Bio-X
Showing 801-850 of 1,059 Results
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William H. Robinson, MD PhD
James W. Raitt, M.D. Professor
Current Research and Scholarly InterestsOur lab investigates the molecular mechanisms of and develops therapies to treat autoimmune and rheumatic diseases, with a focus on rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and osteoarthritis.
The overriding objectives of our laboratory are:
1. To elucidate the mechanisms underlying autoimmune and rheumatic diseases.
2. To investigate the role of innate immune inflammation in osteoarthritis.
3. To develop novel diagnostics and therapeutics -
Stephen Rock
Professor of Aeronautics and Astronautics, Emeritus
BioProfessor Rock's research interests include the application of advanced control and modeling techniques for robotic and vehicle systems (aerospace and underwater). He directs the Aerospace Robotics Laboratory in which students are involved in experimental programs designed to extend the state-of-the-art in robotic control. Areas of emphasis include planning and navigation techniques (GPS and vision-based) for autonomous vehicles; aerodynamic modeling and control for aggressive flight systems; underwater remotely-operated vehicle control; precision end-point control of manipulators in the presence of flexibility and uncertainty; and cooperative control of multiple manipulators and multiple robots. Professor Rock teaches several courses in dynamics and control.
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Stanley G. Rockson, MD
Allan and Tina Neill Professor of Lymphatic Research and Medicine
Current Research and Scholarly InterestsMy clinical research includes studies on risk factor modification in atherosclerosis and coronary artery disease; clinical trials involving medical therapies for peripheral arterial insufficiency; coronary angiogenesis; therapy of lymphedema; atherand photodynamic therapy in atherosclerosis.
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Carolyn Rodriguez
Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)
BioDr. Carolyn Rodriguez is Associate Dean for Academic Affairs, Stanford University School of Medicine and a Consultation-Liaison Psychiatrist at the Palo Alto Veterans Affairs. As the Director of the Translational Therapeutics Lab and Professor in the Department of Psychiatry and Behavioral Sciences, Dr. Rodriguez leads studies investigating the brain basis of severe mental disorders. Her landmark clinical trials pioneer rapid-acting treatments for illnesses including Obsessive-Compulsive Disorder (OCD) and related disorders. Her NIH-, foundation-, and donor-funded mechanistic and clinical efficacy studies span targeted glutamatergic and opioid pathway pharmacotherapy, noninvasive brain stimulation, psychotherapy and suicide prevention. She is co-author of “Hoarding Disorder: A Comprehensive Clinical Guide,” published August 2022 by APA Publishing.
Dr. Rodriguez also serves as Deputy Editor of The American Journal of Psychiatry, member of the Research Council of the American Psychiatric Association, member of Brain & Behavior Research Foundation Scientific Council, member of the American Foundation for Suicide Prevention Advisory Group, and Scientific and Clinical Advisory Board member of the International OCD Foundation. She has won several national awards, including the Presidential Early Career Award for Scientists and Engineers (PECASE). The PECASE recognizes investigators who are pursuing bold and innovative projects and is considered one of the highest honors in scientific research. Carolyn presented her research at the World Economic Forum in Davos and Fortune Brainstorm Health 2022 and her work has been highlighted by organizations including NPR, PBS, New York Times, ABC News, NBC News, Newsweek, Fortune, and Time.com. She contributes articles to Harvard Business Review and Huffington Post to share scientific findings with the public.
Carolyn received her B.S. in Computer Science from Harvard University, followed by an M.D. from Harvard Medical School-M.I.T. and a Ph.D. in Neuroscience and Genetics from Harvard Medical School. Born in San Juan, Puerto Rico, she now lives with her husband and three children in Palo Alto. -
Fatima Rodriguez
Associate Professor of Medicine (Cardiovascular Medicine)
BioFatima Rodriguez, MD, MPH is an Associate Professor in Cardiovascular Medicine and (by courtesy) the Stanford Prevention Research Center. Dr. Rodriguez earned her medical degree from Harvard Medical School and her MPH from the Harvard School of Public Health. She then completed internal medicine residency at Brigham and Women’s Hospital and fellowship in cardiovascular medicine at Stanford University. She currently serves as the Section Chief of Preventive Cardiology. Dr. Rodriguez specializes in cardiovascular disease prevention, inherited lipid disorders, and cardiovascular risk assessment in high-risk populations.
