Bio-X


Showing 1-63 of 63 Results

  • Nicholas Haber

    Nicholas Haber

    Assistant Professor of Education and, by courtesy, of Computer Science

    Current Research and Scholarly InterestsI use AI models of of exploratory and social learning in order to better understand early human learning and development, and conversely, I use our understanding of early human learning to make robust AI models that learn in exploratory and social ways. Based on this, I develop AI-powered learning tools for children, geared in particular towards the education of those with developmental issues such as the Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder, in the mold of my work on the Autism Glass Project. My formal graduate training in pure mathematics involved extending partial differential equation theory in cases involving the propagation of waves through complex media such as the space around a black hole. Since then, I have transitioned to the use of machine learning in developing both learning tools for children with developmental disorders and AI and cognitive models of learning.

  • Elizabeth Hadly

    Elizabeth Hadly

    Paul S. and Billie Achilles Professor of Environmental Biology, Professor of Earth System Science, Senior Fellow at the Woods Institute for the Environment and Professor, by courtesy, of Earth and Planetary Sciences
    On Leave from 10/01/2023 To 06/30/2024

    Current Research and Scholarly InterestsElizabeth Hadly and her lab probe how perturbations such as climatic change and human modification of the environment influence the evolution and ecology of animals.

  • Lou Halamek

    Lou Halamek

    Professor of Pediatrics (Neonatology) and, by courtesy, of Obstetrics and Gynecology

    Current Research and Scholarly Interests1. development of hospital operations centers coupled with sophisticated simulation capabilities
    2. re-creation of near misses and adverse events
    3. optimizing human and system performance during resuscitation
    4. optimizing pattern recognition and situational awareness at the bedside
    5. evaluation and optimization of debriefing
    6. patient simulator design

  • Joachim Hallmayer

    Joachim Hallmayer

    Professor of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsPrincipal Investigator
    Infrastructure to facilitate discovery of autism genes
    The purpose of this project is to facilitate the discovery of the genes that contribute autism by maintaining an infrastructure which research groups studying the genetics of autism can work collaboratively. This will be
    accomplished through workshops, a Virtual Private Network, and access to a database that includes phenotype and genotype data from all participating groups.

    Principal Investigator
    A California Population-Based Twin Study of Autism
    This will address several fundamental questions: (1) What is the heritability of autism (2) What is the contribution of genetic factors to variation in symptom dimensions? (3) Is there a continuum between the quantitative neurocognitive traits and clinical disorder? (4) What proportion of the variance in the neurocognitive traits is accounted for by genetic and non-genetic factors?

    Co-Investigator
    Center for Integrating Ethics in Genetics Research(Cho)
    The goal of this project is to serve as a center of excellence in neurogenetics research, to develop a national model for bench, to bedside research ethics consultation, and to provide training opportunity in biomedical ethics.

    Co-Investigator
    Gene, Brain and Behavior in Turner Syndrome(Reiss)
    The primary objective of this project is to use advanced, multi-modal magnetic resonance imaging (MRI) techniques, analyses of X chromosome parent-of-origin and cognitive-behavioral assessment to elucidate the effects of monosomy and X-linked imprinting on neurodevelopment and neural function in a large cohort of young girls with Turner syndrome, pre-estrogen replacement.

    Project Director
    Project F: Genomic Analysis in narcolepsy cataplexy
    The goal of the project is to locate genes outside the HLA region that influence susceptibility to narcolepsy. In order to localize these genes we will carry out a linkage and association study in the most extensive world-wide collection of DNAs from well-characterized patients with narcolepsy and their families.

  • May Han, MD

    May Han, MD

    Associate Professor of Neurology (Adult Neurology)

    Current Research and Scholarly InterestsMultiple sclerosis
    Neuromyelitis optica
    Autoimmune CNS disorders

  • Summer Han

    Summer Han

    Associate Professor (Research) of Neurosurgery, of Medicine (Biomedical Informatics) and, by courtesy, of Epidemiology and Population Health

    Current Research and Scholarly InterestsMy current research focuses on understanding the genetic and environmental etiology of complex disease and developing and evaluating efficient screening strategies based on etiological understanding. The areas of my research interests include statistical genetics, molecular epidemiology, cancer screening, health policy modeling, and risk prediction modeling. I have developed various statistical methods to analyze high-dimensional data to identify genetic and environmental risk factors and their interactions for complex disease.

  • Philip C. Hanawalt

    Philip C. Hanawalt

    Dr. Morris Herzstein Professor in Biology, Emeritus

    Current Research and Scholarly InterestsMy current interest includes two principal areas:

    1. The molecular basis for diseases in which the pathway of transcription-coupled DNA repair is defective, including Cockyne syndrome (CS) and UV-sensitive syndrome (UVSS). Patients are severely sensitive to sunlight but get no cancers. See Hanawalt & Spivak, 2008, for review.

