School of Medicine
Showing 1-50 of 95 Results
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Raya Saab
Lindhard Family Professor of Pediatric Cancer Biology
BioOur laboratory focuses on investigating molecular mechanisms of oncogene-induced tumorigenesis and tumor suppressor pathways, and oncogenic signaling in the pediatric solid tumor rhabdomyosarcoma. Our earlier work identified the tumor suppressors p53 and p18Ink4c as inhibitors of Cyclin D1-driven tumorigenesis in a pineoblastoma model, through senescence induction, and highlighted distinct roles for the the RB and p53 pathways in induction and maintenance of oncogene-induced senescence. We also identified CDK2 as a potential target for inducing senescence in premalignant lesions to inhibit tumor progression.
Our current focus is on studying oncogenic signaling and tumor suppression in the childhood tumor rhabdomyosarcoma, to identify key mediators of invasion and metastasis, which is the most common cause of treatment failure clinically. We use preclinical in vitro and in vivo models, including murine and human cell lines, and mouse models of disease.
We have recently uncovered a paracrine role for rhabdomyosarcoma-secreted exosomes in impacting biology of stromal cells. Rhabdomyosarcoma-derived exosomes carry specific miRNA cargo that imparts an invasive and migratory phenotype on normal recipient fibroblasts, and proteomic analysis revealed specific and unique pathways relevant to the two different molecular rhabdomyosarcoma subtypes that are driven by distinct oncogenic pathways. We identified that the driver oncogene in fusion-positive rhabdomyosarcoma, PAX3-FOXO1, modulates exosome cargo to promote invasion, migration, and angiogenic properties, and identified specific microRNA and protein cargo acting as effectors of PAX3-FOXO1 exosome-mediated signaling, including modulation of oxidative stress response and cell survival signaling.
Our ongoing work is focused on interrogating specific paracrine signaling pathways and molecular mechanisms of metastatic disease progression in rhabdomyosarcoma, for potential therapeutic targeting. -
Rebecca Saenz
Clinical Assistant Professor, Pediatrics - Immunology
Current Research and Scholarly InterestsAllergy, Immunology, Bioengineering and Biodesign
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Julien Sage
Elaine and John Chambers Professor of Pediatric Cancer and Professor of Genetics
Current Research and Scholarly InterestsWe investigate the mechanisms by which normal cells become tumor cells, and we combine genetics, genomics, and proteomics approaches to investigate the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells and to identify novel therapeutic targets in cancer cells.
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Debbie C. Sakaguchi Sakai
Clinical Professor, Pediatrics
Current Research and Scholarly InterestsMedical education, shared decision making, resuscitation.
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Kathleen M. Sakamoto
Shelagh Galligan Professor in the School of Medicine
Current Research and Scholarly InterestsMy research focuses on the molecular pathways that regulate normal and aberrant blood cell development, including acute leukemia and bone marrow failure syndromes. We are also studying novel drugs for treatment of cancer.
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Christy Sandborg
Professor of Pediatrics (Rheumatology), Emerita
Current Research and Scholarly InterestsThe major emphasis of my work in the past 2 decades has been focused on the future of academic pediatrics and pediatric rheumatology through providing training, research opportunities and environments to nurture and challenge future pediatric rheumatologists and subspecialists. In parallel in the last decade, my scope has included to workforce and physician wellbring, patient and family centered care--and more recently, diversity, equity and inclusion, and health equity.
