Pediatrics
Showing 401-450 of 856 Results
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Chaitan Khosla
Wells H. Rauser and Harold M. Petiprin Professor and Professor of Chemistry and, by courtesy, of Biochemistry
Current Research and Scholarly InterestsResearch in this laboratory focuses on problems where deep insights into enzymology and metabolism can be harnessed to improve human health.
For the past two decades, we have studied and engineered enzymatic assembly lines called polyketide synthases that catalyze the biosynthesis of structurally complex and medicinally fascinating antibiotics in bacteria. An example of such an assembly line is found in the erythromycin biosynthetic pathway. Our current focus is on understanding the structure and mechanism of this polyketide synthase. At the same time, we are developing methods to decode the vast and growing number of orphan polyketide assembly lines in the sequence databases.
For more than a decade, we have also investigated the pathogenesis of celiac disease, an autoimmune disorder of the small intestine, with the goal of discovering therapies and related management tools for this widespread but overlooked disease. Ongoing efforts focus on understanding the pivotal role of transglutaminase 2 in triggering the inflammatory response to dietary gluten in the celiac intestine. -
Joseph Kim
Clinical Professor, Pediatrics
BioJoseph J. Kim, MD is a Clinical Associate Professor of Pediatrics and Emergency Medicine at the Stanford University School of Medicine. Dr. Kim also serves as the Chief of the Division of Pediatric Hospital Medicine at Stanford University and as the Associate Chief Medical Officer of Stanford Children’s Health. Dr. Kim’s career has focused on medical leadership and program building in pediatric hospital medicine. He has been active locally and nationally promoting patient experience, with particular emphasis on family centered care in pediatric inpatient settings. He has participated in numerous local and national care improvement programs including efforts around bronchiolitis, inpatient asthma management, pediatric sedation, medical co-management of surgical patients and patient care progression in inpatient settings. In his hospital administrative roles he has championed safety rounding, family centered rounding, scheduled based care of inpatients, discharge planning and value based performance improvement. Dr. Kim has mentored dozens of trainees and junior faculty in healthcare leadership and program administration.
Dr. Kim received his BA in Sociology from the University of Virginia and his MD from SUNY Upstate Medical University in Syracuse. He completed his residency in pediatrics at the University of California San Francisco. Clinically, Dr. Kim practices as a Pediatric Hospitalist at Lucile Packard Children’s Hospital Stanford and at California Pacific Medical Center. -
Juliann Lipps Kim
Adjunct Clinical Professor, Pediatrics - General Pediatrics
BioDr. Juliann Kim works as a Pediatric Hospitalist for PAMF. She cares for patients in the LPCH Newborn Nursery, Packard Intermediate Care Nursery, and on the inpatient wards. She serves on several LPCH committees including Professional Performance Evaluation Committee, Perinatal Care Committee, Credentials Committee, and Care Improvement Committee. She served as the LPCH Medical Staff President from 2018-2020.
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Seung K. Kim M.D., Ph.D.
KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
Current Research and Scholarly InterestsPancreatic islets are essential for human health. We study the development and function of islet cells using modern methods in several model systems, including mice, pigs, human pancreas, primates, embryonic stem cells, and fruit flies. We have discovered critical factors required for islet development and mature islet cell function. These approaches have informed efforts to generate replacement islets, and provide immune protection of transplanted islets for diabetes.
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Yong Yean Kim
Assistant Professor of Pediatrics ( Hematology & Oncology)
BioOur lab is interested in translational science to bring new therapies to clinical trials. In particular, we are interested in pediatric sarcomas which have not had advancement in clinical treatment for decades. Current projects in the lab focus on understanding of the biology of fusion transcription factor PAX3::FOXO1 which is the driver mutation in fusion positive rhabdomyosarcoma. PAX3::FOXO1 is a powerful oncogenic transcription factor which rewires the transcriptional organization to lock the cancer cell in the proliferative state. Since transcription factors including PAX3::FOXO1 are difficult to target using small molecules, we aim to understand how PAX3::FOXO1 is regulated and targeting the regulators of PAX3::FOXO1. By understanding and targeting the regulation of PAX3::FOXO1, we hope to bring new therapies for fusion positive rhabdomyosarcoma. Additionally, these regulatory mechanisms may also be active in other transcription driven cancers such as the EWSR1::FLI1 driven Ewings Sarcoma.
