School of Medicine
Showing 21-40 of 91 Results
-
Antonina Hafner
Postdoctoral Scholar, Developmental Biology
BioI am a postdoctoral fellow in the lab of Alistair Boettiger in the Department of Developmental Biology. I have always been interested in understanding regulatory mechanisms that lead to tissue or cell type specific gene expression. During my PhD in the lab of Galit Lahav at Harvard Medical School, I studied how temporal dynamics of a tumor suppressor transcription factor, p53 regulate the dynamics of gene expression in response to DNA damage. In the Boettiger lab, I'm interested how specificity between enhancer-promoter interactions is achieved using super-resolution microscopy.
-
Daniel Jarosz
Associate Professor of Chemical and Systems Biology and of Developmental Biology
Current Research and Scholarly InterestsMy laboratory studies conformational switches in evolution, disease, and development. We focus on how molecular chaperones, proteins that help other biomolecules to fold, affect the phenotypic output of genetic variation. To do so we combine classical biochemistry and genetics with systems-level approaches. Ultimately we seek to understand how homeostatic mechanisms influence the acquisition of biological novelty and identify means of manipulating them for therapeutic and biosynthetic benefit.
-
Seung K. Kim M.D., Ph.D.
KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
Current Research and Scholarly InterestsWe study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.
-
Stuart Kim
Professor of Developmental Biology, Emeritus
Current Research and Scholarly InterestsMechanisms of Aging in C. elegans and humans.
-
David Kingsley
Rudy J. and Daphne Donohue Munzer Professor in the School of Medicine
Current Research and Scholarly InterestsWe use mice, stickleback fish, and humans to study the molecular basis of evolution and common diseases. By combining genetics and genomics, we have identified key DNA changes that control bone formation, limb patterning, hair color, brain evolution, and susceptibility to arthritis, schizophrenia, and bipolar disorder. We find that the same genetic mechanisms are often used repeatedly in nature, providing new insights into the origin of key traits in many different species, including ourselves.