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Kelly Corbett Sanders
Clinical Instructor, Pediatrics - General Pediatrics
BioDr. Kelly Sanders is a Stanford pediatrician and the Technical Lead of the Pandemic Response Initiative at the University of California San Francisco (UCSF) Institute for Global Health Sciences. She completed a Master of Science and Doctor of Medicine at the University of San Francisco, California, and pediatrics residency training at Lucile Packard Children’s Hospital at Stanford University. Before pursuing a career as a physician, Dr. Sanders worked with the UCSF Global Health Group’s Malaria Elimination Initiative (MEI) on operational research projects with partner countries, as well as on developing communications and advocacy priorities with MEI and global partners. Previously, she worked with the UCSF Institute for Global Health Sciences, supporting the creation of the Consortium of Universities for Global Health and the UC Global Health Institute. In addition to her work at UCSF, Dr. Sanders practices clinically as a pediatrician at Stanford University, Palo Alto Medical Foundation and Santa Clara Valley Medical Center.
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Lee M. Sanders, MD, MPH
Professor of Pediatrics (General Pediatrics), of Health Policy and, by courtesy, of Epidemiology and Population Health
On Partial Leave from 01/05/2026 To 03/27/2026Current Research and Scholarly InterestsI conduct interdisciplinary research to understand literacy as potentially modifiable lens for addressing maternal and child health disparities from birth through early adulthood. Applying mixed methods approaches (health-services, epidemiology, ethnography), I have been principal investigator on extramurally-funded research projects (NIH, PCORI, FDA) that aim to examine "natural experiments" in policy and/or to design, implement and test novel system-level interventions.
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Meera N. Sankar
Clinical Professor, Pediatrics - Neonatology
Current Research and Scholarly InterestsPDA in preterm
Transcutaneous bilirubin use in the NICU
Digital health tools -
Chethan Sarabu
Clinical Assistant Professor, Pediatrics - General Pediatrics
BioChethan Sarabu, MD trained in landscape architecture, pediatrics, and clinical informatics builds anastomoses across these fields to design healthier environments and systems. He is a clinical assistant professor of Pediatrics at Stanford Medicine, Director of Clinical Informatics at Sharecare. Across these roles, he works on designing and implementing a wide array of innovations ranging from patient portals, EHR transformation, virtual clinical trials, and A.I. driven digital biomarkers, to health information policy initiatives all through a lens of health equity and patient privacy.
He takes care of patients in a community based academic general pediatrics practice at the Gardner Packard Clinic, a Federally Qualified Health Center, where he has also assisted with EHR implementation and transition. He cares deeply on involving children in their own care and strongly focused on protecting the privacy and confidentiality of adolescents in an increasingly digital healthcare system. He helped to form and co-chair the national workgroup, Shift which has been working to promote equitable interoperability.
Drawing on his background in landscape architecture, Chethan implements and researches nature based health solutions in collaboration with the Stanford Natural Capital Project. Finally, further exploring the role of environment and human health, he is shaping the emergent field of climate health informatics. -
Clea Sarnquist, DrPH, MPH
Clinical Professor, Pediatrics - Infectious Diseases
Clinical Professor (By courtesy), Epidemiology and Population HealthBioDr. Sarnquist focuses on applied teaching and research on the development, implementation and evaluation of interventions to decrease gender-based violence, improve mental health, and prevent HIV infection, especially among adolescents and children. She is particularly interested in rights-based approaches that tackle the complex interplay of factors that lead to poor health for many children and families. All of her work is applied, with direct links health practice and policy, and usually performed in conjunction with non-governmental organization and government partners. She works both globally and in the U.S., with a focus on sub-Saharan Africa. She is also a medical educator, directing the scholarly concentrations program of the pediatric residency at Stanford, co-directing the global health concentration for residents, and teaching graduate and undergraduate courses in global health with a focus on children and women’s health.
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Andrew Saunders
Clinical Associate Professor, Pediatrics
BioDr. Saunders (he/him) is a Clinical Associate Professor of Pediatrics, and the medical director of the Pediatric Hospitalist Program at SHC Tri-Valley. His academic interests include diversity, equity, and inclusion in medicine; LGBTQIA+ health; ethics in technology; global health; medical education; public health; and physician wellness.
