Bio-X
Showing 951-960 of 1,057 Results
-
Alice Ting
Professor of Genetics, of Biology and, by courtesy, of Chemistry
Current Research and Scholarly InterestsWe develop chemogenetic and optogenetic technologies for probing and manipulating protein networks, cellular RNA, and the function of mitochondria and the mammalian brain. Our technologies draw from protein engineering, directed evolution, chemical biology, organic synthesis, high-resolution microscopy, genetics, and computational design.
-
Natalie Torok
Professor of Medicine (Gastroenterology and Hepatology)
On Leave from 10/01/2024 To 12/28/2024Current Research and Scholarly InterestsOur lab is focused on exploring the role of matrix remodeling in disease progression in metabolic dysfunction steatohepatitis (MASH)-related hepatocellular carcinoma and primary sclerosing cholangitis. Our goal is to uncover how biomechanical characteristics of the ECM affect mechano-sensation, and how these pathways could ultimately be targeted. We are also interested in aging and its effects on metabolic pathways in MASH and HCC.
-
Philip S. Tsao, PhD
Professor (Research) of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsOur primary interests are in the molecular underpinnings of vascular disease as well as assessing disease risk. In addition to targeted investigation of specific signaling molecules, we utilize global genomic analysis to identify gene expression networks and regulatory units. We are particularly interested in the role of microRNAs in gene expression pathways associated with disease.
-
Richard Tsien
George D. Smith Professor, Emeritus
Current Research and Scholarly InterestsWe study synaptic communication between brain cells with the goal of understanding neuronal computations and memory mechanisms. Main areas of focus include: presynaptic calcium channels, mechanisms of vesicular fusion and recycling. Modulation of synaptic strength through changes in postsynaptic receptors and dendritic morphology. Signaling that links synaptic activity to nuclear transcription and local protein translation. Techniques include imaging, electrophysiology, molecular biology.
-
Jason Tucciarone, MD, PhD
Assistant Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology)
BioJason Tucciarone MD, PhD is an Assistant Professor with Stanford School of Medicine’s Department of Psychiatry and Behavioral Sciences. As a neuroscientist, he leads a lab interested in biological mechanisms of mental illness and investigating new therapies for mood disorders and addiction. In particular, he is defining new cell types and evolutionary conserved circuits in emotional processing centers of the brain, with the hope of finding new entry points for novel therapeutics. Working with Dr Robert Malenka, he is using optogenetic, chemogenetic, neuroimaging and behavioral approaches in mouse models of addiction to uncover vulnerable brain circuitry in opioid use disorder. Alongside Dr Alan Schatzberg, he is investigating the efficacy of buprenorphine augmentation to IV ketamine infusion at reducing suicidality in treatment resistant depression.
Clinically, he works collaboratively in the department’s Neuropsychiatry clinic and his clinical focus includes treating patients with diverse and complex presentations at the interface of psychiatry and neurology with particular interest in functional neurological disorders. He sees a small cohort of psychotherapy patients in Individual Psychotherapy Clinic. He also works weekend shifts on Stanford’s inpatient psychiatry units.
Prior to training in psychiatry at Stanford’s research residency track Jason received his bachelor’s degree in biology and philosophy from Union College. He spent three years as a Post-Baccalaureate IRTA fellow at the National Institute of Neurological Disorders and Stroke investigating and developing MRI reportable contrast agents to map neuronal connectivity. Following this he entered the Medical Scientist Training Program (MD/PhD) at the State University of NY Stony Brook University. There he completed a doctoral dissertation in neuroscience under the mentorship Dr. Josh Huang at Cold Spring Harbor Laboratory. His thesis work employed mouse genetic dissections of excitatory and inhibitory cortical circuits with a focus on the circuitry of chandelier inhibitory interneurons in prefrontal cortex.
In addition to his research and clinical work, Jason is passionate about teaching, mentorship, and resident clinical supervision. He joined a working group early in his clinical residency to restructure trainee’s neuroscience education. He teaches introductory lectures in the neuroscience of addiction, PTSD, psychosis, and mood disorders. He also leads resident group supervision in their introductory psychodynamic psychotherapy clinical experience. He supervises medical students, residents, and clinical fellows in Neuropsychiatry clinic. Finally, committed to the Stanford clinical community, he leads a support group for Internal Medicine interns and residents. -
Shripad Tuljapurkar
The Dean and Virginia Morrison Professor of Population Studies
Current Research and Scholarly InterestsStochastic dynamics of human and natural populations; prehistoric societies; probability forecasts including sex ratios, mortality, aging and fiscal balance; life history evolution.
-
Minang (Mintu) Turakhia
Clinical Professor, Medicine
Current Research and Scholarly InterestsDr. Turakhia has an active clinical research program, with funding from AHA, VA, NIH, the medical device industry, and foundations. His research program aims to improve the treatment of heart rhythm disorders, with an emphasis on atrial fibrillation, by evaluating quality and variation of care, comparative and cost-effectiveness of therapies, and risk prediction. Dr. Turakhia has extensive expertise in using large administrative and claims databases for this work. His TREAT-AF retrospective study of over 500,000 patients with newly-diagnosed AF is the largest known research cohort of AF patients. He has served as study PI or chairman of several prominent single- and multicenter trials in atrial fibrillation, investigational devices for electrophysiology procedures, digital health interventions, and sensor technologies.
His other research interests include technology assessment of new device-based therapies and the impact of changing health policy and reform on the delivery of arrhythmia care. Dr. Turakhia is a Fellow of the American Heart Association, American College of Cardiology, and Heart Rhythm Society. -
Madeleine Udell
Assistant Professor of Management Science and Engineering and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsProfessor Udell develops new techniques to accelerate and automate data science,
with a focus on large-scale optimization and on data preprocessing,
and with applications in medical informatics, engineering system design, and automated machine learning. -
Alexander Eckehart Urban
Associate Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator) and of Genetics
Current Research and Scholarly InterestsComplex behavioral and neuropsychiatric phenotypes often have a strong genetic component. This genetic component is often extremely complex and difficult to dissect. The current revolution in genome technology means that we can avail ourselves to tools that make it possible for the first time to begin understanding the complex genetic and epigenetic interactions at the basis of the human mind.