    2. Transcription arrest by guanine-rich DNA sequences and non-canonical secondary structures. Transcription collisions with replication forks.

  • Ronald Hanson

    Ronald Hanson

    Clarence J. and Patricia R. Woodard Professor of Mechanical Engineering

    Current Research and Scholarly InterestsProfessor Hanson has been an international leader in the development of laser-based diagnostic methods for combustion and propulsion, and in the development of modern shock tube methods for accurate determination of chemical reaction rate parameters needed for modeling combustion and propulsion systems. He and his students have made several pioneering contributions that have impacted the pace of propulsion research and development worldwide.

  • Pehr Harbury

    Pehr Harbury

    Associate Professor of Biochemistry

    Current Research and Scholarly InterestsScientific breakthroughs often come on the heels of technological advances; advances that expose hidden truths of nature, and provide tools for engineering the world around us. Examples include the telescope (heliocentrism), the Michelson interferometer (relativity) and recombinant DNA (molecular evolution). Our lab explores innovative experimental approaches to problems in molecular biochemistry, focusing on technologies with the potential for broad impact.

  • Antonio Hardan, M.D.

    Antonio Hardan, M.D.

    Professor of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsThe neurobiology of autism
    Neuroimaging in individuals with autism
    Psychopharmacological treatment of children and adults with autism and/or developmental disorders
    The neurobiology and innovative interventions of several neurogenic disorders including DiGeorge Syndrome (Velocardiofacial syndrome; 22q11.2 mutations), PTEN mutations, and Phelan McDermid Syndrome (22q13 mutations).

  • Brian A. Hargreaves

    Brian A. Hargreaves

    Professor of Radiology (Radiological Sciences Laboratory) and, by courtesy, of Electrical Engineering and of Bioengineering

    Current Research and Scholarly InterestsI am interested in magnetic resonance imaging (MRI) applications and augmented reality applications in medicine. These include abdominal, breast and musculoskeletal imaging, which require development of faster, quantitative, and more efficient MRI methods that provide improved diagnostic contrast compared with current methods. My work includes novel excitation schemes, efficient imaging methods and reconstruction tools and augmented reality in medicine.

  • Keren Haroush

    Keren Haroush

    Assistant Professor of Neurobiology

    Current Research and Scholarly InterestsOur laboratory studies the mechanisms by which highly complex behaviors are mediated at the neuronal level, mainly focusing on the example of dynamic social interactions and the neural circuits that drive them. From dyadic interactions to group dynamics and collective decision making, the lab seeks a mechanistic understanding for the fundamental building blocks of societies, such as cooperation, empathy, fairness and reciprocity.

  • James Harris

    James Harris

    James and Elenor Chesebrough Professor in the School of Engineering, Emeritus

    BioHarris utilizes molecular beam epitaxy (MBE) of III-V compound semiconductor materials to investigate new materials for electronic and optoelectronic devices. He utilizes heterojunctions, superlattices, quantum wells, and three-dimensional self-assembled quantum dots to create metastable engineered materials with novel or improved properties for electronic and optoelectronic devices. His early work in the 1970's demonstrating a practical heterojunction bipolar transistor led to their application in every mobile phone today and record setting solar cell efficiency. He has recently focused on three areas: 1) integration of photonic devices and micro optics for creation of new minimally invasive bio and medical systems for micro-array and neural imaging and 2) application of nanostructures semiconductors for the acceleration of electrons using light, a dielectric Laser Accelerator (DLA), and 3) novel materials and nano structuring for high efficiency solar cells and photo electrochemical water splitting for the generation of hydrogen.

  • Trevor Hastie

    Trevor Hastie

    John A. Overdeck Professor, Professor of Statistics and of Biomedical Data Sciences
    On Partial Leave from 01/01/2024 To 03/31/2024

    Current Research and Scholarly InterestsFlexible statistical modeling for prediction and representation of data arising in biology, medicine, science or industry. Statistical and machine learning tools have gained importance over the years. Part of Hastie's work has been to bridge the gap between traditional statistical methodology and the achievements made in machine learning.