Dr. Rodriguez’s research includes a range of topics around racial, ethnic, and gender disparities in cardiovascular disease prevention, developing novel interventions to address disparities, and opportunistic screening of coronary artery disease. -
Kacper Rogala
Assistant Professor of Structural Biology and of Chemical and Systems Biology
Current Research and Scholarly InterestsOur team is fascinated by how cells make growth decisions — to grow or not to grow. In order to grow, cells require nutrients, and we are unraveling how cells use specialized protein sensors and transporters to sense and traffic nutrients in between various compartments. We use approaches from structural biology, chemical biology, biophysics, biochemistry, and cell biology — to reveal the mechanisms of basic biological processes, and we develop chemical probes that modulate them.
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Angela Rogers
Associate Professor of Medicine (Pulmonary and Critical Care)
Current Research and Scholarly InterestsWe use genetics and genomics methodologies to identify novel ARDS pathobiology; we hope that this will enable identification of novel biomarkers, phenotypes, and treatments for the disease. We are building a plasma biobank of critically ill patients at Stanford, with a particular focus on metabolic changes in critical illness.
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Rajat Rohatgi
Professor of Biochemistry and of Medicine (Oncology)
Current Research and Scholarly Intereststhe overall goal of my laboratory is to uncover new regulatory mechanisms in signaling systems, to understand how these mechanisms are damaged in disease states, and to devise new strategies to repair their function.
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Maria Grazia Roncarolo
George D. Smith Professor of Stem Cell and Regenerative Medicine and Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy)
Current Research and Scholarly InterestsResearch Interests
Immunetolerance: Mechanisms underlying T-cell tolerance, induction of T-cell anergy and regulatory T cells; Immunomodulation: mAbs, proteins and low molecular weight compounds which can modulate T-cell activation; Primary immunodeficiencies: Characterization of molecular and immunological defects; Gene therapy: Gene transduction of hematopoietic cells for gene therapy in primary immunodeficiencies and metabolic diseases; Hematopoiesis: Mechanisms underlying growth and differentiation of hematopoietic stem cells; Transplantation: Immune reconstitution and T-cell tolerance after allogenic stem cell transplantation; Cytokines/Cytokine receptors: Role in regulation of immune and inflammatory responses
Clinical Interests
Primary Immunodeficiencies
Monogenic Autoimmune Disorders
Allogenic Bone Marrow Transplantation
Gene Therapy Clinical Trials
Cell Therapy Clinical Trials
Clinical Trials in Autoimmune Diseases and Organ Transplantation
Clinical Trials in Hemoglobinopathies -
Lisa Goldman Rosas
Assistant Professor (Research) of Epidemiology and Population Health and of Medicine (Primary Care and Population Health) and, by courtesy, of Pediatrics
BioLisa Goldman Rosas, PhD MPH is an Assistant Professor in the Department of Epidemiology and Population Health and the Department of Medicine, Division of Primary Care and Population Health at Stanford School of Medicine. An epidemiologist by training, Dr. Goldman Rosas’ research focuses on addressing disparities in chronic diseases such as diabetes, heart disease, depression, and cancer among racial/ethnic minority families. This research features rigorous quantitative and qualitative methodologies, participatory qualitative approaches, and shared leadership with patient and community partners. She is passionate about integrating patients, caregivers, community organizations, and other key stakeholders in the research process in order to affect the greatest improvements in health and well-being. As a reflection of this passion, Dr. Goldman Rosas serves as the Faculty Director for the School of Medicine Office of Community Engagement, Co-Director of Community-Engaged Research for the Office of Cancer Health Equity, and Director of the Outreach, Recruitment and Engagement Core for the Alzheimer's Disease Research Center. In these roles, she supports other faculty and patient and community partners to develop sustainable and meaningful partnerships to support transformative research. In addition to research, she teaches at the undergraduate and graduate levels and has a special focus on increasing diversity in biomedical research.
