School of Medicine


Showing 1-49 of 49 Results

  • Bereketeab Haileselassie

    Bereketeab Haileselassie

    Assistant Professor of Pediatrics (Critical Care)

    Current Research and Scholarly InterestsMy laboratory is focused on understanding the cellular mechanisms which mediate end-organ failure in pediatric sepsis. Our current work focuses on determining the role of altered mitochondrial dynamics in sepsis-induced multi-organ dysfunction syndrome (MODS). Specifically, we focus on understanding the mechanisms that mediate derangements in mitochondrial fission and autophagy in sepsis.

  • Jens Hainmueller

    Jens Hainmueller

    Kimberly Glenn Professor and Professor of Political Science

    BioJens Hainmueller is the Kimberly Glenn Professor of Political Science and Director of Graduate Studies in Stanford University’s Department of Political Science. He co-directs the Stanford Immigration Policy Lab and is a Faculty Affiliate at the Stanford Center for Causal Science, the Institute for Human-Centered Artificial Intelligence, and the Europe Center. He is also a member of the Maternal & Child Health Research Institute at Stanford’s School of Medicine.

    Hainmueller’s research spans statistical methods, causal inference, immigration, and political economy, and he has published nearly 70 articles with over 40,000 citations. Many of his works appear in top journals, including Science, Nature, and PNAS, as well as leading field journals in political science, statistics, economics, and business.

    He has developed widely adopted statistical methods—such as synthetic control methods, entropy balancing, Average Marginal Component Effects, and GeoMatch algorithms—and created several open-source software packages that support empirical research across disciplines. At Stanford, he teaches courses on causal inference and data science.

    Hainmueller’s contributions have earned him prestigious awards, including the Gosnell Prize for Excellence in Political Methodology, the Warren Miller Prize, the Robert H. Durr Award, and the Emerging Scholar Award from the Society of Political Methodology. He is an Andrew Carnegie Fellow, an elected Fellow of the Society of Political Methodology, and holds an honorary degree from the European University Institute (EUI).

    He earned his PhD from Harvard University, with additional studies at the London School of Economics, Brown University, and the University of Tuebingen. Before joining Stanford, he was a faculty member at the Massachusetts Institute of Technology (MIT).

    For a full list of his publications, please refer to his Google Scholar Citation Page and CV.

  • Lou Halamek

    Lou Halamek

    Professor of Pediatrics (Neonatology) and, by courtesy, of Obstetrics and Gynecology

    Current Research and Scholarly Interests1. development of hospital operations centers coupled with sophisticated simulation capabilities
    2. re-creation of near misses and adverse events
    3. optimizing human and system performance during resuscitation
    4. optimizing pattern recognition and situational awareness at the bedside
    5. evaluation and optimization of debriefing
    6. patient simulator design

  • Scott S. Hall, Ph.D

    Scott S. Hall, Ph.D

    Professor of Psychiatry and Behavioral Sciences (Child and Adolescent Psychiatry and Child Development)

    Current Research and Scholarly InterestsMy primary area of scholarly and clinical interest is the pathogenesis of problem behaviors shown by individuals diagnosed with intellectual and developmental disabilities (IDD), particularly those with neurogenetic forms of IDD, such as fragile X syndrome, Cornelia de Lange syndrome and Prader-Willi syndrome. My work aims to both advance understanding of these disorders and to identify effective new treatment approaches for pediatric and adult patient populations by state-of-the-art methodologies, such as brain imaging, eye tracking and functional analysis to determine how environmental and biological factors affect the development of aberrant behaviors in these syndromes. The end goal of my research is to create patient-specific methods for treating the symptoms of these disorders.

  • Joachim Hallmayer

    Joachim Hallmayer

    Professor of Psychiatry and Behavioral Sciences (Child and Adolescent Psychiatry and Child Development)
    On Partial Leave from 09/01/2024 To 08/31/2026

    Current Research and Scholarly InterestsPrincipal Investigator
    Infrastructure to facilitate discovery of autism genes
    The purpose of this project is to facilitate the discovery of the genes that contribute autism by maintaining an infrastructure which research groups studying the genetics of autism can work collaboratively. This will be
    accomplished through workshops, a Virtual Private Network, and access to a database that includes phenotype and genotype data from all participating groups.

