School of Medicine
Showing 301-350 of 774 Results
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Pik Fang Kho
Postdoctoral Scholar, Cardiovascular Medicine
BioI obtained my PhD in genetic epidemiology at Queensland University of Technology (Australia), where my research was focused on using genetic and genomic approaches to identify risk factors for endometrial cancer. During my graduate studies, I gained experience in large-scale genetic association studies and leveraging the correlation between diseases in genetic studies to identify novel genetic variants associated with endometrial cancer. I also developed expertise in various statistical genetic approaches in multi-omics data, including fine-mapping and colocalization analyses, to prioritize candidate causal variants and genes. I also gained extensive experience in genetic causal inference analysis to infer causality between risk factors and health outcomes.
My research focus since moving to Stanford has been the identification of genetic and non-genetic determinants of cardiometabolic diseases. I am currently involved in projects including large-scale genetic association studies, multi-trait analysis with correlated traits, development and validation of polygenic risk scores, integrative analyses with multi-omics data, as well as Mendelian randomization analyses to advance our understanding of the genetic and environmental factors that contribute to cardiometabolic diseases. -
Abbas Khojasteh
Postdoctoral Scholar, Neurology and Neurological Sciences
BioHis current medical study and research at Stanford is directed towards applying early detection strategies to the treatment of brain tumors and reversing the damaging side effects of treatment-related brain injury. He received his Ph.D from Zurich University and completed postdoctoral neurosurgery training at Duke University where he was studying experimental models of neuro modulation of glycemia and immune system in infectious diseases and inflammatory disorders. He evaluated the Electrical modulation efficacy in ongoing inflammation and hyperglicemia under different conditions, such as somatotopy organizations, disease states and intensities (electrical current/potential); and he recognized different neuro fibers controlling inflammation and glycemia networks. He pushed further his idea to find out whether regulation of glycemia and inflammation by electricity is dependent on central processing and to discover a new mechanism controlling insulin production. For this novel study, he performed Spinal Cord surgery. Also, as a bioengineer, his previous research focused on drug discovery, cell biology and cell cultivation techniques for optimization of growth and bioengineering parameters in bioreactors. He has experience in expression of therapeutic antibodies and production of secondary metabolites in mammalian and plant cell cultivations for therapeutics and diagnostics aims.
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Chaitan Khosla
Wells H. Rauser and Harold M. Petiprin Professor and Professor of Chemistry and, by courtesy, of Biochemistry
Current Research and Scholarly InterestsResearch in this laboratory focuses on problems where deep insights into enzymology and metabolism can be harnessed to improve human health.
For the past two decades, we have studied and engineered enzymatic assembly lines called polyketide synthases that catalyze the biosynthesis of structurally complex and medicinally fascinating antibiotics in bacteria. An example of such an assembly line is found in the erythromycin biosynthetic pathway. Our current focus is on understanding the structure and mechanism of this polyketide synthase. At the same time, we are developing methods to decode the vast and growing number of orphan polyketide assembly lines in the sequence databases.
For more than a decade, we have also investigated the pathogenesis of celiac disease, an autoimmune disorder of the small intestine, with the goal of discovering therapies and related management tools for this widespread but overlooked disease. Ongoing efforts focus on understanding the pivotal role of transglutaminase 2 in triggering the inflammatory response to dietary gluten in the celiac intestine. -
Butrus Khuri-Yakub
Professor (Research) of Electrical Engineering, Emeritus
BioButrus (Pierre) T. Khuri-Yakub is a Professor of Electrical Engineering at Stanford University. He received the BS degree from the American University of Beirut, the MS degree from Dartmouth College, and the Ph.D. degree from Stanford University, all in electrical engineering. His current research interests include medical ultrasound imaging and therapy, ultrasound neuro-stimulation, chemical/biological sensors, gas flow and energy flow sensing, micromachined ultrasonic transducers, and ultrasonic fluid ejectors. He has authored over 600 publications and has been principal inventor or co-inventor of 107 US and international issued patents. He was awarded the Medal of the City of Bordeaux in 1983 for his contributions to Nondestructive Evaluation, the Distinguished Advisor Award of the School of Engineering at Stanford University in 1987, the Distinguished Lecturer Award of the IEEE UFFC society in 1999, a Stanford University Outstanding Inventor Award in 2004, Distinguished Alumnus Award of the School of Engineering of the American University of Beirut in 2005, Stanford Biodesign Certificate of Appreciation for commitment to educate, mentor and inspire Biodesgin Fellows, 2011, and 2011 recipient of IEEE Rayleigh award.
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Kiran Kaur Khush, MD
Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsDr. Khush's clinical research interests include the evaluation of donors and recipients for heart transplantation; mechanisms of adverse outcomes after heart transplantation, including cardiac allograft vasculopathy and antibody-mediated rejection; and development of non-invasive diagnostic approaches for post-transplant monitoring.
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Phuong Khuu, MD
Clinical Assistant Professor, Dermatology
BioPhuong Khuu, M.D., is a Clinical Assistant Professor in Pediatric Dermatology at Lucile Packard Children’s Hospital. Her clinical interests include children with complex dermatologic diseases and epidermolysis bullosa. Her research interest is in clinical management of epidermolysis bullosa.
