scott and Luna M. Scott Professor of Law, Professor of Political Science, Professor of Computer Science (by courtesy), Senior Fellow at Stanford's Institute for Human-Centered Artificial Intelligence, and Senior Fellow at the Stanford Institute for Economic Policy Research at Stanford University. He is a Faculty Fellow at the Center for Advanced Study in the Behavioral Sciences and is Director of the Regulation, Evaluation, and Governance Lab (RegLab). Ho serves on the National Artificial Intelligence Advisory Commission (NAIAC), advising the White House on artificial intelligence, as Senior Advisor on Responsible AI at the U.S. Department of Labor, and as a Public Member of the Administrative Conference of the United States (ACUS). He received his J.D. from Yale Law School and Ph.D. from Harvard University and clerked for Judge Stephen F. Williams on the U.S. Court of Appeals, District of Columbia Circuit.
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Keith Hodgson
David Mulvane Ehrsam and Edward Curtis Franklin Professor of Chemistry and Professor of Photon Science at SLAC
BioCombining inorganic, biophysical and structural chemistry, Professor Keith Hodgson investigates how structure at molecular and macromolecular levels relates to function. Studies in the Hodgson lab have pioneered the use of synchrotron x-radiation to probe the electronic and structural environment of biomolecules. Recent efforts focus on the applications of x-ray diffraction, scattering and absorption spectroscopy to examine metalloproteins that are important in Earth’s biosphere, such as those that convert nitrogen to ammonia or methane to methanol.
Keith O. Hodgson was born in Virginia in 1947. He studied chemistry at the University of Virginia (B.S. 1969) and University of California, Berkeley (Ph.D. 1972), with a postdoctoral year at the ETH in Zurich. He joined the Stanford Chemistry Department faculty in 1973, starting up a program of fundamental research into the use of x-rays to study chemical and biological structure that made use of the unique capabilities of the Stanford Synchrotron Radiation Lightsource (SSRL). His lab carried out pioneering x-ray absorption and x-ray crystallographic studies of proteins, laying the foundation for a new field now in broad use worldwide. In the early eighties, he began development of one of the world's first synchrotron-based structural molecular biology research and user programs, centered at SSRL. He served as SSRL Director from 1998 to 2005, and SLAC National Accelerator Laboratory (SLAC) Deputy Director (2005-2007) and Associate Laboratory Director for Photon Science (2007-2011).
Today the Hodgson research group investigates how molecular structure at different organizational levels relates to biological and chemical function, using a variety of x-ray absorption, diffraction and scattering techniques. Typical of these molecular structural studies are investigations of metal ions as active sites of biomolecules. His research group develops and utilizes techniques such as x-ray absorption and emission spectroscopy (XAS and XES) to study the electronic and metrical details of a given metal ion in the biomolecule under a variety of natural conditions.
A major area of focus over many years, the active site of the enzyme nitrogenase is responsible for conversion of atmospheric di-nitrogen to ammonia. Using XAS studies at the S, Fe and Mo edge, the Hodgson group has worked to understand the electronic structure as a function of redox in this cluster. They have developed new methods to study long distances in the cluster within and outside the protein. Studies are ongoing to learn how this cluster functions during catalysis and interacts with substrates and inhibitors. Other components of the protein are also under active study.
Additional projects include the study of iron in dioxygen activation and oxidation within the binuclear iron-containing enzyme methane monooxygenase and in cytochrome oxidase. Lab members are also investigating the role of copper in electron transport and in dioxygen activation. Other studies include the electronic structure of iron-sulfur clusters in models and enzymes.
The research group is also focusing on using the next generation of x-ray light sources, the free electron laser. Such a light source, called the LCLS, is also located at SLAC. They are also developing new approaches using x-ray free electron laser radiation to image noncrystalline biomolecules and study chemical reactivity on ultrafast time scales. -
Andrew R. Hoffman
Professor of Medicine (Endocrinology)
Current Research and Scholarly InterestsMechanism of genomic imprinting of insulin like growth factor-2 and other genes.Long range chromatin interactions Role of histone modifications and DNA methylation in gene expression.
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Marie Hollenhorst, MD, PhD
Basic Life Research Scientist, Sarafan ChEM-H
BioDr. Hollenhorst is a physician and scientist with expertise in non-malignant hematology, transfusion medicine, and chemical biology. Dr. Hollenhorst values the one-on-one relationships that she forms with her patients, and strives to deliver the highest quality of care for individuals with blood diseases. Her experience caring for patients drives her to ask scientific questions in the laboratory, where she aims to bring a chemical approach to the study of non-malignant blood disease.