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Nazish Sayed MD, PhD
Associate Professor (Research) of Surgery (Vascular Surgery)
Current Research and Scholarly InterestsThe Sayed Laboratory is focused on the development of novel technologies that drive innovation in regenerative medicine, disease modeling, and drug testing in vascular biology. The lab conducts translational research in vascular biology and aims to understand the role of the vasculature in the development of cardiac diseases, including those due to inherited genetic variants or environmental insults such as type 2 diabetes or hypertension. The lab employs the human induced pluripotent stem cell (iPSC) technology to generate patient-specific vascular cells (endothelial and vascular smooth muscle cells) as an alternative to animal models providing a human tissue surrogate for research that is scalable and sustainable. By employing this unique platform, the lab also investigates the role of chemotherapeutic agents (anti-cancer drugs) on the vasculature. Dr. Sayed’s lab has also established an endothelial regeneration program, where they leverage the innate immune system to regenerate endothelial cells from human fibroblasts.
Work from the lab has led to seminal discoveries in the areas of 1) Nitric oxide (NO) biology, (2) vascular biology, (3) stem cell biology, (4) cardiovascular disease modeling (5) cardio-oncology. -
Michael Scahill
Clinical Assistant Professor, Pediatrics - Neonatology
BioOn a trip to Mozambique while in med school here at Stanford, Dr Scahill saw the power of market interventions to transform healthcare. This led to his current focus on technology, data & AI. A veteran data scientist, his research trawls the oceans of data each patient generates for patterns to predict dangerous outcomes before they happen in Stanford's top level NICU, where he also still serves as a frontline clinician. Outside Stanford, he is the digital lead at Valley Children's hospital and advises health technology startups in Silicon Valley and beyond.
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David Scheinker
Clinical Professor, Pediatrics - Endocrinology
Clinical Professor, MedicineBioDavid Scheinker is the Executive Director of Systems Design and Collaborative Research at the Stanford Lucile Packard Children's Hospital. He is the Founder and Director of SURF Stanford Medicine, a group that brings together students and faculty from the university with physicians, nurses, and administrators from the hospitals. SURF has implemented and published dozens of projects demonstrating improvements to the quality and efficiency of care. His areas of focus include clinical care delivery, technical improvements to hospital operations, sensor-based and algorithm-enabled telemedicine, and the socioeconomic factors that shape healthcare cost and quality.
Before coming to Stanford, he was a Joint Research Fellow at The MIT Sloan School of Management and Massachusetts General Hospital. He received a PhD in theoretical math from The University of California San Diego under Jim Agler. He advises Carta Healthcare, a healthcare analytics company started by former students. -
Alan Schroeder
Clinical Professor, Pediatrics
BioDr. Schroeder is the associate chief for research in the division of pediatric hospital medicine at Lucile Packard Children’s Hospital Stanford, and a clinical professor in the division of hospital medicine and the division of critical care. His research interests focus on identifying areas where we can “safely do less” in healthcare, striving to ensure that children get the healthcare that they need while avoiding excessive tests and treatments that only cause harm. Dr. Schroeder is currently involved in multiple projects involving common conditions and interventions in pediatrics. He serves as the Stanford PI for PEDSNet and is an Associate Editor for the journal Hospital Pediatrics. At Stanford he co-leads the residency clinical research scholarly concentration and the faculty Clinical Research Peer Scholarship Community. Dr. Schroeder provides clinical care for children in the PICU and the pediatric ward.
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Christopher Thomas Scott, PhD, MLA
Sr Research Scholar, Pediatrics - Center for Biomedical Ethics
Current Research and Scholarly InterestsMy research focuses on the political, legal, ethical and economic impacts of stem cell research. Topics include: embryonic and adult stem cell research and clinical trials, stem cell banking, human-animal chimeras; cell and gamete donation; international perspectives of bioethics; global economic impacts; national and state regulatory policy, stem cell entrepreneurship, intellectual property and offshore stem cell transplants.
