Wu Tsai Neurosciences Institute
Showing 51-100 of 661 Results
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Anna Maria Bombardieri, MD, PhD, MSc
Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsMy overall research goal is to advance clinical practice by providing anesthesiologists with data to most effectively maintain cerebral blood flow in the perioperative period.
I am interested in the effect of the autonomic nervous system on cerebral blood flow regulation.
I intend to combine regional anesthetic techniques and noninvasive bedside cerebral blood flow monitoring to understand the effect of the sympathetic system on cerebral blood flow.
A secondary goal is to apply this new knowledge to investigate whether cervical sympathetic blocks improve long term neurological outcomes. -
Daniel L. Bowling, PhD
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Sciences)
BioDr. Bowling is Director of the Music, Brain & Health Lab at Stanford School of Medicine. His translational research harnesses the neural effects of music to develop personalized music-based treatments for health and wellness, with a particular focus on anxiety and depression in young adults. His approach integrates expertise in neuroscience, bioacoustics, music therapy, and psychiatry to apply insights from music's underlying biology to medicine.
Dr. Bowling earned his PhD in Neurobiology from Duke University School of Medicine and holds graduate certificates in Cognitive Neuroscience and Translational Medicine. He has authored over 40 peer-reviewed publications in leading journals including Science, PNAS, and Molecular Psychiatry. His research program has been supported by federal and private foundations including the National Institutes of Health, NeuroArts Blueprint, and the American Foundation for Suicide Prevention. -
Steven Boxer
Camille Dreyfus Professor of Chemistry
Current Research and Scholarly InterestsPlease visit my website for complete information:
http://www.stanford.edu/group/boxer/ -
Mark Brongersma
Director, Geballe Laboratory for Advanced Materials (GLAM), Stephen Harris Professor, Professor of Materials Science and Engineering and, by courtesy, of Applied Physics
BioMark Brongersma is a Professor in the Department of Materials Science and Engineering at Stanford University. He received his PhD in Materials Science from the FOM Institute in Amsterdam, The Netherlands, in 1998. From 1998-2001 he was a postdoctoral research fellow at the California Institute of Technology. During this time, he coined the term “Plasmonics” for a new device technology that exploits the unique optical properties of nanoscale metallic structures to route and manipulate light at the nanoscale. His current research is directed towards the development and physical analysis of nanostructured materials that find application in nanoscale electronic and photonic devices. Brongersma received a National Science Foundation Career Award, the Walter J. Gores Award for Excellence in Teaching, the International Raymond and Beverly Sackler Prize in the Physical Sciences (Physics) for his work on plasmonics, and is a Fellow of the Optical Society of America, the SPIE, and the American Physical Society.
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Helen Bronte-Stewart, MD, MS
John E. Cahill Family Professor, Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy research focus is human motor control and brain pathophysiology in movement disorders. Our overall goal is to understand the role of the basal ganglia electrical activity in the pathogenesis of movement disorders. We have developed novel computerized technology to measure fine, limb and postural movement. With these we are measuring local field potentials in basal ganglia nuclei in patients with Parkinson's disease and dystonian and correlating brain signalling with motor behavior.
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Anne Brunet
Michele and Timothy Barakett Endowed Professor
Current Research and Scholarly InterestsWe want to understand aging based on the integration of model organisms with diverse lifespans. We have identified pathways involved in delaying aging in response to external stimuli such as availability of nutrients. We are also interested in addressing complex questions about aging in vertebrates, focusing on brain aging and rejuvenation. Finally, we have pioneered the short-lived African killifish as a powerful model to identify new principles of vertebrate aging and ‘suspended animation’.
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Axel Brunger
Professor of Molecular and Cellular Physiology, of Neurology and Neurological Sciences, of Photon Science and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsOne of my primary goals is to elucidate the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, in conjunction with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.
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Jennifer L. Bruno
Instructor, Psychiatry and Behavioral Sciences - Interdisciplinary Brain Sciences
Current Research and Scholarly InterestsDr. Bruno is a translational researcher at the interface of developmental cognitive neuropsychology and neurobiology. An overarching goal of her work is to understand developmental windows of vulnerability—periods of risk for falling off the trajectory of typical brain development. Her research utilizes genetics, brain imaging, and deep behavioral phenotyping to bridge computational science with clinical knowledge, translating cutting-edge science to solve problems of great clinical need.
