Bio-X
Showing 601-620 of 1,080 Results
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Sydney X. Lu
Assistant Professor of Medicine (Hematology)
BioSydney Lu is an assistant professor and physician-scientist in the Division of Hematology, Department of Medicine with a broad interest in both normal and abnormal RNA processing in the context of normal physiology and disease states. The laboratory studies translational questions regarding the mechanistic basis of RNA processing abnormalities in malignant blood disorders, their implications for leukemogenesis and cancer biology, as well as resultant therapeutic opportunities.
As a physician, Sydney’s group is particularly focused on dissecting RNA processing abnormalities in primary patient samples and disease-relevant preclinical model systems. Lab members employ a variety of ‘wet-lab’ and computational approaches to study transcriptome abnormalities in (1) states of immune dysfunction, (2) myeloid blood cancers such as myelodysplastic syndromes and acute myeloid leukemia, and (3) lymphoid blood cancers such as chronic lymphocytic leukemia. Additional projects are focused on novel therapeutics, including multiple targeted agents which modulate RNA processing, for the selective treatment of these diseases.
Sydney’s research is/has been supposed by grant funding from the National Cancer Institute, Parker Institute for Cancer Immunotherapy, Leukemia & Lymphoma Society, Aplastic Anemia & Myelodysplastic Syndromes International Foundation, the American Society for Clinical Oncology, the American Society of Hematology, the American Association for Cancer Research, the Paula and Rodger Riney Foundation, the Doris Duke Charitable Foundation, The Gabrielles Angel Foundation for Cancer Research, and the Stanford Cancer Institute. -
Stephen Luby
Lucy Becker Professor of Medicine, Senior Fellow at the Woods Institute for the Environment, Freeman Spogli Institute for International Studies and Professor, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsDr. Luby’s research interests include identifying and interrupting environmental pathways of disease in low- and middle-income countries.
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Matthew Lungren
Adjunct Professor, Biomedical Data Science
BioDr. Lungren is Chief Data Science Officer for Microsoft Health & Life Sciences where he focuses on translating cutting edge technology, including generative AI and cloud services, into innovative healthcare applications. As a physician and clinical machine learning researcher, he maintains a part-time clinical practice at UCSF while also continuing his research and teaching roles as adjunct professor at Stanford University.
Prior to joining Microsoft, Dr Lungren was a clinical interventional radiologist and research faculty at Stanford University Medical School where he led the Stanford Center for Artificial Intelligence in Medicine and Imaging (AIMI). He later served as Principal for Clinical AI/ML at Amazon Web Services in World Wide Public Sector Healthcare, focusing on business development for clinical machine learning technologies in the public cloud.
His scientific work has led to more than 150 publications, including work on multi-modal data fusion models for healthcare applications, new computer vision and natural language processing approaches for healthcare specific domains, opportunistic screening with machine learning for public health applications, open medical data as public good, prospective clinical trials for clinical AI translation, and application of generative AI in healthcare. He has served as advisor for early stage startups and large fortune-500 companies on healthcare AI technology development and go-to-market strategy. Dr. Lungren's work has been featured in national news outlets such as NPR, Vice News, Scientific American, and he regularly speaks at national and international scientific meetings on the topic of AI in healthcare.
Dr. Lungren is also a top rated instructor on Coursera where his AI in Healthcare course designed especially for learners with non-technical backgrounds has been completed by more than 20k students around the world - enrollment is open now: https://www.coursera.org/learn/fundamental-machine-learning-healthcare -
Mitchell R. Lunn
Associate Professor of Medicine (Nephrology) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsLGBTQIA+ health
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Liqun Luo
Ann and Bill Swindells Professor and Professor, by courtesy, of Neurobiology
Current Research and Scholarly InterestsWe study how neurons are organized into specialized circuits to perform specific functions and how these circuits are assembled during development. We have developed molecular-genetic and viral tools, and are combining them with transcriptomic, proteomic, physiological, and behavioral approaches to study these problems. Topics include: 1) assembly of the fly olfactory circuit; 2) assembly of neural circuits in the mouse brain; 3) organization and function of neural circuits; 4) Tool development.