    Principal Investigator
    A California Population-Based Twin Study of Autism
    This will address several fundamental questions: (1) What is the heritability of autism (2) What is the contribution of genetic factors to variation in symptom dimensions? (3) Is there a continuum between the quantitative neurocognitive traits and clinical disorder? (4) What proportion of the variance in the neurocognitive traits is accounted for by genetic and non-genetic factors?

    Co-Investigator
    Center for Integrating Ethics in Genetics Research(Cho)
    The goal of this project is to serve as a center of excellence in neurogenetics research, to develop a national model for bench, to bedside research ethics consultation, and to provide training opportunity in biomedical ethics.

    Co-Investigator
    Gene, Brain and Behavior in Turner Syndrome(Reiss)
    The primary objective of this project is to use advanced, multi-modal magnetic resonance imaging (MRI) techniques, analyses of X chromosome parent-of-origin and cognitive-behavioral assessment to elucidate the effects of monosomy and X-linked imprinting on neurodevelopment and neural function in a large cohort of young girls with Turner syndrome, pre-estrogen replacement.

    Project Director
    Project F: Genomic Analysis in narcolepsy cataplexy
    The goal of the project is to locate genes outside the HLA region that influence susceptibility to narcolepsy. In order to localize these genes we will carry out a linkage and association study in the most extensive world-wide collection of DNAs from well-characterized patients with narcolepsy and their families.

  • Bonnie Halpern-Felsher

    Bonnie Halpern-Felsher

    Marron and Mary Elizabeth Kendrick Professor of Pediatrics and Professor, by courtesy, of Epidemiology and Population Health and of Psychiatry and Behavioral Sciences (Child and Adolescent Psychiatry)

    Current Research and Scholarly InterestsResearch focuses on developmental, cognitive and psychosocial factors involved in adolescents’ and young adults’ health-related decision-making, perceptions of risk and vulnerability, health communication and risk behavior. My research has focused on understanding and reducing health risk behaviors such as tobacco use, alcohol and marijuana use, risky driving, and risky sexual behavior.

  • Frank Hanley

    Frank Hanley

    Lawrence Crowley, M.D., Endowed Professor of Child Health

    Current Research and Scholarly InterestsHis research and clinical work focuses on the development of interventional techniques for fetal and neonatal treatment of congenital heart disease, pulmonary, vascular physiology, and the neurologic impact of open-heart surgery. He developed and pioneered the “unifocalization” procedure, in which a single procedure is used to repair a complex and life-threatening congenital heart defect rather than several staged open-heart surgeries as performed by other surgeons.

  • Maha Hanna

    Maha Hanna

    Clinical Assistant Professor, Pediatrics

    Current Research and Scholarly InterestsA bad latch means maternal excruciating pain, ineffective milk transfer with subsequent weight loss, hypoglycemia, higher risk of hyperbilirubinemia and dehydration fever.All of the above led to early cessation of breastfeeding; 46% of mothers who initiate exclusive breastfeeding stop within the first 12 weeks because of difficult latch. I developed a latch tutorial focusing on step-by step-in striations for achieving an effective, non-painful latch.

  • Antonio Hardan, M.D.

    Antonio Hardan, M.D.

    Professor of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsThe neurobiology of autism
    Neuroimaging in individuals with autism
    Psychopharmacological treatment of children and adults with autism and/or developmental disorders
    The neurobiology and innovative interventions of several neurogenic disorders including DiGeorge Syndrome (Velocardiofacial syndrome; 22q11.2 mutations), PTEN mutations, and Phelan McDermid Syndrome (22q13 mutations).

  • Keren Haroush

    Keren Haroush

    Assistant Professor of Neurobiology

    Current Research and Scholarly InterestsOur laboratory studies the mechanisms by which highly complex behaviors are mediated at the neuronal level, mainly focusing on the example of dynamic social interactions and the neural circuits that drive them. From dyadic interactions to group dynamics and collective decision making, the lab seeks a mechanistic understanding for the fundamental building blocks of societies, such as cooperation, empathy, fairness and reciprocity.

  • Phillip M. Harter, M.D.

    Phillip M. Harter, M.D.

    Associate Professor (Teaching) of Emergency Medicine, Emeritus

    Current Research and Scholarly InterestsMedical Education, particularly the role of simulation (part-task trainers, human patient simulators and virtual reality) in the education of medical students and residents. Also, the use of the internet for distance learning in health care professions.

