School of Medicine
Showing 501-600 of 723 Results
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Stephen Quake
Lee Otterson Professor in the School of Engineering and Professor of Bioengineering, of Applied Physics and, by courtesy, of Physics
Current Research and Scholarly InterestsSingle molecule biophysics, precision force measurement, micro and nano fabrication with soft materials, integrated microfluidics and large scale biological automation.
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Thomas Quertermous, MD
William G. Irwin Professor of Cardiovascular Medicine
Current Research and Scholarly InterestsUnderstanding genetic basis of cardiovascular function and disease.
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Marlene Rabinovitch
Dwight and Vera Dunlevie Professor of Pediatric Cardiology
Current Research and Scholarly InterestsOur research program seeks to identify the cellular and molecular programs regulating vascular and lung development, through the use of cultured cells and tissues and mouse and rat models. We then determine how these programs are perturbed by genetic abnormalities or injurious processes associated with disease, focusing on pulmonary arterial hypertension (PAH), a fatal complication in children with heart defects, and a condition of unknown etiology primarily in young women.
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Ralph Rabkin
Professor of Medicine, Emeritus
Current Research and Scholarly InterestsDr Rabkin is examining the mechanism of the acquired resistance to hormones that develops in kidney failure.In particular he is studying the impact of kidney failure on the action of growth hormone and the role of impaired signal transduction as a cause of growth hormone resistance. He is also engaged in the study of growth factors in diabetic kidney disease.
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Thomas Raffin
The Colleen and Robert Haas Professor in Medicine and Biomedical Ethics, Emeritus
Current Research and Scholarly InterestsDr. Raffin is a clinician, teacher and investigator. He retired as Chief of the Division of Pulmonary and Critical Care Medicine in 2004. His key areas of academic interest include the biology and management of acute lung injury; basic biology of human lung and white cells; and, key issues in biomedical ethics including withholding and withdrawing life support, health care delivery, genomics, genetic screening, and neuroethics.
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Sameer Raina, MD, MBBS, MBA, FACC
Clinical Associate Professor, Medicine - Cardiovascular Medicine
BioDr. Raina is a board-certified cardiologist in the General Cardiology clinic at Stanford Health Care and a member of the Stanford Cardiovascular Institute. He is also a clinical associate professor in the Division of Cardiovascular Medicine.
His clinical interests include preventive cardiology, cardiac rehabilitation, and sports cardiology. In his recent positions at West Virginia University, he established the cardiology telemedicine program during and after the COVID pandemic. He applied his passion for cardiac rehab by creating individualized treatment plans for college athletes recovering from COVID. Dr. Raina is also passionate about building relationships with community doctors. He believes continuous communication is an essential part of excellent patient care.
Dr. Raina’s current research focuses on preventive cardiology, cardiac imaging, and outcomes research. He studies the outcomes of different cardiac interventions in specific patient populations. His research helps identify appropriate treatments for patients who have other conditions in addition to heart disease.
Dr. Raina eagerly anticipates joining the faculty of the Stanford South Asian Translational Heart Initiative (SSATHI). He is excited for the opportunity to address the high risk of cardiovascular diseases among South Asians. He looks forward to applying his clinical and research experience to support SSATHI’s mission to provide advanced care to ethnic populations disproportionately affected by these diseases.
Dr. Raina is a peer reviewer for several prestigious publications, including Neuropsychiatric Disease and Treatment and the International Journal of Chronic Obstructive Pulmonary Disease. He has also been an invited guest speaker at national and international meetings, including those for the International Congress of Cardiology and the World Congress of Cardiothoracic-Renal Diseases.
Dr. Raina is a fellow of the American College of Cardiology (FACC) and a member of the American College of Cardiology. -
Chandra Ramamoorthy
Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric), Emerita
Current Research and Scholarly InterestsNeuro protection and neurologic outcomes in cardiac patients prior to and concurrent with cardiac surgery and catheterization
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Thomas Rando, MD, PhD
Professor of Neurology
Current Research and Scholarly InterestsOur laboratory studies the molecular mechanisms regulating stem cell function, the effects of aging on skeletal muscle and skeletal muscle stem cells, and the pathogenesis and experimental therapeutics for hereditary muscle diseases, specifically the muscular dystrophies.
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Anoop Rao
Clinical Assistant Professor, Pediatrics - Neonatal and Developmental Medicine
Current Research and Scholarly InterestsWearable senors, unobtrusive vital sign monitoring, natural language processing/text mining
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Mohammad Reza Rasouli, MD
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
BioDr. Rasouli is a board-certified anesthesiologist specializing in pain management. He practices at Stanford Health Care – ValleyCare in Pleasanton. He is also a clinical assistant professor in the Stanford University School of Medicine Department of Anesthesiology, Perioperative & Pain Medicine.
Dr. Rasouli takes pride in developing a comprehensive, compassionate treatment plan personalized to each patient in his care. His goals are to
relieve patients’ chronic pain, and enable them to enjoy the best possible
quality of life. In addition to his clinical practice, Dr. Rasouli has conducted research and published extensively. He was a postdoctoral research fellow at the Rothman Institute of Orthopaedics at Thomas Jefferson University in Philadelphia.
