Bio-X


Showing 1-70 of 70 Results

  • Michele Calos

    Michele Calos

    Professor of Genetics, Emerita

    Current Research and Scholarly InterestsMy lab is developing innovative gene and stem cell therapies for genetic diseases, with a focus on gene therapy and regenerative medicine.

    We have created novel methods for inserting therapeutic genes into the chromosomes at specific places by using homologous recombination and recombinase enzymes.

    We are working on 3 forms of muscular dystrophy.

    We created induced pluripotent stem cells from patient fibroblasts, added therapeutic genes, differentiated, and engrafted the cells.

  • David Camarillo

    David Camarillo

    Assistant Professor of Bioengineering and, by courtesy, of Neurosurgery and of Mechanical Engineering

    BioDavid B. Camarillo is Assistant Professor of Bioengineering, (by courtesy) Mechanical Engineering and Neurosurgery at Stanford University. Dr. Camarillo holds a B.S.E in Mechanical and Aerospace Engineering from Princeton University, a Ph.D. in Mechanical Engineering from Stanford University and completed postdoctoral fellowships in Biophysics at the UCSF and Biodesign Innovation at Stanford. Dr. Camarillo worked in the surgical robotics industry at Intuitive Surgical and Hansen Medical, before launching his laboratory at Stanford in 2012. His current research focuses on precision human measurement for multiple clinical and physiological areas including the brain, heart, lungs, and reproductive system. Dr. Camarillo has been awarded the Hellman Fellowship, the Office of Naval Research Young Investigator Program award, among other honors including multiple best paper awards in brain injury and robotic surgery. His research has been funded by the NIH, NSF, DoD, as well as corporations and private philanthropy. His lab’s research has been featured on NPR, the New York Times, The Washington Post, Science News, ESPN, and TED.com as well as other media outlets aimed at education of the public.

  • Emmanuel Candes

    Emmanuel Candes

    Barnum-Simons Chair in Math and Statistics, and Professor of Statistics and, by courtesy, of Electrical Engineering

    BioEmmanuel Candès is the Barnum-Simons Chair in Mathematics and Statistics, a professor of electrical engineering (by courtesy) and a member of the Institute of Computational and Mathematical Engineering at Stanford University. Earlier, Candès was the Ronald and Maxine Linde Professor of Applied and Computational Mathematics at the California Institute of Technology. His research interests are in computational harmonic analysis, statistics, information theory, signal processing and mathematical optimization with applications to the imaging sciences, scientific computing and inverse problems. He received his Ph.D. in statistics from Stanford University in 1998.

    Candès has received several awards including the Alan T. Waterman Award from NSF, which is the highest honor bestowed by the National Science Foundation, and which recognizes the achievements of early-career scientists. He has given over 60 plenary lectures at major international conferences, not only in mathematics and statistics but in many other areas as well including biomedical imaging and solid-state physics. He was elected to the National Academy of Sciences and to the American Academy of Arts and Sciences in 2014.

  • Robson Capasso

    Robson Capasso

    Associate Professor of Otolaryngology-Head and Neck Surgery (Sleep Surgery) at the Stanford University Medical Center

    Current Research and Scholarly InterestsClinically relevant outcomes for OSA Surgery.
    Wearables and Digital Health Technologies for Sleep.
    Innovative approaches for OSA Management.
    Innovation in Sleep and Otolaryngology

  • Jan Carette

    Jan Carette

    Associate Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsOur research focuses on the identification of host genes that play critical roles in the pathogenesis of infectious agents including viruses. We use haploid genetic screens in human cells as an efficient approach to perform loss-of-function studies. Besides obtaining fundamental insights on how viruses hijack cellular processes and on host defense mechanisms, it may also facilitate the development of new therapeutic strategies.

  • Victor Carrion

    Victor Carrion

    John A. Turner Endowed Professor for Child and Adolescent Psychiatry

    Current Research and Scholarly InterestsExamines the interplay between brain development and stress vulnerability via a multi-method approach that includes psychophysiology, neuroimaging, neuroendocrinology and phenomenology. Treatment development that focuses on individual and community-based interventions for stress related conditions in children and adolescents that experience traumatic stress.

  • Dennis R Carter

    Dennis R Carter

    Professor of Mechanical Engineering, Emeritus

    Current Research and Scholarly InterestsProfessor Carter studies the influence of mechanical loading upon the growth, development, regeneration, and aging of skeletal tissues. Basic information from such studies is used to understand skeletal diseases and treatments. He has served as President of the Orthopaedic Research Society and is a Fellow of the American Institute for Medical and Biological Engineering.