Our lab is also interested in exploring the epigenetic landscape of pediatric solid tumors and trying to understand how dysregulation in the epigenome drives oncogenesis. We utilize various CRISPR mediated genetic techniques to interrogate the regulators of epigenome focusing on the histone lysine demethylases (KDMs). KDMs are an understudied group of epigenetic regulators which can be targeted for therapeutic effect. We explore the role of KDMs in pediatric solid tumors and hope to identify potential targets for drug development. -
Alaina Kipps
Clinical Professor, Pediatrics - Cardiology
BioDr. Kipps grew up in Santa Cruz, California and completed her medical degree at Harvard Medical School in 2003. After general pediatrics residency at Stanford, she completed pediatric cardiology fellowship at Boston Children’s Hospital from 2006 to 2009. After three years on faculty with University of California, San Francisco she was recruited back to Stanford in 2012 to become the medical director for acute care cardiology (2013-2021). Since 2021 she has focused on QI for the ACCU and heart center, and has served as the ACCU local improvement team medical director since 2013. In 2014 she co-founded the Pediatric Acute Care Cardiology Collaborative (PAC³) with Nicolas Madsen and co-directed this since inception to spring 2026. PAC³ has 50 participating centers, a registry since 2019 with >150,000 encounters, and is the academic society for the ACCU subspecialty. Her academic focus is in clinical effectiveness and quality improvement science, and she completed her Masters of Science in Epidemiology at Harvard School of Public Health in 2016. Her other significant interest is in teaching, mentorship, and coaching. She is the co-director of the Pediatric residency program scholarly concentration in Quality Improvement, co-leads the Pediatric department peer scholar community (in QI), and has served as a residency coach since 2020.
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Varvara A. Kirchner
Associate Professor of Surgery (Abdominal Transplantation) and, by courtesy, of Pediatrics
BioDr. Kirchner completed her medical school, surgical residency and multi-organ transplant fellowship in adult and pediatric liver, pancreas, kidney transplantation and total pancreatectomy with islet auto-transplantation at the University of Minnesota. She underwent further training in living donor liver transplantation and hepatobiliary surgery at the Asan Medical Center, Seoul, South Korea. Her clinical practice involves living and deceased donor liver and kidney transplantation in adult and pediatric patients as well as total pancreatectomy with islet auto-transplantation for patients with chronic and acute recurrent pancreatitis. She currently serves as Surgical Director of the Islet Cell Auto-Transplant at Stanford Children’s and Associate Director of the Living Donor Liver Transplant Program at the Division of Abdominal Transplantation. Dr. Kirchner’s research focuses on the biology of aging, cellular and solid organ transplantation. Her specific interests are in auto-islet transplantation, iPSC-derived hepatocyte therapies and liver regeneration. Dr. Kirchner's research on the impact of donor age on generation of iPSC-derived hepatocyte-like cells is supported by the NIA K08 Faculty Development Award. She is an active member of the American Society of Transplant Surgeons and the International Liver Transplantation Society.