Dr. Rasouli has presented the findings of his research at conferences such as the North American Neuromodulation Society Annual Meeting, American Society of Regional Anesthesia and Pain Medicine Meeting, American Society of Anesthesiology Annual Meeting, International Anesthesia Research Society Annual Meeting, and Society of Critical Care Anesthesiologists Annual Meeting. Topics have included using spinal cord and peripheral nerve stimulation for treatment of pain, perioperative pain management, and post-surgical recovery.
He has published more than 100 articles in the peer-reviewed journals Anesthesiology, Anesthesia and Analgesia, Neurosurgery, Lancet, JAMA, Annals of Surgery, and elsewhere. He also has co-authored chapters in Spine Trauma, Epidemiology of Spinal Cord Injuries, Pain Management Following Total Hip Arthroplasty and Total Knee Arthroplasty, and Epidemiology, Diagnosis and Treatment of Sciatica, and other textbooks.
Dr. Rasouli has earned numerous honors including the Dr. Jeffrey and Celia Joseph Anesthesiology Scholarly Achievement Award. He is a member of the American Society of Anesthesiologists, California Society of Anesthesiologists, American Society of Regional Anesthesia and Pain Medicine, North American Neuromodulation Society, American Society of Pain and Neuroscience, and Society of Critical Care Medicine. -
Kristy Red-Horse
Professor of Biology
Current Research and Scholarly InterestsCardiovascular developmental biology
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Sushma Reddy
Associate Professor of Pediatrics (Cardiology)
Current Research and Scholarly InterestsMy laboratory's expertise in cardiovascular phenotyping has led to the development of mouse models of congenital heart disease that recapitulate abnormal loading conditions on the heart. We have used these models to advance our understanding of the mechanisms of right heart failure in children and adults with congenital heart disease with the long term goal of identifying noninvasive diagnostic tools to better assess right ventricular health and to develop right ventricle specific therapeutics.
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Risheen Reejhsinghani
Clinical Associate Professor, Medicine - Cardiovascular Medicine
BioRisheen Reejhsinghani obtained her medical degree in Mumbai, India, followed by an internal medicine residency at St. Elizabeth's Medical Center in Boston, MA and cardiology fellowship at Baystate Medical Center/Tufts University School of Medicine, where she served as one of the chief fellows. She subsequently completed an advanced echocardiography fellowship at the University of California, San Francisco, and is board certified in echocardiography, general cardiology, and nuclear cardiology.
Dr. Reejhsinghani practices as a general cardiologist in the Division of Cardiovascular Medicine at Stanford University School of Medicine, where she also serves as the associate director for the hospital-based consultative cardiology service. As a clinical cardiologist, she believes strongly in the tenets of evidence-based practice, diagnostic cognizance, and patient education. She also has a specific interest in the burgeoning field of Cardio-Rheumatology, focused on cardiac diseases among patients with rheumatologic conditions such as rheumatoid arthritis, systemic lupus erythematosus, scleroderma, and ankylosing spondylitis, among others. Her clinical research in this area has focused on the evaluation of structural cardiac disease and diastolic dysfunction in ankylosing spondylitis patients, primarily using echocardiography.
Dr. Reejhsinghani has an academic focus in medical education, and believes that instilling a love for bedside medicine and the physical exam is the soundest way to empower future generations of learners. To this end, she received additional training in clinical teaching and simulation at the University of California, San Francisco, and has worked extensively on curriculum and course design. She currently serves as the associate program director of the cardiovascular medicine fellowship at Stanford, and is an associate course director for the Year 1 Practice of Medicine Course at the Stanford University medical school. Dr. Reejhsinghani also enjoys writing, particularly about medical education and has written articles for international newspapers, among other publications. -
Olaf Reinhartz
Associate Professor of Cardiothoracic Surgery
Current Research and Scholarly Interests1. Mechanical circulatory support in failing Fontan circulation
2. Pathophysiologic response to fetal cardiac surgery.
3. Various clinical projects in pediatric cardiothoracic surgery -
Juan Rivas-Davila
Associate Professor of Electrical Engineering and Senior Fellow at the Precourt Institute for Energy
Current Research and Scholarly InterestsModern applications demand power capabilities beyond what is presently achievable. High performance systems need high power density and bandwidth that are difficult to achieve.
Power density can be improved with better semiconductors and passive componets, and by reducing the energy storage requirements of the system. By dramatically increasing switching frequency it is possible to reduce size of power converters. I'm interested in high performance/frequency circuits switching >10 MHz. -
Thomas Robinson
The Irving Schulman, M.D. Professor of Child Health, Professor of Medicine (Stanford Prevention Research Center) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsDr. Robinson originated the solution-oriented research paradigm and directs the Stanford Solutions Science Lab. He is known for his pioneering obesity prevention and treatment research, including the concept of stealth interventions. His research applies social cognitive models of behavior change to behavioral, social, environmental and policy interventions for children and families in real world settings, making the results relevant for informing clinical and public health practice and policy.
