School of Medicine
Showing 8,781-8,800 of 12,898 Results
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Trung Hoang Minh Pham
Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsUncovering mechanisms of tissue immunity and immunophysiology during persistent infection
The immune system safeguards the health of complex organisms by rapidly eliminating invading pathogens, curbing infection-induced tissue disruptions, and maintaining tissue homeostasis. Many bacterial pathogens evade host antimicrobial mechanisms and persist in infected tissues at low levels for long periods of time even in the presence of innate and adaptive immune resistance. During persistent infection, the immune system simultaneously orchestrates antimicrobial responses to contain the pathogen, repairs damaged tissue, regulates nutrient resources, and maintains other tissue physiological functions to ensure host survival. Failure of any of these tasks leads to uncontrolled infection, devastating disease, and even death. The goals of our research are to understand:
1)What are the innate and adaptive immune cellular mechanisms that contain pathogens during persistent infection?
2)How are tissue physiological functions, such as tissue repair and nutrient regulation, maintained during persistent infection?
3)How do pathogens survive innate and adaptive antimicrobial mechanisms in infected tissues?
4)How does persistent infection impact host immunity to secondary infections of a similar or different pathogen?
Through investigating these fundamental questions, we may be able to decode the underlying cellular and molecular mechanisms that can be harnessed to eradicate infections, promote tissue resilience, and restore health after an infectious insult. We integrate immunology, tissue biology, microbiology, and genetics to uncover the mechanisms of tissue immunity and immunophysiology during persistent infection from the molecular to organismal level.
Current areas of research:
•Development, maintenance, and plasticity of macrophage functional diversity in infected tissue
•Tissue repair and nutrient regulation during persistent infection
•Cellular dynamics and bacterial persistence in lymphoid organs -
Harold Westley Phillips
Assistant Professor of Neurosurgery (Pediatric Neurosurgery)
BioH. Westley Phillips, MD is an Assistant Professor of Neurosurgery at Stanford University where he is a neurosurgeon-scientist specializing in pediatric neurosurgery with a special interest in epilepsy. Dr. Phillips received his undergraduate degree at Yale University where he was a member of the Varsity Football Team and received a Fulbright Scholarship. He completed an MD at the Perelman School of Medicine at the University of Pennsylvania, graduating with a certificate of distinction in the Clinical Neuroscience Training Program. He completed neurosurgical residency at UCLA where he received 2 years of NIH funding to investigate the genetic underpinnings of epilepsy. He received fellowship training in pediatric epilepsy surgery and genetics research at Boston Children’s Hospital as well as pediatric neurosurgery at the University of Pittsburgh Medical Center, Children’s Hospital of Pittsburgh before his arrival at Stanford. At Stanford, Dr. Phillips leads a molecular genetics laboratory and has a particular interest in defining and further understanding somatic mosaicism and its role in epileptogenesis. He has published manuscripts in leading academic journals including Nature: Genetics, JAMA Neurology, Journal of Neuroscience, Scientific Reports, Epilepsia and Neurology. He is dedicated to improving the treatment and outcomes for children with drug resistant epilepsy through innovative research and cutting-edge surgical techniques.
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Jennifer M. Phillips, PhD
Clinical Professor, Psychiatry and Behavioral Sciences - Child & Adolescent Psychiatry and Child Development
Current Research and Scholarly InterestsAutism spectrum disorders, young child assessment, developmental disabilities
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Ashley Phoenix
Postdoctoral Scholar, Anesthesiology, Perioperative and Pain Medicine
BioDr. Ashley Phoenix earned her B.S. in Biological Sciences from the College of Charleston, where her passion for neuroscience first took root through undergraduate research on drug seeking behavior at the Medical University of South Carolina. She went on to complete an M.S. in Biomedical Sciences at the University of Alabama at Birmingham, strengthening her scientific foundation before earning her M.D. at Wake Forest University School of Medicine.
Her research career has spanned diverse yet interconnected realms of neuroscience — from investigating post-stroke cognitive decline at MUSC, to exploring the neurodevelopmental basis of disorders such as Rett syndrome at the NIH National Institute of Environmental Health Sciences, to contributing to neurosurgery research at Wake Forest with a focus on cognition and perioperative outcomes.
Now, as a Postdoctoral Research Fellow in the Neuroanesthesia Laboratory of Dr. Miles Berger at Stanford, Dr. Phoenix is uniting her lifelong fascination with the brain and cognitive decline, and her future clinical practice in anesthesiology. Her current work focuses on elucidating the mechanisms behind — and developing early detection strategies for — postoperative delirium in the elderly surgical population.
Through this fellowship, Dr. Phoenix is building the foundation for her career as a physician-scientist, committed to advancing patient care while pursuing research that safeguards cognitive health in the perioperative setting. -
Tanmoy Sarkar Pias
Postdoctoral Scholar, Urology
BioI am currently working on multimodal, multi-task foundation models to detect cancer and improve surgery. I am exploring image segmentation models, foundation models, and reinforcement learning with agents. My previous work spans a range of directions, including knowledge-guided machine learning models, systematic evaluation of high-risk models, mitigation of deficiencies and biases, automatic generation of gradient-based test cases, decision boundary estimation and analysis of deep learning models, and developing approaches to make machine learning models more fair and reliable.
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Andrew Picel, MD
Clinical Associate Professor, Radiology
Current Research and Scholarly InterestsProstate artery embolization (PAE) for the treatment of lower urinary tract symptoms (LUTS) from benign prostatic hyperplasia (BPH).
Prophylactic balloon occlusion catheters and uterine artery embolization to reduce blood loss in patients with invasive placenta.
Geniculate artery embolization for relief of osteoarthritis related knee pain.
