Stanford University
Showing 301-362 of 362 Results
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Michael Snyder, Ph.D.
Stanford W. Ascherman Professor of Genetics
Current Research and Scholarly InterestsOur laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states
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Lars Steinmetz
Dieter Schwarz Foundation Endowed Professor
Current Research and Scholarly InterestsWe apply diverse genomic approaches to understand how genetic variation affects health and disease by: 1) functional and mechanistic analyses of gene regulation, 2) analyses of genetic and environmental interactions, and 3) characterization of diseases in human cells and model organisms. We integrate wet lab and computational genomic approaches, and develop technologies to enable personalized medicine.
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Han Sun
Postdoctoral Scholar, Genetics
Biostatistician 2, Pediatrics - EndocrinologyBioHan had been a postdoc with Dr. Steinmetz at the genetics department for five years, working on both cancers and heart diseases, trying to understand the mechanisms linking from variants to disease phenotypes. This led to a few very interesting findings of aberrant splicing regulation, such as splicing-mediated readthrough stabilization (SRS), one more mechanism for oncogene activation in multiple types of cancers, and tissue-specific splicing of a mitochondrial inner membrane protein, suggesting a molecular connection between deficiency in energy-supplying and dilated cardiomyopathy.
After being a senior computational biologist with Dr. Gloyn, who has been dedicated to the research of type 2 diabetes for decades, Han switched to the field of this multifactorial metabolic disease. It did take some courage to make such a switch at his post-postdoc stage, however, Han has a consistent interest in studying PG&E, which is not pacific gas and electric nearby, but the interaction between phenotype, genotype, and environment. With years of hands-on experience in statistical modeling and the analysis of next-generation sequencing and mass spectrometry data, in addition to a good understanding of disease genetics, cancer biology, and systems biology, Han is highly confident that he will enjoy the adventure and contribute to our understanding of diabetes. -
Hua Tang
Professor of Genetics and, by courtesy, of Statistics
Current Research and Scholarly InterestsDevelop statistical and computational methods for population genomics analyses; modeling human evolutionary history; genetic association studies in admixed populations.
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Abbey Thompson
Director, Educational Outreach, Genetics
Current Role at Stanford1) Directs the Stanford@TheTech program, which trains graduate students and postdoctoral fellows in science communication skills by running hand-on activities at The Tech Interactive in San Jose.
2) Works with The Tech Interactive to design new hands-on experiences for the Biotinkering Lab, as part of an NIH SEPA grant.
3) Runs "Ask a Geneticist" on the Understanding Genetics website, answering genetics questions submitted by people from around the world.
4) Serves as liaison between the Department of Genetics at Stanford University and The Tech. -
Alice Ting
Professor of Genetics, of Biology and, by courtesy, of Chemistry
Current Research and Scholarly InterestsWe develop chemogenetic and optogenetic technologies for probing and manipulating protein networks, cellular RNA, and the function of mitochondria and the mammalian brain. Our technologies draw from protein engineering, directed evolution, chemical biology, organic synthesis, high-resolution microscopy, genetics, and computational design.
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Alexander Eckehart Urban
Associate Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator) and of Genetics
Current Research and Scholarly InterestsComplex behavioral and neuropsychiatric phenotypes often have a strong genetic component. This genetic component is often extremely complex and difficult to dissect. The current revolution in genome technology means that we can avail ourselves to tools that make it possible for the first time to begin understanding the complex genetic and epigenetic interactions at the basis of the human mind.
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Alun Vaughan Jackson
Postdoctoral Scholar, Genetics
BioCollaborative postdoctoral fellow between the groups of Prof. Michael Bassik (Stanford) and Dr Andreas Puschnik (CZ Biohub) interested in host-virus interactions with the innate immune system.
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Anne Villeneuve
Berthold and Belle N. Guggenhime Professor and Professor of Developmental Biology and of Genetics
Current Research and Scholarly InterestsMechanisms underlying homologous chromosome pairing, DNA recombination and chromosome remodeling during meiosis, using the nematode Caenorhabditis elegans as an experimental system. High-resolution 3-D imaging of dynamic reorganization of chromosome architecture. Role of protease inhibitors in regulating sperm activation.
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Elisa Mariel Visher
Postdoctoral Scholar, Genetics
Current Research and Scholarly InterestsElisa Visher is broadly interested in the (co)evolution of life history strategies, niche breadth, diversification, and adaptability. They use mostly experimental evolution methods in microbial systems to test the predictions and assumptions of theoretical literature. Currently, they am especially interested in understanding the genetics of trade-offs in microbes to better understand patterns of diversity in nature and constraints to adaptation.