  • Melanie Hayden Gephart

    Melanie Hayden Gephart

    Professor of Neurosurgery and, by courtesy, of Neurology

    BioI am a brain tumor neurosurgeon, treating patients with primary and metastatic brain tumors. I treat patients with malignant and benign tumors, including glioma, brain metastases, meningioma, and vestibular schwannomas. I direct the Stanford Brain Tumor Center and the Stanford Brain Metastasis Consortium, collaborative unions of physicians and scientists looking to improve our understanding and treatment of brain tumors. My laboratory seeks greater understanding of the mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We study how rare cancer cell populations survive and migrate in the brain, inadvertently supported by native brain cells. We develop novel cell free nucleic acid biomarkers to track brain cancer treatment response, relapse, and neurotoxicity. Our bedside-to-bench-to-bedside research model builds on a foundation of generously donated patient samples, where we test mechanisms of brain cancer growth, develop novel pre-clinical models that reliably recapitulate the human disease, and facilitate clinical trials of new treatments for patients with brain cancer.

    www.GephartLab.com
    www.GBMseq.org
    https://stan.md/BrainMets
    @HaydenGephartMD

  • Zihuai He

    Zihuai He

    Assistant Professor (Research) of Neurology (Neurology Research Faculty), of Medicine (BMIR) and, by courtesy, of Biomedical Data Science

    Current Research and Scholarly InterestsStatistical genetics and other omics to study Alzheimer's disease.

  • Boris Heifets

    Boris Heifets

    Assistant Professor of Anesthesiology, Perioperative and Pain Medicine (Adult MSD) and, by courtesy, of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsHarnessing synaptic plasticity to treat neuropsychiatric disease

  • Jeremy J. Heit, MD, PhD

    Jeremy J. Heit, MD, PhD

    Associate Professor of Radiology (Neuroimaging and Neurointervention) and, by courtesy, of Neurosurgery

    Current Research and Scholarly InterestsOur research seeks to advance our understanding of cerebrovascular disease and to develop new minimally invasive treatments for these diseases. We study ischemic and hemorrhagic stroke, cerebral aneurysms, delayed cerebral ischemia, cerebral arteriovenous malformations (AVMs), dural arteriovenous fistulae, and other vascular diseases of the brain. We use state-of-the-art neuroimaging techniques to non-invasively study these diseases, and we are developing future endovascular technologies to advance neurointerventional surgery.

    www.heitlab.com

  • H. Craig Heller

    H. Craig Heller

    Lorry I. Lokey/Business Wire Professor

    Current Research and Scholarly InterestsNeurobiology of sleep, circadian rhythms, regulation of body temperature, mammalian hibernation, and human exercise physiology. Currently applying background in sleep and circadian neurobiology the understanding and correcting the learning disability of Down Syndrome.

  • Stefan Heller

    Stefan Heller

    Edward C. and Amy H. Sewall Professor in the School of Medicine and Professor of Otolaryngology - Head & Neck Surgery (OHNS)

    Current Research and Scholarly InterestsOur research focuses on the inner ear, from its earliest manifestation as one of the cranial placodes until it has developed into a mature and functioning organ. We are interested in how the sensory epithelia of the inner ear that harbor the sensory hair cells develop, how the cells mature, and how these epithelia respond to toxic insults. The overarching goal of this research is to find ways to regenerate lost sensory hair cells in mammals.

  • Jill Helms

    Jill Helms

    Professor of Surgery (Plastic & Reconstructive Surgery)

    Current Research and Scholarly InterestsDr. Helms' research interests center around regenerative medicine and craniofacial development.

  • Jaimie Henderson, MD

    Jaimie Henderson, MD

    John and Jene Blume - Robert and Ruth Halperin Professor, Professor of Neurosurgery and, by courtesy, of Neurology

    Current Research and Scholarly InterestsMy research interests encompass several areas of stereotactic and functional neurosurgery, including frameless stereotactic approaches for therapy delivery to deep brain nuclei; cortical physiology and its relationship to normal and pathological movement; brain-computer interfaces; and the development of novel neuromodulatory techniques for the treatment of movement disorders, epilepsy, pain, and other neurological diseases.

  • Rod Hentz

    Rod Hentz

    Professor of Surgery, Emeritus

    Current Research and Scholarly Interests1. Nerve regeneration and repair, evaluation of repair methods, modalities to enhance peripheral nerve regeneration, development of improved methods to analyze nerve regeneration.

    2. Implementation of functional neuromuscular stimulation to paralytic deformities.

    3. Computer modeling of upper limb function.

  • Tina Hernandez-Boussard

    Tina Hernandez-Boussard

    Professor of Medicine (Biomedical Informatics), of Biomedical Data Science, of Surgery and, by courtesy, of Epidemiology and Population Health

    Current Research and Scholarly InterestsMy background and expertise is in the field of computational biology, with concentration in health services research. A key focus of my research is to apply novel methods and tools to large clinical datasets for hypothesis generation, comparative effectiveness research, and the evaluation of quality healthcare delivery. My research involves managing and manipulating big data, which range from administrative claims data to electronic health records, and applying novel biostatistical techniques to innovatively assess clinical and policy related research questions at the population level. This research enables us to create formal, statistically rigid, evaluations of healthcare data using unique combinations of large datasets.

