Stanford University
Showing 4,621-4,640 of 4,787 Results
-
John Fraser Wright
Professor (Research), Pediatrics - Stem Cell Transplantation
BioJ Fraser Wright, PhD
Dr. Wright received his PhD in 1989 from the University of Toronto (Biochemistry) for studies
characterizing the interaction of complement with IgM, and completed post-doctoral studies at INSERM
/ CENG Grenoble, France in molecular immunology focused on antigen processing and presentation. He
was awarded a CRCS/ MRC Scholarship, gaining faculty appointment at the University of Toronto. In
1996 he joined industry as a Scientist at Pasteur Sanofi, contributing there to the development of
vaccines and cancer immunotherapies, and subsequently as Director of Development and Clinical
Manufacturing at Avigen, a gene therapy company that pioneered AAV-based investigational gene
therapies for hemophilia and Parkinson’s disease. In 2004 he returned to academia, establishing and
directing the Clinical Vector Facility at the Center for Cellular and Molecular Therapeutics at Children’s
Hospital of Philadelphia, and gaining faculty appointment at the University of Pennsylvania Perelman
School of Medicine as professor of Pathology and Laboratory Medicine. Dr. Wright has contributed to
several clinical development programs in gene therapy, including for Luxturna and Kymriah, the first
gene therapies for a genetic (RPE65 deficiency) and non-genetic (CAR-T immunotherapy) disease,
respectively, approved in the United States, and for the first gene therapy clinical trial that delivered an
AAV-vectorized monoclonal antibody to human subjects for HIV passive immunity. He is a Co-founder of
Spark Therapeutics, serving there and subsequently at Axovant as Chief Technology Officer. In 2019 Dr.
Wright joined Stanford University as Professor of Pediatrics at The Center for Definitive and Curative
Medicine (CDCM). His research program aims to address key immunological barriers to gene therapy
through innovative approaches to viral vector design and generation, and to develop vectorized
antibodies for serious human diseases. -
Albert Y. Wu, MD, PhD, FACS
Assistant Professor of Ophthalmology
Current Research and Scholarly InterestsMy translational research focuses on using autologous stem cells to recreate a patient’s ocular tissues for potential transplantation. We are generating tissue from induced pluripotent stem cells to treat limbal stem cell deficiency in patients who are bilaterally blind. By applying my background in molecular and cellular biology, stem cell biology, oculoplastic surgery, I hope to make regenerative medicine a reality for those suffering from orbital and ocular disease.
-
Bryan Wu, MD
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
BioDr. Wu is a board-certified cardiologist at Stanford Health Care. He is also a clinical assistant professor in the Division of Cardiovascular Medicine. His areas of clinical focus include general and preventive cardiology with a particular interest in cardiac imaging. Dr. Wu has board certification in echocardiography, cardiovascular CT, and cardiac nuclear imaging.
Dr. Wu speaks fluent Chinese and Spanish and embraces racial, ethnic, and socioeconomic diversity in his clinical care. He has international clinical/research experiences in Italy and Mexico, and truly enjoys meeting and working with people from distinctive backgrounds.
Dr. Wu is passionate about clinical research. He has pursued scholarly work on the utilization of therapeutic drug monitoring for antihypertensive therapy and statins to help patients from low socioeconomic backgrounds improve their medication adherence. He is also involved in research on advanced cardiac imaging and has actively investigated the applications of cardiac CT in electrophysiology interventions.
Dr. Wu’s research has been published in peer-reviewed journals such as the International Journal of Cardiology and Journal of Vascular Surgery. He has presented his work at regional and national meetings, including the American Heart Association’s annual Scientific Sessions.
Dr. Wu is a member of the American College of Physicians, American Heart Association, and American Medical Association. -
Hsi-Yang Wu
Member, Bio-X
Current Research and Scholarly InterestsI am interested in how the brain matures to control the bladder and external sphincter to achieve urinary continence. Using functional MRI of the brain, we are investigating if certain patterns of activity will predict which children will respond to therapy for incontinence.
-
Joseph C. Wu, MD, PhD
Director, Stanford Cardiovascular Institute, Simon H. Stertzer, MD, Professor and Professor of Radiology
Current Research and Scholarly InterestsDrug discovery, drug screening, and disease modeling using iPSC.
-
Joy Wu
Professor of Medicine (Endocrinology)
Current Research and Scholarly InterestsMy laboratory focuses on the pathways that regulate the differentiation of mesenchymal stem cells into the osteoblast and adipocyte lineages. We are also studying the role of osteoblasts in the hematopoietic and cancer niches in the bone marrow microenvironment.
-
Sean M. Wu
Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsMy lab seeks to identify mechanisms regulating cardiac lineage commitment during embryonic development and the biology of cardiac progenitor cells in development and disease. We believe that by understanding the transcriptional and epigenetic basis of cardiomyocyte growth and differentiation, we can identify the most effective ways to repair diseased adult hearts. We employ mouse and human embryonic and induced pluripotent stem cells as well as rodents as our in vivo models for investigation.
-
Courtney Wusthoff, MD
Professor of Neurology (Pediatric Neurology) and, by courtesy, of Pediatrics (Neonatology)
Current Research and Scholarly InterestsMy projects focus on clinical research in newborns with, or at risk, for brain injury. I use EEG in at-risk neonates to better understand the underlying pathophysiology of risk factors that may lead to worse outcomes. I am particularly interested in neonatal seizures and how they may exacerbate perinatal brain injury with a goal to identify treatments that might protect the vulnerable brain. I am also interested in EEG in other pediatric populations, as well as medical ethics and global health.
-
Joanna Wysocka
Lorry Lokey Professor and Professor of Developmental Biology
Current Research and Scholarly InterestsThe precise and robust regulation of gene expression is a cornerstone for complex biological life. Research in our laboratory is focused on understanding how regulatory information encoded by the genome is integrated with the transcriptional machinery and chromatin context to allow for emergence of form and function during human embryogenesis and evolution, and how perturbations in this process lead to disease.
-
Tony Wyss-Coray, PhD
D. H. Chen Professor II
Current Research and Scholarly InterestsUse of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration.
-
James Xie
Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine
BioDr. James Xie is a board certified pediatrician and pediatric anesthesiologist at Stanford University School of Medicine. His goal is to improve patient care and promote health equity with health information technologies. Currently he is a clinical informatics physician (CI-MD) and Epic physician builder at Stanford Children's Health.
Dr. Xie studied computer science and medicine at Stanford University, followed by a combined residency in general pediatrics at Boston Children's Hospital and Boston Medical Center and anesthesiology at Brigham and Women's Hospital. After residency, he completed a fellowship in pediatric anesthesiology at Stanford Children's Health where he subsequently joined the faculty.
