School of Medicine
Showing 10,151-10,160 of 10,162 Results
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J. Bradley Zuchero
Assistant Professor of Neurosurgery
Current Research and Scholarly InterestsGlia are a frontier of neuroscience, and overwhelming evidence from the last decade shows that they are essential regulators of all aspects of the nervous system. The Zuchero Lab aims to uncover how glial cells regulate neural development and how their dysfunction contributes to diseases like multiple sclerosis (MS) and in injuries like stroke.
Although glia represent more than half of the cells in the human brain, fundamental questions remain to be answered. How do glia develop their highly specialized morphologies and interact with neurons to powerfully control form and function of the nervous system? How is this disrupted in neurodegenerative diseases and after injury? By bringing cutting-edge cell biology techniques to the study of glia, we aim to uncover how glia help sculpt and regulate the nervous system and test their potential as novel, untapped therapeutic targets for disease and injury.
We are particularly interested in myelin, the insulating sheath around neuronal axons that is lost in diseases like MS. How do oligodendrocytes- the glial cell that produces myelin in the central nervous system- form and remodel myelin, and why do they fail to regenerate myelin in disease? Our current projects aim to use cell biology and neuroscience approaches to answer these fundamental questions. Ultimately we hope our work will lead to much-needed therapies to promote remyelination in patients. -
Evan Zucker
Clinical Associate Professor, Radiology - Pediatric Radiology
BioDr. Zucker is a board-certified pediatric and cardiovascular radiologist with a special interest in CT and MRI for congenital heart disease.
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Donna Zulman
Assistant Professor of Medicine (General Medical Disciplines)
Current Research and Scholarly Interests- Improving care and supporting self-management for patients with multiple chronic conditions
- Designing and evaluating innovative health care delivery models for complex and costly patients
- Optimizing health-related technology to personalize and improve care for complex patients and their caregivers