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Jessica Rose
Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsDr. Rose's research investigates neuromuscular mechanisms underlying cerebral palsy (CP) early brain and motor development in preterm children and . Research examines neonatal microstructural brain development on DTI and physiological correlates of motor function in preterm children. Dr. Rose served on the NIH Taskforce on Childhood Motor Disorders, the AACPDM Research Committee and Steering Committee to develop CDE for CP neuroimaging diagnostics, and serves on the Board of Directors of SBMT.
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Glenn Rosen
Associate Professor of Medicine (Pulmonary and Critical Care Medicine), Emeritus
Current Research and Scholarly InterestsOur laboratory examines apoptotic and cell signaling pathways in cancer and lung disease. We are studying signaling pathways that regulate oxidative stress responses and cancer cell growth. Part of these studies focus on analysis of non-canonical transcription regulatory functions of the TERC and Tert components of telomerase in lung disease and cancer.
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Michael J Rosen, MD, MSCI
Stanford University Endowed Professor for Pediatric IBD and Celiac Disease
BioI am a pediatric gastroenterologist and physician scientist, who has been devoted to inflammatory bowel disease (IBD) research since beginning medical training over 20 years ago. I am also Director of the Stanford Center for Pediatric IBD and Celiac Disease. I have expertise crossing mucosal immunology and epithelial biology, formal training and experience in clinical and translational investigation with human biospecimens, and direct insight regarding the important clinical challenges caring for children with complicated IBD. My translational research program focuses on how the immune system regulates epithelial function in chronic intestinal inflammation as it relates to IBD. My clinical research program has focused on optimization of anti-TNF therapy in pediatric IBD, and in particular acute severe ulcerative colitis (ASUC). My laboratory has demonstrated a protective role for IL33, a cytokine that induces type 2 cytokines from T cells an innate lymphoid cells (ILCs), in acute oxazolone colitis through preservation of epithelial goblet cells and barrier function. In line with this finding, we have also shown in a large prospective patient cohort that mucosal expression of type 2 and type 17 immune response genes distinguishes ulcerative colitis (UC) from colon-only Crohn’s disease, and that type 2 gene expression is associated with superior clinical outcome in pediatric UC. We have now developed an organoid-immune cell in vitro culture system to demonstrate the ILC2-dependent mechanism through which IL33 induces goblet cell differentiation in the intestinal epithelium. I led the multicenter study Anti-TNF for Refractory Colitis in Hospitalized Children (ARCH) Study, which aims to establish determinants of anti-TNF response in pediatric ASUC and currently Co-Chair the Crohn's & Colitis Foundations Cohort for Pediatric Translational and Clinical Research in IBD (CAPTURE IBD) and PRO-KIIDS Pediatric IBD clinical research network.
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Noah Rosenberg
Stanford Professor of Population Genetics and Society
Current Research and Scholarly InterestsHuman evolutionary genetics, mathematical models in evolution and genetics, mathematical phylogenetics, statistical and computational genetics, theoretical population genetics
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David Rosenthal
Professor of Pediatrics (Pediatric Cardiology)
Current Research and Scholarly InterestsResearch interests include the study of Heart Failure, Cardiomyopathy and ventricular dysfunction in children, from a clinical perspective. Investigations include clinical trials of medications, cardiac resynchronization, and mechanical circulatory support.
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Stephen J. Roth
Professor of Pediatrics (Cardiology)
Current Research and Scholarly InterestsRandomized Therapeutic Trials in Pediatric Heart Disease, NIH/U01 GrantNo. HL68285 2001-2006.
Heparin and the Reduction of Thrombosis (HART) Study. Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006.
A Pilot Trial fo B-type Natriuretic Peptide for Promotion of Urine Output in Diuretic-Resistant Infants Following Cardiovascular Surgery.Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006. -
Grant M. Rotskoff
Assistant Professor of Chemistry
BioGrant Rotskoff studies the nonequilibrium dynamics of living matter with a particular focus on self-organization from the molecular to the cellular scale. His work involves developing theoretical and computational tools that can probe and predict the properties of physical systems driven away from equilibrium. Recently, he has focused on characterizing and designing physically accurate machine learning techniques for biophysical modeling. Prior to his current position, Grant was a James S. McDonnell Fellow working at the Courant Institute of Mathematical Sciences at New York University. He completed his Ph.D. at the University of California, Berkeley in the Biophysics graduate group supported by an NSF Graduate Research Fellowship. His thesis, which was advised by Phillip Geissler and Gavin Crooks, developed theoretical tools for understanding nonequilibrium control of the small, fluctuating systems, such as those encountered in molecular biophysics. He also worked on coarsegrained models of the hydrophobic effect and self-assembly. Grant received an S.B. in Mathematics from the University of Chicago, where he became interested in biophysics as an undergraduate while working on free energy methods for large-scale molecular dynamics simulations.
