Stanford University
Showing 1,851-1,900 of 2,264 Results
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Branimir I. Sikic, M. D.
Professor of Medicine (Oncology), Emeritus
Current Research and Scholarly InterestsResearch Interests: cancer pharmacology, mechanisms of resistance to anticancer drugs, regulation and function of MDR1 and tubulin genes, CD47 as a target for activation of anticancer macrophases, Phase I trials of new drugs, gene expression profiling of cancers
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Julia Fridman Simard
Associate Professor of Epidemiology and Population Health, of Medicine (Immunology & Rheumatology) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine)
BioJulia Fridman Simard, ScD, is an Associate Professor of Epidemiology & Population Health, and, by courtesy, of Medicine in Immunology and Rheumatology and Obstetrics and Gynecology in Maternal Fetal Medicine at Stanford University School of Medicine.
Dr. Simard earned her Masters and Doctorate of Science in Epidemiology degrees at the Harvard School of Public Health. During that time she trained with investigators at the Section of Clinical Sciences, Division of Rheumatology, Immunology, and Allergy at Brigham and Women’s Hospital and the Cardiovascular Epidemiology Research Unit at Beth Israel Deaconess Medical Center. In 2008, Dr. Simard relocated to Sweden to begin a Postdoctoral Fellowship in Clinical Epidemiology at the Karolinska Institutet in Stockholm. She became an Assistant Professor in their Clinical Epidemiology Unit in 2011, and was later honored with a Karolinska Institutet Teaching Award. Leveraging the population-based registers of Sweden, Dr. Simard initiated a national register linkage study to examine the utility of registers in Systemic Lupus Erythematosus (SLE) research and develop an extensive data repository for future epidemiologic investigations.
While maintaining a close collaboration with the Karolinska Institutet, she joined Stanford’s Epidemiology faculty in 2013. Dr. Simard studies outcomes such as malignancy, stroke, infection, and mortality, in patients with systemic autoimmune rheumatic diseases with a focus on systemic lupus erythematosus. Recently her primary research focus has shifted to the intersection between reproductive epidemiology and rheumatic disease fueled by a K01 career development award from the NIH (NIAMS) to study maternal and fetal outcomes in systemic lupus pregnancy. This led to collaborations with colleagues at Stanford, throughout the US, and abroad, and a series of projects focused on the diagnosis of preeclampsia and associated risks in pregnant women with systemic lupus. Dr. Simard was awarded a Peter Joseph Pappas Research Grant from the Preeclampsia Foundation for her lab's work examining preeclampsia risk in high-risk populations, and a McCormick Faculty Award from Stanford Medicine to take important steps towards disentangling preeclampsia from lupus nephritis. Dr. Simard is leading an international study of hydroxychloroquine in lupus pregnancy leveraging mixed methods in partnership with qualitative researchers, patients, clinicians, and epidemiologists in Sweden, Canada, and in the United States.
In addition to these issues of misclassification in reproductive rheumatology questions, Dr. Simard's lab is also interested in how misclassification, missed opportunities, and misdiagnosis contribute to disparities in complex conditions such as systemic lupus. In addition to methodologic issues around misclassification and bias and the largely clinical epidemiology focus of her work, Dr. Simard's work examines social determinants of health and health disparities. Dr. Simard was recently awarded an R01 from NIH (NIAID) to study the role of cognitive and unconscious bias in clinical decision making for female-predominant diseases including lupus. -
Benjamin Singer
Postdoctoral Scholar, Infectious Diseases
BioBen Singer is a postdoctoral scholar with interests in mathematical epidemiology and global public health. Ben's research career began with an internship at the Okinawa Institute of Science and Technology, where he applied quantitative skills he had learnt studying physics at the University of Oxford to the study of nematode locomotion. Ben further pursued quantitative methods in life sciences in the Interdisciplinary Bioscience Doctoral Training Partnership at the University of Oxford, earning a DPhil (PhD equivalent) in mathematical methods for evaluating pandemic risk and control. During these studies he maintained an interest in global public health policy, interning with the UK government's Department for International Development, where he developed models of international COVID-19 vaccine distribution. Ben is now working in Nathan Lo's research group at Stanford, creating infectious disease models informing public health policy for schistosomiasis, hepatitis E, and other infections.