  • Lynette Cegelski

    Lynette Cegelski

    Associate Professor of Chemistry and, by courtesy, of Chemical Engineering

    Current Research and Scholarly InterestsOur research program integrates chemistry, biology, and physics to investigate the assembly and function of macromolecular and whole-cell systems. The genomics and proteomics revolutions have been enormously successful in generating crucial "parts lists" for biological systems. Yet, for many fascinating systems, formidable challenges exist in building complete descriptions of how the parts function and assemble into macromolecular complexes and whole-cell factories. We are inspired by the need for new and unconventional approaches to solve these outstanding problems and to drive the discovery of new therapeutics for human disease.

    Our approach is different from the more conventional protein-structure determinations of structural biology. We employ biophysical and biochemical tools, and are designing new strategies using solid-state NMR spectroscopy to examine assemblies such as amyloid fibers, bacterial cell walls, whole cells, and biofilms. We would like to understand at a molecular and atomic level how bacteria self-assemble extracellular structures, including functional amyloid fibers termed curli, and how bacteria use such building blocks to construct organized biofilm architectures. We also employ a chemical genetics approach to recruit small molecules as tools to interrupt and interrogate the temporal and spatial events during assembly processes and to develop new strategies to prevent and treat infectious diseases. Overall, our approach is multi-pronged and provides training opportunities for students interested in research at the chemistry-biology interface.

  • Chris Chafe

    Chris Chafe

    Duca Family Professor

    BioChris Chafe is a composer, improvisor and cellist, developing much of his music alongside computer-based research. He is Director of Stanford University's Center for Computer Research in Music and Acoustics (CCRMA). At IRCAM (Paris) and The Banff Centre (Alberta), he pursued methods for digital synthesis, music performance and real-time internet collaboration. CCRMA's SoundWIRE project involves live concertizing with musicians the world over. Online collaboration software including jacktrip and research into latency factors continue to evolve. An active performer either on the net or physically present, his music reaches audiences in dozens of countries and sometimes at novel venues. A simultaneous five-country concert was hosted at the United Nations in 2009. Chafe's works are available from Centaur Records and various online media. Gallery and museum music installations are into their second decade with "musifications" resulting from collaborations with artists, scientists and MD's. Recent works include Tomato Quintet for the transLife:media Festival at the National Art Museum of China, Phasor for contrabass and Sun Shot played by the horns of large ships in the port of St. Johns, Newfoundland. Chafe premiered DiPietro's concerto, Finale, for electric cello and orchestra in 2012.

  • Page Chamberlain

    Page Chamberlain

    Professor of Geological Sciences

    Current Research and Scholarly InterestsResearch
    I use stable and radiogenic isotopes to understand Earth system history. These studies examine the link between climate, tectonics, biological, and surface processes. Projects include: 1) examining the terrestrial climate history of the Earth focusing on periods of time in the past that had CO 2-levels similar to the present and to future projections; and 2) addressing how the chemical weathering of the Earth's crust affects both the long- and short-term carbon cycle. Field areas for these studies are in the Cascades, Rocky Mountains, Sierra Nevada, the European Alps, Tibet and the Himalaya and the Southern Alps of New Zealand.

    Teaching
    I teach courses at the undergraduate and graduate level in isotope biogeochemistry, Earth system history, and the relationship between climate, surface processes and tectonics. I also teach a three-week field course each September in the Wind River Mountains of Wyoming for sophomores and GES majors. This course covers topics in environmental and geological sciences.

    Professional Activities
    Editor American Journal of Science; Co-Director Stanford Stable Isotope Biogeochemistry Laboratory (present);Chair, Department of Geological and Environmental Sciences (2004-07); Co-Director Stanford/USGS SHRIMP Ion microprobe facility (2001-04)

  • Daniel Chang

    Daniel Chang

    Sue and Bob McCollum Professor

    Current Research and Scholarly InterestsI specialize in the treatment of gastrointestinal malignancies. I am interested in developing stereotactic body radiotherapy for tumors of the liver, both primary and metastatic. I am interested in developing functional imaging as a means of determining treatment response with radiation. I am also interested in developing image-guided radiotherapy to improve radiation delivery for GI cancers to reduce toxicity and improve disease outcome.

  • Fu-Kuo Chang

    Fu-Kuo Chang

    Professor of Aeronautics and Astronautics

    BioProfessor Chang's primary research interest is in the areas of multi-functional materials and intelligent structures with particular emphases on structural health monitoring, intelligent self-sensing diagnostics, and integrated health management for space and aircraft structures as well safety-critical assets and medical devices. His specialties include sensors and sensor network development, built-in self-diagnostics,  integrated diagnostics and prognostics, damage tolerance and failure analysis for composite materials, and advanced multi-physics computational methods for multi-functional structures. Most of his work involves system integration and multi-disciplinary engineering in structural mechanics, electrical engineering, signal processing, and multi-scale fabrication of materials. His recent research topics include: Integrated health management for aircraft structures, bio-inspired intelligent sensory materials for fly-by-feel autonomous vehicles, active sensing diagnostics for composite structures, self-diagnostics for high-temperature materials, etc.