  • Rogelio A. Hernández-López

    Rogelio A. Hernández-López

    Assistant Professor of Bioengineering and of Genetics

    Current Research and Scholarly InterestsOur group works at the interface of mechanistic, synthetic, and systems biology to understand and program cellular recognition, communication, and organization. We are currently interested in engineering biomedical relevant cellular behaviors for cancer immunotherapy.

  • Daniel Herschlag

    Daniel Herschlag

    Professor of Biochemistry and, by courtesy, of Chemical Engineering
    On Leave from 06/01/2023 To 04/30/2024

    Current Research and Scholarly InterestsOur research is aimed at understanding the chemical and physical behavior underlying biological macromolecules and systems, as these behaviors define the capabilities and limitations of biology. Toward this end we study folding and catalysis by RNA, as well as catalysis by protein enzymes.

  • Lambertus Hesselink

    Lambertus Hesselink

    Professor of Electrical Engineering and, by courtesy of Applied Physics

    BioHesselink's research encompasses nano-photonics, ultra high density optical data storage, nonlinear optics, optical super-resolution, materials science, three-dimensional image processing and graphics, and Internet technologies.

  • Shaul Hestrin, PhD

    Shaul Hestrin, PhD

    Professor of Comparative Medicine

    Current Research and Scholarly InterestsThe main interest of my lab is to understand how the properties of neocortical neurons, the circuits they form and the inputs they receive give rise to neuronal activity and behavior. Our approach includes behavioral studies, two-photon calcium imaging, in vivo whole cell recording in behaving animals and optogenetic methods to activate or to silence the activity of cortical neurons.

  • Brian Hie

    Brian Hie

    Assistant Professor of Chemical Engineering

    BioI am an Assistant Professor of Chemical Engineering and Data Science at Stanford University, and an Innovation Investigator at Arc Institute. I supervise the Laboratory of Evolutionary Design, where we conduct research at the intersection of biology and machine learning.

    I was previously a Stanford Science Fellow in the Stanford University School of Medicine and a Visiting Researcher at Meta AI. I completed my Ph.D. at MIT CSAIL and was an undergraduate at Stanford University. I have also previously worked at Google X, Illumina, and Salesforce.

  • William Hiesinger, MD

    William Hiesinger, MD

    Associate Professor of Cardiothoracic Surgery (Adult Cardiac Surgery)

    BioDr. Hiesinger is a board-certified, fellowship-trained specialist in adult cardiac surgery. He is also an assistant professor in the Department of Cardiothoracic Surgery at Stanford University School of Medicine.

    Dr. Hiesinger’s clinical focus encompasses the full spectrum of cardiothoracic conditions and treatment approaches, such as heart transplantation, mitral and aortic valve repair, surgical treatment for hypertrophic cardiomyopathy, coronary artery bypass, and complex thoracic aortic procedures. He serves as Surgical Director of the Stanford Mechanical Circulatory Support Program, where he leads and directs the surgical implantation of ventricular assist devices (VADs) in patients with end-stage heart failure.

    The National Institutes of Health and the Thoracic Surgery Foundation have awarded funds to support Dr. Hiesinger’s research. In the Stanford Cardiothoracic Therapeutics and Surgery Laboratory, Dr. Hiesinger's research spans the disciplines of computer science and cardiovascular biology, and he endeavors to build novel foundational deep learning systems designed to better represent and process high-dimensional inputs and apply these systems towards clinical problems. Additionally, his lab investigates bioengineered devices, tissue engineering, and angiogenic cytokine therapy for the treatment of heart failure.

    He has published extensively and his work has appeared in Nature Communications, Nature Machine Intelligence, the Journal of Heart and Lung Transplantation, Circulation Heart Failure, the Journal of Thoracic and Cardiovascular Surgery, Journal of Vascular Surgery, and elsewhere.

    He teaches courses on cardiothoracic surgery skills. He also advises surgeons of the future.

    Dr. Hiesinger has won awards for his research and scholarship, including the Surgical Resident of the Year Award, Jonathan E. Rhoads Research Award, Clyde F. Baker Research Prize, and I.S. Ravdin Prize, all from his alma mater, the University of Pennsylvania. He was a finalist for the Vivien Thomas Young Investigator Award from the American Heart Association.

    Dr. Hiesinger is a member of the American Association For Thoracic Surgery and serves on the Cardiac Surgery Biology Club. He is also a member of the Society of Thoracic Surgeons and serves on the Workforce on Surgical Treatment of End-Stage Cardiopulmonary Disease national committee as well as the American Heart Association Council for Cardiothoracic and Vascular Surgery.

  • John Higgins

    John Higgins

    Professor of Pathology

    Current Research and Scholarly InterestsI work as a diagnostic surgical pathologist doing translational research in renal neoplasia and medical renal disease and neoplastic and medical liver disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology.