  • Trevor Hastie

    Trevor Hastie

    John A. Overdeck Professor, Professor of Statistics and of Biomedical Data Sciences

    Current Research and Scholarly InterestsFlexible statistical modeling for prediction and representation of data arising in biology, medicine, science or industry. Statistical and machine learning tools have gained importance over the years. Part of Hastie's work has been to bridge the gap between traditional statistical methodology and the achievements made in machine learning.

  • Melanie Hayden Gephart

    Melanie Hayden Gephart

    Professor of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences

    BioI am a brain tumor neurosurgeon, treating patients with malignant and benign tumors, including gliomas, brain metastases, meningiomas, and schwannomas. I direct the Stanford Brain Tumor Center and the Stanford Brain Metastasis Consortium, collaborative unions of physicians and scientists looking to improve our understanding and treatment of brain tumors. My laboratory seeks greater understanding of the mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We study how rare cancer cell populations survive and migrate in the brain, inadvertently supported by native brain cells. We develop novel cerebrospinal fluid-based biomarkers to track brain cancer treatment response, relapse, and neurotoxicity. Our bedside-to-bench-to-bedside research model builds on a foundation of generously donated patient samples, where we test mechanisms of brain cancer growth, develop novel pre-clinical models that reliably recapitulate the human disease, and facilitate clinical trials of new treatments for patients with brain cancer.

    www.GephartLab.com
    www.GBMseq.org
    https://stan.md/BrainMets
    @HaydenGephartMD

  • John P. Hegarty II

    John P. Hegarty II

    Clinical Assistant Professor, Psychiatry and Behavioral Sciences

    BioI am a neuroscientist and Principal Investigator of the Stanford Clinical Neuroscience (CNS) Lab in the Department of Psychiatry and Behavioral Sciences as well as Director of Neuroimaging for the Autism and Developmental Disorders Research Program at Stanford. My innovative research studies clinical aspects of cognitive and behavioral neuroscience, with a special focus on examining the neural circuitry associated with important brain-behavior relationships that may underlie different psychological and psychiatric domains in autistic children, adolescents, and adults. The ultimate goal of this research is to improve our understanding of the development of different cognitive and behavioral skills in order to develop mechanistically driven interventions that will improve precision medicine for mental health. Biologically based diagnosis and treatment are extremely limited for most psychological and psychiatric conditions but also critically needed to increase early identification and improve treatment outcomes, especially for neurodevelopmental disorders in which early intervention is the most beneficial. My early career research has primarily focused on clinical neuroscience using neuroimaging (e.g., MRI & EEG) to examine the effects of different drugs and behavioral interventions on the brain, especially for developing biomarkers for improving treatment planning and monitoring biological changes in response to single dose and clinical trials.

    My primary contributions to science thus far fall within these major categories: 1) identifying the neural correlates of individual differences in cognition and behavior, 2) developing new interventions and investigating the neurobiological substrates of response to treatment, 3) examining different factors that contribute to brain development, 4) summarizing and increasing accessibility to autism-related research, and 5) methods development for neuroimaging studies. My earliest research investigated the neurobiology of alexithymia, dyslexia, and stress using structural and functional magnetic resonance imaging to test theories of the mechanisms that contribute to differences in cognition and behavior. My subsequent dissertation research, in which I began to focus on neurodevelopmental disorders, examined the neural correlates of response to beta-blockers in autistic adults and also assessed the contribution of cerebellar circuits to the autism phenotype. During my postdoctoral training, I have developed further skills for working with children in multiple clinical research settings, especially for using advanced neuroimaging approaches to examine important brain-behavior relationships. This includes a recent K99/R00 from the National Institute of Child Health and Human Development (NCT04278898 & NCT05664789) that will assess the neurobiology of restricted and repetitive behaviors in autistic children and examine the efficacy and target engagement of a novel nutritional supplement and investigational drug, N-acetylcysteine (NAC), in the brain. You can find more information about our NAC studies at https://redcap.link/NACandAutism.