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Zev Bryant
Associate Professor of Bioengineering and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsMolecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work.
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Vivek P. Buch, MD
Assistant Professor of Neurosurgery and, by courtesy, of Bioengineering
BioDr. Buch is a neurosurgeon with fellowship training in epilepsy, functional, and minimally invasive neurosurgery. He is an Assistant Professor of Neurosurgery, and Christina and Hamid Moghadam Faculty Scholar at Stanford University.
Dr. Buch focuses his expertise on the open and minimally invasive treatment of epilepsy, low grade brain tumors, movement and neuropsychiatric disorders, facial and body pain syndromes, and other complex neurological conditions. He uses advanced and innovative techniques to treat both adult and pediatric patients. For each patient, he develops a personalized care plan that is designed to be both comprehensive and compassionate.
Dr. Buch has conducted extensive research. His career goal is to develop restorative bioengineering approaches for complex neurocognitive, neurodevelopmental, and neuropsychiatric disorders. He is creating network-neuroprosthetics and precision molecular therapies to restore abnormal brain circuit function in these vulnerable patient populations. He is further pioneering novel intraoperative technologies including personalized network-based targeting, holographic mixed reality, and artificial intelligence platforms for minimally invasive cranial surgery.
He has co-authored articles on his research discoveries in Science, Nature, Nature Medicine, Neuron, Brain, Annals of Surgery, Frontiers in Neuroscience, Epilepsia, Brain Stimulation, Stereotactic and Functional Neurosurgery, Surgical Innovation, Frontiers in Surgery, Journal of Neurosurgery, and many other journals. Articles focus on developing novel network control theory applications to human brain functions and new techniques and technologies to enhance neurosurgical effectiveness and patient outcomes.
He is the Section Editor for NEUROSURGERY, and a guest editor for Surgical Innovation and Brain Sciences. He also has co-authored chapters in the books Neurosurgical Atlas, Operative Techniques in Epilepsy Surgery, Deep Brain Stimulation, and The Encyclopedia of Medical Robotics.
Dr. Buch has presented the findings of his research at the national conferences of numerous professional associations. Among them are the American Association of Neurological Surgeons, Society for Neuroscience, Congress of Neurological Surgeons, and Society for Imaging Informatics in Medicine. Topics include understanding network mechanisms of cognitive control and advances in the use of augmented reality technology to enhance neurosurgical approaches.
For his clinical, research, and academic achievements. Dr. Buch has earned many honors. He has won awards from the American Association of Neurological Surgeons, American Roentgen Ray Society, Congress of Neurological Surgeons, and National Institutes of Health.
Dr. Buch is a member of the American Association of Neurological Surgeons, Congress of Neurological Surgeons, World Society for Stereotactic and Functional Neurosurgery, American Association of Stereotactic and Functional Neurosurgery, and Alpha Omega Alpha Medical Honor Society.
He holds patents on such topics as artificial intelligence systems designed to help guide surgery and neural control signals for behavioral modification and closed-loop stimulation therapy.
Essential tremor patient story: https://www.youtube.com/watch?v=fV6BzyU9b3c
Parkinson's disease patient story: https://www.youtube.com/watch?v=vAKP7SRKs08
Epilepsy patient story: https://www.youtube.com/watch?v=HXy-gXg0t94&t=3s
Deep brain stimulation treatment: https://www.youtube.com/watch?v=xLgEcb447gA&t=1s
Laser interstitial thermal therapy treatment: https://www.youtube.com/watch?v=z-nRUMbs2kY&t=2s
MR-guided focused ultrasound treatment: https://www.youtube.com/watch?v=3Bwq2YxD9eU -
Paul Buckmaster, DVM, PhD
Professor of Comparative Medicine and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsMechanisms of epilepsy, especially temporal lobe epilepsy.
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Marion S. Buckwalter, MD, PhD
Professor of Neurology and Neurological Sciences (Adult Neurology) and of Neurosurgery
Current Research and Scholarly InterestsThe goal of the Buckwalter Lab is to improve how people recover after a stroke. We use basic and clinical research to understand the cells, proteins, and genes that lead to successful recovery of function, and also how complications develop that impact quality of life after stroke. Ongoing projects are focused on understanding how inflammatory responses are regulated after a stroke and how they affect short-term brain injury and long term outcomes like dementia and depression.
