Stanford University
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Isaac Longobardi
MD Student with Scholarly Concentration in Clinical Research, expected graduation Spring 2030
BioIsaac Longobardi, from Brooklyn, New York, is pursuing an MD at Stanford School of Medicine. He received his bachelor’s degree in social anthropology from Harvard College. Isaac aspires to transform long-term care services and delivery models for individuals with frailty, chronic illness, and mental and behavioral health conditions and their communities. Between 2022 and 2025, Isaac helped to launch and directed the Moving Forward Nursing Home Quality Coalition—a representative group of nursing home stakeholders working to advance recommendations from “The National Imperative to Improve Nursing Home Quality,” a landmark 2022 report by the National Academies of Sciences, Engineering, and Medicine. Prior to that, he piloted multigenerational living while working as a volunteer youth and community engagement program coordinator at Hebrew SeniorLife, a Boston-based elder services nonprofit. Isaac’s speaking and writing on aging and long-term care include award-winning undergraduate research, a Substack, co-authored health policy articles, and conference presentations.
ORCID: https://orcid.org/0009-0009-8481-571X -
James Longoria, MD
Clinical Associate Professor, Cardiothoracic Surgery
BioDr. Longoria is a board-certified, fellowship-trained cardiothoracic surgeon. He is a clinical associate professor in the Department of Cardiothoracic Surgery at Stanford University School of Medicine.
Deeply accomplished in all facets of complex adult cardiothoracic procedures, Dr. Longoria is a high-volume surgeon with more than 20 years of experience and an exceptionally low mortality and complication rate.
Dr. Longoria’s surgical experience includes complex mitral valve and tricuspid valve repair, coronary artery bypass grafting, adult congenital repair, as well as procedures for high risk VAD patients. He performs cardiac transplantation, carotid endarterectomy, and implantation of all FDA-approved mechanical circulatory support devices. Additionally, he performs catheter-based valvular procedures (such as transcatheter aortic valve replacement, or TAVR) and open and video-assisted thoracoscopic surgery (VATS) for pulmonary surgical procedures.
He has an applied interest in atrial fibrillation (AFib) and is a nationally recognized expert in the minimally invasive surgical treatment of Atrial Fibrillation (AFib). Dr. Longoria was issued a method patent from the U.S. Patent and Trademark Office for developing the TTMaze (Totally Thoracoscopic) procedure that is central to the Dual Epicardial Endocardial Persistent (DEEP) AFib clinical trial.
Before joining Stanford, Dr. Longoria was the surgical director of cardiac ablation at a prominent AFib center certified by the Society of Chest Pain Centers. He holds patents for a synthetic chord used to connect tissue and for specialized methods he developed to treat cardiac arrhythmias.
At Stanford, Dr. Longoria brings a commitment to patientcentric, personalized care. He is committed to making the experience of surgery as pleasant as possible for his patients. He is also excited for the opportunity to conduct translational research that utilizes the most advanced technology available, in collaboration with colleagues from other disciplines.
For his outcomes and high patient satisfaction ratings, Dr. Longoria has earned awards and recognition, including being named a Top Doctor of Sacramento by his peers for the last five years in a row. He has also been an honoree of the President’s Award for patient satisfaction by the Sutter Independent Physicians.
Dr. Longoria has published articles on genetic variants associated with atrial fibrillation, thoracoscopic left atrial appendage clipping, radiofrequency ablation, and other topics. His work has appeared in the Journal of Thoracic and Cardiovascular Surgery, Annals of Thoracic Surgery, Journal of the American College of Cardiology, Journal of Cardiovascular Electrophysiology, and elsewhere.
He has made numerous presentations on atrial fibrillation surgery and other topics at conferences including the Annual Meeting of the American Association of Thoracic Surgery, Society of Thoracic Surgeons, and International Society for Heart and Lung Transplantation.
Dr. Longoria is a Fellow of the American College of Surgeons and American College of Cardiology. He is a member of the Society of Thoracic Surgeons, Western Thoracic Surgical Association, the International Society for Minimally Invasive Cardiothoracic Surgery, and the Heart Rhythm Society. -
Billy W Loo Jr, MD PhD FASTRO FACR
Professor of Radiation Oncology (Radiation Therapy)
Current Research and Scholarly InterestsMy clinical specialty is precision targeted radiotherapy of thoracic cancers.
My research is on developing next-generation ultra-rapid radiotherapy technology (PHASER) and studying the radiobiological effects of FLASH treatment.
My clinical research is on advanced 4-D image-guided radiotherapy and stereotactic ablative radiotherapy (SABR), and functional and metabolic imaging and imaging biomarkers. -
Jaime Lopez, MD
Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy clinical interests are in the areas of Intraoperative Neurophysiologic Monitoring (IOM), clinical neurophysiology, electromyopgraphy and in the use of botulinum toxins in the treatment of neurologic disorders. Our IOM groups research is in the development of new and innovative techniques for monitoring the nervous system during surgical and endovascular procedures and how these alter surgical management and patient outcomes. I am also active in formulating national IOM practice guidelines.
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Romain Lopez
Affiliate, Genetics
BioSince Fall 2021, I am a joint postdoctoral scholar at Stanford University and Genentech Research and Early Development, hosted by Jonathan Pritchard and Aviv Regev. I recently obtained my PhD degree from the department of Electrical Engineering and Computer Sciences at UC Berkeley, advised by Mike Jordan & Nir Yosef. My research interests lie at the intersection of statistics, computation and modeling with a focus on biological applications.
A significant part of my research is driven by building more statistically accurate and faster machine learning software for analyzing single-cell omics data. I developed single-cell Variational Inference (scVI), a flexible model and a scalable inference method for comprehensive analysis of single-cell transcriptomes. I co-developed scvi-tools, an open-source software suite for fully-probabilistic modeling of single-cell multi-omics data. You may learn more about these topics in my guest lecture of the Deep Learning in the Life Sciences class at MIT.
More generally, I am interested in the broader area of ML + Science. Deep generative models provide an appealing and flexible paradigm for learning distributions, but quite some work is needed to fully exploit them as part of a scientific hypothesis testing pipeline (e.g., causality, interpretability, disentanglement, decision-making).
Previously, I worked on counterfactual inference and offline policy learning methods in collaboration with technology companies. In 2018, I visited Le Song at Ant Financial in Hangzhou. In 2019, I visited Inderjit Dhillon at Amazon in Berkeley. Before graduate school, I obtained a MSc in applied mathematics from Ecole polytechnique, Palaiseau in 2016. Additionally, I worked as an intern at the Harvard Medical School with Allon Klein in 2016. I was born and grew up in Bedarieux, France.
