School of Medicine
Showing 151-200 of 633 Results
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Walter Park
Associate Professor of Medicine (Gastroenterology and Hepatology)
Current Research and Scholarly InterestsDr. Park's research interests are in the diagnosis and management of pancreatic cysts, acute and chronic pancreatitis. His approach incorporates methods in health services research including the use of observational datasets, cost-effectiveness studies, and the development of clinical cohorts.
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Karen J. Parker, PhD
Truong-Tan Broadcom Endowed Professor and Professor, by courtesy, of Comparative Medicine
Current Research and Scholarly InterestsThe Parker Lab conducts research on the biology of social functioning in monkeys, typically developing humans, and patients with social impairments.
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Robertson Parkman
Adjunct Professor, Pediatrics - Stem Cell Transplantation
BioMy principal research interests have been the assessment of the immunological consequences of hematopoietic stem cell transplantation including both acute and chronic graft versus host disease and immune reconstitution and the use of hematopoietic stem cell transplantation to treat genetic diseases. My laboratory was the first to suggest that chronic graft versus host disease was an autoimmune disease directed at histocompatibility antigens shared by donors and recipients. The observation leaded to the assessment of the role of thymic dysfunction in the pathogenesis of chronic graft versus host disease. As a pediatric immunologist I have investigated the role of hematopoietic stem cell transplantation initially in the treatment of primary immune deficiency diseases and later the treatment of metabolic diseases, which lead to my involvement in the early gene transfer clinical trials.
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Ugur Parlatan
Basic Life Research Scientist, Rad/Canary Center at Stanford for Cancer Early Detection
BioDr. Ugur Parlatan, PhD in physics, specializes in optics with a focus on its medical applications, particularly in characterizing extracellular vesicles through molecular fingerprinting. His research aims to advance optical techniques for improved disease diagnostics.
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Jane Parnes
Professor of Medicine, Emerita
Current Research and Scholarly InterestsThe lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity. B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor. We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance. We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease.
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Julie Parsonnet
George DeForest Barnett Professor of Medicine and Professor of Epidemiology and Population Health
Current Research and Scholarly InterestsI am an infectious diseases epidemiologist who has done large field studies in both the US and developing countries. We research the long-term consequences of chronic interactions between the human host and the microbial world. My lab has done fundamental work establishing the role of H. pylori in causing disease and understanding its epidemiology. Currently, our research dissects how and when children first encounter microbes and the long term effects of these exposures on health.
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Sonia Partap
Clinical Professor, Neurology
Clinical Professor (By courtesy), Neurosurgery
Clinical Professor, PediatricsCurrent Research and Scholarly InterestsMy research interests involve the epidemiology, treatment and diagnosis of pediatric and young adult brain tumors. I am also interested in long-term neurologic effects and designing clinical trials to treat brain and spinal cord tumors.
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Josef Parvizi, MD, PhD
Professor of Neurology (Adult Neurology) and, by courtesy, of Neurosurgery
BioDr. Parvizi completed his medical internship at Mayo Clinic, neurology training at Harvard, and subspecialty training in clinical neurophysiology and epilepsy at UCLA before joining the Department of Neurology and Neurological Sciences at Stanford in 2007. Dr. Parvizi directs the Stanford Program for Medication Resistant Epilepsies and specializes in surgical treatments of intractable focal epilepsies. Dr. Parvizi is the principal investigator in the Laboratory of Behavioral and Cognitive Neuroscience, where he leads a team of investigators to study the human brain. http://med.stanford.edu/parvizi-lab.html.
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Anca M. Pasca, MD
Assistant Professor of Pediatrics
Current Research and Scholarly InterestsThe research focus of the lab is to understand molecular mechanisms underlying neurodevelopmental disorders associated with premature birth, neonatal and fetal brain injury with the long-term goal of translating the lab’s findings into therapeutics. The research team employs a multidisciplinary approach involving genetics, molecular and developmental neurobiology, animal models and neural cells differentiated from patient-derived induced pluripotent stem (iPS) cells. In particular, the lab is using a powerful 3D human brain-region specific organoid system developed at Stanford (Nature Methods, 2015; Nature Protocols, 2018) to ask questions about brain injury during development.
https://www.neopascalab.org/ -
Sergiu P. Pasca
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences and Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program
Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
To address this, we are developing bottom-up approaches to generate and assemble, from multi-cellular components, human neural circuits in vitro and in vivo.
