Wu Tsai Neurosciences Institute


Showing 251-300 of 645 Results

  • Lambertus Hesselink

    Lambertus Hesselink

    Professor of Electrical Engineering and, by courtesy of Applied Physics

    BioHesselink's research encompasses nano-photonics, ultra high density optical data storage, nonlinear optics, optical super-resolution, materials science, three-dimensional image processing and graphics, and Internet technologies.

  • Shaul Hestrin, PhD

    Shaul Hestrin, PhD

    Professor of Comparative Medicine

    Current Research and Scholarly InterestsThe main interest of my lab is to understand how the properties of neocortical neurons, the circuits they form and the inputs they receive give rise to neuronal activity and behavior. Our approach includes behavioral studies, two-photon calcium imaging, in vivo whole cell recording in behaving animals and optogenetic methods to activate or to silence the activity of cortical neurons.

  • Karen G. Hirsch, MD

    Karen G. Hirsch, MD

    Professor of Neurology and Neurological Sciences (Adult Neurology)

    Current Research and Scholarly InterestsDr. Karen G. Hirsch cares for critically ill patients with neurologic disorders in the intensive care unit. Dr. Hirsch's research focuses on using continuous and discrete multi-modal data to develop phenotypes and identify signatures of treatment responsiveness in patients with coma after cardiac arrest. She is the Co-PI of PRECICECAP (PRecision Care In Cardiac ArrEst - ICECAP, NINDS R01 NS119825-01). The research team works closely with collaborators in data science at Stanford and with industry partners to apply machine learning analyses to complex multi-modal ICU data. Dr. Hirsch also studies neuro-imaging in post-cardiac arrest coma and traumatic brain injury, and with colleagues in Cardiac Anesthesia and Cardiothoracic Surgery, Dr. Hirsch studies neurologic outcomes in patients on mechanical circulatory support including ECMO.

    Along with colleagues in Biomedical Ethics, Dr. Hirsch studies brain death, organ donation, and neuroethics. She is the Co-PI of BCI-DEF (Brain Computer Interfaces and Disability: Developing an Inclusive Ethical Framework, NIMH 1R01MH130518-01) which is a BRAIN Initiative funded study that is qualitatively evaluating end user perspectives about the benefits, risks, and ethical challenges of Brain Computer Interfaces for patients with acute stroke or traumatic brain injury.

    Dr. Hirsch is broadly interested in improving neurologic outcomes after acute severe brain injury, identifying early phenotypes to guide precision medicine in neurocritical care, and exploring ethical issues in neurocritical care and novel neurotechnology. Dr. Hirsch greatly appreciates the importance of team science and collaboration.

  • Susan Holmes

    Susan Holmes

    Professor of Statistics, Emerita

    Current Research and Scholarly InterestsOur lab has been developing tools for the analyses of complex data structures, extending work on multivariate data to structured multitable table that include graphs, networks and trees as well as categorical and continuous measurements.
    We created and support the Bioconductor package phyloseq for the analyses of microbial ecology data from the microbiome. We have specialized in developing interactive graphical visualization tools for doing reproducible research in biology.

  • David S. Hong

    David S. Hong

    Associate Professor of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)

    Current Research and Scholarly InterestsDr. Hong is a child and adolescent psychiatrist and clinician-scientist. His responsibilities span clinical care, teaching/mentorship, and research, with a unifying theme of advancing a developmental cognitive framework as applied to psychiatric conditions. Using this core premise, he work encompasses multiple domains: specialized clinical care, fellowship training, research mentorship, and elaborating the role of sex-specific determinants of development, one of the greatest contributors to individual developmental variation.

    His lab investigates genetic and hormonal influences underlying sex differences in child psychiatric conditions. Sex has emerged as a critical variable driving differences in the phenomenology, course, and treatment of many mental health disorders. Unfortunately, an understanding of the biological mechanisms driving these effects are limited. By applying innovative neuroimaging and multiomic approaches, Dr. Hong seeks to provide a deeper understanding of the connection between sex-specific effects and complex psychiatric diseases. To do so, research in the Hong Lab focuses on the role of genes on the X and Y chromosomes, as well as circulating sex hormones on brain development, cognition, and behavior. The lab broadly aims to elucidate the changing nature of these mechanisms across various stages of development.