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Stanley G. Rockson, MD
Allan and Tina Neill Professor of Lymphatic Research and Medicine
Current Research and Scholarly InterestsMy clinical research includes studies on risk factor modification in atherosclerosis and coronary artery disease; clinical trials involving medical therapies for peripheral arterial insufficiency; coronary angiogenesis; therapy of lymphedema; atherand photodynamic therapy in atherosclerosis.
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Fatima Rodriguez
Associate Professor of Medicine (Cardiovascular Medicine)
BioFatima Rodriguez, MD, MPH is an Associate Professor in Cardiovascular Medicine and (by courtesy) the Stanford Prevention Research Center. Dr. Rodriguez earned her medical degree from Harvard Medical School and her MPH from the Harvard School of Public Health. She then completed internal medicine residency at Brigham and Women’s Hospital and fellowship in cardiovascular medicine at Stanford University. She currently serves as the Section Chief of Preventive Cardiology. Dr. Rodriguez specializes in cardiovascular disease prevention, inherited lipid disorders, and cardiovascular risk assessment in high-risk populations.
Dr. Rodriguez’s research includes a range of topics around racial, ethnic, and gender disparities in cardiovascular disease prevention, developing novel interventions to address disparities, and opportunistic screening of coronary artery disease. -
Albert "A.J." Rogers, MD, MBA
Instructor, Medicine - Cardiovascular Medicine
BioDr. Albert “A.J.” Rogers, MD, MBA is a clinical cardiac electrophysiologist and cardiovascular research scientist at Stanford University. He is trained in cardiac electrophysiology, biomedical and software engineering, signal processing, and data science. Clinically, his expertise is in complex arrhythmia mapping and ablation, including atrial fibrillation, supraventricular tachycardia, and ventricular tachycardia. He also performs cardiac device implantation of leadless pacemakers, conduction system pacing, cardiac resynchronization therapy, defibrillators, and event recorders. In research, he is supported by the National Institutes of Health (NIH) and other agencies to investigate pathophysiology, diagnosis, and treatment of heart rhythm disorders. His research explores the mechanisms of cardiac arrhythmia using signal processing, machine learning, and in silico modeling. He has over 10 years of medical technology innovation and development experience ranging from design to preclinical and clinical studies.
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Angela Rogers
Associate Professor of Medicine (Pulmonary and Critical Care)
Current Research and Scholarly InterestsWe use genetics and genomics methodologies to identify novel ARDS pathobiology; we hope that this will enable identification of novel biomarkers, phenotypes, and treatments for the disease. We are building a plasma biobank of critically ill patients at Stanford, with a particular focus on metabolic changes in critical illness.
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Rajat Rohatgi
Professor of Biochemistry and of Medicine (Oncology)
Current Research and Scholarly Intereststhe overall goal of my laboratory is to uncover new regulatory mechanisms in signaling systems, to understand how these mechanisms are damaged in disease states, and to devise new strategies to repair their function.
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Morteza Roodgar DVM, PhD
Veterinarian Research Scientist, Genetics
BioDr. Morteza Roodgar is a veterinarian scientist with a research focus on Primate induced Pluripotent Stem Cells (iPSCs) and long-read genomics tools.
Dr. Roodgar's research focus is on primate stem cell biology, immunology, and comparative genomics of nonhuman primate models for human diseases. The long-term goal of Dr. Roodgar's research is to Replace, Reduce and Refine (aka 3 R’s) the use of animals in biomedical research leveraging primate induced pluripotent stem cells (iPSCs) and long-read genomic tools to speed up preclinical testing.
Previous research includes immunology and genomic susceptibility to infectious diseases (e.g., tuberculosis, TB) in nonhuman primate models, Preventive Veterinary Medicine and emerging zoonotic diseases (e.g., COVID-19 and Monkeypox). -
Michal Bental Roof
Academic Prog Prof 3, Pediatrics - Cardiology
Current Role at StanfordI joined the Cardiopulmonary Research Program of Drs. Rabinovitch and Bland at Stanford University in 2002, as the Academic and Research Program Officer, and since 2020 assumed my role at the Basic Science and Engineering (BASE) Initiative at the Betty Irene Moore Children's Heart Center, directed by Dr. Rabinovitch. I organize the educational activities of the lab, and assist the faculty and fellows with the preparation of grant proposals, IRB, APLAC and Biosafety protocols, manuscripts, and presentations. I served as the Site Coordinator for the Stanford Transplant Procurement Center of the Pulmonary Hypertension Breakthrough Initiative (PHBI), headed by Dr. Rabinovitch,that now evolved into the Stanford Transplant Tissue Bank. In this capacity, I oversee patient recruitment, data collection and reporting, and ensure compliance with university and federal guidelines. I coordinated and prepared the application for an Investigational New Drug (IND) and the pre-IND meeting that preceded that, for Elafin as a therapy for pulmonary arterial hypertension (PAH) to the FDA in August 2017, and with the Study PIs coordinated the Phase 1 clinical trial “Safety and Tolerability of Escalating Doses of Subcutaneous Elafin (Tiprelestat) Injection in Healthy Normal Subjects” that followed.
