School of Engineering
Showing 481-500 of 689 Results
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Rebecca Pinals
Assistant Professor of Chemical Engineering
BioThe brain is a fascinatingly complex and delicate system of biomolecules, cells, and dynamic interactions that must be carefully maintained to support human health. When this balance is disrupted, disease can arise. Neurodegenerative dementias including Alzheimer’s disease are highly prevalent and profoundly devastating, yet remain largely untreatable or incurable.
The Pinals Lab engineers neuro-models and nano-tools to uncover mechanisms of neurodegenerative disease and intervene to halt—and even reverse—disease progression. A particular emphasis of our work is on the blood–brain barrier (BBB), the vascular interface that serves as the molecular gateway into the brain. We leverage human induced pluripotent stem cells (iPSCs) to build 3D cellular systems, providing a platform to recapitulate human brain properties and pathologies. In parallel, we design nanoparticles to report on real-time neurochemical processes, enabling unprecedented access to dynamic and spatially resolved biomolecular phenomena, and to modulate disease states. By integrating advanced human brain tissue models with rationally designed nanotechnologies, we aim to generate fundamental insights and tools that translate into meaningful impacts for human health. -
Peter Pinsky
Professor of Mechanical Engineering, Emeritus
BioPinsky works in the theory and practice of computational mechanics with a particular interest in multiphysics problems in biomechanics. His work uses the close coupling of techniques for molecular, statistical and continuum mechanics with biology, chemistry and clinical science. Areas of current interest include the mechanics of human vision (ocular mechanics) and the mechanics of hearing. Topics in the mechanics of vision include the mechanics of transparency, which investigates the mechanisms by which corneal tissue self-organizes at the molecular scale using collagen-proteoglycan-ion interactions to explain the mechanical resilience and almost perfect transparency of the tissue and to provide a theoretical framework for engineered corneal tissue replacement. At the macroscopic scale, advanced imaging data is used to create detailed models of the 3-D organization of collagen fibrils and the results used to predict outcomes of clinical techniques for improving vision as well as how diseased tissue mechanically degrades. Theories for mass transport and reaction are being developed to model metabolic processes and swelling in tissue. Current topics in the hearing research arena include multiscale modeling of hair-cell mechanics in the inner ear including physical mechanisms for the activation of mechanically-gated ion channels. Supporting research addresses the mechanics of lipid bilayer cell membranes and their interaction with the cytoskeleton. Recent past research topics include computational acoustics for exterior, multifrequency and inverse problems; and multiscale modeling of transdermal drug delivery. Professor Pinsky currently serves as Chair of the Mechanics and Computation Group within the Department of Mechanical Engineering at Stanford.
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Grigore Pintilie
Research Scientist
BioYork University, B.Sc. 1995-1999, Computer Science - Computer Graphics, HCI
University of Toronto, M.Sc. 1999-2001, Computer Science, Computer Graphics
Blueprint Initiative, 2001-2005 - Bioinformatics Research
MIT, Ph.D. 2005-2011 - Electrical Engineering and Computer Science, Biology - CryoEM map segmentation and fitting of atomic models
Baylor College of Medicine 2011-2017 - Scientific Programmer - Cryo-EM map analysis and atomic modeling
Stanford University 2017-present - Research Scientist - Cryo-EM map analysis and atomic modeling -
Serge Plotkin
Associate Professor of Computer Science, Emeritus
BioPlotkin's focus is on optimization problems that are encountered in the context of design, management, and maintenance of broadband communication networks. Currently his main effort in this area is concentrated on development of algorithms for network topology design, routing, capacity sizing, server placement, and fair resource allocation. His goal is to develop both offline strategies that can be used during network design stage, as well as online strategies that can be applied to optimize existing network infrastructure.
