Wu Tsai Human Performance Alliance
Showing 201-210 of 312 Results
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Paul Nuyujukian
Assistant Professor of Bioengineering and of Neurosurgery and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsOur group explores neuroengineering and its application to both basic and clinical neuroscience. Our goal is to develop brain-machine interfaces as a platform technology for a variety of brain-related medical conditions including stroke and epilepsy.
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Johanna O'Day
Scientific Program Manager - Education and Communications
BioI believe in using human-centered design and bioengineering to improve health. I have developed open-source tools that use wearables to better understand and improve mobility. I am passionate about building empathetic communities equipped with the skills and knowledge to make our world healthier, smarter, and more collaborative.
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Jelena Obradović
Professor of Education
Current Research and Scholarly InterestsAdaptation, resilience, and developmental psychopathology of disadvantaged children populations; Stress reactivity and biological sensitivity to contextual influences; Executive function and self-regulatory abilities; Effects of risk, adversity, and social status on children’s development.
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Michelle Odden
Associate Professor of Epidemiology and Population Health
Current Research and Scholarly InterestsMultilevel - from cells to society - epidemiologic study of healthy aging
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Allison Okamura
Richard W. Weiland Professor in the School of Engineering and Professor of Mechanical Engineering
Current Research and Scholarly InterestsMy research focuses on developing the principles and tools needed to realize advanced robotic and human-machine systems capable of physical interaction. Application areas include surgery, simulation and training, rehabilitation, prosthetics, neuromechanics, exploration of hazardous and remote environments (e.g. space), design, and education.
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Marily Oppezzo
Instructor, Medicine - Stanford Prevention Research Center
BioMarily Oppezzo is a behavioral and learning scientist. She completed her doctorate in Educational Psychology at Stanford in 2013. She also is a registered dietitian and has her master's of nutritional science. She completed her dietetic internship at the Palo Alto Veterans Hospital, and currently consults as a sports dietitian for Stanford's Runsafe program. Her research interests leverage her interdisciplinary training, with a focus on how to get people to change to improve their health and well-being. Specifically, these areas include: using social media to motivate physical activity changes in those with or at risk for heart disease; culturally tailoring nutrition and physical activity recommendations and education materials for an Alaskan native population; how walking can be used to improve people's cognitive and creative thinking; and applying learning theories to medical education topics.
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Lars Osterberg, MD, MPH
Professor (Teaching) of Medicine (Primary Care and Population Health)
Current Research and Scholarly InterestsBarriers to Humanism
Collaborative Faculty Development in Improving Humanism and Professionalism
Using Radiofrequency Identificaton technology to improve medication adherence
Impact of Learning Communities on Medical Education -
Sergiu P. Pasca
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences and Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program
Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
To address this, we are developing bottom-up approaches to generate and assemble, from multi-cellular components, human neural circuits in vitro and in vivo.
We introduced the use of instructive signals for deriving from human pluripotent stem cells self-organizing 3D cellular structures named brain region-specific spheroids/organoids. We demonstrated that these cultures, such as the ones resembling the cerebral cortex, can be reliably derived across many lines and experiments, contain synaptically connected neurons and non-reactive astrocytes, and can be used to gain mechanistic insights into genetic and environmental brain disorders. Moreover, when maintained as long-term cultures, they recapitulate an intrinsic program of maturation that progresses towards postnatal stages.
We also pioneered a modular system to integrate 3D brain region-specific organoids and study human neuronal migration and neural circuit formation in functional preparations that we named assembloids. We have actively applied these models in combination with studies in long-term ex vivo brain preparations to acquire a deeper understanding of human physiology, evolution and disease mechanisms.
We have carved a unique research program that combines rigorous in vivo and in vitro neuroscience, stem cell and molecular biology approaches to construct and deconstruct previously inaccessible stages of human brain development and function in health and disease.
We believe science is a community effort, and accordingly, we have been advancing the field by broadly and openly sharing our technologies with numerous laboratories around the world and organizing the primary research conference and the training courses in the area of cellular models of the human brain. -
Michele Lanpher Patel
Instructor, Medicine - Stanford Prevention Research Center
BioMichele L. Patel, PhD is an Instructor in the Stanford University School of Medicine. Her research focuses on optimizing digital health interventions for treating & preventing obesity. Digital interventions have potential for serving as first-line obesity treatments given their accessibility, low cost, and personalization. Dr. Patel is interested in testing innovative strategies to enhance engagement in these digital interventions. Leveraging an 'intervention optimization' paradigm (the Multiphase Optimization Strategy, MOST), she examines the unique and combined weight loss effects of intervention strategies. Optimizing interventions facilitates maximizing clinical impact while minimizing patient burden and healthcare costs.
Dr. Patel received a career development award from NIH (K23; 2022-2027). This work investigates the most potent combination of self-monitoring strategies in a behavioral weight loss intervention for 176 adults with overweight or obesity. Dr. Patel is interested in using digital tools such as commercial apps, wearable devices, and text messaging to improve access to and engagement in treatment.
Dr. Patel received her BA in psychology from Duke University in 2010 and her PhD in clinical psychology from Duke in 2018. She completed her clinical internship at the VA Palo Alto, specializing in behavioral medicine, and her postdoctoral fellowship at the Stanford Prevention Research Center.
Primary Research Interests:
-- Conducting clinical trials to optimize & evaluate digital health interventions for obesity
-- Improving engagement in self-monitoring and other behavioral intervention strategies
-- Identifying psychosocial factors (e.g., health literacy, stress) that impact treatment success
Methods:
-- RCTs, including factorial designs
-- embedded trials (study-within-a-trial)
-- systematic reviews
-- signal detection analysis
-- mixed methods & qualitative methods
