School of Medicine
Showing 1-50 of 8,576 Results
Ronald W. Davis
Professor of Biochemistry and of Genetics
Current Research and Scholarly InterestsWe are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.
Christos E. Constantinou
Associate Professor of Urology, Emeritus
Current Research and Scholarly InterestsMy main recent interest is the application of Biomedical Engineering approaches for the clinical visualization and characterization of the static and dynamic properties of pelvic floor function. This extends to ultrasound Imaging and image processing, construction of computer models and biomechanics analysis of pelvic floor function. It is envisioned that these considerations are important constituents of the clinical evaluation of patients with lower urinary tract dysfunction and urodynamics.
Lucy Becker Professor in Medicine, Emeritus
Current Research and Scholarly InterestsDefining the role of matrix metalloproteinases in connective tissue remodeling of the skin.Defining the macromolecular structures of the cutaneous basement membrane zone.Developing methods for delivery of extracutaneous gene therapy in epidermolysis bullosa.
Professor of Pediatrics (Endocrinology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly InterestsMy research interests cover a number of areas in Pediatric Endocrinology and Diabetes. I am PI of the Stanford Center for the NIH-funded Type-1 Diabetes TrialNet group. TrialNet conducts clinical trials directed at preventing or delaying the onset of Type 1 diabetes. I am an investigator in DirecNet, another NIH-funded study group, which is devoted to evaluating glucose sensors and the role of technology on the management of diabetes.
Professor of Biochemistry and, by courtesy, of Chemical Engineering and of Chemistry
Current Research and Scholarly InterestsOur research is aimed at understanding the chemical and physical behavior underlying biological macromolecules and systems, as these behaviors define the capabilities and limitations of biology. Toward this end we study folding and catalysis by RNA, as well as catalysis by protein enzymes.
Professor (Research) of Medicine (Oncology)
Current Research and Scholarly InterestsOur research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria.
Professor of Pediatrics (Critical Care) at the Lucile Salter Packard Children's Hospital at Stanford, Emeritus
Current Research and Scholarly Interests1) Collaborative efforts with Dale Umetsu and Dave Lewis in evaluating alveolar macrophage response to antigen. We try to examine cytokine activation and inhibition. I perform bronchoalveolar lavage in these patients in order to obtain alveolar macrophages which we culture, stimulate and study.
2) Evaluate outcomes for patients admitted to the Pediatric Intensive Care Unit from the EMS services for trauma and other life-threatening events.
Professor of Biochemistry and of Microbiology and Immunology
Current Research and Scholarly InterestsWe study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis.
Peter K. Jackson
Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Current Research and Scholarly InterestsCell cycle and cyclin control of DNA replication .
Klaus Bensch Professor in Pathology
Current Research and Scholarly InterestsOur interests include:
1) The physiology and significance of lymphocyte homing in local and systemic immunity;
2) biochemical and genetic studies of molecules that direct leukocyte recruitment;
3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines;
4) vascular differentiation in normal and pathologic inflammatory states;
5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs.
Associate Professor of Genetics and, by courtesy, of Ophthalmology
Current Research and Scholarly InterestsThe Vollrath lab works to uncover molecular mechanisms relevant to the health and pathology of the outer retina. We study the retinal pigment epithelium (RPE), a cell monolayer adjacent to photoreceptors that performs a variety of tasks crucial for retinal homeostasis. Specific areas of interest include the circadian regulation of RPE phagocytosis of photoreceptor outer segment tips, and how RPE metabolic dysfunction contributes to retinal degenerative diseases.
John A. Overdeck Professor, Professor of Statistics and of Biomedical Data Sciences
Current Research and Scholarly InterestsFlexible statistical modelling, datamining, bioinformatics, and statistical computing.
Donald Kennedy Chair in the School of Humanities and Sciences and Professor of Genetics
Current Research and Scholarly InterestsThe long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.
Lee Otterson Professor in the School of Engineering and Professor of Bioengineering, of Applied Physics and, by courtesy, of Physics
Current Research and Scholarly InterestsSingle molecule biophysics, precision force measurement, micro and nano fabrication with soft materials, integrated microfluidics and large scale biological automation.
Associate Professor of Radiology (Radiological Sciences Laboratory) and, by courtesy, of Electrical Engineering and of Bioengineering
Current Research and Scholarly InterestsI am interested in magnetic resonance imaging (MRI) applications including cardiovascular, abdominal, breast and musculoskeletal imaging. These applications require development of faster and more efficient MRI methods that provide improved diagnostic contrast compared with current methods. My work includes novel excitation schemes, efficient imaging methods and reconstruction tools. Please see my research site (above) for most up-to-date information.
Johnson & Johnson Professor of Surgery and Professor, by courtesy, of Bioengineering and of Materials Science and Engineering
Current Research and Scholarly InterestsGeoffrey Gurtner's Lab is interested in understanding the mecahnism of new blood vessel growth following injury and how pathways of tissue regeneration and fibrosis interact in wound healing.
Luis de Lecea
Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical and Translational Neurosciences Incubator)
Current Research and Scholarly InterestsMy lab uses molecular, optogenetic, anatomical and behavioral methods to identify and manipulate the neuronal circuits underlying brain arousal, with particular attention to sleep and wakefulness transitions. We are also interested in the changes that occur in neuronal circuits in conditions of hyperarousal such as stress and drug addiction.
Professor of Chemical and Systems Biology and of Developmental Biology
Current Research and Scholarly InterestsInteractions between the genome and its cellular and signaling environments, which ultimately occur at the level of chromatin, are the key to comprehending how cell-type-specific gene expression patterns arise and are maintained during development. Research in our laboratory is focused on understanding how information encoded by the genome is integrated with the transcriptional machinery and epigenetic regulation to allow for emergence of form and function during embryogenesis.