From 2005-2015, I served as the Administrative Coordinator of the Cardiovascular and Pulmonary Science Scholarly Concentration for medical students at Stanford University School of Medicine. This includes facilitating communication of the four co-Directors with the School of Medicine Administration, the medical students, and the faculty mentors. An important component of this role is the coordination of the MED223 course, a medical school course where faculty and fellows present new developments in cardiovascular science in the form of a journal club. From 2013-2018, I was the coordinator for the NIH-NHLBI T32 “Mechanisms and Innovation in Vascular Disease” (PI: RL Dalman), and from 2013 to date for NIH-NHLBI K12 HL120001 “Stanford Career Development Program in ‘Omics’ of Lung Disease”. (PIs: M Rabinovitch, MR Nicolls and MP Snyder). This included recruitment of candidates, oversight of training activities, ensuring compliance with NIH and Stanford policies, and acting as a liaison between the trainees and the Directors to facilitate effective communication.
Prior to joining Stanford, I was Associate Director (Scientific Development Administrator) at the Institute for Medicine and Engineering, directed by Dr. Peter Davies at the University of Pennsylvania. In this role, I was the liaison with federal funding agencies and organized multi-investigator program projects and training grants. -
Allyson Rosen, Ph.D., ABPP-CN
Clinical Professor (Affiliated), Psych/Public Mental Health & Population Sciences
Staff, Psychiatry and Behavioral SciencesBioRESEARCH FOCUS
Translational cognitive neuroscience of aging and dementia. Neuroethics.
TRAINING
Dr. Rosen is board certified in clinical neuropsychology with a geriatric focus. She completed college at Brown University, a clinical psychology Ph.D. from Case Western Reserve University, clinical neuropsychology internship at the Long Island Jewish Hospital in New York, and clinical neuropsychology postdoctoral fellowship at the Medical College of Wisconsin. Dr. Rosen completed specialty research fellowship training at the National Institute on Aging (Intramural Research Training Award) and Stanford (NRSA F32, K01) in functional imaging and noninvasive brain stimulation with support from NIA.
CLINICAL AND RESEARCH ACTIVITIES
Dr. Rosen is Director of Dementia Education at the Mental Illness Research Education and Clinical Center at the Palo Alto VAHCS. She is also a neuropsychologist and part of the consensus clinical group and education core at the Stanford’s Alzheimer’s Disease Research Center (NIA). Dr. Rosen’s funded research has focused on applying cognitive neuroscience of aging to improve clinical practice in older adults by using cognitive measures, brain imaging, and noninvasive brain stimulation such as TMS. Studies include using fMRI as an outcome measure for cognitive training, studying how to improve the accuracy of transcranial magnetic stimulation targeting with and without image guidance, and using structural MRI to avoid postoperative cognitive decline and improve outcome from carotid vascular procedures. She has a longstanding commitment to neuroethics and leads a feature in the Journal of Alzheimer Disease that focuses on ethical issues in new and emerging AD applications.
ETHICS EDITOR, JOURNAL OF ALZHEIMER'S DISEASE
Ethics Review
http://www.j-alz.com/blogs/discussion/protecting-progress
MIRECC DEMENTIA EDUCATION
http://www.mirecc.va.gov/visn21/education/dementia_education.asp -
David Rosenthal
Professor of Pediatrics (Pediatric Cardiology)
Current Research and Scholarly InterestsResearch interests include the study of Heart Failure, Cardiomyopathy and ventricular dysfunction in children, from a clinical perspective. Investigations include clinical trials of medications, cardiac resynchronization, and mechanical circulatory support.
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Stephen J. Roth
Professor of Pediatrics (Cardiology)
Current Research and Scholarly InterestsRandomized Therapeutic Trials in Pediatric Heart Disease, NIH/U01 GrantNo. HL68285 2001-2006.
Heparin and the Reduction of Thrombosis (HART) Study. Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006.
A Pilot Trial fo B-type Natriuretic Peptide for Promotion of Urine Output in Diuretic-Resistant Infants Following Cardiovascular Surgery.Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006. -
Chawannuch Ruaengsri
Clinical Assistant Professor, Cardiothoracic Surgery
Current Research and Scholarly Interests- Cardiac Transplant
- Mechanical Circulatory Support
- Atrial Fibrillation Surgery
- Minimally Invasive Cardiac Surgery -
Daniel Rubin
Professor of Biomedical Data Science, of Radiology (Integrative Biomedical Imaging Informatics at Stanford), of Medicine (Biomedical Informatics Research) and, by courtesy, of Ophthalmology
Current Research and Scholarly InterestsMy research interest is imaging informatics--ways computers can work with images to leverage their rich information content and to help physicians use images to guide personalized care. Work in our lab thus lies at the intersection of biomedical informatics and imaging science.
