School of Humanities and Sciences
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Xia Li (Lisa)
Basic Life Res Scientist, Biology
Current Research and Scholarly InterestsMy current research focuses on how aging-associated loss of proteome homeostasis (proteostasis) and organelle dysfunction, particularly lysosomal impairment, drive selective neuronal vulnerability in Parkinson’s disease. I integrate mechanistic biochemistry with neuronal cell biology to define how protein aggregates disrupt lysosomal function and how proteostasis and lysosome contributes to neuronal dysfunction and disease pathology.
