School of Medicine
Showing 801-810 of 1,201 Results
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Heather Ryan Pankow
Life Science Rsch Prof 2, Psych/General Psychiatry and Psychology (Adult)
Current Role at StanfordLife Science Research Professional 2 in The Depression Research Clinic
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Sara Pardej
Postdoctoral Scholar, Psychiatry
BioSara Pardej earned her BA in Psychology and BS in Cognitive Science at Marquette University. Afterwards, she attended the Clinical Psychology Doctoral Program at the University of Wisconsin-Milwaukee under the mentorship of Dr. Bonita P. Klein-Tasman, where she earned both her MS and PhD in Clinical Psychology. There, she worked on several studies focusing on youth with neurofibromatosis type 1 (NF1), including behavioral phenotyping work, psychometric studies, and a social skills intervention study. Her dissertation study, which was funded by a Young Investigator Award from the Children's Tumor Foundation, focused on examining event related potentials using EEG by comparing children with NF1 to children with idiopathic ADHD and unaffected children. She completed her Doctoral Internship in Clinical Psychology at Penn State Health in Hershey, Pennsylvania. While at Penn State, she also worked on research examining safety and psychopathology in youth with ADHD and/or autism. Her clinical interest is neuropsychology, and her research interests include issues of psychometrics, behavioral phenotyping, and the neuropsychological development (and subsequent areas of intervention) of individuals with NF1 across the lifespan.
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Karen J. Parker, PhD
Truong-Tan Broadcom Endowed Professor and Professor, by courtesy, of Comparative Medicine
Current Research and Scholarly InterestsThe Parker Lab conducts research on the biology of social functioning in monkeys, typically developing humans, and patients with social difficulties.
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Akshay Paruchuri
Postdoctoral Scholar, Psychiatry
BioI'm currently a postdoctoral scholar in the Stanford Translational AI (STAI) lab led by Professor Ehsan Adeli. I earned my PhD in computer science at UNC Chapel Hill under the advisement of Professor Henry Fuchs. My research interests are at the intersection of health AI, computer vision, and machine learning. Currently, I'm working toward a future where next-generation healthcare systems improve the entire patient journey, from advanced diagnostic imaging and surgical support to all-day health monitoring and management, to achieve better therapeutic outcomes for cancer and aging-related diseases. I'm generally interested in opportunities that would allow me to continue to deepen my research expertise while leading and working on projects with meaningful, positive real-world impact, especially with respect to areas such as healthcare and environmental sustainability.
Previously, I was a visiting researcher at IDSIA USI-SUPSI working with Professor Piotr Didyk on the interpretability of multimodal language models (MLMs) with respect to capabilities such as visual perception. I've published in leading venues on topics such as remote health sensing (WACV, NeurIPS), 3D reconstruction (ECCV, MICCAI), LLM-based conversational agents for personal health (EMNLP, Nature Communications), and energy-efficient operation of smart glasses (ISMAR). I've done internships at Google AR/VR, Google Consumer Health Research, and Kitware. -
Sergiu P. Pasca
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences and Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program
Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
To address this, we are developing bottom-up approaches to generate and assemble, from multi-cellular components, human neural circuits in vitro and in vivo.
We introduced the use of instructive signals for deriving from human pluripotent stem cells self-organizing 3D cellular structures named brain region-specific spheroids/organoids. We demonstrated that these cultures, such as the ones resembling the cerebral cortex, can be reliably derived across many lines and experiments, contain synaptically connected neurons and non-reactive astrocytes, and can be used to gain mechanistic insights into genetic and environmental brain disorders. Moreover, when maintained as long-term cultures, they recapitulate an intrinsic program of maturation that progresses towards postnatal stages.
We also pioneered a modular system to integrate 3D brain region-specific organoids and study human neuronal migration and neural circuit formation in functional preparations that we named assembloids. We have actively applied these models in combination with studies in long-term ex vivo brain preparations to acquire a deeper understanding of human physiology, evolution and disease mechanisms.
We have carved a unique research program that combines rigorous in vivo and in vitro neuroscience, stem cell and molecular biology approaches to construct and deconstruct previously inaccessible stages of human brain development and function in health and disease.
We believe science is a community effort, and accordingly, we have been advancing the field by broadly and openly sharing our technologies with numerous laboratories around the world and organizing the primary research conference and the training courses in the area of cellular models of the human brain.