  • Howard Y. Chang, MD, PhD

    Howard Y. Chang, MD, PhD

    Virginia and D. K. Ludwig Professor of Cancer Genomics and of Genetics

    Current Research and Scholarly InterestsOur research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.

  • James Chang, MD

    James Chang, MD

    Johnson and Johnson Professor of Surgery and Professor, by courtesy, of Orthopaedic Surgery at the Palo Alto Veterans Affairs Health Care System

    Current Research and Scholarly InterestsMy role in research is to apply novel advances in tissue engineering and microsurgery to the clinical problems of hand trauma, peripheral nerve injuries, and congenital hand problems. I am interested in developing new tissues and techniques that will allow optimal reconstruction of form and function to those patients requiring reconstructive surgery.

  • Robert Chang

    Robert Chang

    Assistant Professor of Ophthalmology at the Stanford University Medical Center

    Current Research and Scholarly InterestsI'm interested in digital health, commercialization of new technology, and the biodesign education process. I have expertise in mobile health and clinical validation of new eye care devices.

  • Steven D. Chang, MD

    Steven D. Chang, MD

    Robert C. and Jeannette Powell Neurosciences Professor and, by courtesy, of Otolaryngology-Head and Neck Surgery and of Neurology

    Current Research and Scholarly InterestsClinical research includes studies in the treatment of cerebrovascular disorders, such as aneurysms and AVMs, as well as the use of radiosurgery to treat tumors and vascular malformations of the brain and spine.

    Dr. Chang is C0-Director of the Cyberknife Radiosurgery Program.

    Dr. Chang is also the head of the The Stanford Neuromolecular Innovation Program with the goal of developing new technologies to improve the diagnosis and treatment of patients affected by neurological conditions.

  • Ovijit Chaudhuri

    Ovijit Chaudhuri

    Assistant Professor of Mechanical Engineering

    BioOur group's research is focused at the intersection of mechanics and biology. We are interested in elucidating the underlying molecular mechanisms that give rise to the complex mechanical properties of cells, extracellular matrices, and tissues . Conversely, we are investigating how complex mechanical cues influence important biological processes such as cell division, differentiation, or cancer progression. Our approaches involve using force measurement instrumentation, such as atomic force microscopy, to exert and measure forces on materials and cells at the nanoscale, and the development of material systems for 3D cell culture that allow precise and independent manipulation of mechanical properties.

  • Bertha Chen, MD

    Bertha Chen, MD

    Professor of Obstetrics and Gynecology (Gynecology - Urogynecology) and, by courtesy, of Urology at the Stanford University Medical Center

    Current Research and Scholarly InterestsDr. Chen’s research examines the molecular causes of urinary incontinence and pelvic floor dysfunction. Recognizing that urinary incontinence linked to demise of smooth muscle sphincter function, she is investigating the potential use of stem cell regeneration to restore muscle capacity.

  • James K. Chen

    James K. Chen

    Professor of Chemical and Systems Biology, of Developmental Biology and of Chemistry

    Current Research and Scholarly InterestsOur laboratory combines chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.

  • Jonathan H. Chen, MD, PhD

    Jonathan H. Chen, MD, PhD

    Assistant Professor of Medicine (Biomedical Informatics) at the Stanford University Medical Center

    Current Research and Scholarly InterestsInformatics solutions ares the only credible approach to systematically address challenges of escalating complexity in healthcare. Tapping into real-world clinical data streams like electronic medical records will reveal the community's latent knowledge in a reproducible form. Delivering this back as clinical decision support will uniquely close the loop on a continuously learning health system.

  • Lu Chen

    Lu Chen

    Professor of Neurosurgery and of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsWhat distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation.

  • Xiaoke Chen

    Xiaoke Chen

    Associate Professor of Biology

    Current Research and Scholarly InterestsOur goal is to understand how brain circuits mediate motivated behaviors, and how maladaptive changes in these circuits cause mood disorders. To achieve this goal, we focus on studying the neural circuits for pain and addiction, as both trigger highly motivated behaviors, whereas, transitioning from acute to chronic pain or from recreational to compulsive drug use involves maladaptive changes of the underlying neuronal circuitry.

  • Alan G. Cheng

    Alan G. Cheng

    Associate Professor of Otolaryngology - Head and Neck Surgery (Pediatrics) and, by courtesy, of Pediatrics

    Current Research and Scholarly InterestsActive Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated. Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage.

  • Zhen Cheng

    Zhen Cheng

    Associate Professor (Research) of Radiology (Molecular Imaging)

    Current Research and Scholarly InterestsTo develop novel molecular imaging probes and techniques for non-invasively early detection of cancer using multimodality imaging technologies including PET, SPECT, MRI, optical imaging, etc.