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Michael Salerno
Professor of Medicine (Cardiovascular) and of Radiology (Cardiovascular Imaging)
BioDr. Salerno completed his BS in Biological Engineering at Cornell University, and his MD and PhD in Biomedical Engineering at the University of Virginia as part of the Medical Scientist Training Program. He then completed the American Board of Internal Medicine Research Pathway with an Internal Medicine residency at Stanford University, and his general cardiology fellowship at Duke University Medical Center. During his time at Duke he completed a dedicated year in cardiovascular MRI at the Duke Cardiovascular MR Imaging Center. He returned to UVA in 2008 to complete a 2-year advanced cardiovascular imaging fellowship where he trained in CMR and cardiovascular CTA. He achieved COCATS Level III training in all cardiovascular imaging modalities (Echo, Nuclear, CMR, CCT), and is board certified in Echocardiography and Nuclear Cardiology. He served as faculty at UVA in Cardiology, Radiology, and Biomedical Engineering from 2010-2021 where he was the Director of Cardiac MRI and the Medical Director of Echocardiography, before returning to Stanford.
His research involves the development and evaluation of novel MRI pulse sequences and techniques to improve the clinical utility of CMR imaging. The current focus of the research is on quantitative myocardial perfusion imaging, quantitative imaging of myocardial fibrosis, rapid free-breathing and self-gated imaging, and deep learning for image reconstruction and post-processing. His laboratory includes undergraduate and graduate engineering students as well as clinical cardiovascular imaging fellows to bring new advances into clinical practice. Dr. Salerno has been in the field of MRI for 25 years and holds multiple patents related to the development and application of novel pulse sequences for MRI. He has received numerous research awards, and has published extensively in the areas of MRI, cardiovascular MRI and multi-modality cardiovascular imaging. His research has been supported by the AHA and the National Institutes of health. He is a deputy editor for JACC Cardiovascular Imaging.
Outside of work, Dr. Salerno enjoys sailing, rock climbing, skiing, running, biking, hiking, and spending time with his wife Cherie, and his two boys Christopher and Joseph. -
Karim Sallam, MD
Assistant Professor of Medicine (Cardiovascular Medicine)
BioKarim Sallam, MD, is trained in Cardiovascular Medicine and Advanced Heart Failure.
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Darren Salmi
Clinical Assistant Professor, Pathology
Current Research and Scholarly InterestsCardiovascular pathology, congenital heart disease, autopsy, medical education
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Jacinda Sampson
Clinical Professor, Neurology & Neurological Sciences
BioDr. Jacinda Sampson received her MD and a PhD in biochemistry from University of Alabama at Birmingham, and completed her neurology residency and neurogenetics fellowship at the University of Utah. She served at Columbia University Medical Center prior to joining Stanford University Medical Center in 2015. Her areas of interest include myotonic dystrophies, Duchenne muscular dystrophy, and neurogenetic disorders such as neurofibromatosis, hereditary spastic paraparesis, spinocerebellar ataxia, among others. She is interested in clinical trials for treatment of neurogenetic disorders, and in the clinical application of next-generation genomic sequencing to genetic testing.
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Alexander Tarlochan Singh Sandhu
Assistant Professor of Medicine (Cardiovascular Medicine)
BioAlex Sandhu, MD, MS is a cardiologist with a special interest in the care of patients with advanced heart failure. He graduated from the seven-year combined BA-MD program at Northwestern with a focus on economics and mathematics. He completed an internal medicine residency at Stanford University, spending 16 weeks at Makerere Hospital in Uganda as part of the Global Health track. He subsequently earned a Masters in Health Services Research at Stanford while acting as a fellow in health services research at the Palo Alto VA and Stanford's Center for Health Policy/Primary Care and Outcomes Research. Next, he completed fellowships in cardiology and advanced heart failure and transplant at Stanford before joining the faculty.
Alex is now an active clinician and heart failure researcher who focuses on health economics, the implementation of high-value care strategies, comparative effectiveness, and innovative clinical trial design. He is passionate about patient care and finding ways to bring meaningful improvements to patients’ lives. He is involved in several clinical trials including the K-23 funded PRO-HF (patient centered quality of life assessments), DOT-HF (mobile device based implementation trial), and a CAC notification pilot trial (patient centered coronary artery calcification notification).
In his free time, he enjoys playing soccer as well as entertaining and being entertained by his joyful sons, Kyle and Tyler. -
Everton Jose Santana
Visiting Instructor/Lecturer, Medicine - Cardiovascular Medicine
BioEverton is currently a Visiting Instructor at Stanford University, Division of Cardiovascular Medicine in the School of Medicine.
He has received his BSc degree in Electrical Engineering (2019) and MSc degree in Computer Science (2021) by the State University of Londrina (UEL), Brazil. From 2015 to 2016, he was an exchange student at Hanze University of Applied Sciences, the Netherlands, where he followed minors in Biomedical and Sensor System Engineering.
He has worked with several Research and Development projects, englobing Machine Learning and Instrumentation Engineering applied to many domains.
He has also worked as a Professor at the Pontifical Catholic University of Paraná in the Cyber-Physical Systems theme.