    Another area of focus is the implementation of clinical informatics in child psychiatry and the development of digital mental health tools. As co-Director of the Mental Health Technology and Innovation Hub, Dr. Hong is helping to develop clinical and research infrastructure within the Department of Psychiatry and Behavioral Sciences to advance development of mobile mental health resources that will improve efficacy and access to mental health care.

  • Guosong Hong

    Guosong Hong

    Assistant Professor of Materials Science and Engineering

    Current Research and Scholarly InterestsGuosong Hong is a materials scientist developing materials-enabled photonic technologies for noninvasive imaging and neuromodulation in living systems. His research pioneers in vivo optical transparency and deep-tissue light-matter interactions, guided by fundamental principles in physics and chemistry, to enable new ways to visualize, modulate, and ultimately treat biological function in health and disease.

  • Yusuke Hori, MD

    Yusuke Hori, MD

    Clinical Instructor, Neurosurgery

    BioDr. Hori received his MD from Sapporo Medical University, Japan, and during that time he served as a Medical Student Research Fellow in the Department of Pharmacology. He explored the functional role of the SIRT1 gene, a longevity-associated gene, and its association with various conditions such as muscular dystrophy. He also completed a Visiting Student Research Fellowship at the Health Sciences University of Hokkaido and participated in Human Genetics projects focusing on an association between the 27-bp deletion and 538G>A mutation in the ABCC11 Gene.

    After graduating from medical school, Dr. Hori completed a neurosurgery residency at National Hospital Organization Okayama Medical Center in Japan. Subsequently, he completed a Stereotactic and Functional Neurosurgery Fellowship and then a Neurosurgical Oncology and Radiosurgery Fellowship at The Cleveland Clinic. He also completed an International Neurosurgery Fellowship at Boston Children's Hospital, Harvard Medical School. In 2022, he moved to Stanford University as a postdoctoral fellow, and under the supervision of Dr. Anca Pasca, he participated in brain organoid research focusing on hypoxic brain injuries.

    Since July 2023, Dr. Hori has been working as a Clinical Instructor (Neurosurgical Oncology and Radiosurgery) in the Department of Neurosurgery at Stanford under the supervision of Dr. Steven D. Chang. His clinical interests include malignant brain and spine tumors in both adult and pediatric patients. His clinical research focuses on the application of minimally invasive treatments such as laser interstitial thermal therapy, focused ultrasound, and radiosurgery to treat various neurosurgical conditions. His current lab research aims to develop an organoid model for radiation-induced brain injuries and a high-throughput screening platform to identify novel therapeutic compounds, for which he received a Clinician Educator Grant from Stanford University Maternal and Child Health Research Institute. Outside of medicine, he enjoys playing music including guitar and drums.

  • Mark Horowitz

    Mark Horowitz

    Fortinet Founders Chair of the Department of Electrical Engineering, Yahoo! Founders Professor in the School of Engineering and Professor of Computer Science

    BioProfessor Horowitz initially focused on designing high-performance digital systems by combining work in computer-aided design tools, circuit design, and system architecture. During this time, he built a number of early RISC microprocessors, and contributed to the design of early distributed shared memory multiprocessors. In 1990, Dr. Horowitz took leave from Stanford to help start Rambus Inc., a company designing high-bandwidth memory interface technology. After returning in 1991, his research group pioneered many innovations in high-speed link design, and many of today’s high speed link designs are designed by his former students or colleagues from Rambus.

    In the 2000s he started a long collaboration with Prof. Levoy on computational photography, which included work that led to the Lytro camera, whose photographs could be refocused after they were captured.. Dr. Horowitz's current research interests are quite broad and span using EE and CS analysis methods to problems in neuro and molecular biology to creating new agile design methodologies for analog and digital VLSI circuits. He remains interested in learning new things, and building interdisciplinary teams.

  • Hadi Hosseini

    Hadi Hosseini

    Associate Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)

    Current Research and Scholarly InterestsOur lab’s research portfolio crosses multiple disciplines including computational neuropsychiatry, cognitive neuroscience, multimodal neuroimaging and neurocognitive rehabilitation. Our computational neuropsychiatry research mainly involves investigating alterations in the organization of connectome in various neurodevelopmental and neurocognitive disorders using state of the art neuroimaging techniques (fMRI, sMRI, DWI, functional NIRS) combined with novel computational methods (graph theoretical and multivariate pattern analyses).

