Stanford University
Showing 61-80 of 250 Results
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Josef Parvizi, MD, PhD
Professor of Neurology (Adult Neurology) and, by courtesy, of Neurosurgery
BioDr. Parvizi completed his medical internship at Mayo Clinic, neurology training at Harvard, and subspecialty training in clinical neurophysiology and epilepsy at UCLA before joining the Department of Neurology and Neurological Sciences at Stanford in 2007. Dr. Parvizi directs the Stanford Program for Medication Resistant Epilepsies and specializes in surgical treatments of intractable focal epilepsies. Dr. Parvizi is the principal investigator in the Laboratory of Behavioral and Cognitive Neuroscience, where he leads a team of investigators to study the human brain. http://med.stanford.edu/parvizi-lab.html.
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Anca M. Pasca, MD
Assistant Professor of Pediatrics
Current Research and Scholarly InterestsThe research focus of the lab is to understand molecular mechanisms underlying neurodevelopmental disorders associated with premature birth, neonatal and fetal brain injury with the long-term goal of translating the lab’s findings into therapeutics. The research team employs a multidisciplinary approach involving genetics, molecular and developmental neurobiology, animal models and neural cells differentiated from patient-derived induced pluripotent stem (iPS) cells. In particular, the lab is using a powerful 3D human brain-region specific organoid system developed at Stanford (Nature Methods, 2015; Nature Protocols, 2018) to ask questions about brain injury during development.
https://www.neopascalab.org/ -
Sergiu P. Pasca
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences and Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program
Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
To address this, we are developing bottom-up approaches to generate and assemble, from multi-cellular components, human neural circuits in vitro and in vivo.
We introduced the use of instructive signals for deriving from human pluripotent stem cells self-organizing 3D cellular structures named brain region-specific spheroids/organoids. We demonstrated that these cultures, such as the ones resembling the cerebral cortex, can be reliably derived across many lines and experiments, contain synaptically connected neurons and non-reactive astrocytes, and can be used to gain mechanistic insights into genetic and environmental brain disorders. Moreover, when maintained as long-term cultures, they recapitulate an intrinsic program of maturation that progresses towards postnatal stages.
We also pioneered a modular system to integrate 3D brain region-specific organoids and study human neuronal migration and neural circuit formation in functional preparations that we named assembloids. We have actively applied these models in combination with studies in long-term ex vivo brain preparations to acquire a deeper understanding of human physiology, evolution and disease mechanisms.
We have carved a unique research program that combines rigorous in vivo and in vitro neuroscience, stem cell and molecular biology approaches to construct and deconstruct previously inaccessible stages of human brain development and function in health and disease.
We believe science is a community effort, and accordingly, we have been advancing the field by broadly and openly sharing our technologies with numerous laboratories around the world and organizing the primary research conference and the training courses in the area of cellular models of the human brain. -
Ryan Pate, MD, MS
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioDr. Ryan Pate is a board-certified adult psychiatrist with eligibility for board certification in geriatric psychiatry. He completed his general adult psychiatry training at Dartmouth-Hitchcock and pursued his geriatric psychiatry fellowship at Stanford Health Care. In addition to his psychiatry training, he is actively participating in the psychoanalytical psychotherapy fellowship offered by the Palo Alto division of the San Francisco Center for Psychoanalysis. Dr. Pate's research interests primarily focus on providing support for caregivers and developing group interventions tailored to older adults with mental health disorders. At Stanford, his professional practice primarily takes place in an outpatient setting, where he conducts appointments that involve a combination of medication management and psychotherapy interventions. Beyond his clinical work, Dr. Pate is dedicated to medical education.
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Alok Patel
Clinical Assistant Professor, Pediatrics
BioAlok Patel is a pediatric hospitalist, medical journalist, on-camera expert, producer, and devotee of creative, engaging science communication tactics. He currently serves as the Faculty Director of Communications for the Department of Pediatrics. Through this role, he helps coordinate creative media strategies for awareness, education, advocacy, recruitment and more.
Dr. Patel has extensive experience in broadcast journalism, on-camera work, script writing, podcast hosting, media consulting, and designing social media campaigns and hopes to lend these skills to his work in public health messaging. He currently works as a pediatric hospitalist within the department of pediatrics at Lucile Packard Children's Hospital. -
Anisha I Patel
Professor of Pediatrics (General Pediatrics) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsDr. Patel's research interests focus on reducing socioeconomic disparities in chronic diseases, including childhood obesity. Over the past 10 years, Dr. Patel has led numerous studies to encourage healthy beverage intake among children and adolescents. These studies include analyses of large national data sets, conduct of randomized controlled trials in schools, child care, and community settings to examine how interventions to increase children’s intake of water instead of sugar-sweetened beverages impact child health, and the evaluation of policy efforts to improve the healthfulness of beverages offered in schools and community settings.