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Jim Plummer
John M. Fluke Professor of Electrical Engineering, Emeritus
Current Research and Scholarly InterestsGenerally studies the governing physics and fabrication technology of silicon integrated circuits, including the scaling limits of silicon technology, and the application of silicon technology outside traditional integrated circuits, including power switching devices such as IGBTs. Process simulation tools like SUPREM for simulating fabrication. Recent work has focused on wide bandgap semiconductor materials, particularly SiC and GaN, for power control devices.
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Kilian M Pohl
Professor (Research) of Psychiatry and Behavioral Sciences (Major Labs and Incubator) and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsThe foundation of the laboratory is computational science aimed at identifying biomedical phenotypes improving the mechanistic understanding, diagnosis, and treatment of neuropsychiatric disorders. The biomedical phenotypes are discovered by unbiased, machine learning-based searches across biological, neuroimaging, and neuropsychological data. This data-driven discovery currently supports the adolescent brain research of the NIH-funded National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA). The laboratory also investigates brain patterns specific to alcohol use disorder, depression, and the human immunodeficiency virus (HIV) across the adult age range, and have advanced the understanding of a variety of brain diseases including schizophrenia, Alzheimer’s disease, glioma, and aging.
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Ada Poon
Associate Professor of Electrical Engineering
Current Research and Scholarly InterestsOur research focuses on providing theoretical foundations and engineering platforms for realizing electronics that seamlessly integrate with the body. Such systems will allow precise recording or modulation of physiological activity, for advancing basic scientific discovery and for restoring or augmenting biological functions for clinical applications.
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Eric Pop
Pease-Ye Professor, Professor of Electrical Engineering, Senior Fellow at the Precourt Institute for Energy and Professor, by courtesy, of Materials Science and Engineering and of Applied Physics
Current Research and Scholarly InterestsThe Pop Lab explores problems at the intersection of nanoelectronics and nanoscale energy conversion. These include fundamental limits of current and heat flow, energy-efficient transistors and memory, and energy harvesting via thermoelectrics. The Pop Lab also works with novel nanomaterials like carbon nanotubes, graphene, BN, MoS2, and their device applications, through an approach that is experimental, computational and highly collaborative.
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J David Powell
Professor of Aeronautics and Astronautics and of Mechanical Engineering, Emeritus
BioEDUCATION:
1960 - B.S. Mechanical Engineering, M.I.T.
1966 - M.S. Aeronautics & Astronautics, Stanford
1970 - Ph.D. Aeronautics & Astronautics, Stanford
EXPERIENCE:
1960-1961 - Engine Design and Testing Engineer at Outboard Marine Corp.
1961-1967 – Engineer at Lockheed in the field of Aerospace Guidance and Control
1967-1968 – Engineer at Analytical Mechanics Associates
1968-1970 – Engineer, Systems Control, Inc. Parameter ID of aircraft models from flight data, automatic generation of approach paths for Air Traffic Control. Attended Stanford University specializing in control systems.
1971 – 1998 – Member of the Stanford Faculty in the Aeronautics and Astronautics Department. His research has included spacecraft pointing, space tether dynamics and control, internal combustion engine control, the design of aerospace digital flight control systems, GPS-based attitude determination augmented with inertial sensors, and the use of GPS for air and land vehicle surveillance and navigation. He taught courses in aerospace control including radio and inertial navigation, optimization and digital implementations and is a coauthor of two of the leading control textbooks. He is also an author or coauthor on over 100 papers.
1998 – present – Emeritus faculty carrying out research in Aeronautics and Astronautics at Stanford Univ. Recent focus of research is the use of GPS-based attitude determination augmented with inertial sensors, applications of the FAA’s WAAS for enhanced pilot displays, flight inspection of aircraft landing systems, and the use of WAAS and new displays to enable closer spacing of parallel runways.
