School of Medicine
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Francisco Galdos
Affiliate, Department Funds
Fellow in Pediatrics - CardiologyBioFrancisco earned his undergraduate degree in Human Developmental and Regenerative Biology from Harvard University, graduating magna cum laude. He subsequently completed his MD/PhD at Stanford University School of Medicine. During his doctoral training under the mentorship of Dr. Sean Wu, Francisco published one of the first comprehensive maps of human cardiac cell development using pluripotent stem cell-based models. His research contributed to the development of machine learning tools and genetic tracing systems that identified and characterized human left ventricular cardiomyocytes in vitro, enabling the modeling of left ventricular development in hypoplastic left heart syndrome. Francisco has authored multiple first-author publications and has been awarded funding from both internal sources and the NIH (F30, T32). He has received numerous accolades for his work, including the prestigious Harold Weintraub Award, and has presented his research at various national conferences. As part of the accelerated research pathway at Stanford, Francisco is focused on the genetic and epigenetic mechanisms underlying heart failure and heart development in congenital heart disease, with the ultimate goal of developing novel therapeutics for pediatric patients.
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Jacqueline Genovese
Academic Prog Prof 3, School of Medicine - Biomedical Ethics
Current Role at StanfordExecutive Director of the Medicine & the Muse Program
LEAD Program for Residents, Mentor (2021-2024)
Member of Stanford School of Medicine Staff Collective
Steering Committee Member: Health Humanities Consortium (2019-2024)
Teaching Lead, War Literature & Writing class for military affiliated students
Co-teacher, War and Fiction for non military and military affiliated students (2017-2109)
Facilitator, Literature & Medicine Dinner & Discussion Series
Co-Lead: Frankenstein@200 2017-2018 Initiative
Member of Stanford Medicine Arts & Mindfulness Committee (Stanford Health) -
Paul George, MD, PhD
Associate Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsDEVELOPMENT OF STROKE RECOVERY THERAPEUTICS:
Stroke is devastating to patients and their caregivers. We currently are investigating 3 neural repair approaches. The first focuses on developing a stroke recovery therapeutic based on an essential repair pathway and how it alters the immune response following stroke. The second utilizes implantable, conductive polymer devices to electrically manipulate the recovering nervous system to improve recovery and identify novel therapeutic targets. The final approach works to optimize stem cell therapeutics to enhance their ability to treat patients who have suffered from neural injury.
CONDUCTIVE BIOPOLYMER SYSTEMS FOR NEURAL RECOVERY AND STEM CELL MODULATION:
The George lab develops biomaterials to improve neural recovery in the peripheral and central nervous systems. By controlled release of drugs and molecules through biomaterials we can study the temporal effect of these neurotrophic factors on neural recovery and engineer drug delivery systems to enhance regenerative effects. By identifying the critical mechanisms for neural recovery, we are able to develop polymeric technologies for clinical translation in nerve regeneration. Recent work utilizes these novel conductive polymers to differentiate stem cells for therapeutic and drug discovery applications.
APPLYING ENGINEERING TECHNIQUES TO DETERMINE BIOMARKERS FOR STROKE DIAGNOSTICS:
The ability to create diagnostic assays and techniques enables us to understand biological systems more completely and improve clinical management. Previous work utilized mass spectroscopy proteomics to find a simple serum biomarker for TIAs (a warning sign of stroke). Our study discovered a novel candidate marker, platelet basic protein. Current studies are underway to identify further candidate biomarkers using transcriptome analysis. More accurate diagnosis will allow for aggressive therapies to prevent subsequent strokes.