  • Wm. LeRoy Heinrichs

    Wm. LeRoy Heinrichs

    Member, Maternal & Child Health Research Institute (MCHRI)

    Current Research and Scholarly InterestsSurgical simulation; team-training in virtual environments; online training of healthcare providers in virtual environments; tele-medicine for acute & chronic disease management in virtual environments

  • Stefan Heller

    Stefan Heller

    Edward C. and Amy H. Sewall Professor in the School of Medicine and Professor of Otolaryngology - Head & Neck Surgery (OHNS)
    On Partial Leave from 09/01/2024 To 02/28/2025

    Current Research and Scholarly InterestsOur research focuses on the inner ear, from its earliest manifestation as one of the cranial placodes until it has developed into a mature and functioning organ. We are interested in how the sensory epithelia of the inner ear that harbor the sensory hair cells develop, how the cells mature, and how these epithelia respond to toxic insults. The overarching goal of this research is to find ways to regenerate lost sensory hair cells in mammals.

  • Rachel E. Herdes

    Rachel E. Herdes

    Clinical Assistant Professor, Pediatrics - Gastroenterology

    Current Research and Scholarly InterestsAs a pediatric physician-investigator, I strive to understand the role of nutrition and diet therapy in pediatric health. I am particularly interested in understanding and developing novel treatment plans for adolescent patients with obesity and in establishing guidelines to improve health outcomes for pediatric intestinal failure patients.

    Current research studies include novel treatment options for pediatric metabolic dysfunction-associated steatotic liver disease (MASLD), health equity in pediatric patients with intestinal failure, and medication management after metabolic and bariatric surgery in pediatric patients with severe obesity.

  • Tina Hernandez-Boussard

    Tina Hernandez-Boussard

    Professor of Medicine (Biomedical Informatics), of Biomedical Data Science, of Surgery and, by courtesy, of Epidemiology and Population Health

    Current Research and Scholarly InterestsMy background and expertise is in the field of computational biology, with concentration in health services research. A key focus of my research is to apply novel methods and tools to large clinical datasets for hypothesis generation, comparative effectiveness research, and the evaluation of quality healthcare delivery. My research involves managing and manipulating big data, which range from administrative claims data to electronic health records, and applying novel biostatistical techniques to innovatively assess clinical and policy related research questions at the population level. This research enables us to create formal, statistically rigid, evaluations of healthcare data using unique combinations of large datasets.

  • Lynn Hildemann

    Lynn Hildemann

    Wayne Loel Professor of Sustainability and Senior Associate Dean for Education

    BioLynn Hildemann's current research areas include the sources and dispersion of airborne particulate matter indoors, and assessment of human exposure to air pollutants.

    Prof. Hildemann received BS, MS, and PhD degrees in environmental engineering science from the California Institute of Technology. She is an author on >100 peer-reviewed publications, including two with over 1000 citations each, and another 6 with over 500 citations each. She has been honored with Young Investigator Awards from NSF and ONR, the Kenneth T. Whitby Award from the AAAR (1998), and Stanford's Gores Award for Teaching Excellence (2013); she also was a co-recipient of Atmospheric Environment’s Haagen-Smit Outstanding Paper Award (2001).

    She has served on advisory committees for the Bay Area Air Quality Management District and for the California Air Resources Board. She has been an Associate Editor for Environmental Science & Technology, and Aerosol Science and Technology, and has served on the advisory board for the journal Environmental Science & Technology.

    At Stanford, Prof. Hildemann has been chair of the Department of Civil & Environmental Engineering, and served as an elected member of the Faculty Senate. She has chaired the School of Engineering Library Committee, the University Committee on Judicial Affairs, and the University Breadth Governance Board.

  • Susan R. Hintz, M.D., M.S. Epi.

    Susan R. Hintz, M.D., M.S. Epi.

    Robert L. Hess Family Professor and Professor, by courtesy, of Obstetrics and Gynecology

    Current Research and Scholarly Interests1) Early childhood neurodevelopmental outcomes, mortality and morbidities of extremely premature and high-risk infants
    2) Use of advanced neuroimaging and other predictors of neurodevelopmental outcomes in high-risk infants, evidence-based interventions to improve outcomes
    3) Quality and process improvement throughout the continuum of care
    4) Natural history and outcomes of complex fetal anomalies, implementing innovative fetal therapies.

  • Andrew R. Hoffman

    Andrew R. Hoffman

    Professor of Medicine (Endocrinology), Emeritus

    Current Research and Scholarly InterestsMechanism of genomic imprinting of insulin like growth factor-2 and other genes.Long range chromatin interactions Role of histone modifications and DNA methylation in gene expression.