  • Lynn Hildemann

    Lynn Hildemann

    Senior Associate Dean for Education and Professor of Civil and Environmental Engineering

    BioLynn Hildemann's current research areas include the sources and dispersion of airborne particulate matter indoors, and assessment of human exposure to air pollutants.

    Prof. Hildemann received BS, MS, and PhD degrees in environmental engineering science from the California Institute of Technology. She is an author on >100 peer-reviewed publications, including two with over 1000 citations each, and another 6 with over 500 citations each. She has been honored with Young Investigator Awards from NSF and ONR, the Kenneth T. Whitby Award from the AAAR (1998), and Stanford's Gores Award for Teaching Excellence (2013); she also was a co-recipient of Atmospheric Environment’s Haagen-Smit Outstanding Paper Award (2001).

    She has served on advisory committees for the Bay Area Air Quality Management District and for the California Air Resources Board. She has been an Associate Editor for Environmental Science & Technology, and Aerosol Science and Technology, and has served on the advisory board for the journal Environmental Science & Technology.

    At Stanford, Prof. Hildemann has been chair of the Department of Civil & Environmental Engineering, and served as an elected member of the Faculty Senate. She has chaired the School of Engineering Library Committee, the University Committee on Judicial Affairs, and the University Breadth Governance Board.

  • Daniel Ho

    Daniel Ho

    William Benjamin Scott & Luna M. Scott Professor of Law, Professor of Political Science, Senior Fellow at the Stanford Institute for Economic Policy Research, at the Stanford Institute for HAI and Professor, by courtesy, of Computer Science

    BioDaniel E. Ho is the William Benjamin Scott and Luna M. Scott Professor of Law, Professor of Political Science, Professor of Computer Science (by courtesy), Senior Fellow at Stanford's Institute for Human-Centered Artificial Intelligence, and Senior Fellow at the Stanford Institute for Economic Policy Research at Stanford University. He is a Faculty Fellow at the Center for Advanced Study in the Behavioral Sciences and is Director of the Regulation, Evaluation, and Governance Lab (RegLab). Ho serves on the National Artificial Intelligence Advisory Commission (NAIAC), advising the White House on artificial intelligence, as Senior Advisor on Responsible AI at the U.S. Department of Labor, and as a Public Member of the Administrative Conference of the United States (ACUS). He received his J.D. from Yale Law School and Ph.D. from Harvard University and clerked for Judge Stephen F. Williams on the U.S. Court of Appeals, District of Columbia Circuit.

  • Keith Hodgson

    Keith Hodgson

    David Mulvane Ehrsam and Edward Curtis Franklin Professor of Chemistry and Professor of Photon Science at SLAC

    BioCombining inorganic, biophysical and structural chemistry, Professor Keith Hodgson investigates how structure at molecular and macromolecular levels relates to function. Studies in the Hodgson lab have pioneered the use of synchrotron x-radiation to probe the electronic and structural environment of biomolecules. Recent efforts focus on the applications of x-ray diffraction, scattering and absorption spectroscopy to examine metalloproteins that are important in Earth’s biosphere, such as those that convert nitrogen to ammonia or methane to methanol.

    Keith O. Hodgson was born in Virginia in 1947. He studied chemistry at the University of Virginia (B.S. 1969) and University of California, Berkeley (Ph.D. 1972), with a postdoctoral year at the ETH in Zurich. He joined the Stanford Chemistry Department faculty in 1973, starting up a program of fundamental research into the use of x-rays to study chemical and biological structure that made use of the unique capabilities of the Stanford Synchrotron Radiation Lightsource (SSRL). His lab carried out pioneering x-ray absorption and x-ray crystallographic studies of proteins, laying the foundation for a new field now in broad use worldwide. In the early eighties, he began development of one of the world's first synchrotron-based structural molecular biology research and user programs, centered at SSRL. He served as SSRL Director from 1998 to 2005, and SLAC National Accelerator Laboratory (SLAC) Deputy Director (2005-2007) and Associate Laboratory Director for Photon Science (2007-2011).

    Today the Hodgson research group investigates how molecular structure at different organizational levels relates to biological and chemical function, using a variety of x-ray absorption, diffraction and scattering techniques. Typical of these molecular structural studies are investigations of metal ions as active sites of biomolecules. His research group develops and utilizes techniques such as x-ray absorption and emission spectroscopy (XAS and XES) to study the electronic and metrical details of a given metal ion in the biomolecule under a variety of natural conditions.

    A major area of focus over many years, the active site of the enzyme nitrogenase is responsible for conversion of atmospheric di-nitrogen to ammonia. Using XAS studies at the S, Fe and Mo edge, the Hodgson group has worked to understand the electronic structure as a function of redox in this cluster. They have developed new methods to study long distances in the cluster within and outside the protein. Studies are ongoing to learn how this cluster functions during catalysis and interacts with substrates and inhibitors. Other components of the protein are also under active study.