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Marshall Burke
Professor of Environmental Social Sciences, Senior Fellow at the Freeman Spogli Institute for International Studies, at the Woods Institute for the Environment, at SIEPR and Professor, by courtesy, of Earth System Science
BioMarshall Burke is professor of Global Environmental Policy in the Doerr School of Sustainability at Stanford, a senior fellow at the Center on Food Security and the Environment, the Freeman Spogli Institute for International Studies, the Stanford Woods Institute for the Environment, and Stanford Institute for Economic Policy Research, all at Stanford. He is also a research fellow at the National Bureau of Economic Research. His research uses tools from the social and natural sciences to measure environmental change, how society is impacted by this change, and how it can respond. He holds a PhD in Agricultural and Resource Economics from UC Berkeley, and a BA in International Relations from Stanford. He directs the Environmental Change and Human Outcomes Lab at Stanford, is co-founder of AtlasAI, and co-creator of the Environmental Hazards Adaptation Atlas.
Prospective students should see my personal and lab webpages, linked at right. -
Eugene Butcher
Klaus Bensch Professor of Pathology
Current Research and Scholarly InterestsOur interests include:
-Lymphocyte migration and vascular specialization in immunity and inflammation;
-Single-cell and multi-omics dissection of vascular and immune system heterogeneity;
-AI-driven deorphanization of GPCRs and ligand discovery
-Reprogramming of vascular and immune niches in immunity and tolerance;
-Systems biology of immune cell targeting in health and disease -
Weidong Cai
Clinical Associate Professor, Psychiatry and Behavioral Sciences
BioMy research program investigates the neurobiological basis of cognitive dysfunction across the lifespan, focusing on two critical populations: children with neurodevelopmental disorders (e.g., ADHD) and elders with neurodegenerative conditions (e.g., Parkinson’s disease). By employing a highly interdisciplinary approach that integrates cognitive science, advanced functional neuroimaging, and computational modeling, I aim to delineate the neurocognitive processes governing both typical and atypical brain development and aging. The ultimate goal is to advance our understanding of the factors contributing to cognitive deficits and translate these findings into improved diagnostic tools and precision treatment strategies.
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David Camarillo
Associate Professor of Bioengineering and, by courtesy, of Neurosurgery and of Mechanical Engineering
BioDavid B. Camarillo is Associate Professor of Bioengineering, (by courtesy) Mechanical Engineering and Neurosurgery at Stanford University. Dr. Camarillo holds a B.S.E in Mechanical and Aerospace Engineering from Princeton University, a Ph.D. in Mechanical Engineering from Stanford University and completed postdoctoral fellowships in Biophysics at the UCSF and Biodesign Innovation at Stanford. Dr. Camarillo worked in the surgical robotics industry at Intuitive Surgical and Hansen Medical, before launching his laboratory at Stanford in 2012. His current research focuses on precision human measurement for multiple clinical and physiological areas including the brain, heart, lungs, and reproductive system. Dr. Camarillo has been awarded the Hellman Fellowship, the Office of Naval Research Young Investigator Program award, among other honors including multiple best paper awards in brain injury and robotic surgery. His research has been funded by the NIH, NSF, DoD, as well as corporations and private philanthropy. His lab’s research has been featured on NPR, the New York Times, The Washington Post, Science News, ESPN, and TED.com as well as other media outlets aimed at education of the public.
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Jan Carette
Professor of Microbiology and Immunology
Current Research and Scholarly InterestsOur research focuses on the identification of host genes that play critical roles in the pathogenesis of infectious agents including viruses. We use CRISPR genetic screens in human cells as an efficient approach to perform loss-of-function studies. Besides obtaining fundamental insights on how viruses hijack cellular processes and on host defense mechanisms, it may also facilitate the development of new therapeutic strategies.
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Victor G. Carrión
John A. Turner Endowed Professor for Child and Adolescent Psychiatry
Current Research and Scholarly InterestsExamines the interplay between brain development and stress vulnerability via a multi-method approach that includes psychophysiology, neuroimaging, neuroendocrinology and phenomenology. Treatment development that focuses on individual and community-based interventions for stress related conditions in children and adolescents that experience traumatic stress.