Dr. Hollenhorst pursued combined MD and PhD training at Harvard University, where she received a PhD in Chemical Biology under the mentorship of Professor Christopher T Walsh. She subsequently completed a residency in Internal Medicine at Brigham and Women's Hospital, a fellowship in Transfusion Medicine at Harvard Medical School, and a fellowship in Hematology at Stanford.
Dr. Hollenhorst has an interest in the biology of platelets, which are cellular fragments that help the blood to maintain a healthy balance between bleeding and clotting. Working in the laboratory of Professor Carolyn Bertozzi of Stanford Chemistry, Dr. Hollenhorst is studying sugar molecules found on the surface of platelets that are important in controlling their function and lifespan.
Dr. Hollenhorst's research is supported by an NIH K99 Career Pathway to Independence in Blood Science Award for Physician-Scientists, a Stanford Chemistry, Engineering & Medicine for Human Health Physician-Scientist Fellowship, and a National Blood Foundation Early-Career Scientific Research Grant. -
David Holloway
Raymond A. Spruance Professor of International History, Professor of Political Science and Senior Fellow at the Freeman Spogli Institute for International Studies, Emeritus
Current Research and Scholarly Interestscivil wars; history of nuclear weapons
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Susan Holmes
Professor of Statistics
Current Research and Scholarly InterestsOur lab has been developing tools for the analyses of complex data structures, extending work on multivariate data to structured multitable table that include graphs, networks and trees as well as categorical and continuous measurements.
We created and support the Bioconductor package phyloseq for the analyses of microbial ecology data from the microbiome. We have specialized in developing interactive graphical visualization tools for doing reproducible research in biology. -
Mark Holodniy
Professor of Medicine (Infectious Diseases)
Current Research and Scholarly InterestsMy research program is currently focused in three areas: 1) Translational research (viral evolution and antiviral resistance prevalence and development), 2) Clinical trials (diagnostic assay/medical device, antimicrobials and immunomodulators), and 3) Health services research focusing on public health, infectious diseases and clinical outcomes.
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David S. Hong
Associate Professor of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly InterestsDr. Hong is a child and adolescent psychiatrist and clinician-scientist. His responsibilities span clinical care, teaching/mentorship, and research, with a unifying theme of advancing a developmental cognitive framework as applied to psychiatric conditions. Using this core premise, he work encompasses multiple domains: specialized clinical care, fellowship training, research mentorship, and elaborating the role of sex-specific determinants of development, one of the greatest contributors to individual developmental variation.
His lab investigates genetic and hormonal influences underlying sex differences in child psychiatric conditions. Sex has emerged as a critical variable driving differences in the phenomenology, course, and treatment of many mental health disorders. Unfortunately, an understanding of the biological mechanisms driving these effects are limited. By applying innovative neuroimaging and multiomic approaches, Dr. Hong seeks to provide a deeper understanding of the connection between sex-specific effects and complex psychiatric diseases. To do so, research in the Hong Lab focuses on the role of genes on the X and Y chromosomes, as well as circulating sex hormones on brain development, cognition, and behavior. The lab broadly aims to elucidate the changing nature of these mechanisms across various stages of development.
Another area of focus is the implementation of clinical informatics in child psychiatry and the development of digital mental health tools. As co-Director of the Mental Health Technology and Innovation Hub, Dr. Hong is helping to develop clinical and research infrastructure within the Department of Psychiatry and Behavioral Sciences to advance development of mobile mental health resources that will improve efficacy and access to mental health care. -
Guosong Hong
Assistant Professor of Materials Science and Engineering
BioGuosong Hong's research aims to bridge materials science and neuroscience, and blur the distinction between the living and non-living worlds by developing novel neuroengineering tools to interrogate and manipulate the brain. Specifically, the Hong lab is currently developing ultrasound, infrared, and radiofrequency-based in-vivo neural interfaces with minimal invasiveness, high spatiotemporal resolution, and cell-type specificity.
Dr. Guosong Hong received his PhD in chemistry from Stanford University in 2014, and then carried out postdoctoral studies with at Harvard University. Dr. Hong joined Stanford Materials Science and Engineering and Neurosciences Institute as an assistant professor in 2018. He is a recipient of the NIH Pathway to Independence (K99/R00) Award, the MIT Technology Review ‘35 Innovators Under 35’ Award, the Science PINS Prize for Neuromodulation, the NSF CAREER Award, the Walter J. Gores Award for Excellence in Teaching, and the Rita Allen Foundation Scholars Award. -
Yusuke Hori, MD
Clinical Instructor, Neurosurgery
BioDr. Hori received his MD from Sapporo Medical University, Japan, and during that time he served as a Medical Student Research Fellow in the Department of Pharmacology. He explored the functional role of the SIRT1 gene, a longevity-associated gene, and its association with various conditions such as muscular dystrophy. He also completed a Visiting Student Research Fellowship at the Health Sciences University of Hokkaido and participated in Human Genetics projects focusing on an association between the 27-bp deletion and 538G>A mutation in the ABCC11 Gene.