Research Summary
My research focuses on theoretical and computational approaches to "mesoscale" biophysics. Many of the cellular phenomena that we consider the hallmarks of living systems occur at the scale of hundreds or thousands of proteins. Processes like the self-assembly of organelle-sized structures, the dynamics of cell division, and the transduction of signals from the environment to the machinery of the cell are not macroscopic phenomena—they are the result of a fluctuating, nonequilibrium dynamics. Experimentally probing mesoscale systems remains extremely difficult, though it is continuing to benefit from advances in cryo-electron microscopy and super-resolution imaging, among many other techniques. Predictive and explanatory models that resolve the essential physics at these intermediate scales have the power to both aid and enrich the understanding we are presently deriving from these experimental developments.
Major parts of my research include:
1. Dynamics of mesoscale biophysical assembly and response.— Biophysical processes involve chemical gradients and time-dependent external signals. These inherently nonequilibrium stimuli drive supermolecular organization within the cell. We develop models of active assembly processes and protein-membrane interactions as a foundation for the broad goal of characterizing the properties of nonequilibrium biomaterials.
2. Machine learning and dimensionality reduction for physical models.— Machine learning techniques are rapidly becoming a central statistical tool in all domains of scientific research. We apply machine learning techniques to sampling problems that arise in computational chemistry and develop approaches for systematically coarse-graining physical models. Recently, we have also been exploring reinforcement learning in the context of nonequilibrium control problems.
3. Methods for nonequilibrium simulation, optimization, and control.— We lack well-established theoretical frameworks for describing nonequilibrium states, even seemingly simple situations in which there are chemical or thermal gradients. Additionally, there are limited tools for predicting the response of nonequilibrium systems to external perturbations, even when the perturbations are small. Both of these problems pose key technical challenges for a theory of active biomaterials. We work on optimal control, nonequilibrium statistical mechanics, and simulation methodology, with a particular interest in developing techniques for importance sampling configurations from nonequilibrium ensembles. -
Daniel Rubin
Professor of Biomedical Data Science, of Radiology (Integrative Biomedical Imaging Informatics at Stanford), of Medicine (Biomedical Informatics Research) and, by courtesy, of Ophthalmology
Current Research and Scholarly InterestsMy research interest is imaging informatics--ways computers can work with images to leverage their rich information content and to help physicians use images to guide personalized care. Work in our lab thus lies at the intersection of biomedical informatics and imaging science.
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Mirabela Rusu
Assistant Professor of Radiology (Integrative Biomedical Imaging Informatics) and, by courtesy, of Urology and of Biomedical Data Science
Current Research and Scholarly InterestsDr. Mirabela Rusu focuses on developing analytic methods for biomedical data integration, with a particular interest in radiology-pathology fusion. Such integrative methods may be applied to create comprehensive multi-scale representations of biomedical processes and pathological conditions, thus enabling their in-depth characterization.
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Florentine Rutaganira
Assistant Professor of Biochemistry and of Developmental Biology
BioDr. Rutaganira uses choanoflagellates—the closest living single-celled relatives to animals—to study the origin of animal cell communication. Dr. Rutaganira applies chemical, genetic, and cell biological tools to probe choanoflagellate cell-cell communication, with implications for understanding not only animal cell signaling, but also the origin of multicellularity in animals.
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Brian Rutt
Professor of Radiology (Radiological Sciences Lab), Emeritus
Current Research and Scholarly InterestsMy research interests center on MRI research, including high-field and high-resolution MRI technology development as well as applications of advanced MRI techniques to studying the brain, cardiovascular system and cancer.