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Mathew Kiang
Assistant Professor of Epidemiology and Population Health (Epidemiology)
BioI am an assistant professor in the Department of Epidemiology and Population Health. My research lies at the intersection of computational epidemiology and social epidemiology. Methodologically, my work revolves around combining disparate data sources in epidemiologically meaningful ways. For example, I work with individual-level, non-health data (e.g., GPS, accelerometer, and other sensor data from smartphones), traditional health data (e.g., survey, health systems, or death certificate data), and third-party data (e.g., cellphone providers or ad-tech data). To do this, I use a variety of methods such as joint Bayesian spatial models, traditional epidemiologic models, dynamical models, microsimulation, and demographic analysis. Substantively, my work focuses on socioeconomic and racial/ethnic inequities. For example, recently, my work has examined inequities in COVID-19 vaccine distribution, cause-specific excess mortality, and drug poisonings. I have an NIDA-funded R00 examining equitable ways to improve treatment for opioid use disorder across structurally disadvantaged groups and am Co-I on a NIDA-funded R21 examining ways to use novel data sources (such as social media) to predict surges in opioid-related mortality.
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Nour Kibbi, MD, FAAD
Clinical Assistant Professor, Dermatology
BioDr. Kibbi is a board-certified dermatologist and fellowship-trained dermatologic surgeon. Her clinical interests include Mohs micrographic surgery for skin cancer and laser and injectable treatments to combat aging, sun-damaged skin, and other indications. Her research interests include rare skin tumors, challenging lip lesions, non-invasive treatments, such as photodynamic therapy for non-melanoma skin cancer, and cosmetic procedures for acne scars and autoimmune conditions. Her work has appeared at national and international meetings and has been published in peer-reviewed journals, including Lancet Oncology, Journal of the American Academy of Dermatology, British Journal of Dermatology, Journal of Dermatologic Surgery.
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Melanie Ann Kiener
Postdoctoral Medical Fellow, Infectious Diseases
BioI am an adult infectious disease fellow completing my post-doctoral research years in Dr. Desiree LaBeaud's lab. My research interests include global health epidemiology, infectious diseases diagnostics and global antimicrobial stewardship.
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Michaela Kiernan
Sr Res Scholar, Medicine - Med/Stanford Prevention Research Center
Current Research and Scholarly InterestsResearch interests include: (1) the design and testing of targeted behavioral interventions that promote long-term lifestyle changes and weight management among subgroups at risk, and (2) the development of methodological and statistical approaches that improve the design, delivery, and analysis of behavioral randomized clinical trials
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James Michael Kilgour
Affiliate, Department Funds
Resident in DermatologyBioJames grew up in Oxford in the United Kingdom. He graduated from Cardiff University School of Medicine with honours in 2017, and has a BSc in Medical Education. Following graduation, he completed two years as a clinical academic in Dermatology at the University of Oxford, conducting research investigating patient-reported outcome measures and quality of life in patients with Graft-versus-Host-Disease following allogenic stem cell transplant. He subsequently completed a two year precision medicine fellowship at the Stanford University Department of Dermatology, focusing on cutaneous oncology and hidradenitis suppurativa. He has also extensively published in medical education, and co-founded a novel peer reviewed medical journal targeted at encouraging medical students to publish and peer review. He is currently completing his residency in Dermatology at Stanford.
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Joel Killen
Professor (Research) of Medicine (General Internal Medicine), Emeritus
Current Research and Scholarly InterestsMy research is focused on the development and evaluation of cigarette smoking prevention and cessation therapies and obesity prevention treatments for children, adolescents and adults.
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Daniel Kim
Clinical Associate Professor, Psychiatry and Behavioral Sciences
BioDr. Daniel Kim is a board-certified geriatric psychiatrist who serves as medical director of the inpatient geriatric psychiatry service and program director of the geriatric psychiatry fellowship. His primary area of interest is in the education of medical students, residents, and fellows in geriatric psychiatry.
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Dan Seung Kim, MD, PhD, MPH
Fellow in Graduate Medical Education
Current Research and Scholarly InterestsMy research projects within the laboratory of Euan Ashley center around the broad topic of exercise, physiology, and cardiovascular disease:
1. Digital health interventions - I previously have published on the topic of digital health interventions delivered via an iPhone app (Kim and Javed et al, European Heart Journal - Digital Health 2023). We found that personalizing interventions based on individual's baseline activity was more effective in increasing short-term physical activity than other "one-size fits all" approaches. In our next phase, we will extend this to under-represented populations in digital health and implement cutting-edge artificial intelligence models to improve our interventions.
2. Molecular mechanisms of exercise physiologic adaptations - using time-series multi-omic data, we aim to map out the molecular responses to endurance exercise training in rats, using data from the Molecular Transducers of Physical Activity Consortium (MoTrPAC). See our recent review in Nature Reviews Genetics - Kim et al, 2021.
3. Effect of physical activity on coronary artery disease symptoms and outcomes - in collaboration with Dr David Maron and the ISCHEMIA study, I am investigating the effects of physical activity and sedentary behavior on symptoms related to known coronary heart disease and separately, the outcome of all-cause mortality.
4. Exercise [hysiology - in collaboration with Dr Francois Haddad and Dr Jonathan Myers, I am working on projects to better standardize reporting of maximal oxygen uptake. In brief, maximal oxygen uptake (VO2 max) is an extremely valuable prognostic, but estimation of this physiologic value is poor in certain populations. We are working to improve estimation of this variable and demonstrating its efficacy in predicting hard outcomes in patients with heart failure.
5. Outcomes in inherited cardiomyopathies - under the mentorship of Dr Euan Ashley, I am building my clinical expertise in treating patients with inherited cardiomyopathies. The Stanford Center for Inherited Cardiovascular Disease (SCICD) is home to clinical care of patients with inherited cardiomyopathies, channelopathies, inherited lipid disorders, neuromuscular disorders (e.g., muscular dystrophy), and vascular disorders (e.g., Marfan's and other aorthopathies). Our clinic is nested within the Heart Failure program and manages those patients who are progressing toward advanced heart failure therapies, such as transplant or left ventricular assist devices. Within this clinic, I am leading projects to describe our experience with mavacamten, a first of its class treatment of hypertrophic cardiomyopathy with obstruction.