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Gulshan Singh
Postdoctoral Scholar, Gastroenterology
Current Research and Scholarly InterestsMy current research interest is to understand the host-microbial pathways in intestinal inflammation. I am working to explore cellular heterogeneity at single immune cell level in systemic and local regions of the intestine that are associated with different Inflammatory bowel disease conditions.
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Sundeep Singh
Clinical Associate Professor, Medicine - Gastroenterology & Hepatology
BioAfter living and training throughout the country, I am excited to be part of the Stanford team. As a result of both my personal experiences and training, I am passionate about ensuring that patients receive appropriate diagnostic testing and treatment options in order to improve people's quality of life. In collaboration with my amazing colleagues, I am confident in the high quality and easily accessible care we are able to provide to patients across northern California.
While my interest is most in inflammatory bowel disease, I am also interested in the interaction between mental health, incentives, and emerging therapies in gastroenterology. -
Upinder Singh
Stanford Medicine Professor of Infectious Disease and Professor of Medicine (Infectious Diseases & Geographic Medicine) and of Microbiology and Immunology
Current Research and Scholarly InterestsOur lab elucidates the molecular basis of pathogenesis of the protozoan parasite Entamoeba histolytica. We use genetic and genomic approaches to identify novel virulence determinants and to characterize the global epidemiology of the parasite.
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Sidhartha Sinha
Assistant Professor of Medicine (Gastroenterology and Hepatology)
Current Research and Scholarly InterestsThere are two primary and overlapping emphases of my research, both of which are driven and united by needs-based innovation and translational potential:
(1) Understanding the microenvironment of the inflamed versus normal gut in order to identify better therapeutic targets for people with immune-¬mediated GI disorders. Here, our investigations include understanding the influence and interactions of pharmacologic and dietary interventions on gut microbiome/metabolomic changes and the host immune response. In the context of providing patients with new understanding and solutions for their disease, I have led and advised on the design of both pilot and large clinical trials (including new FDA approved therapies) for anti-inflammatory therapies;
(2) Applying novel approaches and technologies (including natural language processing, computer vision, and reinforcement learning) to identify and address unmet clinical needs. In this area we have ongoing and published efforts in my lab to validate and develop solutions to pressing clinical needs. We have developed/led new drug delivery technologies with a multidisciplinary team that have shown strong potential in ongoing human IBD clinical trials. My lab has utilized both supervised and unsupervised approaches to analyze social media discourse and unstructured data sets for identifying patient needs that are rarely addressed in clinical settings. We have gained insights into patient perceptions around preventative health interventions, such as health screening and diet, including the dearth of evidence-based dietary recommendations to treat IBD (despite strong patient desire for solutions in this domain). -
Tammy Lisa Sirich
Assistant Professor of Medicine (Nephrology)
Current Research and Scholarly InterestsI conduct translational research focused on uremia and dialysis. I use mass spectrometry to conduct studies testing ways to reduce levels of solutes and examining the contribution of uremic solutes to illness.
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Kelley M. Skeff, MD, PhD
George DeForest Barnett Professor of Medicine
Current Research and Scholarly InterestsDevelopment and evaluation of improved teaching methods; assessment of teacher's attitudes toward their teaching role; study of clinical teaching; evaluation of alternative methods of learning in clinical clerkships (e.g. computer assisted instruction, video tape review, etc.).
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Peter Michael Sklarin
Adjunct Clinical Assistant Professor, Medicine - Primary Care and Population Health
BioDr. Sklarin practices endocrinology at Menlo Medical Clinic. He is a graduate of Harvard College, where he majored in biology. He attended medical school at the University of California, San Francisco, completed his internal medicine residency at Brigham and Women’s Hospital in Boston, and completed his endocrinology fellowship at the University of California, San Francisco.