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Jennifer Andrene Sequoia
Instructor, Pediatrics - Neonatology
BioJennifer Sequoia, MD, PhD is an Instructor in Neonatology at Stanford University. She completed her Neonatology Fellowship and Pediatrics Residency (Research Track) at Stanford. Prior to coming to Stanford she received her undergraduate and master's degrees from University of California, San Diego and her MD and PhD degrees from The University of Chicago. As faculty at Stanford, she is developing a research program to understand how endogenous cannabinoids impact preeclampsia and other perinatal diseases. She is broadly interested in how lipids mediate inflammatory programs and is working to develop new molecular tools to study lipids in their native environments.
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Ami J. Shah
Clinical Professor, Pediatrics - Stem Cell Transplantation
BioDr. Shah joined Stanford University in 2015 as a Clinical Professor of Pediatrics in the Division of Hematology/ Oncology, Stem Cell Transplantation and Regenerative Medicine. Dr. Shah completed medical school at the University of North Carolina- Chapel Hill. She completed her training in Pediatrics and Pediatric Hematology/ Oncology at Childrens Hospital Los Angeles. Her areas of clinical expertise have been in stem cell transplantation for malignant and non-malignant disorders. She has been actively involved with the care and treatment of children with primary immune deficiencies and is the site PI for the Primary Immune Deficiencies Consortium (PIDTC). She has experience in numerous gene therapy trials for primary immune deficiencies, hemoglobinopathies and other genetic diseases. She has a specific interest in the long term outcomes following HSCT, in specific the neurocognitive function post HSCT. She has been an active participant in American Society of Transplantation and Cellular Therapy (ASTCT), Children's Oncology Group (COG) and American Society of Hematology (ASH).
She has been actively involved with mentorship and graduate medical education, and currently serves as the Program Director for the Pediatric Hematology/ Oncology Fellowship and the Pediatric Stem Cell Fellowship. She also serves on the Pediatric Mentoring Group. -
Manish I. Shah, MD, MS
Professor of Emergency Medicine (Pediatrics) and, by courtesy, of Pediatrics (Hospital Medicine)
BioI have dedicated my career to improving pediatric prehospital care on local, statewide, national, and international levels through research, education, and advocacy. My primary research interest focuses on integration of pediatric evidence into emergency medical services (EMS) systems. I serve on the Executive Committee of the Pediatric Emergency Care Applied Research Network (PECARN) as the nodal Principal Investigator (PI) for the Charlotte, Houston, and Milwaukee Prehospital (CHaMP) research node. In addition, I am the PI for the Pediatric Dose Optimization for Seizures in EMS (PediDOSE) clinical trial and co-investigator for the Pediatric Prehospital Airway Resuscitation Trial (Pedi-PART). As an educational researcher, I have obtained several grants to produce an online EMS educational resource for physicians, create the Pediatric Simulation Training of Emergency Prehospital Providers (PediSTEPPs) program, and study the implementation of an EMS training curriculum for the Botswana Ministry of Health. As an EMS advocate, I led the Prehospital and State Partnership domains for the national EMS for Children (EMSC) Innovation and Improvement Center (EIIC), served as an appointed member of the National Emergency Medical Services Advisory Council (NEMSAC), chaired the EMS subcommittee for the American Academy of Pediatrics Section of Emergency Medicine, and directed the EMSC State Partnership in Texas. I have published policy on pediatric readiness in EMS systems and co-chaired the workgroup that created the first-ever national assessment of pediatric readiness of EMS systems for the National Prehospital Pediatric Readiness Project (PPRP).
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Mona D. Shah, MD, MBA
Adjunct Clinical Associate Professor, Pediatrics - Hematology & Oncology
BioDr. Mona Shah is a pediatric hematologist-oncologist, who earned her MD degree at the University of Maryland in 2001. She completed both her categorical pediatrics and global health residencies in 2004, followed by a pediatric hematology-oncology fellowship in 2007. She earned her MS in Clinical Investigation as part of the Clinical Scientist Training Program (CSTP) at Baylor College of Medicine in 2011, and more recently, completed an Executive MBA at Rice University Jones School of Business in 2018.