  • Thomas L. Cherpes, DVM, MD

    Thomas L. Cherpes, DVM, MD

    Assistant Professor of Comparative Medicine

    Current Research and Scholarly InterestsDirects an infectious disease laboratory that performs basic, translational, and clinical research. Laboratory has particular focus on:
    1) relationship between exogenous sex steroids on susceptibility to microbial pathogens
    2) role of Type 2 immunity in Chlamydia infection
    3) developing cellular immunotherapies to combat infectious disease and cancer

  • Mike Cherry

    Mike Cherry

    Professor (Research) of Genetics

    Current Research and Scholarly InterestsMy research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education. Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments. The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research.

  • Emilie Cheung, MD

    Emilie Cheung, MD

    Associate Professor of Orthopaedic Surgery at the Stanford University Medical Center

    Current Research and Scholarly InterestsPyrocarbon humeral head replacement
    Clinical outcome after shoulder replacement
    Clinical outcome after elbow replacement
    Clinical outcomes following complex reconstruction of the shoulder and elbow,
    Bone mineral density in the shoulder,
    3D kinematics of the shoulder girdle after arthroplasty

  • E.J. Chichilnisky

    E.J. Chichilnisky

    John R. Adler Professor, Professor of Neurosurgery and of Ophthalmology and, by courtesy, of Electrical Engineering

    Current Research and Scholarly InterestsFunctional circuitry of the retina and design of retinal prostheses

  • Frederick T. Chin, Ph.D.

    Frederick T. Chin, Ph.D.

    Assistant Professor (Research) of Radiology (Molecular Imaging)

    Current Research and Scholarly InterestsOur group's primary objectives are:

    1) Novel radioligand and radiotracer development.
    We will develop novel PET (Positron Emission Tomography) imaging agents with MIPS and Stanford faculty as well as other outside collaborations including academia and pharmaceutical industry. Although my personal research interests will be to discover and design of candidate probes that target molecular targets in the brain, our group focus will primarily be on cancer biology and gene therapy. In conjunction with our state-of-the-art imaging facility, promising candidates will be evaluated by PET-CT/MR imaging in small animals and primates. Successful radioligands and/or radiotracers will be extended towards future human clinical applications.

    2) Designing new radiolabeling techniques and methodologies.
    We will aim to design new radiolabeling techniques and methodologies that may have utility for future radiopharmaceutical development in our lab and the general radiochemistry community.

    3) Radiochemistry production of routine clinical tracers.
    Since we also have many interests with many Stanford faculty and outside collaborators, our efforts will also include the routine radiochemistry production of many existing radiotracers for human and non-human use. Our routine clinical tracers will be synthesized in custom-made or commercial synthetic modules (i.e. GE TRACERlab modules) housed in lead-shielded cells and be distributed manually or automatically (i.e. Comecer Dorothea) to our imagers.

  • Bill Chiu

    Bill Chiu

    Associate Professor of Surgery (Pediatric Surgery) at the Stanford University Medical Center

    BioDr. Chiu obtained his B.S. degree in Biological Sciences and graduated with Honors from Stanford University. After graduating, he received his Medical Degree at Northwestern University Feinberg School of Medicine, where he remained for his internship and General Surgery residency training. Dr. Chiu completed his Pediatric Surgery training at The Children’s Hospital of Philadelphia. He is an Associate Professor at Stanford University School of Medicine where he has an active research program studying innovative approaches to treat patients with neuroblastoma.

  • Wah Chiu

    Wah Chiu

    Professor of Photon Science, Bioengineering and of Microbiology and Immunology

    Current Research and Scholarly InterestsMy research include methodology improvements in single particle cryo-EM for atomic resolution structure determination of molecules and molecular machines, as well as in cryo-ET of cells and organelles towards subnanometer resolutions. We have collaborations with many researchers around the country and outside USA on understanding biological processes such as protein folding, virus assembly and disassembly, pathogen-host interactions, signal transduction, transport across cytosol and membrane.

  • Constance Chu, MD

    Constance Chu, MD

    Professor of Orthopaedic Surgery (Sports Medicine) at the Palo Alto Veterans Affairs Health Care System

    BioDr. Constance R. Chu is Professor and Vice Chair Research, in the Department of Orthopedic Surgery at Stanford University. She is also Director of the Joint Preservation Center and Chief of Sports Medicine at the VA Palo Alto. Previously, she was the Albert Ferguson Endowed Chair and Professor of Orthopaedic Surgery at the University of Pittsburgh. She is a clinician-scientist who is both principal investigator of several projects funded by the National Institutes of Health and who has been recognized as a Castle-Connelly/US News and World Report “Top Doctor” in Orthopedic Surgery as well as on Becker’s list of Top Knee Surgeons in the United States. Her clinical practice focuses on the knee: primarily restoration and reconstruction of the ACL, menisci and cartilage. She graduated from the U.S. Military Academy at West Point and earned her medical degree from Harvard Medical School.

