School of Medicine
Showing 1,021-1,030 of 1,431 Results
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Sneha Ramakrishna
Assistant Professor of Pediatrics (Hematology/Oncology)
BioSneha Ramakrishna obtained her B. A. from the University of Chicago and her M.D. from the Cleveland Clinic Lerner College of Medicine at Case Western Reserve University. In medical school, through the Howard Hughes Medical Research Scholar Award, she joined Dr. Crystal Mackall’s laboratory, where she designed and developed various GD2 CAR-Ts and tested them in preclinical models. During her residency training in Pediatrics at the Children’s Hospital of Philadelphia, she cared for some of the first patients treated with CD19 CAR T cells, learning the power of this therapy first-hand. During her fellowship in Pediatric Hematology/Oncology at the Johns Hopkins/National Cancer Institute combined program, she worked with Dr. Terry Fry. She evaluated the mechanism of CD22 CAR T cell relapse in patients by developing an antigen escape model and establishing a deeper understanding of the effects of antigen density on CAR-T phenotype, expansion, and persistence (Fry…Ramakrishna…Mackall Nat Med, 2018; Ramakrishna, et al., Clinical Cancer Research, 2019). Since arriving at Stanford, Dr. Ramakrishna leads an interdisciplinary team that designs, develops, and successfully implements a robust correlative science platform for our novel CAR-T therapies. Analyzing patient samples from our first-in-human GD2 CAR-T trial (NCT04196413) treating a universally fatal cancer, diffuse midline glioma (DMG), we identified that intracerebroventricular CAR-T administration correlates with enhanced pro-inflammatory cytokines and reduced immunosuppressive cell populations in cerebrospinal fluid as compared to intravenous CAR-T administration (Majzner*, Ramakrishna*, et al., Nature 2022 *co-first authors). Her research program evaluates unique sets of patient samples using novel single-cell immune profiling to identify the drivers of CAR-T success or failure. Building on these findings, her team assesses approaches to enhance CAR-T efficacy and translate these findings to the clinic.
Clinically, Dr. Ramakrishna cares for children with solid tumors and treats hematologic, solid, and brain tumor pediatric patients with CAR T cell therapies in the Cancer Cellular Therapies program. -
Mahalakshmi Ramamurthy
Postdoctoral Scholar, Developmental Behavioral Pediatrics
BioI am a postdoctoral scholar working with Dr. Jason Yeatman. With a background in vision science, psychophysics and developmental cognitive neuroscience my long-term goal is to study the intersection of basic visual mechanisms and various neurodevelopmental disorders and to extend this understanding in creating effective early screening tools, and in advancing evidence-based therapeutic and remediation programs. Inherent to this interest is the need for developmental data in large and demographically diverse populations. I strongly believe that such inclusive research not only contributes to scientific advancements but can go beyond to bridge health and education disparities.
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Anoop Rao
Clinical Assistant Professor, Pediatrics - Neonatal and Developmental Medicine
Current Research and Scholarly InterestsWearable senors, unobtrusive vital sign monitoring, natural language processing/text mining
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Lindsey Rasmussen
Clinical Associate Professor, Pediatrics - Critical Care
Clinical Associate Professor (By courtesy), Neurology & Neurological SciencesCurrent Research and Scholarly InterestsMy research interests reside in the field of Neurocritical Care Medicine. My research focus has included inflammation following traumatic brain injury, outcome prediction after cardiac arrest, and neuro-monitoring in the pediatric intensive care setting. These interests are integrated clinically to focus on the merging of specialized neurologic monitoring and care with prognostic efforts in critically ill patients.
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Caroline E. Rassbach
Clinical Professor, Pediatrics
Clinical Professor, Emergency Medicine
Clinical Professor, Emergency MedicineCurrent Research and Scholarly InterestsMedical education including learner assessment, program development and mentoring and coaching in medicine.