    The ultimate goal of our research is to translate the findings from computational neuropsychiatry research toward developing personalized interventions. We have been developing personalized interventions that integrate computerized cognitive rehabilitation, real-time functional brain imaging and neurofeedback, as well as virtual reality (VR) tailored toward targeted rehabilitation of the affected brain networks in patients with neurocognitive disorders.

  • Roger Howe

    Roger Howe

    William E. Ayer Professor of Electrical Engineering, Emeritus

    BioDesign and fabrication of sensors and actuators using micro and nanotechnologies, with applications to information processing and energy conversion.

  • Yang Hu, MD, PhD

    Yang Hu, MD, PhD

    Professor of Ophthalmology
    On Partial Leave from 01/05/2026 To 07/31/2026

    Current Research and Scholarly InterestsThe ultimate goal of the laboratory is to develop efficient therapeutic strategies to achieve CNS neural repair, through promoting neuroprotection, axon regeneration and functional recovery.

    More specifically, we study retinal ganglion cell (RGC) and optic nerve in various optic neuropathies including traumatic, glaucomatous and inflammatory optic nerve injuries to fully understand the molecular mechanisms of CNS neurodegeneration and axon regeneration failure.

  • Ting-Ting Huang

    Ting-Ting Huang

    Associate Professor (Research) of Neurology (Adult Neurology), Emerita

    Current Research and Scholarly InterestsWe study the role of oxygen free radicals in oxidative tissue damage and degeneration. Our research tools include transgenic and knockout mice and tissue culture cells for in vitro gene expression.

  • Andrew D. Huberman

    Andrew D. Huberman

    Associate Professor of Neurobiology and, by courtesy, of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsAndrew Huberman is a tenured associate professor of neurobiology and of ophthalmology at Stanford University School of Medicine, where he directs the Huberman Lab. After earning his B.A. from the University of California, Santa Barbara and completing M.A. and Ph.D. degrees in neuroscience at UC Berkeley and UC Davis, he conducted post-doctoral work at Stanford.

  • John Huguenard

    John Huguenard

    Professor of Neurology and Neurological Sciences (Neurology Research), of Neurosurgery (Adult Neurosurgery) and, by courtesy, of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsWe are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.

  • Keith Humphreys

    Keith Humphreys

    Esther Ting Memorial Professor and Professor, by courtesy, of Health Policy

    Current Research and Scholarly InterestsDr. Humphreys researches individual and societal level interventions for addictive and psychiatric disorders. He focuses particularly on evaluating the outcomes of professionally-administered treatments and peer-operated self-help groups (e.g., Alcoholics Anonymous), and, analyzing the impact of public policies touching addiction, mental health, public health, and public safety.

  • Ruth Huttenhain

    Ruth Huttenhain

    Assistant Professor of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsMy group deciphers how G protein-coupled receptors decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses. We exploit quantitative proteomics to capture the spatiotemporal organization of signaling networks combined with functional genomics to study their impact on physiology.

  • Md Tauhidul Islam

    Md Tauhidul Islam

    Assistant Professor of Radiation Oncology (Radiation Physics)

    Current Research and Scholarly InterestsMy research focuses on developing computationally efficient and clinically reliable AI methods for biomedical imaging and high-dimensional molecular data, with an emphasis on cancer and neurological disease. The Islam Lab designs novel representations and learning frameworks that improve deep learning performance in data-constrained biomedical settings, including methods that transform tabular omics data into spatially meaningful representations.

  • Robert K. Jackler, MD

    Robert K. Jackler, MD

    Edward C. and Amy H. Sewall Professor, Emeritus

    Current Research and Scholarly InterestsSince the early 2000s, study of tobacco industry marketing has become my primary field of research. Motivated by the lack of a comprehensive and well-organized compendium of tobacco advertisements, and the relative paucity of scholarly research analyzing the marketing practices of the industry, I chose to focus my research on advertising. The overarching purpose of my research has been to reveal the behavior of the tobacco industry in recruiting and retaining its consumers with the goal of infor

  • Peter K.  Jackson

    Peter K.  Jackson

    Professor of Microbiology and Immunology (Baxter Labs) and of Pathology

    Current Research and Scholarly InterestsCell cycle and cyclin control of DNA replication .

