School of Medicine
Showing 1-50 of 83 Results
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Heather Wakelee
Professor of Medicine (Oncology)
Current Research and Scholarly InterestsDr. Wakelee's research is focused on clinical trials and translational efforts in patients with lung cancer and other thoracic malignancies such as thymoma and thymic carcinoma. Other interests include translation projects in thoracic malignancies and collaborations with population scientists regarding lung cancer questions.
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Paul J. Wang, MD
John R. and Ai Giak L. Singleton Director, Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Bioengineering
Current Research and Scholarly InterestsDr. Wang's research centers on the development of innovative approaches to the treatment of arrhythmias, including more effective catheter ablation techniques, more reliable implantable devices, and less invasive treatments. Dr. Wang's clinical research interests include atrial fibrillation, ventricular tachycardia, syncope, and hypertrophic cardiomyopathy. Dr. Wang has active collaborations with Bioengineering, Mechanical Engineering, and Electrical Engineering Departments at Stanford.
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Taia T. Wang, MD, PhD, MSCI
Assistant Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsLaboratory of Mechanisms in Human Immunity and Disease Pathogenesis
Studies in our lab are aimed at defining mechanisms in human immunity and disease. We are particularly interested the hypothesis that diversity in antibody-based signaling that arises from diversity in IgG antibodies and their receptors, is a central driver of heterogeneity in human immune functioning and susceptibility to infectious diseases. We are studying how the Fc domain repertoire of an individual impacts the quality of effector cell responses that can be recruited during immune activation and how selectivity of effector responses contributes to immunity and disease.
SARS-CoV-2, dengue viruses, influenza viruses, disease pathogenesis, influenza vaccines
Current clinical studies:
Recruiting:
An Open Label Study of IgG Fc Glycan Composition in Human Immunity
Principal Investigator: Taia T. Wang, MD, PhD
ClinicalTrials.gov Identifier:
NCT01967238 -
Brian Wayda
Postdoctoral Scholar, Cardiovascular Medicine
Current Research and Scholarly InterestsHeart transplant policy and outcomes, cost-effectiveness, mathematical modeling
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Ann Weinacker
Professor of Medicine (Pulmonary and Critical Care)
Current Research and Scholarly InterestsDr. Weinacker's research interests center around ICU outcomes. Her specific interests include primary graft dysfunction in lung transplant recipients.
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Eva Weinlander
Clinical Professor, Medicine - Primary Care and Population Health
Current Research and Scholarly InterestsWomen's Health
Mind Body Medicine
Chronic Disease Management -
Chad S. Weldy, M.D., Ph.D.
Postdoctoral Medical Fellow, Cardiovascular Medicine
Fellow in Medicine
Resident in MedicineCurrent Research and Scholarly InterestsAs a physician-scientist in the lab of Dr. Quertermous I work to understand the genetic basis of cardiovascular disease and the transcriptional and epigenomic mechanisms of atherosclerosis. My work is focused across three main areas of cardiovascular genetics and mechanisms of coronary artery disease and smooth muscle biology:
1.CRISPRi screening with targeted perturb seq (TAPseq) to identify novel CAD genes in human coronary artery smooth muscle cells
2.Investigation of the epigenetic and molecular basis of coronary artery disease and smooth muscle cell transition in mice with conditional smooth muscle genetic deletion of CAD genes Pdgfd and Sox9
3.Defining on single cell resolution the cellular and epigenomic features of human vascular disease across vascular beds of differing embryonic origin
My work with Dr. Quertermous is focused on driving discovery in vascular biology by understanding how common genetic variation in humans in complex disease can lead to novel understandings of disease mechanism. With nearly 100,000 GWAS loci discovered across all complex disease, and nearly 300 GWAS loci identified within coronary artery disease, the methods by which GWAS loci are mapped to causal gene is often times limited based proximity to lead SNP without confirmatory functional genomic testing. By using CRISPRi screening in human coronary artery smooth muscle cells with targeted perturb seq (TAPseq), we aim to epigenetically modify specific GWAS loci to then understand enhancer-gene pairs and identify causal CAD genes within the region of a CAD GWAS loci. For identified CAD genes with high confidence for their causality, understanding how CAD genes modify smooth muscle cell state transition within the vascular wall and the epigenomic mechanisms by which this transition occurs is crucial. By using a vascular smooth muscle cell lineage traced mouse model, we can induce smooth muscle specific deletion of CAD genes, Pdgfd and Sox9 to better understand their causal mechanism in vascular disease with single cell RNAseq and single cell ATACseq. Understanding this cell state transition and epigenomic basis of disease is further expanded to human disease with collaboration from our cardiothoracic surgical colleagues. By harvesting human vascular samples at the time of transplant or organ donation, we have the unique ability to understand on a single cell resolution the mechanisms of vascular disease. Importantly, by comparing the cellular gene expression and cell population with scRNAseq in combination with understanding chromatin accessibility on single cell resolution with scATACseq across vascular beds from differing embryonic origin (coronary, ascending aorta, aortic arch, descending thoracic, infrarenal, carotid artery) we can work to understand why there is differential susceptibility to vascular disease across vascular sites and the epigenomic and transcriptional mechanisms that facilitate this differential susceptibility.
This work attempts to apply multiple scientific research arms to ultimately lead to novel understandings of vascular disease and discover important new therapeutic approaches for drug discovery. -
Kirsti Weng Elder MD/MPH
Clinical Associate Professor, Medicine - Primary Care and Population Health
BioDr. Weng is the Section Chief of General Primary Care. She has over 25 years of experience caring for patients in primary care, urgent care and in the hospital. She is also a teacher of students and residents. As a leader in primary care re-design, she is passionate about practicing patient-centered medicine. She is a an advocate of Mindfulness Self-compassion to develop equanimity. She practices with an emphasis on musculoskeletal care as she feels fitness is the foundation of wellness. She is a leader in organizational change and physician management. She supports community health and care for the underserved. Outside of work she enjoys biking, reading and spending time with her 8 children.
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Wen-Kai Weng, MD, PhD
Associate Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy) and, by courtesy, of Dermatology
Current Research and Scholarly InterestsMy research interest is on immunotherapy (including allogeneic transplant) of cancer. I have studies the mechanism of monoclonal antibody therapy in lymphoma patients and am currently working on designing new strategy to enhance the clinical efficacy of antibody therapy by infusing expanded NK cells. I am also interested in using tumor vaccine along with hematopoietic cell transplant.
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Yingjie Weng
Biostatistician 3, Med/Quantitative Sciences Unit
Current Role at StanfordIndependently collaborate with research investigators for a variety types of scientific researches across Stanford Campus
Lead the development of study protocol and statistical analysis plan at the project level
Perform data management, visualization and statistical analysis with the cutting-edge methods and tools
Interpret the results from the statistical reports with appropriate domain languages for publication purposes
Lead the statistical method and/or result sections for grant application and manuscript submissions
Statistical method research
Mentor junior members for statistical analysis -
Cornelia Weyand
Professor of Medicine (Immunology and Rheumatology), Emerita
Current Research and Scholarly InterestsAutoimmunity
Chronic inflammatory disease
Metabolic control of immune function -
Matthew Wheeler
Assistant Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsTranslational research in rare and undiagnosed diseases. Basic and clinical research in cardiomyopathy genetics, mechanisms, screening, and treatment. Investigating novel agents for treatment of hypertrophic cardiomyopathy and new mechanisms in heart failure. Cardiovascular screening and genetics in competitive athletes, disease gene discovery in cardiomyopathy and rare disease. Informatics approaches to rare disease and multiomics. Molecular transducers of physical activity bioinformatics.