    Additional projects include the study of iron in dioxygen activation and oxidation within the binuclear iron-containing enzyme methane monooxygenase and in cytochrome oxidase. Lab members are also investigating the role of copper in electron transport and in dioxygen activation. Other studies include the electronic structure of iron-sulfur clusters in models and enzymes.

    The research group is also focusing on using the next generation of x-ray light sources, the free electron laser. Such a light source, called the LCLS, is also located at SLAC. They are also developing new approaches using x-ray free electron laser radiation to image noncrystalline biomolecules and study chemical reactivity on ultrafast time scales.

  • Andrew R. Hoffman

    Andrew R. Hoffman

    Professor of Medicine (Endocrinology)

    Current Research and Scholarly InterestsMechanism of genomic imprinting of insulin like growth factor-2 and other genes.Long range chromatin interactions Role of histone modifications and DNA methylation in gene expression.

  • Susan Holmes

    Susan Holmes

    Professor of Statistics

    Current Research and Scholarly InterestsOur lab has been developing tools for the analyses of complex data structures, extending work on multivariate data to structured multitable table that include graphs, networks and trees as well as categorical and continuous measurements.
    We created and support the Bioconductor package phyloseq for the analyses of microbial ecology data from the microbiome. We have specialized in developing interactive graphical visualization tools for doing reproducible research in biology.

  • Mark Holodniy

    Mark Holodniy

    Professor of Medicine (Infectious Diseases)

    Current Research and Scholarly InterestsMy research program is currently focused in three areas: 1) Translational research (viral evolution and antiviral resistance prevalence and development), 2) Clinical trials (diagnostic assay/medical device, antimicrobials and immunomodulators), and 3) Health services research focusing on public health, infectious diseases and clinical outcomes.

  • David S. Hong

    David S. Hong

    Associate Professor of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)

    Current Research and Scholarly InterestsDr. Hong is a child and adolescent psychiatrist and clinician-scientist. His responsibilities span clinical care, teaching/mentorship, and research, with a unifying theme of advancing a developmental cognitive framework as applied to psychiatric conditions. Using this core premise, he work encompasses multiple domains: specialized clinical care, fellowship training, research mentorship, and elaborating the role of sex-specific determinants of development, one of the greatest contributors to individual developmental variation.

    His lab investigates genetic and hormonal influences underlying sex differences in child psychiatric conditions. Sex has emerged as a critical variable driving differences in the phenomenology, course, and treatment of many mental health disorders. Unfortunately, an understanding of the biological mechanisms driving these effects are limited. By applying innovative neuroimaging and multiomic approaches, Dr. Hong seeks to provide a deeper understanding of the connection between sex-specific effects and complex psychiatric diseases. To do so, research in the Hong Lab focuses on the role of genes on the X and Y chromosomes, as well as circulating sex hormones on brain development, cognition, and behavior. The lab broadly aims to elucidate the changing nature of these mechanisms across various stages of development.

    Another area of focus is the implementation of clinical informatics in child psychiatry and the development of digital mental health tools. As co-Director of the Mental Health Technology and Innovation Hub, Dr. Hong is helping to develop clinical and research infrastructure within the Department of Psychiatry and Behavioral Sciences to advance development of mobile mental health resources that will improve efficacy and access to mental health care.

  • Guosong Hong

    Guosong Hong

    Assistant Professor of Materials Science and Engineering

    BioGuosong Hong's research aims to bridge materials science and neuroscience, and blur the distinction between the living and non-living worlds by developing novel neuroengineering tools to interrogate and manipulate the brain. Specifically, the Hong lab is currently developing ultrasound, infrared, and radiofrequency-based in-vivo neural interfaces with minimal invasiveness, high spatiotemporal resolution, and cell-type specificity.

    Dr. Guosong Hong received his PhD in chemistry from Stanford University in 2014, and then carried out postdoctoral studies with at Harvard University. Dr. Hong joined Stanford Materials Science and Engineering and Neurosciences Institute as an assistant professor in 2018. He is a recipient of the NIH Pathway to Independence (K99/R00) Award, the MIT Technology Review ‘35 Innovators Under 35’ Award, the Science PINS Prize for Neuromodulation, the NSF CAREER Award, the Walter J. Gores Award for Excellence in Teaching, and the Rita Allen Foundation Scholars Award.

  • Mark Horowitz

    Mark Horowitz

    Fortinet Founders Chair of the Department of Electrical Engineering , Yahoo! Founders Professor in the School of Engineering and Professor of Computer Science

    BioProfessor Horowitz initially focused on designing high-performance digital systems by combining work in computer-aided design tools, circuit design, and system architecture. During this time, he built a number of early RISC microprocessors, and contributed to the design of early distributed shared memory multiprocessors. In 1990, Dr. Horowitz took leave from Stanford to help start Rambus Inc., a company designing high-bandwidth memory interface technology. After returning in 1991, his research group pioneered many innovations in high-speed link design, and many of today’s high speed link designs are designed by his former students or colleagues from Rambus.