Associate Professor (Research) of Psychiatry and Behavioral Sciences (Sleep Medicine)
Current Research and Scholarly InterestsDr. Zeitzer is a circadian physiologist specializing in the understanding of the impact of light on circadian rhythms and other aspects of non-image forming light perception.
He examines the manner in which humans respond to light and ways to manipulate this responsiveness, with direct application ti jet lag, shift work, and altered sleep timing in teens. Dr. Zeitzer has also pioneered the use of actigraphy in the determination of epiphenomenal markers of psychiatric disorders.
Associate Professor of Materials Science and Engineering and of Photon Science
BioMelosh's research is focused on developing methods to detect and control chemical processes on the nanoscale, to create materials that are responsive to their local environment. The research goal incorporates many of the hallmarks of biological adaptability, based on feedback control between cellular receptors and protein expression. Similar artificial networks may be achieved by fabricating arrays of nanoscale devices that can detect and influence their local surroundings through ionic potential, temperature, mechanical motion, capacitance, or electrochemistry. These devices are particularly suited as smart biomaterials, where multiple surface-cell interactions must be monitored and adjusted simultaneously for optimal cell adhesion and growth. Other interests include precise control over self-assembled materials, and potential methods to monitor the diagnostics of complicated chemical systems, such as the effect of drug treatments within patients.
Molecular materials at interfaces
Directed dynamic self-assembly
Controlling molecular or biomolecular assembly and behavior
Influence of local electronic, optical or thermal stimuli
Denise M. Monack
Professor of Microbiology and Immunology
Current Research and Scholarly InterestsThe primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis. We use several model systems to study complex host-pathogen interactions in the gut and in immune cells such as macrophages and dendritic cells. Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response.
Avram Goldstein Professor in the School of Medicine and Professor, by courtesy, of Neurology and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsInformation transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice.
Assistant Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsThe long-term goal of our research is to understand the fundamental mechanisms that govern and reprogram cellular fate during development, regeneration and disease.
Mehran Mosley, MD MPH FAAP
Clinical Instructor, Pediatrics
Clinical Instructor, Pediatrics - General Pediatrics
Current Research and Scholarly InterestsHospitalized pediatric patients, care of children with severe neurological deficit, emerging infectious diseases, nutrition
Associate Professor of Biochemistry
Current Research and Scholarly InterestsOur lab seeks an agile and predictive understanding of how nucleic acids and proteins code for information processing in living systems. We develop new computational & chemical tools to enable the precise modeling, regulation, and design of RNA and RNA/protein machines.
Rebecca Seekamp, MD
Clinical Assistant Professor, Medicine - Primary Care and Population Health
Current Research and Scholarly InterestsInterested in complementary/alternative medicine, international health, international adoption medicine and providing full spectrum health care.
Beth L. Pruitt
Professor of Bioengineering and of Mechanical Engineering
Current Research and Scholarly InterestsWe are interested in microscale mechanics and MEMS-based metrologies primarily for small scale mechanics sensing and acutation. Applied research focuses on systems development and characterization. Fundamental research questions focus on mechanotransduction and cellular biomechanics.
R. Elaine Lambert
Adjunct Clinical Professor, Medicine - Immunology & Rheumatology
BioI began my career as a full-time faculty member at Stanford Healthcare in 1990 after over 3 years of rheumatology fellowship. Since 1996, I have worked in rheumatology private practice at Sports, Orthopedics and Rehabilitation Medicine Associates in Redwood City, CA while maintaining a volunteer position teaching house staff at Stanford Heathcare as Adjunct Clinical Professor of Medicine.
Stephen D. Coleman, M.D.
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsIndustry supported clinical trials
Assistant Professor of Biology
Current Research and Scholarly InterestsOur research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity.
Professor of Biomedical Data Science, of Genetics and, by courtesy, of Biology
Current Research and Scholarly InterestsMy research focuses on analyzing genome wide patterns of variation within and between species to address fundamental questions in biology, anthropology, and medicine. My group works on a variety of organisms and model systems ranging from humans and other primates to domesticated plant and animals. Much of our research is at the interface of computational biology, mathematical genetics, and evolutionary genomics.
Teresa Fu, MD
Clinical Assistant Professor, Dermatology
BioDr. Teresa Fu, a specialist in cutaneous oncology (high risk NMSC, Merkel), joined the department in September of 2015. A native of Texas, Dr. Fu received her BS from Rice University in 2006 and her medical degree from Stanford in 2011. She completed her Dermatology residency at Stanford in June of 2015 and is currently a member of SUNSPORT and the medical faculty at the Arbor Free Clinic. Dr. Fu’s professional interests include high-risk NMSC, Merkel cell carcinoma, and working with lasers. She has a special interest in skin cancers, including Merkel cell carcinoma, and is currently working on expanding the High-Risk Skin Cancer Clinic, which serves patients at increased risk for skin cancer due to organ transplantation or immunosuppression.
Clinical Assistant Professor, Pediatrics
BioDr. Pantaleoni is a Clinical Assistant Professor of Pediatrics in the division of Pediatric Hospital Medicine. She devotes her clinical time as a General Pediatric Hospitalist to the care of hospitaized children and their families at both Lucile Packard Children's Hospital and El Camino Hospital, in the Packard El Camino unit (PEC). She is also an Educator 4 CARE (E4C) at Stanford University School of Medicine and greatly enjoys fostering clinical skill development and professional identity formation with the Stanford medical students. Her scholarly interests surround undergraduate medical education, humanism in medicine and physician wellness.