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Raya Saab
Lindhard Family Professor of Pediatric Cancer Biology
BioOur laboratory focuses on investigating molecular mechanisms of oncogene-induced tumorigenesis and tumor suppressor pathways, and oncogenic signaling in the pediatric solid tumor rhabdomyosarcoma. Our earlier work identified the tumor suppressors p53 and p18Ink4c as inhibitors of Cyclin D1-driven tumorigenesis in a pineoblastoma model, through senescence induction, and highlighted distinct roles for the the RB and p53 pathways in induction and maintenance of oncogene-induced senescence. We also identified CDK2 as a potential target for inducing senescence in premalignant lesions to inhibit tumor progression.
Our current focus is on studying oncogenic signaling and tumor suppression in the childhood tumor rhabdomyosarcoma, to identify key mediators of invasion and metastasis, which is the most common cause of treatment failure clinically. We use preclinical in vitro and in vivo models, including murine and human cell lines, and mouse models of disease.
We have recently uncovered a paracrine role for rhabdomyosarcoma-secreted exosomes in impacting biology of stromal cells. Rhabdomyosarcoma-derived exosomes carry specific miRNA cargo that imparts an invasive and migratory phenotype on normal recipient fibroblasts, and proteomic analysis revealed specific and unique pathways relevant to the two different molecular rhabdomyosarcoma subtypes that are driven by distinct oncogenic pathways. We identified that the driver oncogene in fusion-positive rhabdomyosarcoma, PAX3-FOXO1, modulates exosome cargo to promote invasion, migration, and angiogenic properties, and identified specific microRNA and protein cargo acting as effectors of PAX3-FOXO1 exosome-mediated signaling, including modulation of oxidative stress response and cell survival signaling.
Our ongoing work is focused on interrogating specific paracrine signaling pathways and molecular mechanisms of metastatic disease progression in rhabdomyosarcoma, for potential therapeutic targeting. -
Chiara Sabatti
Professor of Biomedical Data Science and of Statistics
Current Research and Scholarly InterestsStatistical models and reasoning are key to our understanding of the genetic basis of human traits. Modern high-throughput technology presents us with new opportunities and challenges. We develop statistical approaches for high dimensional data in the attempt of improving our understanding of the molecular basis of health related traits.
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Amin Saberi
Professor of Management Science and Engineering
BioAmin Saberi is Professor of Management Science and Engineering at Stanford University. He received his B.Sc. from Sharif University of Technology and his Ph.D. from Georgia Institute of Technology in Computer Science. His research interests include algorithms, design and analysis of social networks, and applications. He is a recipient of the Terman Fellowship, Alfred Sloan Fellowship and several best paper awards.
Amin was the founding CEO and chairman of NovoEd Inc., a social learning environment designed in his research lab and used by universities such as Stanford as well as non-profit and for-profit institutions for offering courses to hundreds of thousands of learners around the world. -
Debra Safer
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult)
Current Research and Scholarly InterestsPrimary research interests include the nature and treatment of eating disorders
(particularly bulimia nervosa and binge eating disorder), the development and treatment of obesity, and the development and treatment of problematic eating patterns in patients following bariatric surgery. -
Marc R. Safran, MD
Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsDr. Safrans practice focuses on arthroscopic management of hip problems as well as articular cartilage regeneration, shoulder surgery and athletic shoulder and elbow problems. He is actively involved in research in these areas.
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Julien Sage
Elaine and John Chambers Professor of Pediatric Cancer and Professor of Genetics
Current Research and Scholarly InterestsWe investigate the mechanisms by which normal cells become tumor cells, and we combine genetics, genomics, and proteomics approaches to investigate the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells and to identify novel therapeutic targets in cancer cells.
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Manish Saggar
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly InterestsWe are a computational neuropsychiatry lab dedicated to developing computational methods to better understand brain’s overall dynamical organization in healthy and patient populations. We employ algorithms from a wide range of fields, including Applied Mathematics, Econometrics, Machine Learning, Biophysics, and Network Science.