Dr. Sklarin is board certified in Endocrinology, Diabetes, and Metabolism and treats patients with a wide variety of endocrine disorders. He has special expertise in thyroid ultrasound and ultrasound guided fine-needle aspiration and directs the Menlo Clinic bone density center.
In his free time Dr. Sklarin enjoys spending time with his family, playing tennis, running, biking, swimming, and doing triathlons. -
Grant M. Smith, MD
Clinical Assistant Professor, Medicine - Primary Care and Population Health
BioDr. Grant Smith is a palliative care physician and Clinical Assistant Professor of Medicine at the Stanford School of Medicine. He is the medical director of the Stanford Palliative Care Center of Excellence (PCCOE) Community Partnerships Team, and he is the lead for quality improvement in advance care planning in the Division of Primary Care and Population Health. Dr. Smith graduated with a Bachelor of Science in psychology from Duke University. He received his medical degree from Harvard Medical School. He completed residency in internal medicine at the University of California, San Francisco with a focus in primary care, followed by a chief resident year at the Zuckerberg San Francisco General Hospital. He subsequently completed his palliative care fellowship at the University of California, San Francisco. As part of the Stanford faculty, he is an attending on the palliative care inpatient service and as a provider in the outpatient palliative care clinic in Palo Alto.
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Melody Smith, MD, MS
Assistant Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy)
BioDr. Smith is a board-certified, fellowship-trained medical oncologist and hematologist. She is an assistant professor in the Department of Medicine in the Division of Blood & Marrow Transplantation and Cellular Therapy.
She is also a physician-scientist who conducts extensive research. As a medical student, she completed a fellowship at the National Institutes of Health (NIH) in the Clinical Research Training (now, the Medical Research Scholars) Program. Subsequently, following her clinical fellowship, she was a post-doctoral researcher at Memorial Sloan Kettering Cancer Center. The research in her lab focuses on investigations of the biology of chimeric antigen receptor (CAR) T cells to improve the efficacy and safety of this therapy (1) by investigating donor (Nature Medicine, 2017) and off-the-shelf CAR T cells in mouse models and (2) by assessing mechanisms for the impact of the intestinal microbiome on CAR T cell response (Nature Medicine, 2022).
Dr. Smith presents the findings of her research at regional, national, and international conferences. Further, she has co-authored articles on topics within the field of cancer immunology, including cancer immunotherapy, stem cell transplantation, and CAR T cell therapy. Her work has appeared in journals, among others Nature, Nature Immunology, Nature Medicine, Blood, and Transplantation and Cellular Therapy. She serves a peer reviewer for publications in journals, such as NEJM Evidence, Science Advances, Blood, Cancer Cell, and Molecular Therapy. She also has contributed to chapters in books, including Pocket Oncology, Current Concepts and Controversies in Hematopoietic Cell Transplantation, and Advanced Concepts in Human Immunology: Prospects for Disease Control.
She has earned numerous honors; the American Society of Hematology (ASH), the Society for Immunotherapy of Cancer, the European Society for Blood and Marrow Transplantation, and several other professional organizations have recognized her achievements as a clinician, researcher, and scholar.
Dr. Smith is a member of the ASH Committee on Emerging Gene and Cell Therapies and the ASH Committee on Diversity, Equity & Inclusion. Additionally, she serves on committees within the institution and professional organizations focused on promoting diversity among hematology and cell therapy specialists. -
Sulaiman Somani
Clinical Scholar, Medicine
Resident in Med/Hospital MedicineCurrent Research and Scholarly Interestscomputer vision, personalized medicine, cardiology, clinical informatics
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Irene Sonu
Clinical Associate Professor, Medicine - Gastroenterology & Hepatology
BioI am passionate about gut health and strive to provide the best care to my patients. I specialize in complex motility disorders of the gastrointestinal tract. My areas of clinical expertise include achalasia, dysphagia, eosinophilic esophagitis, gastroesophageal reflux disease, gastroparesis, functional dyspepsia, irritable bowel syndrome, and pelvic floor dysfunction. I also see patients in need of fecal microbiota transplant for recurrent C. difficile infection.