School of Medicine
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Pasqualina Colella
Affiliate, Pediatrics - Genetics
BioDr. Pasqualina Colella is a scientist with expertise in gene and cell therapy for inherited diseases. She is currently a Senior Research Scientist at Stanford University, where she leads translational research on hematopoietic stem cell transplantation (HSCT), microglia replacement, myeloid cell recruitment to the central nervous system, and genome editing. Her goal is to improve treatment outcomes for neurodegenerative lysosomal storage diseases.
Dr. Colella earned her PhD at TIGEM (Italy), where she developed gene therapies for inherited retinal disorders, including dual AAV approaches for large gene delivery targeting Usher syndrome type 1B and Stargardt disease. During her postdoctoral studies at Genethon (France), she advanced AAV-based gene therapy for Pompe disease, improving efficacy through transgene and promoter engineering. Her work has contributed to several ongoing clinical trials, including those for USH1B and Pompe disease.
Her research has led to more than 30 peer-reviewed publications (16 as first author, 7 as co-corresponding) and 6 patents. She has received awards including the Marie Skłodowska-Curie Fellowship, the Innovative Research Grant from the National MPS Society, and Stanford School of Medicine Shoshana Levy Award to Support Women in Science (Career Development Award). She was also a finalist for the ERC Starting Grant in 2019. -
Todd Coleman
Associate Professor of Bioengineering and, by courtesy, of Electrical Engineering
BioTodd P. Coleman is an Associate Professor in the Department of Bioengineering, and by courtesy, Electrical Engineering at Stanford University. He received B.S. degrees in electrical engineering (summa cum laude), as well as computer engineering (summa cum laude) from the University of Michigan (Go Blue). He received M.S. and Ph.D. degrees from MIT in electrical engineering and computer science. He did postdoctoral studies at MIT and Mass General Hospital in quantitative neuroscience. He previously was a faculty member in the Departments of Electrical & Computer Engineering and Bioengineering at the University of Illinois, Urbana-Champaign, and the University of California, San Diego, respectively. Dr. Coleman’s research is very multi-disciplinary, using tools from applied probability, physiology, and bioelectronics. Examples include, for instance, optimal transport methods in high-dimensional uncertainty quantification and developing technologies and algorithms to monitor and modulate physiology of the nervous systems in the brain and visceral organs. He has served as a Principal Investigator on grants from the NSF, NIH, Department of Defense, and multiple private foundations. Dr. Coleman is an inventor on 10 granted US patents. He has been selected as a Gilbreth Lecturer for the National Academy of Engineering, a TEDMED speaker, and a Fellow of IEEE as well as the American Institute for Medical and Biological Engineering. He recently served as Chair of the National Academies Standing Committee on Biotechnology Capabilities and National Security Needs.