SOCIETY MEMBERSHIPS
AIAA (Fellow), ASME (Fellow), SAE, IEEE, ION
CONSULTANT TO: (over past several years)
Seagull Technology
Sequoia Instruments
Engine Control and Monitoring
Transparent Networks
Pratt and Whitney (Technical Advisory Committee)
Sensor Platforms
OTHER RECENT ACTIVITIES
Co-Founder, CEO, and Director of GyroSat Corp. 1999 – 2000
Director of Sequoia Instruments, 2001 – 2005
Aircraft owner and licensed instrument pilot
National Research Council Panel member for the review of NASA airspace activities, 2003
Board of Directors, Mechanics Bank, Richmond, CA., 2003 – 2015
Board of Directors, ExactBid, Inc. 2014-present. -
Balaji Prabhakar
VMware Founders Professor of Computer Science, Professor of Electrical Engineering and, by courtesy, of Operations, Information and Technology at the Graduate School of Business
BioPrabhakar's research focuses on the design, analysis, and implementation of data networks: both wireline and wireless. He has been interested in designing network algorithms, problems in ad hoc wireless networks, and designing incentive mechanisms. He has a long-standing interest in stochastic network theory, information theory, algorithms, and probability theory.
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Manu Prakash
Associate Professor of Bioengineering, Senior Fellow at the Woods Institute for the Environment and Associate Professor, by courtesy, of Oceans
BioWe use interdisciplinary approaches including theory and experiments to understand how computation is embodied in biological matter. Examples include cognition in single cell protists and morphological computing in animals with no neurons and origins of complex behavior in multi-cellular systems. Broadly, we invent new tools for studying non-model organisms with significant focus on life in the ocean - addressing fundamental questions such as how do cells sense pressure or gravity? Finally, we are dedicated towards inventing and distributing “frugal science” tools to democratize access to science (previous inventions used worldwide: Foldscope, Abuzz), diagnostics of deadly diseases like malaria and convening global citizen science communities to tackle planetary scale environmental challenges such as mosquito surveillance or plankton surveillance by citizen sailors mapping the ocean in the age of Anthropocene.
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Friedrich Prinz
Leonardo Professor, Professor of Mechanical Engineering, of Materials Science and Engineering and Senior Fellow at the Precourt Institute for Energy
BioFritz Prinz is the Leonardo Professor in the School of Engineering at Stanford University, Professor of Materials Science and Engineering, Professor of Mechanical Engineering, and Senior Fellow at the Precourt Institute for Energy. He also serves as the Director of the Nanoscale Prototyping Laboratory and Faculty Co-director of the NPL-Affiliate Program. A solid-state physicist by training, Prinz leads a group of doctoral students, postdoctoral scholars, and visiting scholars who are addressing fundamental issues on energy conversion and storage at the nanoscale. In his Laboratory, a wide range of nano-fabrication technologies are employed to build prototype fuel cells and capacitors with induced topological electronic states. We are testing these concepts and novel material structures through atomic layer deposition, scanning tunneling microscopy, impedance spectroscopy and other technologies. In addition, the Prinz group group uses atomic scale modeling to gain insights into the nature of charge separation and recombination processes. Before coming to Stanford in 1994, he was on the faculty at Carnegie Mellon University. Prinz earned a PhD in Physics at the University of Vienna.
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Patrick Lee Purdon
Professor of Anesthesiology, Perioperative and Pain Medicine (Department Research) and, by courtesy, of Bioengineering
BioMy research integrates neuroimaging, biomedical signal processing, and the systems neuroscience of general anesthesia and sedation.
My group conducts human studies of anesthesia-induced unconsciousness, using a variety of techniques including multimodal neuroimaging, high-density EEG, and invasive neurophysiological recordings used to diagnose medically refractory epilepsy. We also develop novel methods in neuroimaging and biomedical signal processing to support these studies, as well as methods for monitoring level of consciousness under general anesthesia using EEG. -
Lei (Stanley) Qi
Associate Professor of Bioengineering
BioDr. Lei (Stanley) Qi (publishes as Lei S. Qi) is an Associate Professor in the Department of Bioengineering at Stanford University, an Institute Scholar at Sarafan ChEM-H, and a Chan Zuckerberg Biohub Investigator. Trained in physics and mathematics (Tsinghua University) and bioengineering (UC Berkeley), he was a Systems Biology Fellow at UCSF before joining the Stanford faculty in 2014.