  • Abhi Jain

    Abhi Jain

    Clinical Assistant Professor, Radiology

    BioDr. Jain is a neuroradiologist and a Certified Imaging Informatics Professional (CIIP) whose academic work bridges day-to-day neuroradiology practice with imaging informatics and clinically grounded artificial intelligence (AI).

    His clinical research interests include quantitative imaging and radiomics in cerebrovascular disease, with particular emphasis on intracerebral hemorrhage (ICH), and imaging biomarkers in the aging brain and neurodegeneration, including limbic-predominant age-related TDP-43 encephalopathy (LATE).

    His AI/informatics and quality-improvement interests include large language models (LLMs) for radiology reporting support and clinical decision support, with an emphasis on real-world evaluation and workflow integration.

    His education interests focus on modern, technology-enabled neuroradiology teaching, including tailored language models and extended reality (XR; augmented/virtual/mixed reality) approaches to strengthen trainee learning.

  • Siddhartha Jaiswal

    Siddhartha Jaiswal

    Associate Professor of Pathology

    Current Research and Scholarly InterestsWe identified a common disorder of aging called clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs due to certain somatic mutations in blood stem cells and represents a precursor state for blood cancer, but is also associated with increased risk of cardiovascular disease and death. We hope to understand more about the biology and clinical implications of CHIP using human and model system studies.

  • Daniel Jarosz

    Daniel Jarosz

    Senior Associate Dean, Basic Science, Professor of Chemical and Systems Biology and of Developmental Biology

    Current Research and Scholarly InterestsMy laboratory studies conformational switches in evolution, disease, and development. We focus on how molecular chaperones, proteins that help other biomolecules to fold, affect the phenotypic output of genetic variation. To do so we combine classical biochemistry and genetics with systems-level approaches. Ultimately we seek to understand how homeostatic mechanisms influence the acquisition of biological novelty and identify means of manipulating them for therapeutic and biosynthetic benefit.

  • Booil Jo

    Booil Jo

    Professor of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)

    Current Research and Scholarly InterestsLatent Variable Modeling, Causal Inference, Longitudinal Data Analysis, Missing Data Analysis, Mixture and Growth Mixture Modeling, Prevention Science Methodology.

  • Julia Kaltschmidt

    Julia Kaltschmidt

    Professor of Neurosurgery

    Current Research and Scholarly InterestsThe lab’s primary research interest is to understand how specific neuronal circuits are established. We use mouse genetics, combinatorial immunochemical labeling and high-resolution laser scanning microscopy to identify, manipulate, and quantitatively analyze synaptic contacts within the complex neuronal milieu of the spinal cord and the enteric nervous system.

  • Tahereh Kamali

    Tahereh Kamali

    Instructor, Adult Neurology

    Current Research and Scholarly InterestsAI for Healthcare, Neuroimaging, Biomarkers Development

  • Spyros Karadimas, MD, PhD

    Spyros Karadimas, MD, PhD

    Assistant Professor of Neurosurgery

    BioDr. Spyridon Karadimas is a board-certified, fellowship-trained cerebrovascular neurosurgeon and physician-scientist with Stanford Health Care. He is also an assistant professor in the Department of Neurosurgery at Stanford University School of Medicine.

    Dr. Karadimas offers advanced, personalized treatment for complex vascular disorders of the brain, neck, and spine in both adults and children. His expertise spans brain aneurysms, arteriovenous malformations, cavernous malformations, arteriovenous fistulas, Moyamoya disease, stroke, and carotid artery disease. Dr. Karadimas is a rare combination of surgeon, scientist, and innovator dedicated to advancing patient care and shaping the future of cerebrovascular neurosurgery.

    Dr. Karadimas directs a basic and translational research program focused on the neural circuits of motor control and stroke recovery. His laboratory integrates systems neuroscience, in vivo imaging, electrophysiology, and brain-computer interface development to uncover the principles of neuroplasticity, or how the brain adapts to change. This knowledge allows him to create new ways to help people move again after a brain injury.