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Ian Carroll, MD, MS
Associate Professor of Anesthesiology, Perioperative and Pain Medicine (Adult Pain)
Current Research and Scholarly InterestsWe are committed to promoting an understanding of cerebrospinal fluid (CSF) leaks, and ensuring that all patients who are suffering from cerebrospinal fluid leaks receive appropriate diagnosis and treatment of this devastating, chronic, and fixable condition. We believe this can be best accomplished in a multidisciplinary setting involving expertise in radiology, neurology, and interventional pain medicine.
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Laura L. Carstensen
Director, Stanford Center on Longevity, Fairleigh S. Dickinson, Jr. Professor of Public Policy and Professor, by courtesy, of Health Policy
BioLaura L. Carstensen is Professor of Psychology at Stanford University where she is the Fairleigh S. Dickinson Jr. Professor in Public Policy and founding director of the Stanford Center on Longevity. Her research on the theoretical and empirical study of motivational, cognitive, and emotional aspects of aging has been funded continuously by the National Institute on Aging for more than 30 years. Carstensen is an elected member of the National Academy of Medicine and the American Academy of Arts and Sciences. She served on the MacArthur Foundation’s Research Network on an Aging Society and was a commissioner on the Global Roadmap for Healthy Longevity. Carstensen’s awards include a Guggenheim Fellowship, the Kleemeier Award, The Richard Kalish Award for Innovative Research and distinguished mentor awards from both the Gerontological Society of America and the American Psychological Association. She is the author of A Long Bright Future: Happiness, Health, and Financial Security in an Age of Increased Longevity. Carstensen received her B.S. from the University of Rochester and her Ph.D. in Clinical Psychology from West Virginia University. She holds honorary doctorates from Katholieke Universiteit Leuven and the University of Rochester.
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Lynette Cegelski
Monroe E. Spaght Professor of Chemistry and Professor, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsResearch in the Cegelski laboratory is driven by the need to uncover and define the chemistry that underlies outstanding challenges in human health, the environment, and sustainability. Beyond discovery, we use chemistry as a tool to innovate and create solutions to these pressing problems. The laboratory is highly interdisciplinary, designing experimental approaches to understand how complex biological systems are built, organized, and controlled, and then perturb and influence assembly processes. The lab develops new methods and uniquely leverages: (1) small molecules in new biochemical assay development, chemical genetics approaches, and therapeutic discovery in infectious diseases, (2) fluorescence and electron microscopy coupled to analytical HPLC, mass spectrometry, and complementary biochemical techniques, and (3) spectroscopy, particularly solid-state NMR, to uncover new “dark matter” and define chemistry in insoluble, heterogeneous and complex assemblies relevant to human health, plants, and the ocean.
Long-standing efforts in the laboratory focus on defining mechanisms underlying bacterial biofilm formation and identifying new antibiotic and anti-virulence strategies, including advancing therapeutic candidates for the most difficult-to-treat infections. Through these efforts, we uncovered a new chemical structure in nature: phosphoethanolamine (pEtN) cellulose. Cellulose is the most abundant biopolymer on earth and this discovery provided the first experimental validation of a naturally produced chemically modified cellulose. We are developing alternatively modified celluloses and polysaccharides and advancing new solutions for ecofriendly, sustainably sourced, and recyclable materials. Collectively, our projects span disciplines from molecular structure and assembly chemistry to living microbial communities and natural marine systems, while aiming to translate fundamental discoveries into therapeutic and materials solutions. -
Chris Chafe
Duca Family Professor
BioChris Chafe is a composer, improvisor, and cellist, developing much of his music alongside computer-based research. He is Director of Stanford University's Center for Computer Research in Music and Acoustics (CCRMA). In 2019, he was International Visiting Research Scholar at the Peter Wall Institute for Advanced Studies The University of British Columbia, Visiting Professor at the Politecnico di Torino, and Edgard-Varèse Guest Professor at the Technical University of Berlin. At IRCAM (Paris) and The Banff Centre (Alberta), he has pursued methods for digital synthesis, music performance and real-time internet collaboration. CCRMA's jacktrip project involves live concertizing with musicians the world over. Online collaboration software and research into latency factors continue to evolve. An active performer either on the net or physically present, his music reaches audiences in sometimes novel venues. An early network project was a simultaneous five-country concert was hosted at the United Nations in 2009. Chafe’s works include gallery and museum music installations which are now into their second decade with “musifications” resulting from collaborations with artists, scientists and MD’s. Recent work includes the Earth Symphony, the Brain Stethoscope project (Gnosisong), PolarTide for the 2013 Venice Biennale, Tomato Quintet for the transLife:media Festival at the National Art Museum of China and Sun Shot played by the horns of large ships in the port of St. Johns, Newfoundland.