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Jonathan D Klein
Marron and Mary Elizabeth Kendrick Professor of Pediatrics
Current Research and Scholarly InterestsMy studies address:
1. Confidentiality and Access to Care studies of confidential time during well-visits and policy analyses addressing quality of care and health systems capacity for adolescents and young adults in the US and globally; and,
2, Tobacco, nicotine, and second-hand smoke studies of primary care counseling to reduce nicotine addiction in adolescents and programs to engage medical specialty groups in secondhand smoke clinical and policy interventions. -
Juliet Klasing Knowles
Assistant Professor of Neurology and Neurological Sciences (Pediatric Neurology) and of Pediatrics
Current Research and Scholarly InterestsThe Knowles lab studies how white matter structure changes in different forms of epilepsy, and how aberrant white matter structure, in turn, shapes neuronal network function. In mouse models, we use a variety of innovative tools including neurophysiology, quantitative EEG, behavior, histological measures of white matter structure and MR imaging. We also conduct clinical research to study white matter abnormalities in children with epilepsy.
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Euna Koo, MD
Clinical Associate Professor, Ophthalmology
Clinical Assistant Professor (By courtesy), PediatricsBioDr. Koo is an ophthalmologist specializing in pediatric ophthalmology and adult strabismus. She received her ophthalmology training at UC San Francisco and then her fellowship training in pediatric ophthalmology and adult strabismus at Boston Children's Hospital affiliated with Harvard Medical School. She has been board certified by the American Board of Ophthalmology since 2016. Her practice reflects her clinical interests in pediatric ophthalmology and in adult strabismus.
She utilizes Botox in management of adult and pediatric strabismus. She also uses hidden adjustable sutures in children and adults to optimize alignment of eyes with surgery. Muscles can be adjusted up to 7-10 days after surgery.
She is active in training both residents and fellows in ophthalmology. -
Alan M. Krensky, M.D.
Shelagh Galligan Professor in the School of Medicine, Emeritus
Current Research and Scholarly InterestsMechanisms and therapies for infection, cancer, autoimmunity and transplantation.
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Calvin Kuo
Maureen Lyles D'Ambrogio Professor
Current Research and Scholarly InterestsWe study cancer biology, intestinal stem cells (ISC), and angiogenesis. We use primary organoid cultures of diverse tissues and tumor biopsies for immunotherapy modeling, oncogene functional screening and stem cell biology. Angiogenesis projects include blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy. ISC projects apply organoid culture and ko mice to injury-inducible vs homeostatic stem cells and symmetric division mechanisms.
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Christin S Kuo
Assistant Professor of Pediatrics (Pulmonary Medicine)
BioDr. Christin Kuo is a physician-scientist in the Department of Pediatrics. The ultimate goal of her research is to integrate a cellular and molecular understanding of pulmonary neuroendocrine cells (PNECs) to discover new approaches for diagnosing and treating diverse respiratory conditions associated with NE cell dysfunction and excessive proliferation, including neuroendocrine tumors. Abnormal PNECs are found in neuroendocrine cell hyperplasia of infancy (NEHI), pulmonary carcinoids, large cell neuroendocrine carcinoma, and small cell lung cancer. Her innovative approaches to studying the development and molecular diversity of rare but fascinating neurosensory cells with single cell precision, have led to fundamental discoveries. Her lab’s current research aims to apply this knowledge to understanding diverse human pulmonary neuroendocrine cell disorders using interdisciplinary approaches. Dr. Kuo is a Maternal and Child Health Research Institute Faculty Scholar.
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Angelle Desiree LaBeaud
Professor of Pediatrics (Infectious Diseases), Senior Fellow at the Woods Institute for the Environment and Professor, by courtesy, of Epidemiology and Population Health and of Environmental Social Sciences
Current Research and Scholarly InterestsArthropod-borne viruses are emerging and re-emerging infections that are spreading throughout the world. Our laboratory investigates the epidemiology of arboviral infections, focusing on the burden of disease and the long-term complications on human health. In particular, Dr. LaBeaud investigates dengue, chikungunya, and Rift Valley fever viruses in Kenya, where outbreaks cause fever, arthritis, retinitis, encephalitis, and hemorrhagic fever. Our main research questions focus on the risk factors for arboviral infections, the development of diagnostic tests that can be administered in the field to quickly determine what kind of arboviral infection a person has, and the genetic and immunologic investigation of why different people respond differently to the same infection. Our long-term goals are to contribute to a deeper understanding of arboviral infections and their long-term health consequences and to optimize control strategies to prevent these emerging infections. Our laboratory also investigates the effects of antenatal and postnatal parasitic infections on vaccine responses, growth, and development of Kenyan children.
