Stanford University
Showing 201-220 of 241 Results
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Jennifer Tremmel
Susan P. and Riley P. Bechtel Medical Director and Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsDr. Tremmel studies sex differences in cardiovascular disease. Current research projects include evaluating sex differences in coronary pathophysiology, young patients presenting with myocardial infarction, the impact of stress on anginal symptoms, chronic total coronary occlusions, and vascular access site complications.
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Philip S. Tsao, PhD
Professor (Research) of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsOur primary interests are in the molecular underpinnings of vascular disease as well as assessing disease risk. In addition to targeted investigation of specific signaling molecules, we utilize global genomic analysis to identify gene expression networks and regulatory units. We are particularly interested in the role of microRNAs in gene expression pathways associated with disease.
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Jason V. Tso, MD
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
BioDr. Tso is a board-certified cardiologist with the Sports Cardiology Program and the Center for Inherited Cardiovascular Disease. He serves as medical director of the Sports Cardiology Program and is a clinical assistant professor in the Division of Cardiovascular Medicine at Stanford University School of Medicine.
With clinical expertise in sports cardiology, Dr. Tso specializes in treating physically active patients. He cares for recreational weekend warriors, elite and professional athletes, and all those in between.
He has experience caring for athletes from professional sports teams and multiple National Collegiate Athletic Association (NCAA) Division I universities. Dr. Tso performs cardiac screening and consultation for multiple Bay Area sports teams and is the team cardiologist for Stanford Athletics and the San Francisco 49ers.
Dr. Tso’s research interests include cardiovascular health and adaptation in athletes. He has spent years studying American-style football players and Masters endurance athletes. He has presented his research at multiple national meetings, including the American College of Cardiology Scientific Sessions, American Heart Association Scientific Sessions, Heart Failure Society of America, and American College of Sports Medicine.
Dr. Tso’s research has been published in multiple peer-reviewed journals including the Journal of the American Heart Association, the European Journal of Preventive Cardiology, and the British Journal of Sports Medicine. He also regularly serves as a reviewer for multiple cardiology and sports medicine journals. -
Mirela Tuzovic, MD
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
BioDr. Mirela Tuzovic is a board-certified, fellowship-trained cardiologist and medical director of the Stanford Health Care Center for Marfan Syndrome and Related Aortic Disorders. Dr. Tuzovic is also a clinical assistant professor in the Department of Medicine, Division of Cardiovascular Medicine at Stanford University School of Medicine.
Dr. Tuzovic diagnoses and treats a wide range of cardiovascular conditions, including aortic disorders, Marfan syndrome and other heritable thoracic aortic disorders, and cardiovascular disease. She also specializes in cardiovascular imaging and structural echocardiology. For each of her patients, she offers a comprehensive, personalized care plan.
Dr. Tuzovic’s research interests include the diagnosis and management of patients with aortic disease as well as cardiovascular imaging. As a structural echocardiographer, she is involved in multiple clinical trials for transcatheter valve repair and replacement through the Stanford Health Care Structural Heart Program. Her prior research focus has included echocardiography and cardio-oncology.
Dr. Tuzovic has published her research in peer-reviewed journals such as Circulation, the American Journal of Cardiology, Echocardiography, and JACC: CardioOncology.
Dr. Tuzovic is a member of the American College of Cardiology, the American Society of Echocardiography, and the Montalcino Aortic Consortium. -
Randall Vagelos, MD
Professor of Medicine (Cardiovascular)
Current Research and Scholarly InterestsI. Congestive Heart Failure New Medical Therapies Prognostic Evaluation Selection for Cardiac Transplantation II. Screening for Myocardial Necrosis New ECG Monitoring Devices New Serum Markers III. Screening for CAD Patients Who Have Received Radiation Rx Diabetics Being Considered for Renal Transplantation
IV. Advanced coronary and valvular disease, evaluationg candidacy for high risk interventions. -
Hannah Valantine
Professor of Medicine (Cardiovascular)
Current Research and Scholarly InterestsMy lab is focused on understanding the mechanism mediating acute and chronic allograft failure, in particular on the role of microvascular injury in acute allograft failure and the mechanisms of mediating transplant coronary artery disease. 1. Role of microvascular injury in acute allograft failure.
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Laurens van de Wiel
Postdoctoral Scholar, Cardiovascular Medicine
BioI am a post-doctoral researcher at Stanford University under supervision of Matthew Wheeler and Stephen Montgomery. My research focuses on understanding the entire spectrum of genetic variation effects on protein function and structure in order to decipher molecular mechanisms of disease.