    As Director of the multi-disciplinary Joint Preservation Center structured to seamlessly integrate the latest advances in biologics, mechanics, and imaging with comprehensive patient centered musculoskeletal and orthopedic care, Dr. Chu aims to develop a new model for health care delivery, research and education with an emphasis on health promotion and prevention. Cornerstones of this program include teamwork and a focus on personalized medicine. A central goal is to transform the clinical approach to osteoarthritis from palliation to prevention. In addition to optimizing clinical operations, outstanding research is critical to developing more effective new treatments. Towards this end, Dr. Chu is leading innovative translational research from bench to bedside in three main areas: quantitative imaging and biomarker development for early diagnosis and staging of joint and cartilage injury and degeneration; cartilage tissue engineering and stem cell based cartilage repair; and molecular and biological therapies for joint restoration and joint rejuvenation. Her research efforts have led to more than 30 professional awards and honors to include a Kappa Delta Award, considered to be the highest research honor in Orthopedic Surgery.

    Dr. Chu also regularly holds leadership and committee positions in major professional organizations such as the American Association of Orthopedic Surgeons (AAOS) and the American Orthopedic Association (AOA). In her subspecialty of Orthopedic Sports Medicine, she is a past President of the Forum Sports Focus Group, a member of the Herodicus Society of leaders in Sports Medicine, and immediate past Chair of the American Orthopedic Society for Sports Medicine (AOSSM) Research Council. She is alumnus of the AOA American, British, Canadian (ABC) and the AOSSM Traveling Fellowships.

  • Gilbert Chu

    Gilbert Chu

    Professor of Medicine (Oncology) and of Biochemistry

    Current Research and Scholarly InterestsOur laboratory seeks to understand how cells repair DNA damage. We currently focus on how non-homologous end joining proteins assemble on DNA ends to juxtapose them for repair of DNA double-strand breaks.

    We are collaborating on a point-of-care device to measure ammonia from a drop of blood. The device will facilitate diagnosis and management of urea cycle defects, liver disease, and chemobrain due to elevated ammonia.

  • Lawrence Chu, MD, MS

    Lawrence Chu, MD, MS

    Professor of Anesthesiology, Perioperative and Pain Medicine at the Stanford University Medical Center

    Current Research and Scholarly InterestsI have two lines of research, one involving educational informatics and use of technology in postgraduate medical education and another involving NIH-funded work in patient-oriented clinical research regarding opioid use and physiologic responses associated with acute and chronic exposure in humans.

    For a full description of my educational informatics work, please see my website aim.stanford.edu.

    My clinical research focuses on the study opiate-induced hyperalgesia in patients suffering from chronic pain.

    I am currently conducting an NIH-funded five year double-blinded randomized controlled clinical study (NIGMS award 1K23GM071400-01) that prospectively examines the following hypotheses: 1) pain patients on chronic opioid therapy develop dose-dependent tolerance and/or hyperalgesia to these medications over time, 2) opiate-induced tolerance and hyperalgesia develop differently with respect to various types of pain, 3) opioid-induced hyperalgesia occurs independently of withdrawal phenomena, and 4) opiate-induced tolerance and hyperalgesia develop differently based on gender and/or ethnicity.

    The study is the first quantitative and prospective examination of tolerance and hyperalgesia in pain patients and may have important implications for the rational use of opioids in the treatment of chronic pain.

  • Steven Chu

    Steven Chu

    William R. Kenan Jr. Professor and Professor of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsSynthesis, functionalization and applications of nanoparticle bioprobes for molecular cellular in vivo imaging in biology and biomedicine. Linear and nonlinear difference frequency mixing ultrasound imaging. Lithium metal-sulfur batteries, new approaches to electrochemical splitting of water. CO2 reduction, lithium extraction from salt water

  • Katrin Chua

    Katrin Chua

    Associate Professor of Medicine (Endocrinology, Gerontology and Metabolism)

    Current Research and Scholarly InterestsOur lab is interested in understanding molecular processes that underlie aging and age-associated pathologies in mammals. We focus on a family of genes, the SIRTs, which regulate stress resistance and lifespan in lower organisms such as yeast, worms, and flies. In mammals, we recently uncovered a number of ways in which SIRT factors may contribute to cellular and organismal aging by regulating resistance to various forms of stress. We have now begun to characterize the molecular mechanisms by which these SIRT factors function. In particular, we are interested in how SIRT factors regulate chromatin, the molecular structure in which the DNA of mammalian genomes is packaged, and how such functions may link genome maintenance to stress resistance and aging.

  • Benjamin I. Chung

    Benjamin I. Chung

    Associate Professor of Urology at the Stanford University Medical Center

    Current Research and Scholarly InterestsRenal cell carcinoma and prostate cancer outcomes research and epidemiology.

  • Karlene Cimprich

    Karlene Cimprich

    Professor of Chemical and Systems Biology

    Current Research and Scholarly InterestsGenomic instability contributes to many diseases, but it also underlies many natural processes. The Cimprich lab is focused on understanding how mammalian cells maintain genomic stability in the context of DNA replication stress and DNA damage. We are interested in the molecular mechanisms underlying the cellular response to replication stress and DNA damage as well as the links between DNA damage and replication stress to human disease.