    Dr. Karadimas has published his research as first author in peer-reviewed journals such as Nature, Nature Neuroscience and Science Translational Medicine. His work has received editorial highlight at Nature Reviews Neuroscience. He has presented to his peers at international, national, and regional meetings, including those of the American Academy of Neurological Surgery, American Association of Neurological Surgeons (AANS), European Association of Neurosurgical Societies, and World Federation of Skull Base Societies.

    Dr. Karadimas is a fellow of the Royal College of Surgeons of Canada and American Association of Neurological Surgeons as well as member of the Congress of Neurological Surgeons, and the North American Skull Base Society.

  • Maya M. Kasowski

    Maya M. Kasowski

    Assistant Professor of Pathology, of Medicine (Pulmonary, Allergy and Critical Care Medicine) and, by courtesy, of Genetics

    BioI am a clinical pathologist and assistant professor in the Departments of Medicine, Pathology, and Genetics (by courtesy) at Stanford. I completed my MD-PhD training at Yale University and my residency training and a post-doctoral fellowship in the Department of Genetics at Stanford University. My experiences as a clinical pathologist and genome scientist have made me passionate about applying cutting-edge technologies to primary patient specimens in order to characterize disease pathologies at the molecular level. The core focus of my lab is to study the mechanisms by which genetic variants influence the risk of disease through effects on intermediate molecular phenotypes.

  • Makoto Kawai

    Makoto Kawai

    Clinical Professor, Psychiatry and Behavioral Sciences - Sleep Medicine

    BioI am a physician scientist in the field of sleep medicine in aging and brain function. Using combined polysomnogram and novel neuroimaging technology, I aim to identify potential sleep biomarkers to investigate the mechanism of progression from normal aging to Mild Cognitive Impairment (MCI) or dementia. I also investigate the impact of sleep on cognitive/affective function or behavior abnormality in various neurodevelopmental and neurodegenerative disorders.

  • Mark A. Kay, M.D., Ph.D.

    Mark A. Kay, M.D., Ph.D.

    Dennis Farrey Family Professor of Pediatrics, and Professor of Genetics

    Current Research and Scholarly InterestsMark A. Kay, M.D., Ph.D. Director of the Program in Human Gene Therapy and Professor in the Departments of Pediatrics and Genetics. Respected worldwide for his work in gene therapy for hemophilia, Dr. Kay and his laboratory focus on establishing the scientific principles and developing the technologies needed for achieving persistent and therapeutic levels of gene expression in vivo. The major disease models are hemophilia, hepatitis C, and hepatitis B viral infections.

  • Corey Keller, MD, PhD

    Corey Keller, MD, PhD

    Associate Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)

    Current Research and Scholarly InterestsThe goal of my lab is to understand the fundamental principles of human brain plasticity and build trans-diagnostic real-time monitoring platforms for personalized neurotherapeutics.

    We use an array of neuroscience methods to better understand the basic principles of how to create change in brain circuits. We use this knowledge to develop more effective treatment strategies for depression and other psychiatric disorders.

  • Kevin Kelley

    Kevin Kelley

    Assistant Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology)

    BioAs a neuroscientist and psychiatrist, I am motivated by how little we understand about the pathophysiology of psychiatric disorders and hope that further knowledge will help to alleviate the ongoing distress of many of our patients. My research program leverages computational genomics, human brain cellular models, and molecular neuroscience techniques to understand the cellular and molecular mechanisms of human brain development and how dysfunction in these processes lead to psychiatric disorders.

  • Oussama Khatib

    Oussama Khatib

    Weichai Professor and Professor, by courtesy, of Electrical Engineering

    BioRobotics research on novel control architectures, algorithms, sensing, and human-friendly designs for advanced capabilities in complex environments. With a focus on enabling robots to interact cooperatively and safely with humans and the physical world, these studies bring understanding of human movements for therapy, athletic training, and performance enhancement. Our work on understanding human cognitive task representation and physical skills is enabling transfer for increased robot autonomy. With these core capabilities, we are exploring applications in healthcare and wellness, industry and service, farms and smart cities, and dangerous and unreachable settings -- deep in oceans, mines, and space.

