Stanford University

Showing 1,781-1,790 of 2,474 Results

• 

  Carla Pugh, MD, PhD

  Thomas Krummel Professor
  

  Current Research and Scholarly InterestsThe Technology Enabled Clinical Improvement (T.E.C.I.) Center is a multidisciplinary team of researchers dedicated to the design and implementation of advanced engineering technologies that facilitate data acquisition relating to clinical performance.
• 

  Elisabetta Viani Puglisi

  Associate Professor (Research) of Structural Biology
  

  Current Research and Scholarly InterestsViral infections and subsequent host response depend on multiple RNA-protein interaction. My research focuses on the structural and functional characterization of RNA-protein complexes involved in viral infection. Current research aims to understand how the Human Immunodeficiency Virus (HIV) initiates its replication upon host infection. We use NMR spectroscopy and x-ray crystallography to study the structure of the initiation complex, formed by a host tRNA and HIV genomic RNA, coupled with biochemical and biophysical methods to understand functional properties. The goal of this research is to gain a molecular view of HIV replication initiation, and use this information to develop new therapeutic approaches to combat HIV.
• 

  Joseph (Jody) Puglisi

  Jauch Professor and Professor of Structural Biology
  

  Current Research and Scholarly InterestsThe Puglisi group investigates the role of RNA in cellular processes and disease. We investigate dynamics using single-molecule approaches. Our goal is a unified picture of structure, dynamics and function. We are currently focused on the mechanism and regulation of translation, and the role of RNA in viral infections. A long-term goal is to target processes involving RNA with novel therapeutic strategies.
• 

  Bali Pulendran

  Violetta L. Horton Professor, Director, Institute for Immunity, Transplantation and Infection and Professor of Microbiology and Immunology
  
• 

  Patrick Lee Purdon

  Professor of Anesthesiology, Perioperative and Pain Medicine (Department Research) and, by courtesy, of Bioengineering
  

  BioMy research integrates neuroimaging, biomedical signal processing, and the systems neuroscience of general anesthesia and sedation.
  
  We are a neuroengineering lab focused on brain dynamics, brain health, and the neural mechanisms of anesthesia. Our research aims to understand the brain dynamics of aging, Alzheimer’s disease, child development, sleep, anesthesia, and consciousness. We use this knowledge to develop novel technologies for brain monitoring and physiological control. We also teach anesthesiologists how to use EEG to provide personalized anesthesia care.
• 

  Rajan Puri, MD, MPH

  Physician, Environmental Health and Safety (EH&S)
  Physician, Environmental Health and Safety (EH&S)
  

  • Contact Info

  • Other Names:

    Raj Puri
• 

  Stanley Qi

  Associate Professor of Bioengineering and, by courtesy, of Biomedical Data Science
  

  BioStanley Qi (publishing as Lei S. Qi) is a pioneer in the field of genome engineering and the architect of the foundational technologies that transitioned CRISPR from a "cutting" tool into a universal platform for Programmable Biology. As the inventor of CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa), Qi established the first methods for the precise, reversible, and targeted regulation of the human genome without altering the DNA sequence.
  
  The Qi Lab integrates scalable genomic perturbation with live-cell and super-resolution imaging and computation-guided design to redefine the boundaries of cellular control. Under Dr. Qi’s leadership, the group has fundamentally expanded the genome engineering toolbox, evolving CRISPR from a single editing tool into a multidimensional platform for the precise control of dynamic and spatial cell states. This work includes establishing foundational technologies and architectures for precise epigenetic editing, multiplexed regulation of the transcriptome, programmable 3D genome organization, and spatial control of RNA logistics. By pioneering real-time visualization of chromatin dynamics and RNA in living cells, the lab provides an unprecedented window into the fundamental "control principles of life."
  
  This principle-driven technology lineage has moved into the clinic, with the lab's compact epigenetic editor currently in first-in-human clinical testing for FSHD muscular dystrophy (NCT06907875). This milestone represents a core mission of the lab: translating foundational engineering into next-generation therapeutics that act predictably as dynamic, complex systems.
  
  Beyond single-cell control, the Qi Lab is building a framework for synthetic cell–cell communication, with a particular emphasis on the bidirectional interplay between immune cells and neurons. The lab’s goal is to move beyond describing molecular parts to discovering fundamental control principles in living systems: how regulatory landscapes create stable states and memory, how spatial genome–RNA organization shapes dynamic responses, and how engineered cell–cell interactions can generate emergent multicellular behaviors.
  
  By integrating computational design with experimental biology, Dr. Qi aims to identify the generalizable rules linking molecular programs to systems-level physiology. He is a Chan Zuckerberg Biohub Investigator and an Institute Scholar at the Sarafan ChEM-H, and is dedicated to shaping the technical and ethical frameworks that will define the future of human genome engineering.

  • Contact Info

  • Other Names:

    Lei S. Qi

    Lei (Stanley) Qi

  • Web page:

    https://profiles.stanford.edu/stanleyqi
• 

  Xiang Qian

  Stanford Medicine Endowed Director
  Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
  Clinical Professor (By courtesy), Neurosurgery
  

  Current Research and Scholarly InterestsClinical Interests
  -Pain Medicine:
  Facial pain
  Migraine and headache
  Trigeminal Neuralgia and Glossopharyngeal neuralgia
  Cancer Pain
  Spine Disease
  Neuropathic pain
  Interventional Surgery
  CT guided Procedure
  Opioid Management
  
  -Facial Nerve neuralgia and neuropathy
  Hemifacial Spasm
  CT guided awake RFA of facial nerve
  
  Research Interests:
  -Medical device development
  -AI based headache diagnosis and management
  -CT guided intervention
  -Intra-nasal endoscopy guided procedure
  -Optogenetics
  -Mechanisms of neuropathic pain
  -Ion channel and diseases
  -Neurotoxicity of anesthetics
• Chun Ming Qiang

  Affiliate, Geballe Laboratory for Advanced Materials
  
• 

  Jian Qin

  Associate Professor of Chemical Engineering
  

  BioJian Qin is an Associate Professor in the Department of Chemical Engineering at the Stanford University. His research focuses on development of microscopic understanding of structural and physical properties of soft matters by using a combination of analytical theory, scaling argument, numerical computation, and molecular simulation. He worked as a postdoctoral scholar with Juan de Pablo in the Institute for Molecular Engineering at the University of Chicago and with Scott Milner in the Department of Chemical Engineering at the Pennsylvania State University. He received his Ph.D. in the Department of Chemical Engineering and Materials Science at the University of Minnesota under the supervision of David Morse and Frank Bates. His research covers self-assembly of multi-component polymeric systems, molecular origin of entanglement and polymer melt rheology, coacervation of polyelectrolytes, Coulomb interactions in dielectrically heterogeneous electrolytes, and surface charge polarizations in particulate aggregates in the absence or presence of flow.