After graduating from medical school, Dr. Hori completed a neurosurgery residency at National Hospital Organization Okayama Medical Center in Japan. Subsequently, he completed a Stereotactic and Functional Neurosurgery Fellowship and then a Neurosurgical Oncology and Radiosurgery Fellowship at The Cleveland Clinic. He also completed an International Neurosurgery Fellowship at Boston Children's Hospital, Harvard Medical School. In 2022, he moved to Stanford University as a postdoctoral fellow, and under the supervision of Dr. Anca Pasca, he participated in brain organoid research focusing on hypoxic brain injuries.
Since July 2023, Dr. Hori has been working as a Clinical Instructor (Neurosurgical Oncology and Radiosurgery) in the Department of Neurosurgery at Stanford under the supervision of Dr. Steven D. Chang. His clinical interests include malignant brain and spine tumors in both adult and pediatric patients. His clinical research focuses on the application of minimally invasive treatments such as laser interstitial thermal therapy, focused ultrasound, and radiosurgery to treat various neurosurgical conditions. His current lab research aims to develop an organoid model for radiation-induced brain injuries and a high-throughput screening platform to identify novel therapeutic compounds, for which he received a Clinician Educator Grant from Stanford University Maternal and Child Health Research Institute. Outside of medicine, he enjoys playing music including guitar and drums. -
Mark Horowitz
Fortinet Founders Chair of the Department of Electrical Engineering , Yahoo! Founders Professor in the School of Engineering and Professor of Computer Science
BioProfessor Horowitz initially focused on designing high-performance digital systems by combining work in computer-aided design tools, circuit design, and system architecture. During this time, he built a number of early RISC microprocessors, and contributed to the design of early distributed shared memory multiprocessors. In 1990, Dr. Horowitz took leave from Stanford to help start Rambus Inc., a company designing high-bandwidth memory interface technology. After returning in 1991, his research group pioneered many innovations in high-speed link design, and many of today’s high speed link designs are designed by his former students or colleagues from Rambus.
In the 2000s he started a long collaboration with Prof. Levoy on computational photography, which included work that led to the Lytro camera, whose photographs could be refocused after they were captured.. Dr. Horowitz's current research interests are quite broad and span using EE and CS analysis methods to problems in neuro and molecular biology to creating new agile design methodologies for analog and digital VLSI circuits. He remains interested in learning new things, and building interdisciplinary teams. -
Hadi Hosseini
Associate Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly InterestsOur lab’s research portfolio crosses multiple disciplines including computational neuropsychiatry, cognitive neuroscience, multimodal neuroimaging and neurocognitive rehabilitation. Our computational neuropsychiatry research mainly involves investigating alterations in the organization of connectome in various neurodevelopmental and neurocognitive disorders using state of the art neuroimaging techniques (fMRI, sMRI, DWI, functional NIRS) combined with novel computational methods (graph theoretical and multivariate pattern analyses).
The ultimate goal of our research is to translate the findings from computational neuropsychiatry research toward developing personalized interventions. We have been developing personalized interventions that integrate computerized cognitive rehabilitation, real-time functional brain imaging and neurofeedback, as well as virtual reality (VR) tailored toward targeted rehabilitation of the affected brain networks in patients with neurocognitive disorders. -
David Hovsepian, MD
Clinical Professor, Radiology - Pediatric Radiology
Current Research and Scholarly InterestsI am interested in the diagnosis and treatment of vascular malformations in both children and adults; all aspects of gynecological intervention, especially uterine fibroid embolization; and in the developing sciences of quality, safety, and radiology informatics.
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Roger Howe
William E. Ayer Professor of Electrical Engineering, Emeritus
BioDesign and fabrication of sensors and actuators using micro and nanotechnologies, with applications to information processing and energy conversion.
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Brooke Howitt
Associate Professor of Pathology
BioDr. Howitt is a gynecologic and sarcoma pathologist, with academic interests in gynecologic mesenchymal tumors and morphologic and clinical correlates of molecular alterations in gynecologic neoplasia.
