School of Engineering
Showing 251-279 of 279 Results
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Jian Xiong
Postdoctoral Scholar, Chemical Engineering
BioI thrive to understand the roles of lysosomes in physiological and pathological conditions. Lysosomes are both degradation compartment and metabolic controlling hub, and dysregulation of lysosomal functions are frequently implicated in a vast number of diseases including neurodegenerative diseases, however, the systematic knowledge of the molecular mechanism by which lysosomal contributes to these diseases is lacking. Ion channels are the primary mediators of neuronal activity, defects in neuronal ion channel activity are linked with many kinds of neurodegenerative diseases. Interestingly, besides typical ion channels that are involved in the neuronal activity, defects in lysosomal ion channels, such as TRPML1, CLN7 and CLC-7 are also implicated in neuropathy. My previous work as Ph.D student in University of Texas MD Anderson Cancer Center focused on regulation of lysosomal function by ion channels and metabolites. I discovered a mechanism of lysosomal Na+ channel regulate mTORC1 activation by regulating lysosomal amino acid accumulation. I also discovered role of glutamine in controlling lysosomal degradation capacity. In the meantime, I developed novel methods to isolate organelles. My ultimate research goal is to understand the key developmental pathways and how alterations in gene sequences and expression contribute to human disease, therefore, I am pursuing independent academic researcher as my career goal. Starting Feb 2022, I work with Dr. Monther Abu-Remaileh at Stanford University on role of lysosomes in neurodegenerative diseases. I use genetics, chemical biology and omics approaches to study lysosome function under various physiological and pathological conditions, especially age-associated neurodegenerative disorders, and monogenic neurodegenerative lysosome storage diseases. In Stanford, I aim to integrate ionic regulation, metabolomic regulation and functional proteomic regulation to systematically understand the biology of lysosome in physiological conditions and pathological conditions.
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Chengyi Xu
Postdoctoral Scholar, Chemical Engineering
BioSkin-inspired sensing and actuating technologies: from cephalopod camouflage to human tactile perception
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Do Y. Yoon
Adjunct Professor, Chemical Engineering
BioDo Y. Yoon is Adjunct Professor of Chemical Engineering at Stanford University since 2012. He obtained his B.S. in Chemical Engineering from Seoul National University, Korea (1969), and earned his Ph.D. in Polymer Science and Engineering from University of Massachusetts Amherst, working with Richard S. Stein (1973). He did his postdoctoral study with Paul J. Flory in Chemistry Department of Stanford University (1973-1975). He then worked in IBM Research Laboratory in San Jose, California as Research Staff Member and Manager of Polymer Physics Group (1975-1999). From 1999 to 2012, he was Professor of Chemistry at Seoul National University, Korea, and served as the Korean spokesperson of the Germany-Korea International Research Training Group on “Self-organized Materials for Optoelectronics” (2006-2012). He published about 260 research papers (h-index: 72), was elected a fellow of American Physical Society (1985), received Humboldt Research Award by the Alexander von Humboldt Foundation of Germany (1999), and received Academic Achievements Award from the Alumni Association of Seoul National University (2017). His research areas included molecular conformations & dynamics, semicrystalline molecular morphology, liquid crystalline state, surface and thin film characteristics of polymers, and structure-property relationships of polymers for information technology, organic electronics, and clean energy. He is a co-editor of "Selected Works of Paul J. Flory" and a co-author of "Paul John Flory: A Life of Science and Friends."
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Maha Yusuf
Ph.D. Student in Chemical Engineering, admitted Autumn 2015
Current Research and Scholarly InterestsLong charging times of lithium-ion batteries (LIBs) is a major bottleneck in the widespread deployment of electric vehicles (EVs). There is a global push to enable extreme fast charging (XFC) of EV batteries to reduce their charging times to 10-15 minutes. But existing LIBs cannot achieve this goal without significantly reducing battery performance. This is mainly attributed to a phenomenon, known as “Li plating,” as the battery is charged fast. In this thesis, I use neutron and X-ray-based imaging to visualize the battery electrode to investigate Li plating at elevated charging rates.
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Roseanna N. Zia
Associate Professor of Chemical Engineering
Current Research and Scholarly InterestsMy lab unifies mesoscale physics and chemistry with cellular-level biology through novel theoretical modeling and large-scale computational simulations. We work in four areas: 1) constructing micro-continuum theory of complex fluids; 2) mechanistically explaining non-equilibrium phase transitions in colloidal systems; 3) modeling confined and large-scale hydrodynamically-interacting colloidal suspensions; and 4) modeling the physics of living cells.