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Douglas Vollrath
Professor of Genetics and, by courtesy, of Ophthalmology
Current Research and Scholarly InterestsThe Vollrath lab works to uncover molecular mechanisms relevant to the health and pathology of the outer retina. We study metabolic and other cellular interactions between the glial-like retinal pigment epithelium (RPE) and adjacent photoreceptors, with the goals of understanding the pathogenesis of photoreceptor degenerative diseases such as age-related macular degeneration and retinitis pigmentosa, and developing therapies.
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Katarzyna Wac
Affiliate, Genetics
Visiting Scholar, GeneticsBioKatarzyna Wac, Full Professor of Computer Science
Quality of Life Technologies lab, Geneva School of Economics and Management, Center for Informatics, University of Geneva, Switzerland
Research Vision: Leveraging behavioural markers to quantify and improve individuals’ Quality of Life in new ways – drawing on new emerging models from computer science incorporating examination, diagnosis, and treatment of daily life as an “organ” – much like a cardiologist examines heart - and the resulting Quality of Life as a "longitudinal vital sign" - routinely reported for patients and non-patients alike. -
Tao Wang (王韬)
Research Scientist, Genetics
Current Role at StanfordProject Manager & Scientific Co-lead, PsychENCODE Project
Lead, AI & HPC toolkits for Biomedical Sciences
ENCODE and PsychENCODE Project Data Manager
Research Scientist, US Veteran Affairs Hospital -
Shannon White
Postdoctoral Scholar, Genetics
BioHi, I'm Shannon White. I began my postdoctoral fellowship in Michael Snyder's lab in the fall of 2020. I received my PhD from Georgetown University in Tumor Biology in Chunling Yi's lab. My graduate worked explore the signaling and metabolic vulnerabilities of NF2-mutant tumors following YAP/TAZ depletion. My postdoctoral work is exploring the epigenetic hallmarks that contribute to colon cancer progression and drug resistance. I am developing colon organoids derived from pre-cancerous polyp tissue collected from Familial Adenomatous Polyposis patients as a model system to investigate epigenetic and signaling responses to chemoprevention treatments.
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Monte Winslow
Associate Professor of Genetics and of Pathology
Current Research and Scholarly InterestsOur laboratory uses genome-wide methods to uncover alterations that drive cancer progression and metastasis in genetically-engineered mouse models of human cancers. We combine cell-culture based mechanistic studies with our ability to alter pathways of interest during tumor progression in vivo to better understand each step of metastatic spread and to uncover the therapeutic vulnerabilities of advanced cancer cells.
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John Witte
Professor of Epidemiology and Population Health, of Biomedical Data Science and, by courtesy, of Genetics
BioDr. Witte joined the Stanford community in July 2021. In addition to serving as Vice Chair and professor in the Department of Epidemiology & Population Health, and as a professor of Biomedical Data Science and, by courtesy, of Genetics, he will also serve as a member of the Stanford Cancer Institute.
Dr. Witte is an internationally recognized expert in genetic epidemiology. His scholarly contributions include deciphering the genetic and environmental basis of prostate cancer and developing widely used methods for the genetic epidemiologic study of disease. His prostate cancer work has used comprehensive genome-wide studies of germline genetics, transcriptomics, and somatic genomics to successfully detect novel variants underlying the risk and aggressiveness of this common disease. A key aspect of this work has been distinguishing genetic factors that may drive increased prostate cancer risk and mortality among African American men. Providing an avenue to determine which men are more likely to be diagnosed with clinically relevant prostate cancer and require additional screening or specific treatment can help reduce disparities in disease prevalence and outcomes across populations. Dr. Witte has also developed novel hierarchical and polygenic risk score modeling for undertaking genetic epidemiology studies. These advances significantly improve our ability to detect disease-causing genes and to translate genetic epidemiologic findings into medical practice.
Dr. Witte has received the Leadership Award from the International Genetic Epidemiology Society (highest award), and the Stephen B. Hulley Award for Excellence in Teaching. His extensive teaching portfolio includes a series of courses in genetic and molecular epidemiology. He has mentored over 50 graduate students and postdoctoral fellows, serves on the executive committees of multiple graduate programs, and has directed a National Institutes of Health funded post-doctoral training program in genetic epidemiology for over 20 years. Recently appointed to the National Cancer Institute Board of Scientific Counselors, Dr. Witte has been continuously supported by the National Institutes of Health. -
Yue Wu
Postdoctoral Scholar, Genetics
Current Research and Scholarly InterestsI built computational methods to integrate and model biological time series, including metabolic dynamics, longitudinal multi-omics data, and micro-sampling. I reduce dimensions, built clusters, and search for causal links.
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Lei Xiong
Postdoctoral Scholar, Genetics
Current Research and Scholarly InterestsMy research focuses on develop deep learning methods to
1. Infer macrophage-tumor cells interaction using spatial multi-omics
2. Decipher the cis-regulatory code using a large language models
3. Predict enhancer-promoter interaction
4. Multi-omics integration
5. Build foundational model for single-cell genomics