Dr. Shah was an Associate Professor at Baylor College of Medicine (2007 - 2020) in both Pediatrics and Medicine, local site PI on a number of pediatric hemostasis/thrombosis clinical trials, and spent 10 years as an Associate Medical Director of Clinical Operations, Quality, and Safety at Texas Children’s Hospital, Houston, TX.
Dr. Shah joined Genentech (a Member of the Roche Group)’s Rare Blood Disorders Franchise (Product Development - Oncology-Hematology) in February 2020, quickly advancing to Lead Medical Director, where she served as Medical Monitor for 2 Phase III Clinical Trials (crovalimab in atypical hemolytic uremic syndrome, aHUS). She was also engaged with the Renal Franchise (I2O) in developing crovalimab in Lupus Nephritis (Phase I & II Clinical Trials in development), and with Human Factors/Pediatric Formulations Working Group on autoinjector devices and oral formulations.
After completing a rotation in Early Development Safety (EDS), she was promoted to Senior Medical Safety Director in Late Stage Product Development, and was appointed Safety Strategy Lead for giredestrant in early and metastatic breast, ovarian, and endometrial cancer global clinical trials. She has experience in innovative study designs (adaptive/multi-drug), with FDA/EMA pediatric investigational plans, and health authority interactions. In June 2023, she was appointed Pediatric Safety Lead, in collaboration with the iPODD Team, supporting safety for pediatric indications and devices, and serves as the Co-Chair of the Pediatric Safety Expert Group.
Dr. Shah has kept and completed a bucket list since she was 7 years old (keeps growing): Running wild bouldering/rock climbing as a child in the Shenandoah/Blue Ridge Mountains, swimming with dolphins/piranhas in the Amazon, climbing inside a volcano caldera in Iceland, snorkeling the Great Barrier Reef ... have passport/will travel!
Since July 2022, she has joined Stanford University School of Medicine, as an Adjunct Clinical Associate Professor in the Department of Pediatrics, Division of Hematology-Oncology, where she enjoys teaching MSII students, and at the bedside in the Lucille Packard Bass Center Hematology Clinic. Dr. Shah enjoys free time in her new home base near San Francisco, where she hosts her visiting parents, friends, and extended family. -
Sejal Shah
Clinical Associate Professor, Pediatrics - Endocrinology
Current Research and Scholarly InterestsMy primary research interest is evaluating whether vitamin D supplementation can positively affect consequences of the metabolic syndrome in overweight and obese adolescents. Other research interests include evaluating the efficacy and biochemical profiles of various types of estrogen replacement in adolescent females.
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Paul Sharek MD, MPH
Professor of Pediatrics (Hospital Medicine) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsResearch interests centered on hospital based quality of care improvement, and in particular pediatric patient safety. Areas of recent interest include developing practical tools to more accurately identify adverse medical events and to establish national rates of these adverse events. Additional areas of interest focus on developing the processes and systems to decrease the frequency of adverse drug events and adverse medical events at Children's hospitals in North America
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Gary M. Shaw
Rosemarie Hess Professor and Professor (Research), by courtesy, of Epidemiology and Population Health and of Obstetrics and Gynecology (Maternal Fetal Medicine)
Current Research and Scholarly InterestsPrimary research interests include 1) epidemiology of birth defects, 2) gene-environment approaches to perinatal outcomes, and 3) nutrition and reproductive outcomes.
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Xinshu She
Clinical Associate Professor, Pediatrics
Current Research and Scholarly InterestsMy current interests include global mental health promotion in underserved pediatric populations, including refugee health in US-Mexico borders, minority mental health in the US, and parental mental health in low-middle-income countries. I am also interested in physician wellness and Diversity and Inclusion.
