Institute for Stem Cell Biology and Regenerative Medicine
Showing 21-40 of 136 Results
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Michael F. Clarke, M.D.
Karel H. and Avice N. Beekhuis Professor of Cancer Biology
Current Research and Scholarly InterestsDr. Clarke maintains a laboratory focused on two areas of research: i) the control of self-renewal of normal stem cells and diseases such as cancer and hereditary diseases; and ii) the identification and characterization of cancer stem cells. His laboratory is investigating how perturbations of stem cell regulatory machinery contributes to human disease. In particular, the laboratory is investigating epigenetic regulators of self renewal, the process by which stem cells regenerate themselves.
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Agnieszka Czechowicz, MD, PhD
Assistant Professor of Pediatrics (Stem Cell Transplantation)
Current Research and Scholarly InterestsDr. Czechowicz’s research is aimed at understanding how hematopoietic stem cells interact with their microenvironment in order to subsequently modulate these interactions to improve bone marrow transplantation and unlock biological secrets that further enable regenerative medicine broadly. This work can be applied across a variety of disease states ranging from rare genetic diseases, autoimmune diseases, solid organ transplantation, microbiome-augmentation and cancer.
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Thiago Almeida Pereira
Instructor, Institute for Stem Cell Biology and Regenerative Medicine
Current Research and Scholarly InterestsMy research focus on fibrosis pathogenesis, identifying key pathways for therapeutic intervention and biomarker discovery. I'm currently investigating the Hedgehog pathway in liver and lung fibrotic diseases, such as schistosomiasis mansoni, alcoholic and non-alcoholic fatty liver disease, viral hepatitis B and C, idiopathic pulmonary fibrosis. I'm also investigating the role of tumor associated macrophages and cancer associated fibroblasts in liver and head and neck cancers.
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Tushar Desai
Professor of Medicine (Pulmonary, Allergy and Critical Care Medicine)
Current Research and Scholarly InterestsBasic and translational research in lung stem cell biology, cancer, pulmonary fibrosis, COPD, and acute lung injury/ARDS. Upper airway stem cell CRISPR gene correction followed by autologous stem cell transplantation to treat Cystic fibrosis. Using lung organoids and precision cut lung slice cultures of mouse and human lungs to study molecular regulation of lung stem cells. Using transgenic mice to visualize Wnt protein transmission from niche cell to stem cell in vivo.
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Maximilian Diehn, MD, PhD
Jack, Lulu, and Sam Willson Professor and Professor of Radiation Oncology (Radiation Therapy)
Current Research and Scholarly InterestsMy laboratory focuses on two main areas: 1) cancer stem cell biology and 2) novel biomarkers for identifying the presence of malignant cells (diagnostic), predicting outcome (prognostic), and predicting response to therapy (predictive). Areas of study include cancers of the lung, breast, and gastrointestinal system. Clinically I specialize in the treatment of lung cancer and applications of stereotactic ablative radiotherapy and perform both prospective and retrospective clinical studies.
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Francisco Galdos
MD Student, expected graduation Spring 2024
Ph.D. Student in Stem Cell Biology and Regenerative Medicine, admitted Summer 2017
MSTP StudentBioMy journey to pursue the physician-scientist track stems from an early fascination with biology and my family’s eight-year struggle to save my younger brother’s life. My brother was born with a complex congenital heart defect known as Hypoplastic Left Heart Syndrome (HLHS). In 2003, my brother received a heart transplant, but despite this, he passed away in 2004. Growing up, I strived to find an explanation for my brother’s congenital heart defect and became interested in medicine at a young age. Looking to pursue this goal, I attended the Michael DeBakey High School for Health Professions, a top pre-health and science public school, and in 2011 I was accepted to Harvard University where I pursued a major in the department of Stem Cell and Regenerative Biology. During my college years I took classes in developmental and stem cell biology where I became interested in the use of these fields to understand congenital defects. I began my research career in Drs. Caroline and Geoffrey Burn’s lab studying the development of the great vessels of the heart in zebrafish, Throughout my time at Harvard, I was awarded numerous fellowships that supported my undergraduate research, including the prestigious Amgen Scholars Fellowship that supported summer research in Dr. Michael Longaker’s lab at Stanford University. I pursued my undergraduate honors thesis in Dr. Richard Lee’s laboratory where I identified the role of Apolipoprotein E as a factor necessary for maintaining mature beta cell gene expression. These experiences culminated in my decision to apply to the physician-scientist program at Stanford University where I am currently training to pursue a career in academic medicine with the ultimate goal of practicing as a pediatric cardiologist and a university professor with an active laboratory. Currently, I am a graduate student in Dr. Sean Wu’s laboratory where I study the development of ventricular development in the heart using both bioinformatic approaches such as scRNA-seq and human induced pluripotent stem cells to study the development of the left and right ventricles. Through my work, I aim to understand the mechanisms that give rise to single ventricle congenital heart defects with the hope of making a difference in the lives of children born with these diseases.
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Heather Gentner
Director of Finance and Administration (SoM), Stem Cell Bio Regenerative Med Institute
Current Role at StanfordI am the Director of Finance and Administration for the Institute for Stem Cell Biology and Regenerative Medicine (ISCBRM) in the School of Medicine. I oversee and carry out administrative and financial related functions for the department.