His current research interest is in Data Science applied to Biomedical Signals. -
Nazish Sayed MD, PhD
Assistant Professor (Research) of Surgery (Vascular Surgery) and at the Stanford Cardiovascular Institute
Current Research and Scholarly InterestsThe Sayed Laboratory is focused on the development of novel technologies that drive innovation in regenerative medicine, disease modeling, and drug testing in vascular biology. The lab conducts translational research in vascular biology and aims to understand the role of the vasculature in the development of cardiac diseases, including those due to inherited genetic variants or environmental insults such as type 2 diabetes or hypertension. The lab employs the human induced pluripotent stem cell (iPSC) technology to generate patient-specific vascular cells (endothelial and vascular smooth muscle cells) as an alternative to animal models providing a human tissue surrogate for research that is scalable and sustainable. By employing this unique platform, the lab also investigates the role of chemotherapeutic agents (anti-cancer drugs) on the vasculature. Dr. Sayed’s lab has also established an endothelial regeneration program, where they leverage the innate immune system to regenerate endothelial cells from human fibroblasts.
Work from the lab has led to seminal discoveries in the areas of 1) Nitric oxide (NO) biology, (2) vascular biology, (3) stem cell biology, (4) cardiovascular disease modeling (5) cardio-oncology. -
Ingela Schnittger, MD
Professor of Medicine (Cardiovascular)
Current Research and Scholarly InterestsMy main research continues to be in the field of echocardiography. Several areas of research are currently being pursued.
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Donald Schreiber
Associate Professor of Emergency Medicine at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsMy research group focuses on the diagnosis and treatment of cardiovascular emergencies including acute myocardial infarction, acute coronary syndrome and congestive heart failure. We have evaluated novel cardiac markers and point-of-care testing in clinical practice. Current projects also include the diagnosis and treatment of acute pulmonary embolism and deep venous thrombosis. Other interests include spinal cord injury, pneumonia and sepsis.
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John S. Schroeder, MD
Professor (Clinical) of Medicine (Cardiovascular), Emeritus
Current Research and Scholarly Interests1. Clinical Pharmocology of Cardiovascular Drugs
(a) Calcium Channel Blockers
(b) Agents for Heart Failure
(c) Anti-atherosclerotic Effects of Cardiovascular Drugs, e.g. Calcium Channel Blockers
2. Cardiac Transplantation/Congestive Heart Failure
3. Coronary Artery Spasm -
Katharine Sears Edwards
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
Current Research and Scholarly InterestsPotential impact of brief behavioral interventions to improve adjustment, coping, medical adherence, and cardiovascular health among cardiac patients.
Psychosocial challenges of patients with spontaneous coronary artery dissection (SCAD).
Assessment and training in evidence-based psychological therapies. -
Vittorio Sebastiano
Associate Professor (Research) of Obstetrics and Gynecology (Reproductive and Stem Cell Biology)
Current Research and Scholarly InterestsThe thread of Ariadne that connects germ cells, preimplatation development and pluripotent stem cells is the focus of my research, with a specific interest in human development. My long-term goals are: 1. Understanding the biology of germ cells and and their ability to sustain early preimplantation development; 2. Understanding the mechanisms that regulate very early cell fate decisions in human embryos; 3. Understanding the biology of derivation and maintenance of Pluripotent Stem Cells
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Zachary M. Sellers, MD, PhD
Adjunct Professor, Pediatrics - Gastroenterology
BioDr. Sellers is a pediatric physician-scientist and research and clinical development consultant. As a pediatric gastroenterologist and ion channel physiologist, Dr. Sellers' work in academia and pharma over the last 20 years has focused on improving the lives of individuals with complex and rare diseases through providing cutting-edge clinical care and advancing research and drug development. Dr. Sellers previously led a basic and translational research laboratory at Stanford, focused on epithelial ion transport and acid-base regulation using a variety of human and animal models. He is a firm believer in the exponential impact of team science and is adept working in multi-disciplinary and cross-functional teams. He seeks out strategic partnerships and opportunities that can leverage his expertise and leadership to advance innovative therapies for areas of high unmet need and to support the development of the next generation of physician-scientists. Dr. Sellers received his BS (Animal Physiology and Neuroscience) and BA (Japanese Studies) from the University of California. San Diego, his MD and PhD (Molecular and Integrative Physiology) from the University of Illinois at Urbana-Champaign, and was trained in Pediatrics and Pediatric Gastroenterology, Hepatology, and Nutrition at Stanford, where he was previously a faculty member and attending physician. He held multiple leadership positions at Stanford, including Associate Chief of Research in Gastroenterology, Director of the Stanford Children's Pancreas Program, Lead Gastroenterologist for the CF Program, Director of the CFTR Phenotyping and Theratyping Program, and Physician-Scientist Advisor for the Pediatrics Residency Program.
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Nigam H. Shah, MBBS, PhD
Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Current Research and Scholarly InterestsWe analyze multiple types of health data (EHR, Claims, Wearables, Weblogs, and Patient blogs), to answer clinical questions, generate insights, and build predictive models for the learning health system.