    In the 2000s he started a long collaboration with Prof. Levoy on computational photography, which included work that led to the Lytro camera, whose photographs could be refocused after they were captured.. Dr. Horowitz's current research interests are quite broad and span using EE and CS analysis methods to problems in neuro and molecular biology to creating new agile design methodologies for analog and digital VLSI circuits. He remains interested in learning new things, and building interdisciplinary teams.

  • Hadi Hosseini

    Hadi Hosseini

    Associate Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)

    Current Research and Scholarly InterestsOur lab’s research portfolio crosses multiple disciplines including computational neuropsychiatry, cognitive neuroscience, multimodal neuroimaging and neurocognitive rehabilitation. Our computational neuropsychiatry research mainly involves investigating alterations in the organization of connectome in various neurodevelopmental and neurocognitive disorders using state of the art neuroimaging techniques (fMRI, sMRI, DWI, functional NIRS) combined with novel computational methods (graph theoretical and multivariate pattern analyses).

    The ultimate goal of our research is to translate the findings from computational neuropsychiatry research toward developing personalized interventions. We have been developing personalized interventions that integrate computerized cognitive rehabilitation, real-time functional brain imaging and neurofeedback, as well as virtual reality (VR) tailored toward targeted rehabilitation of the affected brain networks in patients with neurocognitive disorders.

  • David Hovsepian, MD

    David Hovsepian, MD

    Clinical Professor, Radiology

    Current Research and Scholarly InterestsI am interested in the diagnosis and treatment of vascular malformations in both children and adults; all aspects of gynecological intervention, especially uterine fibroid embolization; and in the developing sciences of quality, safety, and radiology informatics.

  • Roger Howe

    Roger Howe

    William E. Ayer Professor of Electrical Engineering, Emeritus

    BioDesign and fabrication of sensors and actuators using micro and nanotechnologies, with applications to information processing and energy conversion.

  • Brooke Howitt

    Brooke Howitt

    Associate Professor of Pathology

    BioDr. Howitt is a gynecologic and sarcoma pathologist, with academic interests in gynecologic mesenchymal tumors and morphologic and clinical correlates of molecular alterations in gynecologic neoplasia.

  • Michael R. Howitt

    Michael R. Howitt

    Assistant Professor of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsOur lab is broadly interested in how intestinal microbes shape our immune system to promote both health and disease. Recently we discovered that a type of intestinal epithelial cell, called tuft cells, act as sentinels stationed along the lining of the gut. Tuft cells respond to microbes, including parasites, to initiate type 2 immunity, remodel the epithelium, and alter gut physiology. Surprisingly, these changes to the intestine rely on the same chemosensory pathway found in oral taste cells. Currently, we aim to 1) elucidate the role of specific tuft cell receptors in microbial detection. 2) To understand how protozoa and bacteria within the microbiota impact host immunity. 3) Discover how tuft cells modulate surrounding cells and tissue.

  • Alison Hoyt

    Alison Hoyt

    Assistant Professor of Earth System Science and Center Fellow, by courtesy, at the Woods Institute for the Environment

    BioAlison Hoyt is an Assistant Professor of Earth System Science at Stanford. Her work focuses on understanding how biogeochemical cycles respond to human impacts, with a particular focus on the most vulnerable and least understood carbon stocks in the tropics and the Arctic. For more information, please visit her group website here: https://carboncycle.stanford.edu/

  • Dimitre Hristov

    Dimitre Hristov

    Associate Professor of Radiation Oncology (Radiation Physics)

    Current Research and Scholarly InterestsDevelopment and integration of X-ray, MRI and US imaging technologies for radiation therapy guidance; Design of synergistic approaches to radiation therapy delivery; Treatment planning optimization and modeling.

  • Aaron Hsueh

    Aaron Hsueh

    Professor of Obstetrics and Gynecology (Reproductive and Stem Cell Biology), Emeritus

    Current Research and Scholarly InterestsHormonal regulation of ovarian function; gonadotropin receptors and related genes, bioinformatic ananlyses of polypeptide hormones and receptors, follicle recruitment and GDF-9; analysis of oocyte and ovarian-expressed genes.

  • Yang Hu, MD, PhD

    Yang Hu, MD, PhD

    Associate Professor of Ophthalmology

    Current Research and Scholarly InterestsThe ultimate goal of the laboratory is to develop efficient therapeutic strategies to achieve CNS neural repair, through promoting neuroprotection, axon regeneration and functional recovery.

    More specifically, we study retinal ganglion cell (RGC) and optic nerve in various optic neuropathies including traumatic, glaucomatous and inflammatory optic nerve injuries to fully understand the molecular mechanisms of CNS neurodegeneration and axon regeneration failure.