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Kevin Chuen Wing Chan
Associate Professor of Ophthalmology (Research/Clinical Trials)
Current Research and Scholarly Interests(1) MR ocular imaging and neuroimaging of degeneration, development, protection, plasticity, and regeneration in humans and experimental animal models.
(2) Structural, metabolic, physiological, and functional relationships between eye, brain, and behavior in health and disease. -
Pak H. Chan
The James R. Doty Professor in Neurosurgery and Neurosciences, Emeritus
Current Research and Scholarly InterestsNeuronal death and regeneration after strokeand neural injury
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Howard Y. Chang, MD, PhD
Virginia and D. K. Ludwig Professor of Cancer Research, Professor of Genetics and, by courtesy, of Pathology
On Leave from 12/16/2024 To 12/15/2026Current Research and Scholarly InterestsOur research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.
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Kay W. Chang, MD
Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics
Current Research and Scholarly Interestshttp://med.stanford.edu/ohns/research/labs_chang.html
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Steven D. Chang, MD
Robert C. and Jeannette Powell Neurosciences Professor and, by courtesy, of Otolaryngology - Head & Neck Surgery (OHNS) and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsClinical research includes studies in the treatment of cerebrovascular disorders, such as aneurysms and AVMs, as well as the use of radiosurgery to treat tumors and vascular malformations of the brain and spine.
Dr. Chang is C0-Director of the Cyberknife Radiosurgery Program.
Dr. Chang is also the head of the The Stanford Neuromolecular Innovation Program with the goal of developing new technologies to improve the diagnosis and treatment of patients affected by neurological conditions. -
Akshay Chaudhari
Associate Professor (Research) of Radiology (Integrative Biomedical Imaging Informatics at Stanford) and of Biomedical Data Science
Current Research and Scholarly InterestsDr. Chaudhari is interested in the application of artificial intelligence techniques to all aspects of medical imaging, including automated schedule and reading prioritization, image reconstruction, quantitative analysis, and prediction of patient outcomes. His interests focus on the development and evaluation new self-supervised and representation learning techniques for multi-modal deep learning in healthcare using vision, language, and medical records data
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Can Chen
Clinical Assistant Professor, Medicine - Primary Care and Population Health
BioDr. Can Chen is a board-certified physician specializing in internal medicine and geriatric medicine, with a clinical focus on post-acute and long-term care. She is a Certified Medical Director by PALTmed (Post-Acute and Long-Term Care Medical Association) and serves as the Medical Director for The Sequoias Portola Valley Continuing Care Residential Community, where she is committed to enhancing the quality of care for senior residents.
Dr. Chen excels in shared decision-making and creating individualized care plans, emphasizing personalized approaches to advance care planning, dementia care, and beyond. Her dedication to improving quality standards in geriatric care extends to her involvement in quality improvement initiatives, interdisciplinary team education, and community education in senior living environments. Dr. Chen actively engages in guiding seniors and their families through the complexities of healthcare and aging, advocating for informed and compassionate care. -
James K. Chen
Jauch Professor and Professor of Chemical and Systems Biology, of Developmental Biology and of Chemistry
Current Research and Scholarly InterestsOur laboratory combines chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.
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Lu Chen
Professor of Neurosurgery and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsWhat distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation.
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Xiaoke Chen
Associate Professor of Biology
Current Research and Scholarly InterestsOur goal is to understand how brain circuits mediate motivated behaviors and how maladaptive changes in these circuits cause mood disorders. To achieve this goal, we focus on studying the neural circuits for pain and addiction, as both trigger highly motivated behaviors, whereas, transitioning from acute to chronic pain or from recreational to compulsive drug use involves maladaptive changes of the underlying neuronal circuitry.
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Alan G. Cheng, MD
Edward C. and Amy H. Sewall Professor in the School of Medicine, Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsActive Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated. Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage.