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Rajan Lalit Shah
Affiliate, Medicine - Med/Cardiovascular Medicine
BioDr. Rajan Shah is a cardiac electrophysiologist concentrating on the treatment of arrhythmias, especially those of complex origins. He prides himself on delivering personalized attention, compassion, and high-quality care to optimize the needs of his patients with abnormal heart rhythms. His experiences in Detroit, where he was raised, exposed him to a wide range of beautiful cultures and backgrounds, and solidified his decision to pursue a career focused on the wellbeing of people.
He completed his sub-specialty fellowship at Stanford University where he received 2 years of highly specialized training dedicated to the treatment of genetic arrhythmia syndromes and management of complex heart rhythm disorders. Dr. Shah continues his profession at Stanford Health Care and is grateful for the opportunity to care for a diverse population, employing his expertise in state-of-the-art therapies including minimally-invasive catheter ablation (ex: ventricular tachycardia, atrial fibrillation) and device implantation (ex: conduction system and leadless pacing) to better the health outcomes of his patients with various arrhythmias. In his clinical role, Dr. Shah additionally directs the East Bay Familial Inherited Arrhythmia Clinic concentrated on the tailored-treatment of genetic arrhythmia syndromes and the prevention of sudden cardiac death in individuals and families. -
Rahul P Sharma, MBBS, FRACP
Clinical Associate Professor, Medicine - Cardiovascular Medicine
Current Research and Scholarly InterestsTranscatheter valve therapies, CT valve imaging, AI and device innovation
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Andrew Young Shin
Clinical Professor, Pediatrics - Cardiology
Current Research and Scholarly InterestsSURF PROGRAM
The SURF program is an innovative collaboration between LPCH, Stanford University Hospital and the Stanford School of Engineering. The program has focused on improving quality and safety of patient care, improving hospital operations and promoting clinical effectiveness utilizing contemporary technologies such as machine learning, mathematical optimization, simulation and a variety of statistical, probabilistic and computational tools. The program has 2 independent funding mechanism to primarily improve patient care/hospital operations and improve academics for faculty within the department of Pediatrics at LPCH.
https://surf.stanford.edu/
CLINICAL EFFECTIVENESS
The Clinical Effectiveness (CE) Program is a funded program that aims to understand and improve unnecessary variation in healthcare delivery in order to optimize quality of care and reduce wasteful expenditures. The CE program has developed innovative programs such as Target Based Care, an award-winning intervention to reduce variation in hospital length of stay and currently a multi-center trial involving more than 20 hospitals in North America. In 2016, the CE program included the first CE fellowship program in a pediatric training program with 3 cycles of graduates. The CE program is supported by LPCH and a philanthropic gift by Susan Choe and Thomas Tobiason. -
Judith Shizuru
Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy)
Current Research and Scholarly InterestsTransplantation of defined populations of allogeneic hematopoietic cells. Specifically, the way in which hematopoietic cell grafts alter antigen specific immune responses to allo-, auto- and viral antigens. The cellular and molecular basis of resistance to engraftment of allogeneic hematopoietic stem cells.
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Joseph Shrager
Professor of Cardiothoracic Surgery
Current Research and Scholarly InterestsIn clinical research, Dr. Shrager studies outcomes in a variety of areas within Thoracic Surgery including: parenchyma-sparing operations and minimally invasive resections for lung cancer, transcervical thymectomy for myasthenia gravis, diaphragm plication, and surgical treatment of emphysema.
Dr. Shrager's lab is focused on the impact of disease states upon the diaphragm. His group published the seminal paper (NEJM) describing diaphragm atrophy assoc'd with mechanical ventilation. -
Yasuhiro Shudo, MD, PhD
Clinical Assistant Professor, Cardiothoracic Surgery
BioDr. Shudo is a board-certified cardiothoracic surgeon and clinical assistant professor in the Department of Cardiothoracic Surgery at Stanford University School of Medicine.
His clinical focus is the surgical treatment of end-stage cardiopulmonary failure, including heart transplant, heart-lung transplant, lung transplant, mechanical circulatory support (MCS), and extracorporeal membrane oxygenation (ECMO). He has published numerous landmark papers
and chapters.
Dr. Shudo also performs mitral valve repair/replacement (MVR), aortic valve replacement (AVR), complex valve surgery, coronary artery bypass graft (CABG) surgery, reoperative cardiac surgery, minimally invasive surgery, and transcatheter aortic valve replacement (TAVR).
Dr. Shudo is fully committed to innovative, comprehensive, and compassionate care for each patient he treats. -
Dawn H. Siegel, MD
Clinical Professor, Dermatology
Clinical Professor (By courtesy), PediatricsCurrent Research and Scholarly InterestsI'm dedicated to connecting patients with clinical research trials and contributing to research on specific skin conditions particularly hemangiomas, birthmarks, and PHACE syndrome. My research also aims to develop solutions to health disparities through improved access to pediatric dermatologists and treatments.
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Julia Fridman Simard
Associate Professor of Epidemiology and Population Health, of Medicine (Immunology & Rheumatology) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine)
BioJulia Fridman Simard, ScD, is an Associate Professor of Epidemiology & Population Health, and, by courtesy, of Medicine in Immunology and Rheumatology and Obstetrics and Gynecology in Maternal Fetal Medicine at Stanford University School of Medicine.
