Bio-X


Showing 1-10 of 795 Results

  • Ronald W. Davis

    Ronald W. Davis

    Professor of Biochemistry and of Genetics

    Current Research and Scholarly InterestsWe are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.

  • Christos E. Constantinou

    Christos E. Constantinou

    Associate Professor of Urology, Emeritus

    Current Research and Scholarly InterestsMy main recent interest is the application of Biomedical Engineering approaches for the clinical visualization and characterization of the static and dynamic properties of pelvic floor function. This extends to ultrasound Imaging and image processing, construction of computer models and biomechanics analysis of pelvic floor function. It is envisioned that these considerations are important constituents of the clinical evaluation of patients with lower urinary tract dysfunction and urodynamics.

  • Darrell Wilson

    Darrell Wilson

    Professor of Pediatrics (Endocrinology) at the Lucile Salter Packard Children's Hospital

    Current Research and Scholarly InterestsMy research interests cover a number of areas in Pediatric Endocrinology and Diabetes. I am PI of the Stanford Center for the NIH-funded Type-1 Diabetes TrialNet group. TrialNet conducts clinical trials directed at preventing or delaying the onset of Type 1 diabetes. I am an investigator in DirecNet, another NIH-funded study group, which is devoted to evaluating glucose sensors and the role of technology on the management of diabetes.

  • Daniel Herschlag

    Daniel Herschlag

    Professor of Biochemistry and, by courtesy, of Chemical Engineering and of Chemistry

    Current Research and Scholarly InterestsOur research is aimed at understanding the chemical and physical behavior underlying biological macromolecules and systems, as these behaviors define the capabilities and limitations of biology. Toward this end we study folding and catalysis by RNA, as well as catalysis by protein enzymes.

  • Shoshana Levy

    Shoshana Levy

    Professor (Research) of Medicine (Oncology)

    Current Research and Scholarly InterestsOur research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria.

  • Julie Theriot

    Julie Theriot

    Professor of Biochemistry and of Microbiology and Immunology

    Current Research and Scholarly InterestsWe study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis.

  • Peter K.  Jackson

    Peter K.  Jackson

    Professor of Microbiology and Immunology (Baxter Labs) and of Pathology

    Current Research and Scholarly InterestsCell cycle and cyclin control of DNA replication .

  • Eugene Butcher

    Eugene Butcher

    Klaus Bensch Professor in Pathology

    Current Research and Scholarly InterestsOur interests include:
    1) The physiology and significance of lymphocyte homing in local and systemic immunity;
    2) biochemical and genetic studies of molecules that direct leukocyte recruitment;
    3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines;
    4) vascular differentiation in normal and pathologic inflammatory states;
    5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs.

  • Douglas Vollrath

    Douglas Vollrath

    Associate Professor of Genetics and, by courtesy, of Ophthalmology

    Current Research and Scholarly InterestsThe Vollrath lab works to uncover molecular mechanisms relevant to the health and pathology of the outer retina. We study the retinal pigment epithelium (RPE), a cell monolayer adjacent to photoreceptors that performs a variety of tasks crucial for retinal homeostasis. Specific areas of interest include the circadian regulation of RPE phagocytosis of photoreceptor outer segment tips, and how RPE metabolic dysfunction contributes to retinal degenerative diseases.

  • Trevor Hastie

    Trevor Hastie

    John A. Overdeck Professor, Professor of Statistics and of Biomedical Data Sciences

    Current Research and Scholarly InterestsFlexible statistical modelling, datamining, bioinformatics, and statistical computing.