Qi is a pioneer in CRISPR technology and genome engineering. His lab created the first nuclease-deactivated Cas9 (dCas9) for targeted gene regulation, establishing CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa). Since then, his group has expanded CRISPR from an editing tool into a platform for programmable control of dynamic and spatial cell state, integrating scalable perturbation, live-cell and super-resolution imaging, and computation-guided design. This work has produced technologies for multiplexed transcriptome regulation, programmable 3D genome organization, spatial RNA logistics control, and real-time visualization of chromatin and transcriptional events in living cells.
A distinctive focus of the Qi lab is closed-loop biology, combining perturbation with high-content measurements to infer mechanisms and iteratively refine control strategies. The lab develops platforms spanning multiplexed transcriptional and epigenetic control, spatial genome–transcriptome organization, and quantitative live-cell imaging of chromatin and transcriptional dynamics. A compact nuclease-dead CRISPR epigenetic editor from this technology lineage has advanced to first-in-human clinical testing for facioscapulohumeral muscular dystrophy (FSHD; NCT06907875), underscoring the translational potential of principle-driven control systems.
Beyond single-cell control, Qi’s lab is building a framework for synthetic cell–cell communication, with particular emphasis on the bidirectional interplay between immune cells and neurons. The lab’s goal is to move beyond describing molecular parts to discovering fundamental control principles in living systems: how regulatory landscapes create stable states and memory, how spatial genome–RNA organization shapes dynamic responses, and how engineered cell–cell interactions can generate emergent multicellular behaviors. By integrating experimental bioengineering with computation and machine learning, the lab aims to identify generalizable rules linking molecular programs to systems-level physiology and disease trajectories and to translate those rules into next-generation therapeutic cells. -
Jian Qin
Associate Professor of Chemical Engineering
BioJian Qin is an Associate Professor in the Department of Chemical Engineering at the Stanford University. His research focuses on development of microscopic understanding of structural and physical properties of soft matters by using a combination of analytical theory, scaling argument, numerical computation, and molecular simulation. He worked as a postdoctoral scholar with Juan de Pablo in the Institute for Molecular Engineering at the University of Chicago and with Scott Milner in the Department of Chemical Engineering at the Pennsylvania State University. He received his Ph.D. in the Department of Chemical Engineering and Materials Science at the University of Minnesota under the supervision of David Morse and Frank Bates. His research covers self-assembly of multi-component polymeric systems, molecular origin of entanglement and polymer melt rheology, coacervation of polyelectrolytes, Coulomb interactions in dielectrically heterogeneous electrolytes, and surface charge polarizations in particulate aggregates in the absence or presence of flow.
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Xiaojie Qiu
Assistant Professor of Genetics and, by courtesy, of Computer Science
Current Research and Scholarly InterestsAt the Qiu Lab, our mission is to unravel and predict the intricacies of gene regulatory networks and cell-cell interactions pivotal in mammalian cell fate transitions over time and space, with a special emphasis on heart evolution, development, and disease. We are a dynamic and interdisciplinary team, harnessing the latest advancements in machine learning as well as single-cell and spatial genomics by integrating the predictive power of systems biology with the scalability of machine learning,
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Stephen Quake
Lee Otterson Professor in the School of Engineering and Professor of Bioengineering, of Applied Physics and, by courtesy, of Physics
Current Research and Scholarly InterestsSingle molecule biophysics, precision force measurement, micro and nano fabrication with soft materials, integrated microfluidics and large scale biological automation.
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Priyanka Raina
Associate Professor of Electrical Engineering and, by courtesy, of Computer Science
Current Research and Scholarly InterestsFor Priyanka's research please visit her group research page at https://stanfordaccelerate.github.io