  • Marie Hollenhorst, MD, PhD

    Marie Hollenhorst, MD, PhD

    Basic Life Research Scientist, Sarafan ChEM-H

    BioDr. Hollenhorst is a physician and scientist with expertise in non-malignant hematology, transfusion medicine, and chemical biology. Dr. Hollenhorst values the one-on-one relationships that she forms with her patients, and strives to deliver the highest quality of care for individuals with blood diseases. Her experience caring for patients drives her to ask scientific questions in the laboratory, where she aims to bring a chemical approach to the study of non-malignant blood disease.

    Dr. Hollenhorst pursued combined MD and PhD training at Harvard University, where she received a PhD in Chemical Biology under the mentorship of Professor Christopher T Walsh. She subsequently completed a residency in Internal Medicine at Brigham and Women's Hospital, a fellowship in Transfusion Medicine at Harvard Medical School, and a fellowship in Hematology at Stanford.

    Dr. Hollenhorst has an interest in the biology of platelets, which are cellular fragments that help the blood to maintain a healthy balance between bleeding and clotting. Working in the laboratory of Professor Carolyn Bertozzi of Stanford Chemistry, Dr. Hollenhorst is studying sugar molecules found on the surface of platelets that are important in controlling their function and lifespan.

    Dr. Hollenhorst's research is supported by an NIH K99 Career Pathway to Independence in Blood Science Award for Physician-Scientists, a Stanford Chemistry, Engineering & Medicine for Human Health Physician-Scientist Fellowship, and a National Blood Foundation Early-Career Scientific Research Grant.

  • Susan Holmes

    Susan Holmes

    Professor of Statistics, Emerita

    Current Research and Scholarly InterestsOur lab has been developing tools for the analyses of complex data structures, extending work on multivariate data to structured multitable table that include graphs, networks and trees as well as categorical and continuous measurements.
    We created and support the Bioconductor package phyloseq for the analyses of microbial ecology data from the microbiome. We have specialized in developing interactive graphical visualization tools for doing reproducible research in biology.

  • David Hong

    David Hong

    Member, Maternal & Child Health Research Institute (MCHRI)

    BioDr. Hong specializes in the treatment of pediatric patients with neurosurgical conditions, with additional specialty training in the treatment of pediatric spinal disorders, including scoliosis. He completed his residency in his home state of Michigan at the Detroit Medical Center, and completed fellowship training at Rady Children's Hospital in San Diego, before becoming a part of Stanford Children's Health.

    His clinical interests include brain tumors, epilepsy surgery, idiopathic scoliosis, Chiari malformation, vascular conditions, concussion, and will treat all other conditions within the specialty.

  • David S. Hong

    David S. Hong

    Associate Professor of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)

    Current Research and Scholarly InterestsDr. Hong is a child and adolescent psychiatrist and clinician-scientist. His responsibilities span clinical care, teaching/mentorship, and research, with a unifying theme of advancing a developmental cognitive framework as applied to psychiatric conditions. Using this core premise, he work encompasses multiple domains: specialized clinical care, fellowship training, research mentorship, and elaborating the role of sex-specific determinants of development, one of the greatest contributors to individual developmental variation.

    His lab investigates genetic and hormonal influences underlying sex differences in child psychiatric conditions. Sex has emerged as a critical variable driving differences in the phenomenology, course, and treatment of many mental health disorders. Unfortunately, an understanding of the biological mechanisms driving these effects are limited. By applying innovative neuroimaging and multiomic approaches, Dr. Hong seeks to provide a deeper understanding of the connection between sex-specific effects and complex psychiatric diseases. To do so, research in the Hong Lab focuses on the role of genes on the X and Y chromosomes, as well as circulating sex hormones on brain development, cognition, and behavior. The lab broadly aims to elucidate the changing nature of these mechanisms across various stages of development.

    Another area of focus is the implementation of clinical informatics in child psychiatry and the development of digital mental health tools. As co-Director of the Mental Health Technology and Innovation Hub, Dr. Hong is helping to develop clinical and research infrastructure within the Department of Psychiatry and Behavioral Sciences to advance development of mobile mental health resources that will improve efficacy and access to mental health care.

