School of Medicine
Showing 8,821-8,840 of 12,989 Results
-
Edward A. Pham
Instructor, Medicine - Gastroenterology & Hepatology
BioMy interest in medicine and research was triggered by my mother’s battle with chronic hepatitis C, which made me realize the transformational power of biomedical research in treating patients. Therefore, my career goal is to become a physician scientist in the field of gastroenterology and hepatology dedicated to translating discoveries in the laboratory into novel medical treatment modalities. My research focus is alterations in phosphoinositides signaling and its pathogenesis in cancers of the hepatobiliary and luminal GI tract with the goal to identify novel targets for therapeutic intervention. I also have a particular interest in understanding the interface between chronic viral infection and cancer through studying how the innate and adaptive immune system are perturbed in chronic viral infections
-
Hang T Pham
Research Specialist, Surgery - General Surgery
Current Role at StanfordStanford School of Medicine: Senior Research Scientist
Stanford Prevention Policy Modeling Lab: Affiliated Member (https://ppml.stanford.edu/people/hang-pham) -
Rachel Pham
Educational Program Manager, Epidemiology and Population Health
Current Role at StanfordEducational Program Manager
-
Tho Duc Pham
Clinical Professor, Pathology
Current Research and Scholarly InterestsMy areas of interest involve exploring antibody function as it relates to transfusion medicine, blood safety, and emerging infectious diseases. This ranges from natural immune responses to the ABO blood group, antibody profiling anti-SARS-CoV-2 antibodies, and studying HEV seroprevalence in the local community. I am also interested in exploring statistical approaches to improve blood product availability and overall health care efficiency in a tertiary care system.
-
Trung Hoang Minh Pham
Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsUncovering mechanisms of tissue immunity and immunophysiology during persistent infection
The immune system safeguards the health of complex organisms by rapidly eliminating invading pathogens, curbing infection-induced tissue disruptions, and maintaining tissue homeostasis. Many bacterial pathogens evade host antimicrobial mechanisms and persist in infected tissues at low levels for long periods of time even in the presence of innate and adaptive immune resistance. During persistent infection, the immune system simultaneously orchestrates antimicrobial responses to contain the pathogen, repairs damaged tissue, regulates nutrient resources, and maintains other tissue physiological functions to ensure host survival. Failure of any of these tasks leads to uncontrolled infection, devastating disease, and even death. The goals of our research are to understand:
1)What are the innate and adaptive immune cellular mechanisms that contain pathogens during persistent infection?
2)How are tissue physiological functions, such as tissue repair and nutrient regulation, maintained during persistent infection?
3)How do pathogens survive innate and adaptive antimicrobial mechanisms in infected tissues?
4)How does persistent infection impact host immunity to secondary infections of a similar or different pathogen?
Through investigating these fundamental questions, we may be able to decode the underlying cellular and molecular mechanisms that can be harnessed to eradicate infections, promote tissue resilience, and restore health after an infectious insult. We integrate immunology, tissue biology, microbiology, and genetics to uncover the mechanisms of tissue immunity and immunophysiology during persistent infection from the molecular to organismal level.
Current areas of research:
•Development, maintenance, and plasticity of macrophage functional diversity in infected tissue
•Tissue repair and nutrient regulation during persistent infection
•Cellular dynamics and bacterial persistence in lymphoid organs