My post-doctoral work centers on developing novel software methodologies which combine multi-omics data to interpret the functional impact of genetic variants in undiagnosed patients. I am part of the Undiagnosed Disease Network (UDN) at Stanford Center for Undiagnosed Diseases (CUD), Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) consortium at GREGoR Stanford Site (GSS), and the Molecular Transducers of Physical Activity Consortium (MoTrPAC) at the Bioinformatics Center (BIC).
Before joining Stanford. I was received my Ph.D. in 2021 at the Radboud University Medical Center under supervision of Christian Gilissen, Gert Vriend, and Joris Veltman. I received my MSc degree in 2014 at Radboud University under supervision of Tom Heskes, Evgeni Levin, and Armand Paauw. Before my Ph.D, I worked as a Data Scientist at FLXone, where I developed machine learning solutions within a large-scale, real-time infrastructure.
Research
I am interested in a variety of topics in Bioinformatics and Computer Science. In particular, I am interested in the application of Artificial Intelligence and Statistical Modelling to analyse human (Rare) Mendelian Disease Genetics, Evolutionary Comparative Genomics, Protein Domain Homology, and Molecular Structures. -
Anubodh Sunny Varshney
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
BioDr. Anubodh Sunny Varshney is a Clinical Assistant Professor, Medical Director of Mechanical Circulatory Support, and Associate Director of the Fellowship Program in the Section of Advanced Heart Failure, Transplant Cardiology, and Mechanical Circulatory Support at Stanford. In addition to caring for patients with advanced heart disease, he is also a clinical researcher and works to identify patient groups that have sub-optimal outcomes with current therapies, define benchmark outcomes that next generation therapies should improve upon, and understand factors that influence adoption of novel drug and device therapies for cardiovascular disease.
Dr. Varshney earned a BS in biomedical engineering from Washington University in St. Louis and an MD from the University of Texas Southwestern Medical School. He completed residency in Internal Medicine and fellowship in Cardiovascular Medicine at Brigham & Women’s Hospital/Harvard Medical School and fellowship in Advanced Heart Failure, Transplant Cardiology, and Mechanical Circulatory Support at Stanford University.
Dr. Varshney also has experience advising multiple medical device, drug, and digital health start-ups and currently serves as a Venture Advisor at Broadview Ventures, a philanthropically-funded, mission-driven investment organization that invests in early-stage companies developing technologies that have the potential to improve outcomes for patients with cardiovascular disease or stroke. -
Paul J. Wang, MD
John R. and Ai Giak L. Singleton Director, Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Bioengineering
Current Research and Scholarly InterestsDr. Wang's research centers on the development of innovative approaches to the treatment of arrhythmias, including more effective catheter ablation techniques, more reliable implantable devices, and less invasive treatments. Dr. Wang's clinical research interests include atrial fibrillation, ventricular tachycardia, syncope, and hypertrophic cardiomyopathy. Dr. Wang is committed to addressing disparities in care and is actively involved in increasing diversity in clinical trials.
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Chad S. Weldy, M.D., Ph.D.
Instructor, Medicine - Cardiovascular Medicine
Current Research and Scholarly InterestsAs a physician-scientist I work to understand the genetic basis of cardiovascular disease and the transcriptional and epigenomic mechanisms of atherosclerosis. My work is focused across four main areas of cardiovascular genetics and mechanisms of coronary artery disease and smooth muscle biology:
1.Vascular smooth muscle specific ADAR1 mediated RNA editing of double stranded RNA and activation of the double stranded RNA receptor MDA5 in coronary artery disease and vascular calcification
2.Defining on single cell resolution the cellular and epigenomic features of human vascular disease across vascular beds of differing embryonic origin
3.CRISPRi screening with targeted perturb seq (TAPseq) to identify novel CAD genes in human coronary artery smooth muscle cells
4.Investigation of the epigenetic and molecular basis of coronary artery disease and smooth muscle cell transition in mice with conditional smooth muscle genetic deletion of CAD genes Pdgfd and Sox9
My work is focused on discovery of causal mechanisms of disease through leveraging human genetics with sophisticated molecular biology, single cell sequencing technologies, and mouse models of disease. This work attempts to apply multiple scientific research arms to ultimately lead to novel understandings of vascular disease and discover important new therapeutic approaches for drug discovery.
