Wu Tsai Neurosciences Institute
Showing 491-500 of 507 Results
David C. Yeomans
Associate Professor of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsPhysiology of different pain types; Biomarkers of pain and inflammation; Gene Therapy for Pain
Jared and Mae Tinklenberg Professor and Professor, by courtesy, of Neurology
Current Research and Scholarly InterestsWe study cognitive processes and aging in our research center. Studies range from molecular biology to neuropsychology of cognitive processes.
Assistant Professor of Biomedical Data Science and, by courtesy, of Computer Science and of Electrical Engineering
BioDr. Serena Yeung is an Assistant Professor of Biomedical Data Science and, by courtesy, of Computer Science and of Electrical Engineering at Stanford University. Her research focus is on developing artificial intelligence and machine learning algorithms to enable new capabilities in biomedicine and healthcare. She has extensive expertise in deep learning and computer vision, and has developed computer vision algorithms for analyzing diverse types of visual data ranging from video capture of human behavior, to medical images and cell microscopy images.
Dr. Yeung leads the Medical AI and Computer Vision Lab at Stanford. She is affiliated with the Stanford Artificial Intelligence Laboratory, the Clinical Excellence Research Center, the Center for Artificial Intelligence in Medicine & Imaging, the Center for Human-Centered Artificial Intelligence, and Bio-X. She also serves on the NIH Advisory Committee to the Director Working Group on Artificial Intelligence.
Jong H. Yoon
Associate Professor of Psychiatry and Behavioral Sciences (Public Mental Health & Population Sciences)
Current Research and Scholarly InterestsMy research seeks to discover the brain mechanisms responsible for schizophrenia and to translate this knowledge into the clinic to improve how we diagnose and treat this condition. Towards these ends, our group has been developing cutting-edge neuroimaging tools to identify neurobiological abnormalities and test novel systems-level disease models of psychosis and schizophrenia directly in individuals with these conditions.
We have been particularly interested in the role of neocortical-basal ganglia circuit dysfunction. A working hypothesis is that some of the core symptoms of schizophrenia are attributable to impairments in neocortical function that results in disconnectivity with components of the basal ganglia and dysregulation of their activity. The Yoon Lab has developed new high-resolution functional magnetic resonance imaging methods to more precisely measure the function of basal ganglia components, which given their small size and location deep within the brain has been challenging. This includes ways to measure the activity of nuclei that store and control the release of dopamine throughout the brain, a neurochemical that is one of the most important factors in the production of psychosis in schizophrenia and other neuropsychiatric conditions.
Professor of Radiology (Neuroimaging and Neurointervention)
Current Research and Scholarly InterestsImproving medical image quality using deep learning artificial intelligence
Imaging of cerebral hemodynamics with MRI and CT
Noninvasive oxygenation measurement with MRI
Clinical imaging of cerebrovascular disease
Imaging of cervical artery dissection
MR/PET in Neuroradiology
Resting-state fMRI for perfusion imaging and stroke
Natalie M. Zahr
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Major Laboratories)
BioNatalie M. Zahr received a graduate education in the basic sciences including the study of neuro- pharmacology, physiology, and anatomy. After completing her graduate training in electrophysiology, she began a postdoctoral fellowship as a magnetic resonance imaging (MRI) scientist. Her work focuses on translational approaches using in vivo MR imaging and spectroscopy in studies of human alcoholics and rodent models of alcoholism with the goal of identifying fundamental mechanisms of alcohol effects on the brain. Her human studies include participants with HIV, those comorbid for HIV and alcoholism and recently, aging individuals with mild cognitive impairment. Her position allows her to explore emerging MR technologies and apply them to test relevant hypotheses. Before joining Stanford, she taught at several local institutions including UC Berkeley extension and Santa Clara University enjoying sharing her knowledge and enthusiasm for learning with her students.
Associate Professor of Psychology
Current Research and Scholarly InterestsMy research focuses on the cognitive and neural bases of social behavior, and in particular on how people respond to each other's emotions (empathy), why they conform to each other (social influence), and why they choose to help each other (prosociality).
Marguerite Blake Wilbur Professor of Natural Science and Professor, by courtesy, of Physics
Current Research and Scholarly InterestsMy research group is exploring a variety of topics that range from the basic understanding of chemical reaction dynamics to the nature of the chemical contents of single cells.
Under thermal conditions nature seems to hide the details of how elementary reactions occur through a series of averages over reagent velocity, internal energy, impact parameter, and orientation. To discover the effects of these variables on reactivity, it is necessary to carry out studies of chemical reactions far from equilibrium in which the states of the reactants are more sharply restricted and can be varied in a controlled manner. My research group is attempting to meet this tough experimental challenge through a number of laser techniques that prepare reactants in specific quantum states and probe the quantum state distributions of the resulting products. It is our belief that such state-to-state information gives the deepest insight into the forces that operate in the breaking of old bonds and the making of new ones.
Space does not permit a full description of these projects, and I earnestly invite correspondence. The following examples are representative:
The simplest of all neutral bimolecular reactions is the exchange reaction H H2 -> H2 H. We are studying this system and various isotopic cousins using a tunable UV laser pulse to photodissociate HBr (DBr) and hence create fast H (D) atoms of known translational energy in the presence of H2 and/or D2 and using a laser multiphoton ionization time-of-flight mass spectrometer to detect the nascent molecular products in a quantum-state-specific manner by means of an imaging technique. It is expected that these product state distributions will provide a key test of the adequacy of various advanced theoretical schemes for modeling this reaction.
Analytical efforts involve the use of capillary zone electrophoresis, two-step laser desorption laser multiphoton ionization mass spectrometry, cavity ring-down spectroscopy, and Hadamard transform time-of-flight mass spectrometry. We believe these methods can revolutionize trace analysis, particularly of biomolecules in cells.
Associate Professor of Radiology (Neuroimaging and Neurointervention)
BioDr. Michael Zeineh received a B.S. in Biology at Caltech in 1995 and obtained his M.D.-Ph.D. from UCLA in 2003. After internship also at UCLA, he went on to radiology residency and neuroradiology fellowship both at Stanford. He has been faculty in Stanford Neuroradiology since 2010. Combining clinical acumen in neuroradiology with advanced MRI acquisition and image processing as well as histologic validation, Dr. Zeineh hopes to advance the care of patients with neurodegenerative disorders.