School of Medicine
Showing 21-40 of 336 Results
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Maria Barna
Associate Professor of Genetics
Current Research and Scholarly InterestsOur lab studies how intricate control of gene expression and cell signaling is regulated on a minute-by-minute basis to give rise to the remarkable diversity of cell types and tissue morphology that form the living blueprints of developing organisms. Work in the Barna lab is presently split into two main research efforts. The first is investigating ribosome-mediated control of gene expression genome-wide in space and time during cellular differentiation and organismal development. This research is opening a new field of study in which we apply sophisticated mass spectrometry, computational biology, genomics, and developmental genetics, to characterize a ribosome code to gene expression. Our research has shown that not all of the millions of ribosomes within a cell are the same and that ribosome heterogeneity can diversify how genomes are translated into proteomes. In particular, we seek to address whether fundamental aspects of gene regulation are controlled by ribosomes harboring a unique activity or composition that are tuned to translating specific transcripts by virtue of RNA regulatory elements embedded within their 5’UTRs. The second research effort is centered on employing state-of-the-art live cell imaging to visualize cell signaling and cellular control of organogenesis. This research has led to the realization of a novel means of cell-cell communication dependent on a dense network of actin-based cellular extension within developing organs that interconnect and facilitate the precise transmission of molecular information between cells. We apply and create bioengineering tools to manipulate such cellular interactions and signaling in-vivo.
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Greg Barsh
Professor of Genetics and of Pediatrics, Emeritus
Current Research and Scholarly InterestsGenetics of color variation
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Michael Bassik
Associate Professor of Genetics
Current Research and Scholarly InterestsWe are an interdisciplinary lab focused on two major areas:(1) we seek to understand mechanisms of cancer growth and drug resistance in order to find new therapeutic targets(2) we study mechanisms by which macrophages and other cells take up diverse materials by endocytosis and phagocytosis; these substrates range from bacteria, viruses, and cancer cells to drugs and protein toxins. To accomplish these goals, we develop and use new technologies for high-throughput functional genomics.
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Anne Brunet
Michele and Timothy Barakett Endowed Professor
Current Research and Scholarly InterestsWe want to understand aging based on the integration of model organisms with diverse lifespans. We have identified pathways involved in delaying aging in response to external stimuli such as availability of nutrients. We are also interested in addressing complex questions about aging in vertebrates, focusing on brain aging and rejuvenation. Finally, we have pioneered the short-lived African killifish as a powerful model to identify new principles of vertebrate aging and ‘suspended animation’.
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Mai Ly Tran Burke
Masters Student in Human Genetics and Genetic Counseling, admitted Autumn 2024
BioI am Mai Ly Burke, a Master's student in Human Genetics and Genetic Counseling. Having grown up in Vietnam—a country that grapples with many health challenges—my work is fueled by a genuine passion for giving back to my community. I was inspired to enter the genetic counseling field by my volunteer work supporting children with cancer in public hospitals in Vietnam, where I saw the urgent need for improved access to healthcare. My goal is to facilitate the introduction of the genetic counseling field to Vietnam, where there is a stark shortage of genetic experts, to improve health outcomes in my community.
Please feel free to reach out to connect! I always want to meet others who share my passion for genetics, global health, and health equity. -
Sonia Bustos
Ph.D. Student in Genetics, admitted Summer 2022
OTL Intern, Office of Technology Licensing (OTL)Current Role at StanfordGraduate student in the Genetics Department