First Author Manuscripts for this work:
•Weldy, C. S., et al. (2025). Smooth muscle cell expression of RNA editing enzyme ADAR1 controls activation of RNA sensor MDA5 in atherosclerosis. (2025). Nature Cardiovascular Research. 1-17, PMID: 40958051, doi: 10.1038/s44161-025-00710-5
•*Selected as finalist for Louis N. and Arnold M. Katz Basic Science Research Prize from the American Heart Association, finalist competition November 16, 2024, Chicago
•Work was highlighted in the Stanford Department of Medicine News
https://medicine.stanford.edu/news/current-news/standard-news/RNA-editing.html
•Weldy, C.S., et al. (2025). Epigenomic landscape of single vascular cells reflects developmental origin and disease risk loci. Molecular Systems Biology. 1-25, PMID: 40931195, doi:10.1038/s44320-025-00140-2.
•*Selected for the cover of November 2025 edition of Molecular Systems Biology
Grant funding received for this work:
Mentored Clinical Scientist Research Career Development Award (K08)(NIH/NHLBI, 1 K08 HL167699-01), August, 2023 – July 2028. PI: Weldy, Chad
•Title of proposal: “ADAR Mediated RNA editing is a causal mechanism in coronary artery disease”.
•Activated 08/01/2023
•$850,000 over 5 years
Career Development Award, American Heart Association (AHA CDA)(23CDA1042900), July, 2023 – June, 2026. PI: Weldy, Chad
•Title of proposal: “Linking RNA editing to coronary artery calcification and disease”
•Activated 07/01/2023
•$231,000 over three years
NIH Loan Repayment Program (LRP) Award (NIH/NHLBI) Renewal Award, July, 2023. PI: Weldy, Chad
•Title of proposal: “RNA editing is a causal mechanism of coronary artery disease”
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32) (NIH/NHLBI, 1 F32 HL160067-01), July, 2021 – June 2023 (Completed). PI: Weldy, Chad
• Titled, “A transcriptional network which governs smooth muscle transition is mediated by causal coronary artery disease gene PDGFD”
•*Received perfect score with impact score 10, 1st percentile
NIH Loan Repayment Program (LRP) Award (NIH/NHLBI), July, 2021. PI: Weldy, Chad
•Title of proposal: "Single cell transcriptomic and epigenomic features of human atherosclerosis".
•This will award up to $100,000 towards student loans over the next 24 months with opportunity for renewal after 24 months. -
Matthew T. Wheeler
Associate Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsTranslational research in rare and undiagnosed diseases. Basic and clinical research in cardiomyopathy genetics, mechanisms, screening, and treatment. Investigating novel agents for treatment of hypertrophic cardiomyopathy and new mechanisms in heart failure. Cardiovascular screening and genetics in competitive athletes, disease gene discovery in cardiomyopathy and rare disease. Informatics approaches to rare disease and multiomics. Molecular transducers of physical activity bioinformatics.
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Ronald Witteles
Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly Interests1) Amyloidosis -- Optimizing diagnosis/therapy and discovering new treatments
2) CardioOncology -- Understanding, treating, and preventing cancer therapy-induced cardiotoxicity
3) Sarcoidosis -- Exploring novel diagnostic modalities and determining optimal treatment, with a focus on cardiac sarcoidosis -
Jennifer Woo, MD
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
Clinical Assistant Professor, Pediatrics - CardiologyBioDr. Woo is a board-certified, fellowship-trained cardiologist with the Adult Congenital Heart Program at Stanford Health Care. She is also a clinical assistant professor in the Divisions of Cardiovascular Medicine and Pediatric Cardiology at Stanford University School of Medicine.
She diagnoses and treats a range of cardiovascular diseases, with a focus on adult congenital heart disease. Dr. Woo has Level III training with the National Board of Echocardiography, a certification that recognizes her experience in complex cardiac imaging. She also has specialized expertise in cardiac MRI. Each of her patients receives a personalized, comprehensive care plan delivered with compassion.
Dr. Woo is heavily involved in adult congenital heart disease research. She has a particular interest in imaging and heart failure in adults with congenital heart disease. She has received grant funding for her work, including from the Adult Congenital Heart Association. The National Institutes of Health awarded granted her the Ruth L. Kirschstein National Research Service Award.
She has published research in several peer-reviewed journals, such as the Journal of the American College of Cardiology and Pediatric Cardiology. Dr. Woo has presented her findings at regional and national meetings, including the Adult Congenital Heart Disease Bay Area Conference and the International Symposium on Adult Congenital Heart Disease.
Dr. Woo is a member of the Adult Congenital Heart Association, American College of Cardiology, American Heart Association, and American Society of Echocardiography.
