Showing 821-830 of 838 Results

  • Jiangbin Ye

    Jiangbin Ye

    Assistant Professor of Radiation Oncology

    Current Research and Scholarly InterestsOne hallmark of cancer is that malignant cells modulate metabolic pathways to promote cancer progression. My professional interest is to investigate the causes and consequences of the abnormal metabolic phenotypes of cancer cells in response to microenvironmental stresses such as hypoxia and nutrient deprivation, with the prospect that therapeutic approaches might be developed to target these metabolic pathways to improve cancer treatment.

  • Ellen Yeh

    Ellen Yeh

    Assistant Professor of Biochemistry, of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsThe chemistry and biology of the unusual plastid organelle, the apicoplast, in malaria parasites

  • David C. Yeomans

    David C. Yeomans

    Associate Professor of Anesthesiology, Perioperative and Pain Medicine

    Current Research and Scholarly InterestsPhysiology of different pain types; Biomarkers of pain and inflammation; Gene Therapy for Pain

  • Paul Yock, MD

    Paul Yock, MD

    The Martha Meier Weiland Professor in the School of Medicine and Professor of Bioengineering

    Current Research and Scholarly InterestsHealth technology innovation using the Biodesign process: a systematic approach to the design of biomedical technologies based on detailed clinical and economic needs characterization. New approaches for interdisciplinary training of health technology innovators, including processes for identifying value opportunities in creating new technology-based approaches to health care.

  • Jong H. Yoon

    Jong H. Yoon

    Associate Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult) at the Palo Alto Veterans Affairs Health Care System

    Current Research and Scholarly InterestsMy research seeks to discover the brain mechanisms responsible for schizophrenia and to translate this knowledge into the clinic to improve how we diagnose and treat this condition. Towards these ends, our group has been developing cutting-edge neuroimaging tools to identify neurobiological abnormalities and test novel systems-level disease models of psychosis and schizophrenia directly in individuals with these conditions.

    We have been particularly interested in the role of neocortical-basal ganglia circuit dysfunction. A working hypothesis is that some of the core symptoms of schizophrenia are attributable to impairments in neocortical function that results in disconnectivity with components of the basal ganglia and dysregulation of their activity. The Yoon Lab has developed new high-resolution functional magnetic resonance imaging methods to more precisely measure the function of basal ganglia components, which given their small size and location deep within the brain has been challenging. This includes ways to measure the activity of nuclei that store and control the release of dopamine throughout the brain, a neurochemical that is one of the most important factors in the production of psychosis in schizophrenia and other neuropsychiatric conditions.

  • Greg Zaharchuk

    Greg Zaharchuk

    Associate Professor of Radiology

    Current Research and Scholarly InterestsImproving medical image quality using deep learning
    Imaging of cerebral hemodynamics with MRI and CT
    Noninvasive oxygenation measurement with MRI
    Clinical imaging of cerebrovascular disease
    Imaging of cervical artery dissection
    MR/PET in Neuroradiology
    Resting-state fMRI for perfusion imaging and stroke

  • Jamil Zaki

    Jamil Zaki

    Assistant Professor of Psychology

    Current Research and Scholarly InterestsMy research focuses on the cognitive and neural bases of social behavior, and in particular on how people respond to each other's emotions (empathy), why they conform to each other (social influence), and why they choose to help each other (prosociality).

  • Dick Zare

    Dick Zare

    Marguerite Blake Wilbur Professor in Natural Science and Professor, by courtesy, of Physics

    Current Research and Scholarly InterestsMy research group is exploring a variety of topics that range from the basic understanding of chemical reaction dynamics to the nature of the chemical contents of single cells.

    Under thermal conditions nature seems to hide the details of how elementary reactions occur through a series of averages over reagent velocity, internal energy, impact parameter, and orientation. To discover the effects of these variables on reactivity, it is necessary to carry out studies of chemical reactions far from equilibrium in which the states of the reactants are more sharply restricted and can be varied in a controlled manner. My research group is attempting to meet this tough experimental challenge through a number of laser techniques that prepare reactants in specific quantum states and probe the quantum state distributions of the resulting products. It is our belief that such state-to-state information gives the deepest insight into the forces that operate in the breaking of old bonds and the making of new ones.

    Space does not permit a full description of these projects, and I earnestly invite correspondence. The following examples are representative:

    The simplest of all neutral bimolecular reactions is the exchange reaction H H2 -> H2 H. We are studying this system and various isotopic cousins using a tunable UV laser pulse to photodissociate HBr (DBr) and hence create fast H (D) atoms of known translational energy in the presence of H2 and/or D2 and using a laser multiphoton ionization time-of-flight mass spectrometer to detect the nascent molecular products in a quantum-state-specific manner by means of an imaging technique. It is expected that these product state distributions will provide a key test of the adequacy of various advanced theoretical schemes for modeling this reaction.

    Analytical efforts involve the use of capillary zone electrophoresis, two-step laser desorption laser multiphoton ionization mass spectrometry, cavity ring-down spectroscopy, and Hadamard transform time-of-flight mass spectrometry. We believe these methods can revolutionize trace analysis, particularly of biomolecules in cells.

  • Christopher K. Zarins

    Christopher K. Zarins

    Walter Clifford Chidester and Elsa Rooney Chidester Professor of Surgery, Emeritus

    Current Research and Scholarly InterestsHemodynamic factors in atherosclerosis, pathogenesis of, aortic aneurysms, carotid plaque localization and complication, anastomotic intimal hyperplasia, vascular biology of artery wall, computational fluid dynamics as applied to blood flow and vascular disease.