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Kathleen M. Sakamoto
Shelagh Galligan Professor in the School of Medicine
Current Research and Scholarly InterestsMy research focuses on the molecular pathways that regulate normal and aberrant blood cell development, including acute leukemia and bone marrow failure syndromes. We are also studying novel drugs for treatment of cancer.
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Michael Salerno
Professor of Medicine (Cardiovascular) and of Radiology (Cardiovascular Imaging)
BioDr. Salerno completed his BS in Biological Engineering at Cornell University, and his MD and PhD in Biomedical Engineering at the University of Virginia as part of the Medical Scientist Training Program. He then completed the American Board of Internal Medicine Research Pathway with an Internal Medicine residency at Stanford University, and his general cardiology fellowship at Duke University Medical Center. During his time at Duke he completed a dedicated year in cardiovascular MRI at the Duke Cardiovascular MR Imaging Center. He returned to UVA in 2008 to complete a 2-year advanced cardiovascular imaging fellowship where he trained in CMR and cardiovascular CTA. He achieved COCATS Level III training in all cardiovascular imaging modalities (Echo, Nuclear, CMR, CCT), and is board certified in Echocardiography and Nuclear Cardiology. He served as faculty at UVA in Cardiology, Radiology, and Biomedical Engineering from 2010-2021 where he was the Director of Cardiac MRI and the Medical Director of Echocardiography, before returning to Stanford.
His research involves the development and evaluation of novel MRI pulse sequences and techniques to improve the clinical utility of CMR imaging. The current focus of the research is on quantitative myocardial perfusion imaging, quantitative imaging of myocardial fibrosis, rapid free-breathing and self-gated imaging, and deep learning for image reconstruction and post-processing. His laboratory includes undergraduate and graduate engineering students as well as clinical cardiovascular imaging fellows to bring new advances into clinical practice. Dr. Salerno has been in the field of MRI for 25 years and holds multiple patents related to the development and application of novel pulse sequences for MRI. He has received numerous research awards, and has published extensively in the areas of MRI, cardiovascular MRI and multi-modality cardiovascular imaging. His research has been supported by the AHA and the National Institutes of health. He is a deputy editor for JACC Cardiovascular Imaging.
Outside of work, Dr. Salerno enjoys sailing, rock climbing, skiing, running, biking, hiking, and spending time with his wife Cherie, and his two boys Christopher and Joseph. -
J Kenneth Salisbury, Jr.
Professor (Research) of Computer Science and of Surgery (Anatomy), Emeritus
BioSalisbury worked on the development of the Stanford-JPL Robot Hand, the JPL Force Reflecting Hand Controller, the MIT-WAM arm, and the Black Falcon Surgical Robot. His work with haptic interface technology led to the founding of SensAble Technology, producers of the PHANToM haptic interface and software. He also worked on the development of telerobotic systems for dexterity enhancement in the operating room. His current research focuses on human-machine interaction, cooperative haptics, medical robotics, and surgical simulation.
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Alberto Salleo
Hong Seh and Vivian W. M. Lim Professor
Current Research and Scholarly InterestsNovel materials and processing techniques for large-area and flexible electronic/photonic devices. Polymeric materials for electronics, bioelectronics, and biosensors. Electrochemical devices for neuromorphic computing. Defects and structure/property studies of polymeric semiconductors, nano-structured and amorphous materials in thin films. Advanced characterization techniques for soft matter.
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Julia Salzman
Associate Professor of Biomedical Data Science, of Biochemistry and, by courtesy, of Statistics and of Biology
Current Research and Scholarly Interestsstatistical computational biology focusing on splicing, cancer and microbes
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Peter L. Santa Maria, MBBS, PhD
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Bioengineering
On Partial Leave from 08/01/2023 To 07/14/2024Current Research and Scholarly InterestsWe study chronic suppurative otitis media, a chronic biofilm infection of the middle ear predominantly involving pseudomonas and staph aureus. We are investigating mechanisms of sensory hearing loss, host microbe interactions and trialling novel therapeutics.
Our work in tympanic membrane regeneration has entered clinical trials.