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Michael R. Howitt
Assistant Professor of Pathology and of Microbiology and Immunology
Current Research and Scholarly InterestsOur lab is broadly interested in how intestinal microbes shape our immune system to promote both health and disease. Recently we discovered that a type of intestinal epithelial cell, called tuft cells, act as sentinels stationed along the lining of the gut. Tuft cells respond to microbes, including parasites, to initiate type 2 immunity, remodel the epithelium, and alter gut physiology. Surprisingly, these changes to the intestine rely on the same chemosensory pathway found in oral taste cells. Currently, we aim to 1) elucidate the role of specific tuft cell receptors in microbial detection. 2) To understand how protozoa and bacteria within the microbiota impact host immunity. 3) Discover how tuft cells modulate surrounding cells and tissue.
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Alison Hoyt
Assistant Professor of Earth System Science and Center Fellow, by courtesy, at the Woods Institute for the Environment
BioAlison Hoyt is an Assistant Professor of Earth System Science at Stanford. Her work focuses on understanding how biogeochemical cycles respond to human impacts, with a particular focus on the most vulnerable and least understood carbon stocks in the tropics and the Arctic. For more information, please visit her group website here: https://carboncycle.stanford.edu/
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Dimitre Hristov
Associate Professor of Radiation Oncology (Radiation Physics)
Current Research and Scholarly InterestsDevelopment and integration of X-ray, MRI and US imaging technologies for radiation therapy guidance; Design of synergistic approaches to radiation therapy delivery; Treatment planning optimization and modeling.
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Aaron Hsueh
Professor of Obstetrics and Gynecology (Reproductive and Stem Cell Biology), Emeritus
Current Research and Scholarly InterestsHormonal regulation of ovarian function; gonadotropin receptors and related genes, bioinformatic ananlyses of polypeptide hormones and receptors, follicle recruitment and GDF-9; analysis of oocyte and ovarian-expressed genes.
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Yang Hu, MD, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsThe ultimate goal of the laboratory is to develop efficient therapeutic strategies to achieve CNS neural repair, through promoting neuroprotection, axon regeneration and functional recovery.
More specifically, we study retinal ganglion cell (RGC) and optic nerve in various optic neuropathies including traumatic, glaucomatous and inflammatory optic nerve injuries to fully understand the molecular mechanisms of CNS neurodegeneration and axon regeneration failure. -
KC Huang
Professor of Bioengineering and of Microbiology and Immunology
On Leave from 04/01/2024 To 06/30/2024Current Research and Scholarly InterestsHow do cells determine their shape and grow?
How do molecules inside cells get to the right place at the right time?
Our group tries to answer these questions using a systems biology approach, in which we integrate interacting networks of protein and lipids with the physical forces determined by the spatial geometry of the cell. We use theoretical and computational techniques to make predictions that we can verify experimentally using synthetic, chemical, or genetic perturbations. -
Ngan F. Huang
Associate Professor of Cardiothoracic Surgery (Cardiothoracic Surgery Research) and, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsDr. Huang's laboratory aims to understand the chemical and mechanical interactions between extracellular matrix (ECM) proteins and pluripotent stem cells that regulate vascular and myogenic differentiation. The fundamental insights of cell-matrix interactions are applied towards stem cell-based therapies with respect to improving cell survival and regenerative capacity, as well as engineered vascularized tissues for therapeutic transplantation.
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Possu Huang
Assistant Professor of Bioengineering
Current Research and Scholarly InterestsProtein design: molecular engineering, method development and novel therapeutics
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Ting-Ting Huang
Associate Professor (Research) of Neurology (Adult Neurology)
Current Research and Scholarly InterestsWe study the role of oxygen free radicals in oxidative tissue damage and degeneration. Our research tools include transgenic and knockout mice and tissue culture cells for in vitro gene expression.
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Andrew D. Huberman
Associate Professor of Neurobiology and, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsIn 2017, we developed a virtual reality platform to investigate the neural and autonomic mechanisms contributing to fear and anxiety. That involved capturing 360-degree videos of various fear-provoking situations in real life for in-lab VR movies, such as heights and claustrophobia, as well as unusual scenarios like swimming in open water with great white sharks. The primary objective of our VR platform is to develop new tools to help people better manage stress, anxiety and phobias in real-time, as an augment to in-clinic therapies.
In May 2018, we reported the discovery of two novel mammalian brain circuits as a Research Article published in Nature. One circuit promotes fear and anxiety-induced paralysis, while the other fosters confrontational reactions to threats. This led to ongoing research into the involvement of these brain regions in anxiety-related disorders such as phobias and generalized anxiety in humans.
