School of Medicine
Showing 1,091-1,100 of 1,458 Results
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Michael J Rosen, MD, MSCI
Stanford University Endowed Professor for Pediatric IBD and Celiac Disease
BioI am a pediatric gastroenterologist and physician scientist, who has been devoted to inflammatory bowel disease (IBD) research since beginning medical training over 20 years ago. I am also Director of the Stanford Center for Pediatric IBD and Celiac Disease. I have expertise crossing mucosal immunology and epithelial biology, formal training and experience in clinical and translational investigation with human biospecimens, and direct insight regarding the important clinical challenges caring for children with complicated IBD. My translational research program focuses on how the immune system regulates epithelial function in chronic intestinal inflammation as it relates to IBD. My clinical research program has focused on optimization of anti-TNF therapy in pediatric IBD, and in particular acute severe ulcerative colitis (ASUC). My laboratory has demonstrated a protective role for IL33, a cytokine that induces type 2 cytokines from T cells an innate lymphoid cells (ILCs), in acute oxazolone colitis through preservation of epithelial goblet cells and barrier function. In line with this finding, we have also shown in a large prospective patient cohort that mucosal expression of type 2 and type 17 immune response genes distinguishes ulcerative colitis (UC) from colon-only Crohn’s disease, and that type 2 gene expression is associated with superior clinical outcome in pediatric UC. We have now developed an organoid-immune cell in vitro culture system to demonstrate the ILC2-dependent mechanism through which IL33 induces goblet cell differentiation in the intestinal epithelium. I led the multicenter study Anti-TNF for Refractory Colitis in Hospitalized Children (ARCH) Study, which aims to establish determinants of anti-TNF response in pediatric ASUC and currently Co-Chair the Crohn's & Colitis Foundations Cohort for Pediatric Translational and Clinical Research in IBD (CAPTURE IBD) and PRO-KIIDS Pediatric IBD clinical research network.
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David Rosenthal
Professor of Pediatrics (Pediatric Cardiology)
Current Research and Scholarly InterestsResearch interests include the study of Heart Failure, Cardiomyopathy and ventricular dysfunction in children, from a clinical perspective. Investigations include clinical trials of medications, cardiac resynchronization, and mechanical circulatory support.
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Charlene Larson Rotandi
Associate Director of Fellowship Education, Pediatrics
BioI am currently the Associate Director of Fellowship Education in the Office of Pediatric Education. Most recently, I was the Department Fellowship Manager for the Department of Pediatrics, and prior to that I was the Fellowship and Postdoctoral Administrator in the Department of Pediatrics, Hematology/Oncology at Stanford University School of Medicine. Other positions I have held included Pediatric Residency Coordinator for Lucile Packard Children’s Hospital at Stanford University and the Graduate Medical Education Coordinator for the Department of OB/GYN and Reproductive Sciences at the University of California, San Francisco.
I am actively engaged in the Association of Pediatric Program Directors (APPD), currently serving on the Mentoring Work Group for the Coordinators’ Executive Committee. I’ve collaborated on a number of scholarly activities with fellow APPD colleagues in the area of professional empowerment and advancement of coordinators, coordinator wellness, program evaluation committees and annual program evaluations, clinical competency committees and milestones, as well as presented a fellow/faculty development workshop on milestones and assessment tools for our division. I continue to seek out opportunities to collaborate, mentor, and take on leadership positions.
Outside of graduate medical education, I am the mother of a very active and curious seven year-old. I also enjoy spending time with my family exploring the Bay Area, hiking, cooking, and enjoying food and wine and the vibrant arts culture. A brief stint as a pastry cook, I love to cook and bake with my son. Additionally, I continue to be involved in my alma mater, Vassar College, by co-chairing the Vassar Alumnae/i Admissions Program in San Francisco. -
Stephen J. Roth
Professor of Pediatrics (Cardiology)
On Partial Leave from 06/17/2024 To 07/31/2024Current Research and Scholarly InterestsRandomized Therapeutic Trials in Pediatric Heart Disease, NIH/U01 GrantNo. HL68285 2001-2006.
Heparin and the Reduction of Thrombosis (HART) Study. Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006.
A Pilot Trial fo B-type Natriuretic Peptide for Promotion of Urine Output in Diuretic-Resistant Infants Following Cardiovascular Surgery.Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006.