Novel treatments for wound healing in intra oral wounds with potential applications to prevent post tonsillectomy wound healing and oral mucositis. -
Juan G. Santiago
Charles Lee Powell Foundation Professor
Current Research and Scholarly Interestshttp://microfluidics.stanford.edu/Projects/Projects.html
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Serena Sanulli
Assistant Professor of Genetics
Current Research and Scholarly InterestsWe study the organizing principles of the genome and how these principles regulate cell identity and developmental switches. We combine Biochemistry and Biophysical methods such as NMR and Hydrogen-Deuterium Exchange-MS with Cell Biology, and Genetics to explore genome organization across length and time scales and understand how cells leverage the diverse biophysical properties of chromatin to regulate genome function.
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Robert Sapolsky
John A. and Cynthia Fry Gunn Professor, Professor of Biology, of Neurology and of Neurosurgery
Current Research and Scholarly InterestsNeuron death, stress, gene therapy
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Kavita Sarin, MD, PhD
Associate Professor of Dermatology
Current Research and Scholarly InterestsMy research encompasses two main areas: 1) Using next-generation RNA, whole genome, and exome sequencing, we are investigating the genetic alterations involved in skin cancer progression, response to therapy, and other clinical outcomes and 2) We are developing and implementing genome-wide genetic risk prediction assessments for skin cancer into clinical use and studying the impact of this information on patient care.
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Peter Sarnow
Burt and Marion Avery Professor of Immunology
Current Research and Scholarly InterestsOur laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.
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Ansuman Satpathy
Assistant Professor of Pathology
Current Research and Scholarly InterestsOur lab works at the interface of immunology, cancer biology, and genomics to study cellular and molecular mechanisms of the immune response to cancer. In particular, we are leveraging high-throughput genomic technologies to understand the dynamics of the tumor-specific T cell response to cancer antigens and immunotherapies (checkpoint blockade, CAR-T cells, and others). We are also interested in understanding the impact of immuno-editing on the heterogeneity and clonal evolution of cancer.
We previously developed genome sequencing technologies that enable epigenetic studies in primary human immune cells from patients: 1) 3D enhancer-promoter interaction profiling (Nat Genet, 2017), 2) paired epigenome and T cell receptor (TCR) profiling in single cells (Nat Med, 2018), 3) paired epigenome and CRISPR profiling in single cells (Cell, 2019), and high-throughput single-cell ATAC-seq in droplets (Nature Biotech, 2019). We used these tools to study fundamental principles of the T cell response to cancer immunotherapy (PD-1 blockade) directly in cancer patient samples (Nature Biotech, 2019; Nat Med, 2019). -
Elizabeth Sattely
Associate Professor of Chemical Engineering
BioPlants have an extraordinary capacity to harvest atmospheric CO2 and sunlight for the production of energy-rich biopolymers, clinically used drugs, and other biologically active small molecules. The metabolic pathways that produce these compounds are key to developing sustainable biofuel feedstocks, protecting crops from pathogens, and discovering new natural-product based therapeutics for human disease. These applications motivate us to find new ways to elucidate and engineer plant metabolism. We use a multidisciplinary approach combining chemistry, enzymology, genetics, and metabolomics to tackle problems that include new methods for delignification of lignocellulosic biomass and the engineering of plant antibiotic biosynthesis.
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Alan F. Schatzberg
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsBiological bases of depressive disorders;, glucocorticoid/dopamine interactions in delusional depression;, pharmacologic treatment of depressive disorders.
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David Schneider
Professor of Microbiology and Immunology
On Partial Leave from 03/24/2024 To 10/23/2024Current Research and Scholarly InterestsWe study innate immunity and microbial pathogenesis. We have been studying models for a variety of bacterial infections including: Listeria, Mycobacteria, Salmonella and Streptococcus as well as some fungi, malaria and viruses. Our current focus is to determine how we recover from infections.
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Mark J. Schnitzer
Professor of Biology, of Applied Physics and of Neurosurgery (Adult Neurosurgery)
Current Research and Scholarly InterestsThe goal of our research is to advance experimental paradigms for understanding normal cognitive and disease processes at the level of neural circuits, with emphasis on learning and memory processes. To advance these paradigms, we invent optical brain imaging techniques, several of which have been widely adopted. Our neuroscience studies combine these imaging innovations with behavioral, electrophysiological, optogenetic and computational methods, enabling a holistic approach to brain science.