In 2020, we embarked on a collaborative effort with Dr. David Spiegel's laboratory in the Stanford Department of Psychiatry and Behavioral Sciences, aimed to explore how specific respiration patterns synergize with the visual system to influence autonomic arousal and stress, and other brain states, including sleep.
In 2023, the first results of that collaboration were published as a randomized controlled trial in Cell Reports Medicine, demonstrating that specific brief patterns of deliberate respiration are particularly effective in alleviating stress and enhancing mood, and improving sleep.
In a 2021, our collaboration with Dr. Edward Chang, professor and chair of the Department of Neurological Surgery at the University of California, San Francisco (UCSF), was published in Current Biology, revealing that specific patterns of insular cortex neural activity may be linked to, and potentially predict, anxiety responses. -
Adrian Hugenmatter
Director of Protein Engineering
BioDr. Adrian Hugenmatter joined ChEM-H in 2021 and is leading the Protein Therapeutics Knowledge Center. In this role he is also responsible for IMAs Protein Therapeutic module. Dr. Hugenmatter received his PhD in the laboratory of Prof. Donald Hilvert at the Swiss Federal Institute of Zurich (ETH Zurich, Switzerland), where he gained initial experience in enzymology, antibody engineering and directed evolution. Fascinated by protein engineering, he joined the laboratory of Prof. Dan Tawfik at the Weizmann Institute of Science (Israel), where he studied molecular evolution and its application in protein design. Afterwards, Dr. Hugenmatter worked as a research scientist and team leader at Roche for more than a decade. During that time, he was involved in the development and optimization several antibody lead candidates for therapeutic applications in Neuroscience and Oncology.
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John Huguenard
Professor of Neurology (Neurology Research Faculty), of Neurosurgery (Adult Neurosurgery) and, by courtesy, of Molecular and Cellular Physiology
Current Research and Scholarly InterestsWe are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.
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Keith Humphreys
Esther Ting Memorial Professor
Current Research and Scholarly InterestsDr. Humphreys researches individual and societal level interventions for addictive and psychiatric disorders. He focuses particularly on evaluating the outcomes of professionally-administered treatments and peer-operated self-help groups (e.g., Alcoholics Anonymous), and, analyzing the impact of public policies touching addiction, mental health, public health, and public safety.
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Sohail Z Husain
Chambers-Okamura Endowed Professor of Pediatric Gastroenterology
Current Research and Scholarly InterestsMy research delves into three broad areas of the exocrine pancreas: (1) The crucial signaling pathways that initiate and transduce pancreatitis; (2) the factors that turn on pancreatic regeneration and recovery after pancreatic injury; and (3) the mechanisms underlying drug-induced pancreatitis.
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Ruth Huttenhain
Assistant Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsMy group deciphers how G protein-coupled receptors decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses. We exploit quantitative proteomics to capture the spatiotemporal organization of signaling networks combined with functional genomics to study their impact on physiology.
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Gloria Hwang, MD
Clinical Professor, Radiology
Current Research and Scholarly InterestsInterventional oncology, pancreatic interventions, image-guided gene therapy.
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Jackelyn Hwang
Assistant Professor of Sociology
BioJackelyn Hwang is an Assistant Professor in the Department of Sociology and a faculty affiliate at the Center for Comparative Studies in Race and Ethnicity and the Urban Studies Program. Jackelyn’s main research interests are in the fields of urban sociology, race and ethnicity, immigration, and inequality. In particular, her research examines the relationship between how neighborhoods change and the persistence of neighborhood inequality by race and class in US cities. Her current projects focus on the causes and consequences of gentrification and developing automated methods for measuring neighborhood change using Google Street View imagery.
Jackelyn received her B.A.S. in Sociology and Mathematics from Stanford University and her Ph.D. in Sociology and Social Policy from Harvard University. After completing her Ph.D., she was a Postdoctoral Research Fellow in the Office of Population Research at Princeton University. Her research has been supported by the American Sociological Association, the Joint Center for Housing Studies, the National Science Foundation, among others. Her work has appeared in the American Sociological Review, Demography, Social Forces, and other academic journals. -
Joo Ha Hwang, MD, PhD
Professor of Medicine (Gastroenterology and Hepatology) and, by courtesy, of Surgery
Current Research and Scholarly InterestsSpecialize in early detection of gastrointestinal malignancies including esophageal, gastric, pancreatic, bile duct & colon cancers. I have both a clinical & research interest in improving the early detection of gastric cancer in particular. I am the PI of the Gastric Precancerous conditions Study, a prospective study of patients with gastric intestinal metaplasia & other precancerous conditions which combines comprehensive clinical & endoscopic data with a large bio-specimen repository.