Dr. Patel has a diverse funding portfolio ranging from the Robert Wood Johnson Foundation Healthy Eating Research Program, the W.K. Kellogg Foundation, and the National Institutes of Health. Dr. Patel has presented her research to local, national and international audiences. She has also been recognized for her research with awards from the American Academy of Pediatrics and the University of North Carolina, Chapel Hill School of Public Health. -
Chirag Patel, MD, PhD
Member, Cardiovascular Institute
Current Research and Scholarly InterestsNeuro-oncology, Clinical Trials, Tumor Treating Fields (TTFields), Molecular/PET Imaging, Neuroimaging, Immunotherapy, Big Data Analysis
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Lisa Patel
Clinical Associate Professor, Pediatrics
BioLisa Patel received her undergraduate degree in Biological Sciences from Stanford University. After college, she worked in Egypt, Brazil, and India on international development projects with community-based organizations and non-profits, focusing on conservation and development efforts. She then obtained her Master's in Environmental Sciences from the Yale School of the Environment and went on to be a Presidential Management Fellow for the Environmental Protection Agency, coordinating the US Government's efforts on clean air and safe drinking water projects in South Asia in collaboration with the World Health Organization. Realizing the critical and inextricable links between children's health and environmental issues, she obtained her medical degree from Johns Hopkins University and completed her residency in pediatrics at UCSF. For the last several years, she has used her extensive experience working for government, community organizations, and non-profits to advocate for children's health priorities in the US. She is previously the co-chair for the American Academy of Pediatrics Advocacy Committee, California Chapter 1 (AAP-CA1) and in her time helped launch the inaugural Advocating for Children Together conference for Northern California that is now a yearly occurrence. She co-founded the Climate and Health task force for AAP-CA1, and sits on the Executive Committee for the AAP's national Council on Environmental Health and Climate Change. She is formerly the rotation director for the pediatric resident's Community Pediatrics and Child Advocacy Rotation. She is currently the Executive Director for the Medical Society Consortium on Climate and Health and maintains a clinical practice as a pediatric hospitalist caring for newborns, premature infants, and children requiring hospitalization. She also sits on the Board of Our Children's Trust, the legal organization that represented youth in Held v. Montana.
Her work has appeared in the New England Journal of Medicine, the New York Times, the LA Times, Bloomberg News, and multiple state and local outlets. She is interviewed regularly for her expertise on climate, health, and equity for major national media outlets like the Washington Post, US News and World Report, CNN, among others. -
Meeta Raman Patel
Adjunct Clinical Assistant Professor, Pediatrics - Gastroenterology
BioDr. Patel has been working with children with autism and other disabilities for over 20 years. She is a Board Certified Behavior Analyst. Dr. Patel received a BS degree from the University of California at Davis in 1996 in Psychology with an emphasis in Biology. She continued her graduate training in Psychology at the University of Nevada, Reno. Dr. Patel received her PhD in Psychology with an emphasis in Behavior Analysis.
She completed a post-doctoral fellowship at the Kennedy Krieger Institute and Johns Hopkins University School of Medicine in 2001. Dr. Patel joined the faculty at the Marcus and Kennedy Krieger Institutes in 2001 and Emory University School of Medicine in 2002. Dr. Patel was a case manager in the Pediatric Feeding Disorders and Early Intervention Programs at the Marcus and Kennedy Krieger Institutes from 2001-2003. In 2003, she started Clinic 4 Kidz, which is a home-based Interdisciplinary Pediatric Feeding Disorders Program. Currently, she serves as the Executive Director of Clinic 4 Kidz.
Her research and clinical interests focus on treating feeding problems in children who have underlying medical issues (e.g., prematurity, failure to thrive [FTT], tube dependence, gastroesophageal reflux [GER], food allergies, etc.). In addition, she has expertise in working with children with autism, more specifically treating food selectivity by type and/or texture.
She currently serves on the editorial board of Behavioral Development which is a journal of the American Psychological Association. She formerly served on the editorial boards for the Journal of Applied Behavior Analysis and Education and Treatment of Children. Dr. Patel also serves as a guest reviewer for several journals. She has published over 20 research studies in peer-reviewed journals and has authored two invited book chapters. Dr. Patel has also been invited to present at numerous conferences and at various hospitals all over the country. -
Meghna D Patel
Clinical Associate Professor, Pediatrics - Cardiology
Current Research and Scholarly InterestsMy current academic focus is in chronic heart failure and ventricular assist device.
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Michele Lanpher Patel
Instructor, Medicine - Stanford Prevention Research Center
BioMichele L. Patel, PhD is an Instructor at the Stanford University School of Medicine. Her research focuses on optimizing digital health interventions for treating & preventing obesity. She is particularly interested in improving engagement in these interventions and examining the impact of psychosocial factors on treatment success.
Dr. Patel received a K23 career development award from NIH (2022-2027). This work investigates the most potent combination of self-monitoring strategies in a behavioral weight loss intervention for adults with overweight or obesity. Dr. Patel is interested in using digital tools such as commercial apps, wearables, text-messaging, and telehealth to improve access to and engagement in treatment.
Dr. Patel received her BA in psychology from Duke University in 2010 and her PhD in clinical psychology from Duke in 2018. She completed her clinical internship at the VA Palo Alto, specializing in behavioral medicine, and her postdoctoral fellowship at the Stanford Prevention Research Center.
Primary Research Interests:
-- Conducting clinical trials to evaluate digital health interventions for obesity
-- Improving engagement in self-monitoring and other behavioral intervention strategies
-- Examining the impact of psychosocial factors (e.g., health literacy, stress) on treatment success
-- Applying the Multiphase Optimization Strategy (MOST) framework to efficiently construct behavioral interventions
Methods:
-- RCTs, including factorial designs
-- systematic reviews
-- signal detection analysis (upcoming)
-- mixed methods (upcoming)