  • Chaitan Khosla

    Chaitan Khosla

    Wells H. Rauser and Harold M. Petiprin Professor and Professor of Chemistry and, by courtesy, of Biochemistry

    Current Research and Scholarly InterestsResearch in this laboratory focuses on problems where deep insights into enzymology and metabolism can be harnessed to improve human health.

    For the past two decades, we have studied and engineered enzymatic assembly lines called polyketide synthases that catalyze the biosynthesis of structurally complex and medicinally fascinating antibiotics in bacteria. An example of such an assembly line is found in the erythromycin biosynthetic pathway. Our current focus is on understanding the structure and mechanism of this polyketide synthase. At the same time, we are developing methods to decode the vast and growing number of orphan polyketide assembly lines in the sequence databases.

    For more than a decade, we have also investigated the pathogenesis of celiac disease, an autoimmune disorder of the small intestine, with the goal of discovering therapies and related management tools for this widespread but overlooked disease. Ongoing efforts focus on understanding the pivotal role of transglutaminase 2 in triggering the inflammatory response to dietary gluten in the celiac intestine.

  • Butrus Khuri-Yakub

    Butrus Khuri-Yakub

    Professor (Research) of Electrical Engineering, Emeritus

    BioButrus (Pierre) T. Khuri-Yakub is a Professor of Electrical Engineering at Stanford University. He received the BS degree from the American University of Beirut, the MS degree from Dartmouth College, and the Ph.D. degree from Stanford University, all in electrical engineering. His current research interests include medical ultrasound imaging and therapy, ultrasound neuro-stimulation, chemical/biological sensors, gas flow and energy flow sensing, micromachined ultrasonic transducers, and ultrasonic fluid ejectors. He has authored over 600 publications and has been principal inventor or co-inventor of 107 US and international issued patents. He was awarded the Medal of the City of Bordeaux in 1983 for his contributions to Nondestructive Evaluation, the Distinguished Advisor Award of the School of Engineering at Stanford University in 1987, the Distinguished Lecturer Award of the IEEE UFFC society in 1999, a Stanford University Outstanding Inventor Award in 2004, Distinguished Alumnus Award of the School of Engineering of the American University of Beirut in 2005, Stanford Biodesign Certificate of Appreciation for commitment to educate, mentor and inspire Biodesgin Fellows, 2011, and 2011 recipient of IEEE Rayleigh award.

  • Mathew Kiang

    Mathew Kiang

    Assistant Professor of Epidemiology and Population Health (Epidemiology)

    BioI am an assistant professor in the Department of Epidemiology and Population Health. My research lies at the intersection of computational epidemiology and social epidemiology. Methodologically, my work revolves around combining disparate data sources in epidemiologically meaningful ways. For example, I work with individual-level, non-health data (e.g., GPS, accelerometer, and other sensor data from smartphones), traditional health data (e.g., survey, health systems, or death certificate data), and third-party data (e.g., cellphone providers or ad-tech data). To do this, I use a variety of methods such as joint Bayesian spatial models, traditional epidemiologic models, dynamical models, microsimulation, and demographic analysis. Substantively, my work focuses on socioeconomic and racial/ethnic inequities, substance use, and child health. For example, recently, my work has examined inequities in COVID-19 vaccine distribution, cause-specific excess mortality, and drug poisonings. Other work has examined the impact of changing vaccination rates on the reemergence of infectious diseases and the prevalence of parental death among children.

  • Peter S. Kim

    Peter S. Kim

    Virginia and D. K. Ludwig Professor of Biochemistry

    Current Research and Scholarly InterestsOur research focuses on developing new strategies for vaccine creation. We also aim to generate vaccines targeting infectious agents that have eluded efforts to date. We integrate experimental approaches with protein language models to guide artificial evolution and enable efficient antibody and protein engineering. Our interdisciplinary approach aims to address critical global health challenges.

  • Seung K. Kim  M.D., Ph.D.

    Seung K. Kim M.D., Ph.D.

    KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
    On Partial Leave from 09/16/2025 To 03/31/2026

    Current Research and Scholarly InterestsWe study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.

