School of Humanities and Sciences
Showing 101-110 of 133 Results
-
Andrew Spakowitz
Tang Family Foundation Chair of the Department of Chemical Engineering, Professor of Chemical Engineering, of Materials Science and Engineering and, by courtesy, of Applied Physics
Current Research and Scholarly InterestsTheory and computation of biological processes and complex materials
-
Daniel Stack
Associate Professor of Chemistry
BioResearch in the Stack group focuses on the mechanism of dioxygen activation and the subsequent oxidative reactivity with primarily copper complexes ligated by imidazoles or histamines. Specifically, the group is interested in substrate hydroxylations and full dioxygen reduction. The remarkable specificity and energy efficiency of metalloenzymes provide the inspiration for the work. Trapping and characterizing immediate species, primarily at low temperatures, provide key mechanistic insights especially through substrate reactivity along with spectroscopic and metrical correlation to DFT calculations. Our objective is to move these efficient enzymatic mechanisms into small synthetic complexes, not only to reproduce biological reactivity, but more importantly to move the oxidative mechanism beyond that possible in the protein matrix.
Daniel Stack was born, raised and attended college in Portland Oregon. He received his B.A. from Reed College in 1982 (Phi Beta Kappa), working with Professor Tom Dunne on weak nickel-pyrazine complexes. In Boston, he pursued his doctoral study in synthetic inorganic chemistry at Harvard University (Ph.D., 1988) with Professor R. H. Holm, investigating site-differentiated synthetic analogues of biological Fe4S4 cubanes. As an NSF Postdoctoral Fellow with Professor K. N. Raymond at the University of California at Berkeley, he worked on synthesizing new, higher iron affinity ligands similar to enterobactin, a bacterial iron sequestering agent. He started his independent career in 1991 at Stanford University primarily working on oxidation catalysis and dioxygen activation, and was promoted to an Associate Professor in 1998. His contributions to undergraduate education have been recognized at the University level on several occasions, including the Dinkelspiel Award for Outstanding Contribution to Undergraduate Education in 2003.
Areas of current focus include:
Copper Dioxygen Chemistry
Our current interests focus on stabilizing species formed in the reaction of dioxygen with Cu(I) complexes formed with biologically relevant imidazole or histamine ligation. Many multi-copper enzymes ligated in this manner are capable of impressive hydroxylation reactions, including oxidative depolymerization of cellulose, methane oxidation, and energy-efficient reduction of dioxygen to water. Oxygenation of such complexes at extreme solution temperatures (-125°C) yield transient Cu(III) containing complexes. As Cu(III) is currently uncharacterized in any biological enzyme, developing connections between the synthetic and biological realms is a major focus.
Surface Immobilization of Catalysts in Mesoporous Materials
In redox active biological metal sites, the ligation environment is coupled tightly to the functional chemistry. Yet, the metal sites are also site-isolated, creating species that may only have a transient existence in a homogeneous solution. Site isolation of synthetic complexes can be achieved synthetically by supporting the metal complex on a solid matrix. Movement of these complexes into silica based materials or onto electroactive carbon electrodes represent a new direction for the group in the development of bio-inspired metal-based catalysts. -
Kathryn Starkey
Edward Clark Crossett Professor of Humanistic Studies and Professor, by courtesy, of English, of History and of Comparative Literature
BioKathryn Starkey is Professor of German in the Department of German Studies and, by courtesy, Professor of English, History, and Comparative Literature. Her work focuses primarily on medieval German literature from the eleventh to the thirteenth century, and her research topics encompass visuality and materiality, object/thing studies, manuscript illustration and transmission, language, performativity, and poetics. She has held visiting appointments at the Universities of Palermo (2011) and Freiburg im Breisgau (2013 and 2018).
Recent book publications (since 2012) include:
* Things and Thingness in European Literature and Visual Art, 800-1600, edited with Jutta Eming (Berlin/New York, 2021).
* Animals in Text and Textile. Storytelling in the Medieval World, edited with Evelin Wetter. Riggisberger Berichte, Vol. 24 (Riggisberg, Switzerland, 2019).
* Sensory Reflections. Traces of Experience in Medieval Artifacts, edited with Fiona Griffiths (Berlin/New York, 2018).
* Neidhart: Selected Songs from the Riedegger Manuscript, edited and translated with Edith Wenzel, TEAMS series in bilingual medieval German texts (Kalamazoo, MI, 2016).
* A Courtier’s Mirror: Cultivating Elite Identity in Thomasin von Zerclaere’s “Welscher Gast” (Notre Dame, 2013).
* Visuality and Materiality in the Story of Tristan, edited with Jutta Eming and Ann Marie Rasmussen (Notre Dame, 2012).
Professor Starkey is the PI for the Global Medieval Sourcebook (https://sourcebook.stanford.edu/) for which she received a NEH Digital Humanities Advancement Grant (2018) as well as awards from the Roberta Bowman Denning Fund for Humanities and Technologies at Stanford (2016, 2017, 2018).
Her current research projects include a co-authored (with Fiona Griffiths) textbook for the Cambridge Medieval Textbook series on A History of Medieval Germany (900-1220).
Professor Starkey has been the recipient of fellowships from the National Humanities Center, the Alexander von Humboldt Foundation, the UNC Institute for the Arts and the Humanities, and the Social Sciences and Humanities Research Council of Canada (SSHRCC).
Before joining the faculty at Stanford in 2012 she taught in the Department of Germanic and Slavic Languages and Literatures at the University of North Carolina at Chapel Hill.