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Ruben Y. Luo
Assistant Professor of Pathology
Current Research and Scholarly InterestsApply top-down mass spectrometry and label-free immunoassay to the study and utilization of biomarker proteoforms in clinical diagnosis.
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Richard Luthy
Silas H. Palmer Professor of Civil Engineering and Professor, by courtesy, of Oceans
Current Research and Scholarly InterestsDick Luthy studies sustainable solutions to urban water supplies and management of contaminated sediments. Current work includes experimentation and systems-level analysis of innovative, decentralized water reuse and management of urban stormwater for water supply. He is working with a group to assess strategies for coping with reduced water imports and requirements from the State's Water Board to leave more water in California rivers for ecosystems.
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Amelie Lutz
Adjunct Clinical Associate Professor, Radiology
Current Research and Scholarly InterestsMolecular imaging in oncology
Peripheral Nerve Imaging
Cellular imaging of musculoskeletal inflammatory diseases
Kinematic musculoskeletal imaging
Magnetic resonance imaging of hepatic disorders -
Alex Macario MD MBA
Professor of Anesthesiology, Perioperative and Pain Medicine (MSD)
Current Research and Scholarly InterestsDr. Macario studies health care economics & outcomes, with a special focus on surgery and anesthesia. He is well known for helping develop the field of operating room management, and is keenly interested in the cost-effectiveness analyses of drugs and devices. For the past decade Dr. Macario has added medical education as a research priority to better understand methods to best teach students and residents.
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M Bruce MacIver
Professor (Research) of Anesthesiology, Perioperative and Pain Medicine, Emeritus
Current Research and Scholarly InterestsWe study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices.
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Crystal Mackall
Ernest and Amelia Gallo Family Professor and Professor of Pediatrics and of Medicine
Current Research and Scholarly InterestsRecent clinical studies, by us and others, have demonstrated that genetically engineered T cells can eradicate cancers resistant to all other therapies. We are identifying new targets for these therapeutics, exploring pathways of resistance to current cell therapies and creating next generation platforms to overcome therapeutic resistance. We have discovered novel insights into the biology of human T cell exhaustion and developed approaches to prevent and reverse this phenomenon.
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Sean Mackey, M.D., Ph.D.
Redlich Professor, Professor of Anesthesiology, Perioperative, and Pain Medicine (Adult Pain) and, by courtesy, of Neurology and Neurological Sciences
Current Research and Scholarly InterestsMultiple NIH funded projects to characterize CNS mechanisms of human pain. Comparative effectiveness of cognitive behavioral therapy and chronic pain self-management within the context of opioid reduction (PCORI funded). Single session pain catastrophizing treatment: comparative efficacy & mechanisms (NIH R01). Development and implementation of an open-source learning healthcare system, CHOIR (http://choir/stanford.edu), to optimize pain care and innovative research in real-world patients.
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Daniel V. Madison
Professor of Molecular and Cellular Physiology, Emeritus
Current Research and Scholarly InterestsOur underlying forms of activity-dependent synaptic plasticity such as long-term potentiation and long-term depression, and in particular the function and plasticity of Parvalbumin-containing interneurons in neocortex. In the past few years, we have used a combinatorial approach to comparing physiological and anatomical plasticity-induced changes in synapses using electrode recording and Array Tomography in the same neurons.
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Merritt Maduke
Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsMolecular mechanisms of ion chnanels & transporters studied by integration of structural and electrophysiological methods.
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Holden Maecker
Professor (Research) of Microbiology and Immunology
On Partial Leave from 09/15/2024 To 08/31/2025Current Research and Scholarly InterestsI'm interested in immune monitoring of T cell responses to chronic pathogens and cancer, and the correlation of T cell response signatures with disease protection.
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Vinit B. Mahajan, MD, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsOur focus is the development of personalized medicine for eye diseases through translation of our discoveries in proteomics, genomics, and phenomics in humans, mice and tissue culture models.