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E.J. Chichilnisky
John R. Adler Professor, Professor of Neurosurgery and of Ophthalmology and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsFunctional circuitry of the retina and design of retinal prostheses
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Yueh-hsiu Chien
Professor of Microbiology & Immunology
Current Research and Scholarly InterestsContribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses.
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Wah Chiu
Wallenberg-Bienenstock Professor and Professor of Bioengineering and, by courtesy, of Microbiology and Immunology
Current Research and Scholarly InterestsMy research includes methodology improvements in single particle cryo-EM for atomic resolution structure determination of molecules and molecular machines, as well as in cryo-ET of cells and organelles towards subnanometer resolutions. We collaborate with many researchers around the country and outside the USA on understanding biological processes such as protein folding, virus assembly and disassembly, pathogen-host interactions, signal transduction, and transport across cytosol and membranes.
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Eun Young Choi, PhD
Instructor, Neurosurgery
Current Research and Scholarly InterestsDr. Choi is broadly interested in mapping the brain’s connectivity and characterizing its functional dynamics using advanced neuroimaging and clinical neurophysiological methods, as well as translating this information to identify individual-specific neurosurgical targets and treatment strategies using neuromodulation (e.g., deep brain stimulation). Her prior work has mapped the functional and connectional organization of the cortex, striatum, and thalamus using neuroimaging and NHP neuroanatomical tract-tracing. She is currently focused on the use of thalamic deep brain stimulation to improve memory and attention in traumatic brain injury and Alzheimer’s disease, and the development of precise, individual-specific adult and pediatric brain atlases and network maps.
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Danny Hung-Chieh Chou
Associate Professor of Pediatrics (Endocrinology) and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur research program integrates concepts of chemical biology, protein engineering and structure biology to design new therapeutic leads and generate probes to study biological processes. A key focus of our lab is insulin, an essential hormone in our body to reduce blood glucose levels. We generate synthetic libraries of insulin analogs to select for chemical probes, and investigate natural insulin molecules (e.g. from the venom of fish-hunting cone snails!) to develop novel therapeutic candidates. We are especially interested in using chemical and enzymatic synthesis to create novel chemical entities with enhanced properties, and leverage the strong expertise of our collaborators to apply our skill sets in the fields of cancer biology, immunology and pain research. Our ultimate goal is to translate our discovery into therapeutic interventions in human diseases.
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Steven Chu
William R. Kenan Jr. Professor, Professor of Molecular and Cellular Physiology and of Energy Science and Engineering
Current Research and Scholarly InterestsSynthesis, functionalization and applications of nanoparticle bioprobes for molecular cellular in vivo imaging in biology and biomedicine. Linear and nonlinear difference frequency mixing ultrasound imaging. Lithium metal-sulfur batteries, new approaches to electrochemical splitting of water. CO2 reduction, lithium extraction from salt water
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Thomas Clandinin
Shooter Family Professor
Current Research and Scholarly InterestsThe Clandinin lab focuses on understanding how neuronal circuits assemble and function to perform specific computations and guide behavior. Taking advantage of a rich armamentarium of genetic tools available in the fruit fly, combined with imaging, physiology and analytical techniques drawn from systems neuroscience, we examine a variety of visual circuits.
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David Clark
Professor of Anesthesiology, Perioperative and Pain Medicine (MSD)
BioMy career is dedicated to improving the safety, effectiveness and availability of pain relief. Both the needs and opportunities in these areas are limitless. I have had the good fortune of working as a clinician, teacher and scientist at Stanford University and the Palo Alto VA hospital for more than two decades.