My lab at Stanford supports the field work that is ongoing in Kenya, but we also have several projects that are based locally. We strive to improve diagnostics of arboviral infections and are using Luminex technology to build a new screening assay. We also have created a Luminex based platform to assess vaccine responses against multiple pathogens. -
Norman J. Lacayo, MD
Associate Professor of Pediatrics (Hematology and Oncology)
Current Research and Scholarly InterestsPediatric Hematology/Oncology, Phase I drug studies for refractory and relapsed leukemia; genomic studies, biologic risk-stratification and treatment of acute myeloid leukemia; prediction or induction response and risk of relapse using phosphoproteomics in childhood AML; novel MRD techniques in childhood ALL.
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Rayhan A. Lal, MD
Assistant Professor of Medicine (Endocrinology) and of Pediatrics (Endocrinology)
BioI grew up in the east bay area and have had type 1 diabetes for 30+ years. I studied electrical engineering and computer science at U.C. Berkeley (Go Bears!) with the hope of applying my knowledge to diabetes technology. The significance of clinical practice became clear to me after my siblings also developed diabetes. I am devoting my life to advancing the care of diabetes in people of all ages.
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Scott R. Lambert, MD
Professor of Ophthalmology and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsMy research has focused on improving the visual outcomes of children with congenital cataracts. I organized a randomized clinical trial, the Infant Aphakia Treatment Study to compare the visual outcomes of infants optically corrected with a contact lens vs. an intraocular lens after unilateral cataract surgery. A second area of research has been ocular growth after cataract surgery.
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Bomi Lee
Assistant Professor of Pediatrics (Gastroenterology, Hepatology, and Nutrition)
Current Research and Scholarly InterestsMy lab is dedicated to unraveling the complexities of the immune microenvironment and its role in the pathogenesis of pancreatic diseases, such as pancreatitis and pancreatic cancer. By leveraging cutting-edge technology, innovative experimental and genetic animal models, as well as human specimens from donors, we aim to identify novel immune markers and potential therapeutic targets. Our goal is to advance the understanding of immune cells and their contributions to these diseases and to transl
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Grace Lee
Professor of Pediatrics (Infectious Diseases)
BioDr. Grace Lee is Chief Quality Officer and the Christopher G. Dawes Endowed Director of Quality at Stanford Medicine Children’s Health and Lucile Packard Children’s Hospital Stanford, and Associate Dean for Maternal and Child Health (Quality and Safety) and Professor of Pediatrics at Stanford University School of Medicine. She oversees the Center for Pediatric and Maternal Value that seeks to improve quality, safety, patient experience and health equity across the organization. Dr. Lee previously served as a member of the Institute of Medicine Committee (IOM) to Review Priorities in the National Vaccine Plan, the IOM Committee on the Ethical and Scientific Issues in Studying the Safety of Approved Drugs, the National Academies of Sciences, Engineering, and Medicine (NASEM) Committee on Vaccine Research and Development Recommendations for Advancing Pandemic and Seasonal Influenza Preparedness and Response, and AHRQ's Healthcare Safety and Quality Improvement Research Study Section. She also served as a Board Member for the Society for Healthcare Epidemiology of America (SHEA), Pediatric Infectious Diseases Society (PIDS), and the National Academy of Medicine (NAM) Board on Population Health and Public Health Practice. She was previously the Chair of the U.S. Advisory Committee on Immunization Practices (ACIP) that recommends vaccines for the U.S. population, and she is an elected member of the National Academy of Medicine.