  • Thomas Clandinin

    Thomas Clandinin

    Shooter Family Professor

    Current Research and Scholarly InterestsThe Clandinin lab focuses on understanding how neuronal circuits assemble and function to perform specific computations and guide behavior. Taking advantage of a rich armamentarium of genetic tools available in the fruit fly, combined with imaging, physiology and analytical techniques drawn from systems neuroscience, we examine a variety of visual circuits.

  • David Clark

    David Clark

    Professor of Anesthesiology, Perioperative and Pain Medicine at the Palo Alto Veterans Affairs Health Care System

    BioAfter completion of training I came to Stanford University in 1998. Since that time I have been involved in a number of clinical and research activities. I oversee the Pain Service at the Palo Alto VA hospital where I am involved in the care of patients with both acute and chronic pain. I am active both in the clinic and on a number of committees dedicated to improving pain management for veterans. Much of my remaining time is spent supervising a research laboratory. There we are pursuing several projects related to the questions of why pain sometimes becomes chronic after injuries and why opioids lose their effectiveness over time when used to treat chronic pain. We would like to find ways to maximize functional recovery after surgery and other forms of trauma while minimizing the risks of analgesic use. This work involves local, national and international collaborations.

  • Michael F. Clarke, M.D.

    Michael F. Clarke, M.D.

    Karel H. and Avice N. Beekhuis Professor in Cancer Biology

    Current Research and Scholarly InterestsDr. Clarke maintains a laboratory focused on two areas of research: i) the control of self-renewal of normal stem cells and diseases such as cancer and hereditary diseases; and ii) the identification and characterization of cancer stem cells. His laboratory is investigating how perturbations of stem cell regulatory machinery contributes to human disease. In particular, the laboratory is investigating epigenetic regulators of self renewal, the process by which stem cells regenerate themselves.

  • Carol Clayberger

    Carol Clayberger

    Professor (Research) of Pediatrics, Emerita

    Current Research and Scholarly InterestsOur group uses molecular biology, biochemistry, and cellular immunology to investigate the activation and effector function of T lymphocytes. Research in the laboratory is currently focused on three areas: granulysin, a lytic molecule expressed late (7-12 days) after T cell activation; identification of correlates of immunity in diseases such as tuberculosis; and tolerance. The long term goal of this work is to develop new ways to treat human disease.

  • William Clusin, MD

    William Clusin, MD

    Associate Professor of Medicine (Cardiovascular Medicine)

    Current Research and Scholarly InterestsCardiac action potentials; tissue culture, voltage, clamp technique; role of calcium in ischemia arrhythmias; coronary, artery disease; myocardial infarction.

  • Maria Inmaculada Cobos Sillero

    Maria Inmaculada Cobos Sillero

    Assistant Professor of Pathology at the Stanford University Medical Center

    Current Research and Scholarly InterestsOur lab uses cellular and molecular methods, single-cell technology, and quantitative histology to study human neurodegenerative diseases. Current projects include:

    - Using single-cell RNA-sequencing to understand selective vulnerability and disease progression in human Alzheimer’s disease brain

    - Investigating mechanisms of tau-related neurodegeneration in human brain

    - Studying the neocortical and limbic systems in Diffuse Lewy Body Disease (DLBD) at the single cell level

  • Jennifer R. Cochran

    Jennifer R. Cochran

    Shriram Chair of Bioengineering, Professor of Bioengineering and, by courtesy, of Chemical Engineering

    Current Research and Scholarly InterestsMolecular Engineering, Protein Biochemistry, Biotechnology, Cell and Tissue Engineering, Molecular Imaging, Chemical Biology

  • Harvey Cohen

    Harvey Cohen

    Deborah E. Addicott - John A. Kriewall and Elizabeth A. Haehl Family Professor in Pediatrics

    Current Research and Scholarly InterestsMy research interests extend from hypothesis-driven studies in biochemistry and cell biology to discovery-driven interests in proteomics and systems biology to clinical treatment of acute lymphoblastic leukemia of children, and pediatric palliative care.

  • Stanley N. Cohen, MD

    Stanley N. Cohen, MD

    Kwoh-Ting Li Professor in the School of Medicine, Professor of Genetics and of Medicine

    Current Research and Scholarly InterestsWe study mechanisms that affect the expression and decay of normal and abnormal mRNAs, and also RNA-related mechanisms that regulate microbial antibiotic resistance. A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of genes.

