Institute for Stem Cell Biology and Regenerative Medicine
Showing 131-140 of 153 Results
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Ayelet Voskoboynik
Assistant Professor (Research) of Biology
Current Research and Scholarly InterestsWe study the mechanisms by which animals differentiate between self and non-self, and how stem cells and immune cells coordinate to form tissues during development, regeneration, transplantation, and aging. By leveraging the natural stem cell-mediated development, regeneration, and chimerism in the colonial chordate Botryllus schlosseri, we investigate stem cell competition and the decline in regenerative capacity during aging.
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Li Wang
Assistant Professor of Biology
Current Research and Scholarly InterestsWe study how the extraordinary diversity of cells and synapses in the brain is generated, organized, and maintained, and how these processes are disrupted in diseases such as neurodevelopmental disorders and brain cancer. By combining single-cell and spatial genomics, lineage tracing, perturbation screens, synaptic proteomics, and machine learning models, we aim to uncover the molecular rules that define neural identity and connectivity.
Our research spans two interrelated themes, each grounded in human biology and driven by cutting-edge technologies. By comparing these processes across species, we aim to uncover both conserved mechanisms and human-specific innovations that define the unique features of the human brain. -
Irving Weissman
Virginia & D.K. Ludwig Professor of Clinical Investigation in Cancer Research, Professor of Pathology, and of Developmental Biology
Current Research and Scholarly InterestsStem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis; order of events from hematopoietic stem cells [HSC] to AML leukemia stem cells and blood diseases, and parallels in other tissues; discovery of tumor and pathogenic cell 'don't eat me' and 'eat me' signals, and translation into therapeutics.
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Gerlinde Wernig
Associate Professor of Pathology
Current Research and Scholarly InterestsFibrotic diseases kill more people than cancer in this country and worldwide. We believe that scar-forming cells called fibroblasts are at the core of the fibrotic response in parenchymal organ fibrosis in the lung, liver, skin, bone marrow and tumor stroma. At the cellular level we think of fibrosis as a step wise process which implicates inflammation and fibrosis. We seek to identify new effective immune therapy targets to treat fibrotic diseases.