We introduced the use of instructive signals for deriving from human pluripotent stem cells self-organizing 3D cellular structures named brain region-specific spheroids/organoids. We demonstrated that these cultures, such as the ones resembling the cerebral cortex, can be reliably derived across many lines and experiments, contain synaptically connected neurons and non-reactive astrocytes, and can be used to gain mechanistic insights into genetic and environmental brain disorders. Moreover, when maintained as long-term cultures, they recapitulate an intrinsic program of maturation that progresses towards postnatal stages.
We also pioneered a modular system to integrate 3D brain region-specific organoids and study human neuronal migration and neural circuit formation in functional preparations that we named assembloids. We have actively applied these models in combination with studies in long-term ex vivo brain preparations to acquire a deeper understanding of human physiology, evolution and disease mechanisms.
We have carved a unique research program that combines rigorous in vivo and in vitro neuroscience, stem cell and molecular biology approaches to construct and deconstruct previously inaccessible stages of human brain development and function in health and disease.
We believe science is a community effort, and accordingly, we have been advancing the field by broadly and openly sharing our technologies with numerous laboratories around the world and organizing the primary research conference and the training courses in the area of cellular models of the human brain. -
Magdalini Paschali
Postdoctoral Scholar, Radiology
Current Research and Scholarly InterestsMy research focuses on utilizing machine learning models to enhance the understanding, diagnosis, and treatment of clinical disorders. I am interested in multi-modal learning, combining imaging data like MRI and CT scans with non-imaging data such as electronic health records, creating more holistic and accurate diagnostic models. I am also interested in the robustness of deep neural networks under domain shifts, investigating how models perform when faced with changes in input data distributions.
Finally, I am interested in early biomarker identification using AI model interpretability, to enable the early detection and targeted treatment of chronic disorders. -
Ryan Pate, MD, MS
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioDr. Ryan Pate is a board-certified adult psychiatrist with eligibility for board certification in geriatric psychiatry. He completed his general adult psychiatry training at Dartmouth-Hitchcock and pursued his geriatric psychiatry fellowship at Stanford Health Care. In addition to his psychiatry training, he is actively participating in the psychoanalytical psychotherapy fellowship offered by the Palo Alto division of the San Francisco Center for Psychoanalysis. Dr. Pate's research interests primarily focus on providing support for caregivers and developing group interventions tailored to older adults with mental health disorders. At Stanford, his professional practice primarily takes place in an outpatient setting, where he conducts appointments that involve a combination of medication management and psychotherapy interventions. Beyond his clinical work, Dr. Pate is dedicated to medical education.
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Alok Patel
Clinical Assistant Professor, Pediatrics
BioAlok Patel is a pediatric hospitalist, medical journalist, on-camera expert, producer, and devotee of creative, engaging science communication tactics. He currently serves as the Faculty Director of Communications for the Department of Pediatrics. Through this role, he helps coordinate creative media strategies for awareness, education, advocacy, recruitment and more.
Dr. Patel has extensive experience in broadcast journalism, on-camera work, script writing, podcast hosting, media consulting, and designing social media campaigns and hopes to lend these skills to his work in public health messaging. He currently works as a pediatric hospitalist within the department of pediatrics at Lucile Packard Children's Hospital. -
Anisha I Patel
Professor of Pediatrics (General Pediatrics) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsDr. Patel's research interests focus on reducing socioeconomic disparities in chronic diseases, including childhood obesity. Over the past 10 years, Dr. Patel has led numerous studies to encourage healthy beverage intake among children and adolescents. These studies include analyses of large national data sets, conduct of randomized controlled trials in schools, child care, and community settings to examine how interventions to increase children’s intake of water instead of sugar-sweetened beverages impact child health, and the evaluation of policy efforts to improve the healthfulness of beverages offered in schools and community settings.
Dr. Patel has a diverse funding portfolio ranging from the Robert Wood Johnson Foundation Healthy Eating Research Program, the W.K. Kellogg Foundation, and the National Institutes of Health. Dr. Patel has presented her research to local, national and international audiences. She has also been recognized for her research with awards from the American Academy of Pediatrics and the University of North Carolina, Chapel Hill School of Public Health.