  • Steven Hartley Collins

    Steven Hartley Collins

    Associate Professor of Mechanical Engineering

    BioSteve Collins received his B.S. in Mechanical Engineering in 2002 from Cornell University, where he performed research on passive dynamic walking robots with Andy Ruina. He received his Ph.D. in Mechanical Engineering in 2008 from the University of Michigan, where he performed research on the dynamics and control of human walking with Art Kuo. He performed postdoctoral research on humanoid robots with Martijn Wisse at T. U. Delft in the Netherlands. He was a professor of Mechanical Engineering and Robotics at Carnegie Mellon University for seven years. In 2017, he joined the faculty of Mechanical Engineering at Stanford University, where he teaches courses on design and robotics and directs the Stanford Biomechatronics Lab.

    Prof. Collins' primary focus is to speed and systematize the design and prescription of prostheses and exoskeletons using versatile device emulator hardware and human-in-the-loop optimization algorithms (Zhang et al. 2017, Science). Another focus is efficient autonomous devices, such as highly energy-efficient walking robots (Collins et al. 2005, Science) and exoskeletons that use no energy yet reduce the metabolic energy cost of human walking (Collins et al. 2015, Nature). He is a member of the Scientific Board of Dynamic Walking and an Associate Editor of the International Journal of Robotics Research. He has received the Young Scientist Award from the American Society of Biomechanics, the Best Medical Devices Paper from the International Conference on Robotics and Automation, and the student-voted Professor of the Year in his department.

  • Le Cong

    Le Cong

    Assistant Professor of Pathology (Pathology Research) and of Genetics

    BioDr. Cong is leading a group in the Department of Pathology and Genetics at Stanford School of Medicine to pursue novel technology for scalable genome editing and single-cell genomics, and accompanying computational approaches inspired by data science. His group has a focus on studying immunology in the context of cancer and neuroscience.

    He obtained his BS with highest honor from Tsinghua University studying Electronic Engineering and then Biology, his Ph.D. from Harvard Medical School co-advised by Drs. Feng Zhang and George Church. He completed doctoral work primarily in Dr. Feng Zhang’s laboratory, where he published seminal studies on harnessing CRISPR/Cas9 for gene editing, including the most highly-cited paper in CRISPR field, with cumulative citation over 15,000 times. He has obtained over 20 issued patents as co-inventor, and his work led to one of the first FDA-approved clinical trials employing viral delivery of CRISPR/Cas9 for in vivo gene therapy. His later work applied single-cell RNA-seq to cancer drug discovery under Dr. Aviv Regev at the Broad Institute with Drs. Tyler Jacks and Vijay Kuchroo.

    Dr. Cong was a Howard Hughes Medical Institute (HHMI) International Fellow, a Cancer Research Institute (CRI) Irvington Fellow, and was selected as Forbes 30 Under 30 Asia list of young innovators, MIT TechReview TR35 China, and 2019 “Top 10 under 40” by GEN (Genetic Engineering & Biotechnology News).

  • Christos E. Constantinou

    Christos E. Constantinou

    Associate Professor of Urology, Emeritus

    Current Research and Scholarly InterestsMy main recent interest is the application of Biomedical Engineering approaches for the clinical visualization and characterization of the static and dynamic properties of pelvic floor function. This extends to ultrasound Imaging and image processing, construction of computer models and biomechanics analysis of pelvic floor function. It is envisioned that these considerations are important constituents of the clinical evaluation of patients with lower urinary tract dysfunction and urodynamics.

  • Christopher H. Contag

    Christopher H. Contag

    Professor of Pediatrics (Neonatology), Emeritus

    Current Research and Scholarly InterestsWe develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in "a vacuum" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult.

  • John P. Cooke, MD, PhD

    John P. Cooke, MD, PhD

    Professor of Medicine (Cardiovascular Medicine), Emeritus

    Current Research and Scholarly InterestsOur translational research program in vascular regeneration is focused on generating and characterizing vascular cells from human induced pluripotential stem cells. We are also studying the therapeutic application of these cells in murine models of peripheral arterial disease. In these studies we leverage our longstanding interest in endothelial signaling, eg by nitric oxide synthase (NOS) as well as by nicotinic cholinergic receptors (nAChR).

  • David N. Cornfield

    David N. Cornfield

    Anne T. and Robert M. Bass Professor in Pediatric Pulmonary Medicine and Professor, by courtesy, of Surgery

    Current Research and Scholarly InterestsOver the past 20 years, the Cornfield Laboratory has focused upon basic, translational and clinical research, with a primary focus on lung biology. As an active clinician-scientist, delivering care to acutely and chronically ill infants and children, our lab focuses on significant clinical challenges and tried to use science to craft novel solutions to difficult clinical problems.

  • Markus Covert

    Markus Covert

    Associate Professor of Bioengineering and, by courtesy, of Chemical and Systems Biology

    Current Research and Scholarly InterestsOur focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors.

  • Tina Cowan

    Tina Cowan

    Professor of Pathology (Clinical) at the Stanford University Medical Center

    Current Research and Scholarly Interestsscreening and diagnosis of patients with inborn errors of metabolism, including newborn screening, development of new testing methods and genotype/phenotype correlations.

