Wu Tsai Human Performance Alliance


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  • Eric S.G. Shaqfeh

    Eric S.G. Shaqfeh

    Lester Levi Carter Professor and Professor of Mechanical Engineering

    Current Research and Scholarly InterestsI have over 25 years experience in theoretical and computational research related to complex fluids following my PhD in 1986. This includes work in suspension mechanics of rigid partlcles (rods), solution mechanics of polymers and most recently suspensions of vesicles, capsules and mixtures of these with rigid particles. My research group is internationally known for pioneering work in all these areas.

  • Carla Shatz

    Carla Shatz

    Sapp Family Provostial Professor and Professor of Biology and of Neurobiology
    On Leave from 09/01/2024 To 08/31/2025

    Current Research and Scholarly InterestsThe goal of research in the Shatz Laboratory is to discover how brain circuits are tuned up by experience during critical periods of development both before and after birth by elucidating cellular and molecular mechanisms that transform early fetal and neonatal brain circuits into mature connections. To discover mechanistic underpinnings of circuit tuning, the lab has conducted functional screens for genes regulated by neural activity and studied their function for vision, learning and memory.

  • Kevin Shea

    Kevin Shea

    Chambers-Okamura Endowed Professor of Pediatric Orthopaedics

    BioKevin G. Shea, MD is at Stanford University. He grew up in Montana and California, graduated from the University of Notre Dame, UCLA School of Medicine, and completed his orthopaedic residency at the University of Utah. His advanced training includes pediatric orthopaedics at Rady Children’s Hospital in San Diego, AO Fellowship in Bern Switzerland with Dr. Ganz (Hip), Dr. Diego Fernandez (Trauma), and Dr. Hans Staubli (sports), Ilizarov Training in Lecco, Italy. He has done the AOSSM South American Traveling Sports Medicine Fellowship, and education in Russia and former Soviet Bloc countries. Most of his early career was in Boise, Idaho. Dr. Shea is a founding member of the PRISM Society (Pediatric Research in Sports Medicine) and the ROCK (Research in Osteochondritis Dissecans of the Knee) Multi-center Study Group, and the SCORE (Sports Cohort Outcomes Research ) Multi-Center Registry for pediatric sports. He has authored more than 270 scientific papers and chapters. His clinic research interests include cartilage and ligament disorders, using pediatric cadaveric tissue and surgical 3D simulations to develop surgeries and improve outcomes for procedures that avoid damage to growth plates. He has years of experience with performance, quality improvement, value, and he worked extensively with the AAOS Quality/Clinical Practice Guideline Committees. He is one of the POSNA members to launch the POSNA Safe Surgery Program. He is a national quality leader in health care with interests in patient safety, risk reduction, and improving value in health care with clinician integration into supply chain. He is an avid cyclist, trail runner, hiker, and spends as much time outside as possible, with his partner Lonnie and their children Beck and Cooper.

  • Krishna Shenoy

    Krishna Shenoy

    Member, Bio-X

    Current Research and Scholarly InterestsWe conduct neuroscience, neuroengineering and translational research to better understand how the brain controls movement, and to design medical systems to assist people with paralysis. These are referred to as brain-machine interfaces (BMIs), brain-computer interfaces (BCIs) and intra-cortical neural prostheses. We conduct this research as part of our Neural Prosthetic Systems Lab (NPSL) and our Neural Prosthetics Translational Lab (NPTL), which I co-direct with Prof. Jaimie Henderson, M.D.

  • Seth Lawrence Sherman, MD

    Seth Lawrence Sherman, MD

    Associate Professor of Orthopaedic Surgery

    Current Research and Scholarly InterestsMy research focuses on ways to augment tissue healing, improve human performance, and prevent musculoskeletal injuries. Approaching these challenges through parallel basic science and clinical pathways, our team works from the “bedside to the bench and back to the bedside”, identifying areas of clinical need to deliver evidence-based solutions for patients.

    We collaborates with orthopaedic surgeons, non-surgical physicians, and researchers within bioengineering, human performance, and musculoskeletal imaging across the Stanford campus. The team is developing novel methods to accurately record human movement (including wearable technology, phone-based systems), rapid MRI imaging protocols, and exploring the use of biomarkers to track injury and recovery. This research builds on my earlier work, which utilized portable, inexpensive software for Microsoft Kinect to detect knee injury risk in youth athletes performing a drop vertical jump test. The team’s multifaceted goal is: 1) develop innovative methods to screen for injury risk (i.e. youth athlete non-contact ACL), 2) create targeted intervention programs to reduce risk, 3) enhance athletic performance; and 4) improve accuracy of return to play testing following injury/surgery (i.e. clinical evaluation, biomarkers, functional tests, imaging analysis for healing).

    In the laboratory,our team investigates cellular and molecular deficiencies in tissue types including tendon, ligament, articular cartilage, and meniscus. By understanding aberrant pathways leading to tissue injury, they can identify innovative therapeutic targets for intervention. In collaboration with the Genetic Engineering and Synthetic Biology laboratories, Dr. Sherman’s research has explored the role of orthobiologic agents such as platelet rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) for tissue healing in patella tendinopathy (the breakdown of collagen in a tendon). Our lab is also investigating the use of CBD for musculoskeletal applications as an alternative to commonly used local anesthetics and cortisone derivatives. In my earlier work, we researched the cellular toxicity of such applications.

    In addition to basic science research, I have helped to build a Sports Medicine clinical research team that includes several full-time clinical research coordinators, residents, fellows, and students. The team collects prospective outcomes on their patients using a novel data collection platform called Patient IQ. The group is part of the JUPITER study which is the largest, multicenter study ever assembled in patellofemoral instability. They are additionally planning to enroll in FDA-approved clinical studies investigating pioneering strategies for knee cartilage restoration, joint preservation, and orthobiologic injections for osteoarthritis. Recent clinical publications explore outcomes in meniscus preservation and transplantation, medial patellofemoral ligament reconstruction, osteochondral allograft and matrix-induced autologous chondrocyte implantation (MACI), and surgical augmentation using PRP/BMAC. The clinical research team actively reports results of non-surgical and surgical interventions to continue to introduce new knowledge to the field, with the goal of improved patient outcome.

  • Matthew Smuck, MD

    Matthew Smuck, MD

    Professor of Orthopaedic Surgery

    Current Research and Scholarly InterestsI direct the Wearable Health Lab at Stanford, investigating medical applications of mobile technology to improve musculoskeletal and neurologic disease detection, treatment and prevention.

  • Michael Snyder, Ph.D.

    Michael Snyder, Ph.D.

    Stanford W. Ascherman Professor of Genetics
    On Partial Leave from 12/02/2024 To 12/01/2025

    Current Research and Scholarly InterestsOur laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states