  • Benyam Z. Kinde, MD, PhD

    Benyam Z. Kinde, MD, PhD

    Assistant Professor of Ophthalmology

    BioDr. Kinde is a board-certified, fellowship-trained ophthalmologist and ophthalmic plastic and reconstructive surgeon at Stanford Health Care Byers Eye Institute. He is also an assistant professor in the Department of Ophthalmology at Stanford University School of Medicine. Dr. Kinde completed the American Society of Ophthalmic and Plastic Reconstructive Surgery (ASOPRS) fellowship in ophthalmic plastic surgery through the Bascom Palmer Eye Institute at the University of Miami.

    Dr. Kinde diagnoses and treats a wide range of conditions related to the eyelid and other eye structures, including facial nerve palsy, skin cancer, and thyroid eye disease. He also provides care for patients who wish to enhance their appearance through surgical and nonsurgical interventions. Dr. Kinde offers many types of treatments, including cosmetic surgery, eyelid surgery (including upper and lower eyelid blepharoplasty and ptosis surgery), reconstructive surgery, tear duct (lacrimal) surgery, and orbital surgery.

    Dr. Kinde is a physician-scientist whose research interests focus on developing new tools to promote survival of retinal ganglion cells after optic nerve injury. He has investigated how modulating the DNA damage response in mouse models of traumatic optic neuropathy (symptoms of nerve damage) may promote and improve optic nerve function after injury. His previous work focused on increasing the resilience of neurons (messaging nerve cells) in mouse models of glaucoma and in humans with glaucoma. He completed his MD and PhD in neuroscience at Harvard Medical School, where his thesis work revealed a new understanding of Rett syndrome, a rare genetic disorder that affects body movement.

    Dr. Kinde has published in many peer-reviewed journals, including Nature, Science, Cell, Ophthalmology, and Facial Plastic Surgery & Aesthetic Medicine. He has presented to his peers at international and national meetings, including the Association for Research in Vision and Ophthalmology, American Society of Ophthalmic Plastic and Reconstructive Surgery, and Inter-American Course in Clinical Ophthalmology.

  • David Kingsley

    David Kingsley

    Rudy J. and Daphne Donohue Munzer Professor in the School of Medicine

    Current Research and Scholarly InterestsWe use mice, stickleback fish, and humans to study the molecular basis of evolution and common diseases. By combining genetics and genomics, we have identified key DNA changes that control bone formation, limb patterning, hair color, brain evolution, and susceptibility to arthritis, schizophrenia, and bipolar disorder. We find that the same genetic mechanisms are often used repeatedly in nature, providing new insights into the origin of key traits in many different species, including ourselves.

  • Amanda Kirane, MD, PhD, FACS, FSSO

    Amanda Kirane, MD, PhD, FACS, FSSO

    Associate Professor of Surgery (General Surgery)

    BioDr. Kirane is a fellowship-trained, board-certified specialist in complex general surgical oncology. She is an Assistant Professor in the Department of Surgery, Section of Surgical Oncology, at Stanford University School of Medicine. Dr. Kirane serves as Director of Cutaneous Surgical Oncology at the Stanford Cancer Center and her clinical practice focuses on the diagnosis and treatment of melanoma and other skin cancers. She partners closely with patients and families to provide the most effective treatment approach possible. For each patient, she tailors an evidence-based, personalized care plan that is innovative, comprehensive, and compassionate.

    Dr. Kirane is Principal Investigator of multiple studies in melanoma and mechanisms of resistance to immunotherapy, with focus on myeloid biology. Her current interests include immune response and novel therapies in melanoma, predictive modeling of patient responses using organoid technology, and translational biomarker development. She has led research into immune therapy for earlier stage melanoma using regionally directed therapy to augment immune response in melanoma and trials in surgical care in melanoma.

    The National Institutes of Health, American Society of Clinical Oncology, the Melanoma Research Alliance, and others have funded her research. She has co-authored articles on her discoveries in the Journal of Clinical Investigation, Nature Communications, Nature Genetics, Cancer Research, Journal of Surgical Oncology, Annals of Surgery, Annals of Surgical Oncology, and elsewhere. Topics include intratumoral therapy, biomarker development, macrophage biology in melanoma and immunotheraputic resistance, and patient-derived organoid modeling. Dr. Kirane has presented updates on the management of melanoma and other cancers to her peers at meetings of the American College of Surgeons, Society of Surgical Oncology, and Society for Immunotherapy in Cancer.