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Birgitt Schuele
Associate Professor (Research) of Pathology
BioBirgitt Schüle, MD, is an Associate Professor in the Department of Pathology at Stanford University School of Medicine. Her research focuses on medical genetics and stem cell modeling to uncover disease mechanisms and pathways involved in neurodegeneration in Parkinson's disease and related disorders. She is dedicated to developing novel therapeutic strategies that contribute to the advancement of precision medicine.
Dr. Schüle obtained her medical training from the Georg-August University Göttingen and Medical University Lübeck, Germany, between 1993 and 2001. She earned her doctoral degree in medicine (Dr. med.) in neurophysiology from the Georg-August University Göttingen in 2001. During her neurology internship from 2001 to 2002 at the Medical University of Lübeck under the guidance of Prof. Christine Klein. Subsequently, she pursued a postdoctoral fellowship in human genetics with Prof. Uta Francke at Stanford University School of Medicine from 2003 to 2005.
From 2005 to 2019, Dr. Schüle demonstrated leadership in spearheading critical clinical research programs and establishing essential biospecimen repositories for neurogenetics, translational stem cell research, and brain donation at the Parkinson's Institute and Clinical Center.
Currently, Dr. Schüle serves as the Associate Core Leader, Neuropathology, within the Stanford Alzheimer Research Center (ADRC). Her contributions to ADRC include genetic characterization, biobanking, and the establishment of a human induced pluripotent stem cell and post-mortem leptomeninges tissue bank. These resources are shared with the data and tissue repositories at the National Institutes of Health (NIH), facilitating collaborative research and advancing our understanding of neurodegenerative diseases.
Dr. Schüle's expertise and dedication in the field of neurodegeneration contribute significantly to the advancement of medical knowledge. She is recognized as a respected member of the scientific community, playing an important role in the pursuit of effective treatments and precision medicine approaches. -
Kevin Schulman
Professor of Medicine (Hospital Medicine), by courtesy, of Health Policy and of Operations, Information and Technology at the Graduate School of Business
BioDr. Schulman is a Professor of Medicine, Clinical Excellence Research Center (CERC) at the Stanford University School of Medicine, and, by courtesy, Professor of Operations, Information and Technology at Stanford’s Graduate School of Business. He is the Faculty Director of Stanford’s new applied master's degree program, the Master of Science in Clinical Informatics Management program.
Dr. Schulman is a health economist/health services researcher working at the intersection of business, medicine and technology. With over 500 publications, he has had a broad impact on several areas of health policy (Scopus h-index=81). His research has appeared in the New England Journal of Medicine, the Journal of the American Medical Association, and Health Affairs. He is the editor-in-chief of Health Management, Policy and Innovation (www.HMPI.Org), and Senior Associate Editor of Health Service Research (HSR).
He is a graduate of Dartmouth College, the New York University School of Medicine, and The Wharton Health Care Management Program. -
Molly Schumer
Assistant Professor of Biology
BioMolly Schumer is an Assistant Professor in Biology. She is interested in genetics and evolutionary biology. After receiving her PhD at Princeton, she did her postdoctoral work at Columbia and was a Junior Fellow in the Harvard Society of Fellows and Hanna H. Gray Fellow at Harvard Medical School. Current research in the lab centers on understanding the genetic mechanisms of evolution, with a focus on natural populations.
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Daniel Schwartz
Dean of the Graduate School of Education and the Nomellini & Olivier Professor of Educational Technology
Current Research and Scholarly InterestsInstructional methods, transfer of learning and assessment, mathematical development, teachable agents, cognition, and cognitive neuroscience.
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Matthew P. Scott
Professor of Developmental Biology, Emeritus
Current Research and Scholarly InterestsOur research has been focused on the genetic regulation of animal development and its relation to birth defects, cancer, and neurodegeneration. We studied mechanisms and functions of Hedgehog (Hh) signaling, which controls cell fates and growth, in the context of normal development and brain cancer. We studied a neurodegenerative disease, Niemann-Pick C syndrome, that affects intracellular organelle movements and sterol homeostasis. Due to Dr. Scott's new job, the lab is no longer active.