  • KC Huang

    KC Huang

    Professor of Bioengineering and of Microbiology and Immunology

    Current Research and Scholarly InterestsHow do cells determine their shape and grow?
    How do molecules inside cells get to the right place at the right time?

    Our group tries to answer these questions using a systems biology approach, in which we integrate interacting networks of protein and lipids with the physical forces determined by the spatial geometry of the cell. We use theoretical and computational techniques to make predictions that we can verify experimentally using synthetic, chemical, or genetic perturbations.

  • Ngan F. Huang

    Ngan F. Huang

    Associate Professor of Cardiothoracic Surgery (Cardiothoracic Surgery Research) and, by courtesy, of Chemical Engineering

    Current Research and Scholarly InterestsDr. Huang's laboratory aims to understand the chemical and mechanical interactions between extracellular matrix (ECM) proteins and pluripotent stem cells that regulate vascular and myogenic differentiation. The fundamental insights of cell-matrix interactions are applied towards stem cell-based therapies with respect to improving cell survival and regenerative capacity, as well as engineered vascularized tissues for therapeutic transplantation.

  • Possu Huang

    Possu Huang

    Assistant Professor of Bioengineering

    Current Research and Scholarly InterestsProtein design: molecular engineering, method development and novel therapeutics

  • Andrew D. Huberman

    Andrew D. Huberman

    Associate Professor of Neurobiology and, by courtesy, of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsIn 2017, we developed a virtual reality platform to investigate the neural and autonomic mechanisms contributing to fear and anxiety. That involved capturing 360-degree videos of various fear-provoking situations in real life for in-lab VR movies, such as heights and claustrophobia, as well as unusual scenarios like swimming in open water with great white sharks. The primary objective of our VR platform is to develop new tools to help people better manage stress, anxiety and phobias in real-time, as an augment to in-clinic therapies.

    In May 2018, we reported the discovery of two novel mammalian brain circuits as a Research Article published in Nature. One circuit promotes fear and anxiety-induced paralysis, while the other fosters confrontational reactions to threats. This led to ongoing research into the involvement of these brain regions in anxiety-related disorders such as phobias and generalized anxiety in humans.

    In 2020, we embarked on a collaborative effort with Dr. David Spiegel's laboratory in the Stanford Department of Psychiatry and Behavioral Sciences, aimed to explore how specific respiration patterns synergize with the visual system to influence autonomic arousal and stress, and other brain states, including sleep.

    In 2023, the first results of that collaboration were published as a randomized controlled trial in Cell Reports Medicine, demonstrating that specific brief patterns of deliberate respiration are particularly effective in alleviating stress and enhancing mood, and improving sleep.

    In a 2021, our collaboration with Dr. Edward Chang, professor and chair of the Department of Neurological Surgery at the University of California, San Francisco (UCSF), was published in Current Biology, revealing that specific patterns of insular cortex neural activity may be linked to, and potentially predict, anxiety responses.

  • John Huguenard

    John Huguenard

    Professor of Neurology (Neurology Research Faculty), of Neurosurgery (Adult Neurosurgery) and, by courtesy, of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsWe are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.

  • Sohail Z Husain

    Sohail Z Husain

    Chambers-Okamura Endowed Professor of Pediatric Gastroenterology

    Current Research and Scholarly InterestsMy research delves into three broad areas of the exocrine pancreas: (1) The crucial signaling pathways that initiate and transduce pancreatitis; (2) the factors that turn on pancreatic regeneration and recovery after pancreatic injury; and (3) the mechanisms underlying drug-induced pancreatitis.

  • Ruth Huttenhain

    Ruth Huttenhain

    Assistant Professor of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsMy group deciphers how G protein-coupled receptors decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses. We exploit quantitative proteomics to capture the spatiotemporal organization of signaling networks combined with functional genomics to study their impact on physiology.

  • Gloria Hwang, MD

    Gloria Hwang, MD

    Clinical Professor, Radiology

    Current Research and Scholarly InterestsInterventional oncology, pancreatic interventions, image-guided gene therapy.

  • Joo Ha Hwang, MD, PhD

    Joo Ha Hwang, MD, PhD

    Professor of Medicine (Gastroenterology and Hepatology) and, by courtesy, of Surgery

    Current Research and Scholarly InterestsSpecialize in early detection of gastrointestinal malignancies including esophageal, gastric, pancreatic, bile duct & colon cancers. I have both a clinical & research interest in improving the early detection of gastric cancer in particular. I am the PI of the Gastric Precancerous conditions Study, a prospective study of patients with gastric intestinal metaplasia & other precancerous conditions which combines comprehensive clinical & endoscopic data with a large bio-specimen repository.