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Hiroyuki Shimada
Professor of Pathology and, by courtesy, of Pediatrics
BioHiroyuki Shimada, MD, PhD, FRCPA (Hon), is Professor of Pathology and of Pediatrics at the Stanford University Medical Center. He was born in Tokyo, Japan, and completed MD (1973) and PhD (1982) at the Yokohama City University School of Medicine, Yokohama, Japan, and also completed his pathology training at the Children's Hospital (now the Nationwide Children’s Hospital) and the Ohio State University, Columbus, Ohio, USA (1988). Before moving to the Stanford University in 2019, he was Professor of Pathology (Clinical Scholar) at the University of Southern California Keck School of Medicine and working at the Children’s Hospital Los Angeles.
Dr. Shimada was Chair of the International Neuroblastoma Pathology Committee (1999-2017) and the founder of the International Neuroblastoma Pathology Classification (INPC). As Director of the COG (Children’s Oncology Group) Neuroblastoma Pathology Reference Laboratory (since 2001), he has been actively reviewing pathology samples of ~700 neuroblastoma cases per year from United States, Canada, Australia, and New Zealand. Pathology review results according to the INPC have been providing critical information for patient stratification and protocol assignment in the COG international neuroblastoma clinical trials. -
Andrew Young Shin
Clinical Professor, Pediatrics - Cardiology
Current Research and Scholarly InterestsSURF PROGRAM
The SURF program is an innovative collaboration between LPCH, Stanford University Hospital and the Stanford School of Engineering. The program has focused on improving quality and safety of patient care, improving hospital operations and promoting clinical effectiveness utilizing contemporary technologies such as machine learning, mathematical optimization, simulation and a variety of statistical, probabilistic and computational tools. The program has 2 independent funding mechanism to primarily improve patient care/hospital operations and improve academics for faculty within the department of Pediatrics at LPCH.
https://surf.stanford.edu/
CLINICAL EFFECTIVENESS
The Clinical Effectiveness (CE) Program is a funded program that aims to understand and improve unnecessary variation in healthcare delivery in order to optimize quality of care and reduce wasteful expenditures. The CE program has developed innovative programs such as Target Based Care, an award-winning intervention to reduce variation in hospital length of stay and currently a multi-center trial involving more than 20 hospitals in North America. In 2016, the CE program included the first CE fellowship program in a pediatric training program with 3 cycles of graduates. The CE program is supported by LPCH and a philanthropic gift by Susan Choe and Thomas Tobiason. -
Ann Shue, MD
Clinical Assistant Professor, Ophthalmology
Clinical Assistant Professor (By courtesy), PediatricsBio**Dr. Shue is taking new patients for glaucoma, cataracts, and adult strabismus.**
Ann Shue, MD, is a Clinical Assistant Professor of Ophthalmology at Stanford University School of Medicine, where she specializes in glaucoma, pediatric ophthalmology, and adult strabismus, a unique combination of subspecializations practiced by few surgeons worldwide. She is a board-certified ophthalmologist who completed fellowships in glaucoma at Yale University and pediatric ophthalmology and adult strabismus at Duke University. She practices at the Stanford Byers Eye Institute and the Lucile Packard Children's Hospital.
Dr. Shue loves seeing patients of all ages with eye problems big or small, including glaucoma due to any reason, glaucoma suspicion, family history of glaucoma, cataracts, strabismus (eye misalignment) or double vision from any cause, including after eye surgeries. She completed her ophthalmology residency at the University of Pittsburgh and an internal medicine internship at UCSF Fresno. She holds a medical degree from University of California, Irvine and an undergraduate degree in biology from Yale University.
Dr. Shue is a member of the American Glaucoma Society, the American Association for Pediatric Ophthalmology and Strabismus, and the UK Paediatric Glaucoma Society. She is active in presenting at regional and national conferences. She is the author of several journal articles and recently wrote two textbook chapters on pediatric glaucoma and pediatric glaucoma surgery.