  • Anita Honkanen

    Anita Honkanen

    Clinical Professor, Anesthesiology, Perioperative and Pain Medicine

    Current Research and Scholarly InterestsPatient Safety and Simulation
    Effective Use of Health Care Resources

  • Korey Hood

    Korey Hood

    Professor of Pediatrics (Endocrinology) and of Psychiatry and Behavioral Sciences (Child and Adolescent Psychiatry and Child Development)

    BioKorey Hood, PhD is personally and professionally committed to improving the lives of people with diabetes. As Professor and Staff Psychologist at Stanford University School of Medicine, Dr. Hood runs a behavioral science laboratory aimed at optimizing health and quality of life outcomes. A recipient of federal and foundation grants and author of over 200 scientific articles, Dr. Hood works to put behavioral science at the forefront of patient-centered diabetes care. Dr. Hood has type 1 diabetes himself and works across advocacy and service settings to promote awareness of diabetes treatments, the psychological impact, and emerging technologies. Dr. Hood is a compassionate behavioral scientist with a keen understanding of the intersection between diabetes and behavioral health.

  • Rachel Knight Hopper

    Rachel Knight Hopper

    Clinical Professor, Pediatrics - Cardiology

    Current Research and Scholarly InterestsCurrent research interests include:
    PH related to prematurity and bronchopulmonary dysplasia
    Right heart failure in children with pulmonary hypertension, imaging and biomarkers
    Pulmonary hypertension in children with congenital heart disease and/or heart failure
    Clinical trials in children with PH

  • Audra Horomanski

    Audra Horomanski

    Clinical Assistant Professor, Medicine - Immunology & Rheumatology

    BioDr. Horomanski specializes in the diagnosis and treatment of rheumatologic diseases. She received her undergraduate degree from Case Western Reserve University, medical degree from Wright State University, and completed her Internal Medicine residency and Rheumatology fellowship at Stanford University. She is the Director of the Stanford Vasculitis Clinic where she manages the complex care of patients with all types of vasculitis and works closely with partners in related specialties. She has a specific interest in clinical trials and a Graduate Certificate in Epidemiology and Clinical Research. Dr. Horomanski also received training in musculoskeletal ultrasound from the USSONAR program and is an integral part of Stanford's Diagnostic and Interventional Musculoskeletal Ultrasound Clinic. Additional areas of research include the application of ultrasound in the study and management of rheumatologic diseases.

  • Machiko Hosoki

    Machiko Hosoki

    Clinical Assistant Professor, Pediatrics

    Current Research and Scholarly InterestsReading problem in bilingual children in elementary school

  • Hadi Hosseini

    Hadi Hosseini

    Associate Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)

    Current Research and Scholarly InterestsOur lab’s research portfolio crosses multiple disciplines including computational neuropsychiatry, cognitive neuroscience, multimodal neuroimaging and neurocognitive rehabilitation. Our computational neuropsychiatry research mainly involves investigating alterations in the organization of connectome in various neurodevelopmental and neurocognitive disorders using state of the art neuroimaging techniques (fMRI, sMRI, DWI, functional NIRS) combined with novel computational methods (graph theoretical and multivariate pattern analyses).

    The ultimate goal of our research is to translate the findings from computational neuropsychiatry research toward developing personalized interventions. We have been developing personalized interventions that integrate computerized cognitive rehabilitation, real-time functional brain imaging and neurofeedback, as well as virtual reality (VR) tailored toward targeted rehabilitation of the affected brain networks in patients with neurocognitive disorders.

  • Brooke Howitt

    Brooke Howitt

    Associate Professor of Pathology

    BioDr. Howitt is a gynecologic and sarcoma pathologist, with academic interests in gynecologic mesenchymal tumors and morphologic and clinical correlates of molecular alterations in gynecologic neoplasia.

  • Michael R. Howitt

    Michael R. Howitt

    Assistant Professor of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsOur lab is broadly interested in how intestinal microbes shape our immune system to promote both health and disease. Recently we discovered that a type of intestinal epithelial cell, called tuft cells, act as sentinels stationed along the lining of the gut. Tuft cells respond to microbes, including parasites, to initiate type 2 immunity, remodel the epithelium, and alter gut physiology. Surprisingly, these changes to the intestine rely on the same chemosensory pathway found in oral taste cells. Currently, we aim to 1) elucidate the role of specific tuft cell receptors in microbial detection. 2) To understand how protozoa and bacteria within the microbiota impact host immunity. 3) Discover how tuft cells modulate surrounding cells and tissue.