Much of my time is spent on laboratory, translational and clinical research. In the laboratory, we are pursuing several projects related to the questions of why pain sometimes becomes chronic after injuries and why opioids lose their effectiveness over time. Alterations in endogenous pain control mechanisms and the involvement of the adaptive system of immunity are central to these investigations. We would like to find ways to maximize functional recovery after surgery and other forms of trauma while minimizing the risks of analgesic use. This work involves local, national and international collaborations. Clinical trials work involves establishing the efficacy of novel forms of analgesic therapy as well as the comparative effectiveness of long-established approaches to controlling common forms of pain such as low back pain. This spectrum of pain-related pursuits continues to evolve with the rapid expansion of the field. -
Eve Clark
Richard Lyman Professor in the Humanities, Emerita
BioI am interested in first language acquisition, the acquisition of meaning, acquisitional principles in word-formation compared across children and languages, and general semantic and pragmatic issues in the lexicon and in language use. I am currently working on the kinds of pragmatic information adults offer small children as they talk to them, and on children's ability to make use of this information as they make inferences about unfamiliar meanings and about the relations between familiar and unfamiliar words. I am interested in the inferences children make about where to 'place' unfamiliar words, how they identify the relevant semantic domains, and what they can learn about conventional ways to say things based on adult responses to child errors during acquisition. All of these 'activities' involve children and adults placing information in common ground as they interact. Another current interest of mine is the construction of verb paradigms: how do children go from using a single verb form to using forms that contrast in meaning -- on such dimensions as person, number, and tense? How do they learn to distinguish the meanings of homophones? To what extent do they make use of adult input to discern the underlying structure of the system? And how does conversation with more expert speakers (usually adults) foster the acquisition of a first language? I am particularly interested in the general role of practice along with feedback here.
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Michael F. Clarke, M.D.
Karel H. and Avice N. Beekhuis Professor of Cancer Biology
Current Research and Scholarly InterestsDr. Clarke maintains a laboratory focused on two areas of research: i) the control of self-renewal of normal stem cells and diseases such as cancer and hereditary diseases; and ii) the identification and characterization of cancer stem cells. His laboratory is investigating how perturbations of stem cell regulatory machinery contributes to human disease. In particular, the laboratory is investigating epigenetic regulators of self renewal, the process by which stem cells regenerate themselves.
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Maria Inmaculada Cobos Sillero
Associate Professor of Pathology
Current Research and Scholarly InterestsOur lab uses cellular and molecular methods, single-cell technology, and quantitative histology to study human neurodegenerative diseases. Current projects include:
- Using single-cell RNA-sequencing to understand selective vulnerability and disease progression in human Alzheimer’s disease brain
- Investigating mechanisms of tau-related neurodegeneration in human brain
- Studying the neocortical and limbic systems in Diffuse Lewy Body Disease (DLBD) at the single cell level -
Jennifer R. Cochran
Vice President for SLAC National Accelerator Laboratory and for Strategic Initiatives, Addie and Al Macovski Professor, Professor of Bioengineering and, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsMolecular Engineering, Protein Biochemistry, Biotechnology, Cell and Tissue Engineering, Molecular Imaging, Chemical Biology
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Stanley N. Cohen, MD
Kwoh-Ting Li Professor in the School of Medicine, Professor of Genetics and of Medicine
On Partial Leave from 06/04/2025 To 07/16/2026Current Research and Scholarly InterestsWe study mechanisms that affect the expression and decay of normal and abnormal mRNAs, and also RNA-related mechanisms that regulate microbial antibiotic resistance. A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of genes.
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Todd Coleman
Associate Professor of Bioengineering and, by courtesy, of Electrical Engineering
BioTodd P. Coleman is an Associate Professor in the Department of Bioengineering, and by courtesy, Electrical Engineering at Stanford University. He received B.S. degrees in electrical engineering (summa cum laude), as well as computer engineering (summa cum laude) from the University of Michigan (Go Blue). He received M.S. and Ph.D. degrees from MIT in electrical engineering and computer science. He did postdoctoral studies at MIT and Mass General Hospital in quantitative neuroscience. He previously was a faculty member in the Departments of Electrical & Computer Engineering and Bioengineering at the University of Illinois, Urbana-Champaign, and the University of California, San Diego, respectively. Dr. Coleman’s research is very multi-disciplinary, using tools from applied probability, physiology, and bioelectronics. Examples include, for instance, optimal transport methods in high-dimensional uncertainty quantification and developing technologies and algorithms to monitor and modulate physiology of the nervous systems in the brain and visceral organs. He has served as a Principal Investigator on grants from the NSF, NIH, Department of Defense, and multiple private foundations. Dr. Coleman is an inventor on 10 granted US patents. He has been selected as a Gilbreth Lecturer for the National Academy of Engineering, a TEDMED speaker, and a Fellow of IEEE as well as the American Institute for Medical and Biological Engineering. He recently served as Chair of the National Academies Standing Committee on Biotechnology Capabilities and National Security Needs.