    Dr. Kirane has earned awards for her achievements in clinical care, research, and scholarship. The Society for Immunotherapy of Cancer, Society of Surgical Oncology, Memorial Sloan Kettering Cancer Center, and other prestigious organizations have honored her work. She is a fellow of the American College of Surgeons (FACS) and Society of Surgical Oncology (FSSO). She is a member of the Society for Immunotherapy of Cancer, American Association of Cancer Research, Society for Melanoma Research, Connective Tissue Oncology Society, Association of Academic Surgeons, and Association of Women Surgeons.

    She volunteers her time and expertise on behalf of the Melanoma Research Foundation, members of her community in need, STEM programs for girls, and other initiatives. She also is fellowship trained in Physician Wellness and Wellbeing and teaches somatic technique, mindfulness-based stress reduction, meditation, and breathwork.

  • Juliet Klasing Knowles

    Juliet Klasing Knowles

    Assistant Professor of Neurology and Neurological Sciences (Pediatric Neurology) and of Pediatrics

    Current Research and Scholarly InterestsThe Knowles lab studies how white matter structure changes in different forms of epilepsy, and how aberrant white matter structure, in turn, shapes neuronal network function. In mouse models, we use a variety of innovative tools including neurophysiology, quantitative EEG, behavior, histological measures of white matter structure and MR imaging. We also conduct clinical research to study white matter abnormalities in children with epilepsy.

  • Eric I. Knudsen

    Eric I. Knudsen

    Edward C. and Amy H. Sewall Professor in the School of Medicine, Emeritus

    Current Research and Scholarly InterestsCellular mechanisms of spatial attention and learning, studied in the central nervous system in birds, using behavioral, systems, cellular and molecular techniques.

  • Brian Knutson

    Brian Knutson

    Professor of Psychology

    Current Research and Scholarly InterestsMy lab and I seek to elucidate the neural basis of emotion (affective neuroscience), and explore implications for decision-making (neuroeconomics) and psychopathology (neurophenomics).

  • Brian Kobilka

    Brian Kobilka

    Hélène Irwin Fagan Chair of Cardiology

    Current Research and Scholarly InterestsStructure, function and physiology of adrenergic receptors.

  • Mykel Kochenderfer

    Mykel Kochenderfer

    Associate Professor of Aeronautics and Astronautics, Senior Fellow at the Stanford Institute for Human-Centered AI and Associate Professor, by courtesy, of Computer Science

    BioMykel Kochenderfer is Associate Professor of Aeronautics and Astronautics at Stanford University. Prior to joining the faculty, he was at MIT Lincoln Laboratory where he worked on airspace modeling and aircraft collision avoidance, with his early work leading to the establishment of the ACAS X program. He received a Ph.D. from the University of Edinburgh and B.S. and M.S. degrees in computer science from Stanford University. Prof. Kochenderfer is the director of the Stanford Intelligent Systems Laboratory (SISL), conducting research on advanced algorithms and analytical methods for the design of robust decision making systems. Of particular interest are systems for air traffic control, unmanned aircraft, and other aerospace applications where decisions must be made in uncertain, dynamic environments while maintaining safety and efficiency. Research at SISL focuses on efficient computational methods for deriving optimal decision strategies from high-dimensional, probabilistic problem representations. He is an author of "Decision Making under Uncertainty: Theory and Application" (2015), "Algorithms for Optimization" (2019), and "Algorithms for Decision Making" (2022), all from MIT Press. He is a third generation pilot.

  • Eric Kool

    Eric Kool

    George A. and Hilda M. Daubert Professor of Chemistry

    Current Research and Scholarly Interests• Design of cell-permeable reagents for profiling, modifying, and controlling RNAs
    • Developing fluorescent probes of DNA repair pathways, with applications in cancer, aging, and neurodegenerative disease
    • Discovery and development of small-molecule modulators of DNA repair enzymes, with focus on cancer and inflammation

  • Ron Kopito

    Ron Kopito

    Professor of Biology

    Current Research and Scholarly InterestsOur laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.