  • Deborah Hsu, MD, MEd

    Deborah Hsu, MD, MEd

    Professor of Emergency Medicine (Pediatrics) and, by courtesy, of Pediatrics (Hospital Medicine)

    Current Research and Scholarly InterestsCompetency-based medical education; assessment; curriculum development; professional development

    Recent projects:
    American Board of Pediatrics EPA to Milestone Navigator Pediatric Emergency Medicine Work Group leader. Mapping pediatric emergency medicine milestones 2.0 to pediatric emergency medicine and common pediatric subspecialty entrustable professional activities. March 2024. Access at https://public.tableau.com/app/profile/americanboardofpediatrics/viz/EPAtoMilestoneCrosswalk/PrimaryDashboard?publish=yes

    Pediatric Emergency Medicine Milestones Work Group member. Pediatric Emergency Medicine Milestones. The Accreditation Council for Graduate Medical Education. April 2022. Access at https://www.acgme.org/globalassets/pdfs/milestones/pediatricemergencymedicinemilestones.pdf

    Pediatric Emergency Medicine Milestones Work Group member. Supplemental Guide: Pediatric Emergency Medicine. The Accreditation Council for Graduate Medical Education. April 2022. Access at https://www.acgme.org/globalassets/pdfs/milestones/pediatricemergencymedicinesupplementalguide.pdf

    Hsu D, Aye T, Carraccio C, Goodman D, Johnson T, and Ryan S. EPAs that are common to all subspecialties: Lead within the subspecialty profession. American Board of Pediatrics Information for Program Directors. April 2017. Access at https://www.abp.org/content/entrustable-professional-activities-subspecialties

    Hsu D, Nypaver M, et al. Subspecialty-Specific EPAs: Pediatric Emergency Medicine Entrustable Professional Activities. American Board of Pediatrics Information for Program Directors. March 2016. Access at https://www.abp.org/content/entrustable-professional-activities-subspecialties

  • Joe Le Hsu

    Joe Le Hsu

    Assistant Professor of Medicine (Pulmonary and Critical Care)

    Current Research and Scholarly InterestsI am interested in understanding the host-pathogen interaction between Aspergillus fumigatus and the lung transplant recipient.

  • Joyce Hsu

    Joyce Hsu

    Clinical Associate Professor, Pediatrics - Rheumatology

    Current Research and Scholarly InterestsPediatric Systemic Lupus Erythematosus;

    Lupus Nephritis;

    Racial/Ethnic Differences in Pediatric Lupus Patients

    CARRA Registry

  • Aaron Hsueh

    Aaron Hsueh

    Professor of Obstetrics and Gynecology (Reproductive and Stem Cell Biology), Emeritus

    Current Research and Scholarly InterestsHormonal regulation of ovarian function; gonadotropin receptors and related genes, bioinformatic ananlyses of polypeptide hormones and receptors, follicle recruitment and GDF-9; analysis of oocyte and ovarian-expressed genes.

  • Ngan F. Huang

    Ngan F. Huang

    Associate Professor of Cardiothoracic Surgery (Cardiothoracic Surgery Research) and, by courtesy, of Chemical Engineering

    Current Research and Scholarly InterestsDr. Huang's laboratory aims to understand the chemical and mechanical interactions between extracellular matrix (ECM) proteins and pluripotent stem cells that regulate vascular and myogenic differentiation. The fundamental insights of cell-matrix interactions are applied towards stem cell-based therapies with respect to improving cell survival and regenerative capacity, as well as engineered vascularized tissues for therapeutic transplantation.

  • Lynne C. Huffman

    Lynne C. Huffman

    Professor (Teaching) of Pediatrics (Developmental-Behavioral Pediatrics) and, by courtesy, of Psychiatry and Behavioral Sciences
    On Partial Leave from 02/01/2024 To 08/31/2025

    Current Research and Scholarly InterestsResearch interests and activities include (1) shared decision-making in clinical care; (2) medical education research; (3) the early identification and treatment of behavioral problems, particularly in children with special health care needs; and (4) community-based mental health/educational program evaluation and outcomes measurement.

  • John Huguenard

    John Huguenard

    Professor of Neurology and Neurological Sciences (Neurology Research), of Neurosurgery (Adult Neurosurgery) and, by courtesy, of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsWe are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.