  • Gerald Crabtree

    Gerald Crabtree

    Department of Pathology Professor in Experimental Pathology and Professor of Developmental Biology

    Current Research and Scholarly InterestsChromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin in living cells.

  • Craig Criddle

    Craig Criddle

    Professor of Civil and Environmental Engineering and Senior Fellow at the Woods Institute for the Environment

    BioCriddle's research focuses on biotechnology and microbial ecology for clean water, clean energy, and healthy ecosystems.

  • Patricia Cross

    Patricia Cross

    Professor (Teaching) of Structural Biology, Emerita

    Current Research and Scholarly InterestsI am not now actively involved in research, but my past endeavors remain central to my position in guiding medical students in their scholarship pursuits.
    The cited publications represent three areas of interest:
    (1) medical student research (Jacobs and Cross)
    (2) women in medicine (Cross and Steward)
    (3) the reproductive physiology of early development (Cross and Brinster)
    Only one publication is listed in this area since the research is not current, but others (in e.g. Nature, DevBiol, ExpCellRes) give a broader picture of my pursuit when at the University of Pennsylvania.

  • Larry Crowder

    Larry Crowder

    Edward Ricketts Provostial Professor and Senior Fellow at the Woods Institute for the Environment

    Current Research and Scholarly InterestsEcology, conservation, fisheries, protected species, ecosystem-based management

  • Alia Crum

    Alia Crum

    Assistant Professor of Psychology

    Current Research and Scholarly InterestsOur lab focuses on how subjective mindsets (e.g., thoughts, beliefs and expectations) can alter objective reality through behavioral, psychological, and physiological mechanisms. We are interested in understanding how mindsets affect important outcomes both within and beyond the realm of medicine, in the domains such as exercise, diet and stress. https://mbl.stanford.edu/

  • Bianxiao Cui

    Bianxiao Cui

    Associate Professor of Chemistry

    Current Research and Scholarly InterestsWe are developing various physical and chemical approaches to study biological processes in neurons. There are three major research directions: (1) Investigating the axonal transport process using optical imging, magnetic and optical trapping, and microfluidic platform; (2) Developing vertical nanopillar-based electric and optic sensors for sensitive detection of biological functions; (3) Using optogentic approach to investigate temporal and spatial control of intracellular signaling pathways.

  • Yi Cui

    Yi Cui

    Professor of Materials Science and Engineering, of Photon Science, Senior Fellow at the Precourt Institute for Energy and Prof, by courtesy, of Chemistry

    BioCui studies nanoscale phenomena and their applications broadly defined. Research Interests: Nanocrystal and nanowire synthesis and self-assembly, electron transfer and transport in nanomaterials and at the nanointerface, nanoscale electronic and photonic devices, batteries, solar cells, microbial fuel cells, water filters and chemical and biological sensors.

  • Mark R. Cullen, MD

    Mark R. Cullen, MD

    Director, Center for Population Health Sciences, Senior Associate Dean for Research-School of Medicine, Senior Associate Vice Provost, Professor of Medicine, of Biomedical Data Science, of Health Research & Policy & Senior Fellow at SIEPR

    Current Research and Scholarly InterestsSocial and environmental determinants of health; role of workplace physical environment and work organization as causes of chronic disease and disability

  • Catherine Curtin

    Catherine Curtin

    Professor of Surgery (Plastic & Reconstructive Surgery) at the Stanford University Medical Center

    Current Research and Scholarly InterestsMaintaining and optimizing upper limb function in people with spinal cord injury and other nerve disorders.
    Improving pain and general well being after severe hand injuries.
    Improving treatment and recognition of pain.

  • Christina Curtis

    Christina Curtis

    Assistant Professor of Medicine (Oncology) and of Genetics

    Current Research and Scholarly InterestsThe Curtis laboratory is focused on the development and application of innovative experimental, computational, and analytical approaches to improve the diagnosis, treatment, and early detection of cancer.

  • Mark Cutkosky

    Mark Cutkosky

    Fletcher Jones Chair in the School of Engineering

    BioCutkosky applies analyses, simulations, and experiments to the design and control of robotic hands, tactile sensors, and devices for human/computer interaction. In manufacturing, his work focuses on design tools for rapid prototyping.

  • Martha S. Cyert

    Martha S. Cyert

    Dr. Nancy Chang Professor

    Current Research and Scholarly InterestsThe Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.

  • Agnieszka Czechowicz

    Agnieszka Czechowicz

    Assistant Professor of Pediatrics (Stem Cell Transplantation)

    Current Research and Scholarly InterestsDr. Czechowicz’s research is aimed at understanding how hematopoietic stem cells interact with their microenvironment in order to subsequently modulate these interactions to improve bone marrow transplantation and unlock biological secrets that further enable regenerative medicine broadly. This work can be applied across a variety of disease states ranging from rare genetic diseases, autoimmune diseases, solid organ transplantation, microbiome-augmentation and cancer.