Dr. Simard earned her Masters and Doctorate of Science in Epidemiology degrees at the Harvard School of Public Health. During that time she trained with investigators at the Section of Clinical Sciences, Division of Rheumatology, Immunology, and Allergy at Brigham and Women’s Hospital and the Cardiovascular Epidemiology Research Unit at Beth Israel Deaconess Medical Center. In 2008, Dr. Simard relocated to Sweden to begin a Postdoctoral Fellowship in Clinical Epidemiology at the Karolinska Institutet in Stockholm. She became an Assistant Professor in their Clinical Epidemiology Unit in 2011, and was later honored with a Karolinska Institutet Teaching Award. Leveraging the population-based registers of Sweden, Dr. Simard initiated a national register linkage study to examine the utility of registers in Systemic Lupus Erythematosus (SLE) research and develop an extensive data repository for future epidemiologic investigations.
While maintaining a close collaboration with the Karolinska Institutet, she joined Stanford’s Epidemiology faculty in 2013. Dr. Simard studies outcomes such as malignancy, stroke, infection, and mortality, in patients with systemic autoimmune rheumatic diseases with a focus on systemic lupus erythematosus. Recently her primary research focus has shifted to the intersection between reproductive epidemiology and rheumatic disease fueled by a K01 career development award from the NIH (NIAMS) to study maternal and fetal outcomes in systemic lupus pregnancy. This led to collaborations with colleagues at Stanford, throughout the US, and abroad, and a series of projects focused on the diagnosis of preeclampsia and associated risks in pregnant women with systemic lupus. Dr. Simard was awarded a Peter Joseph Pappas Research Grant from the Preeclampsia Foundation for her lab's work examining preeclampsia risk in high-risk populations, and a McCormick Faculty Award from Stanford Medicine to take important steps towards disentangling preeclampsia from lupus nephritis. Dr. Simard is leading an international study of hydroxychloroquine in lupus pregnancy leveraging mixed methods in partnership with qualitative researchers, patients, clinicians, and epidemiologists in Sweden, Canada, and in the United States.
In addition to these issues of misclassification in reproductive rheumatology questions, Dr. Simard's lab is also interested in how misclassification, missed opportunities, and misdiagnosis contribute to disparities in complex conditions such as systemic lupus. In addition to methodologic issues around misclassification and bias and the largely clinical epidemiology focus of her work, Dr. Simard's work examines social determinants of health and health disparities. Dr. Simard was recently awarded an R01 from NIH (NIAID) to study the role of cognitive and unconscious bias in clinical decision making for female-predominant diseases including lupus. -
Robert Simoni
Professor, Biology
Current Research and Scholarly InterestsCholesterol in biological membranes; genetic mechanisms & cholesterol production
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Michael Snyder, Ph.D.
Stanford W. Ascherman Professor of Genetics
Current Research and Scholarly InterestsOur laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states
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Sulaiman Somani
Affiliate, Department Funds
Resident in Graduate Medical EducationCurrent Research and Scholarly Interestscomputer vision, personalized medicine, cardiology, clinical informatics
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Edda Spiekerkoetter
Associate Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly InterestsPulmonary Arterial Hypertension
Pulmonary Vascular Remodeling
Modulation of BMPR, ENG, ACVRL1 (ALK1), SMAD signaling
Structural and molecular programs governing right ventricular adaptation and failure
Hereditary Hemorrhagic Telangiectasia
Pulmonary Arteriovenous malformations
Computational Drug Prediction and Repurposing
Deep Tissue Confocal Imaging -
Joshua M. Spin
Clinical Associate Professor, Medicine - Cardiovascular Medicine
Current Research and Scholarly InterestsDr. Spin began his research career studying the structural biology of low density lipoprotein, and has been augmenting his skills with intensive training in molecular biology techniques, particularly those involving high-throughput genetic expression profiling. He is especially interested in vascular smooth muscle cells, and the role of smooth muscle differentiation and phenotypic switching in development and vascular disease. His latest work has focused on the biology of aortic aneurysms.
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James Spudich
Douglass M. and Nola Leishman Professor of Cardiovascular Disease, Emeritus
Current Research and Scholarly InterestsThe general research interest of this laboratory is the molecular basis of cell motility, with a current emphasis on power output by the human heart. We have three specific research interests, the molecular basis of energy transduction that leads to ATP-driven myosin movement on actin, the biochemical basis of the regulation of actin and myosin interaction and their assembly states, and the roles these proteins play in vivo, in cell movement, changes in cell shape and muscle contraction.
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Marcia L. Stefanick, Ph.D.
Professor (Research) of Medicine (Stanford Prevention Research Center), of Obstetrics and Gynecology and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsMarcia L. Stefanick, Ph.D is a Professor of Medicine Professor of Obstetrics and Gynecology, and by courtesy, Professor of Epidemiology and Population Health at Stanford University School of Medicine. Dr. Stefanick’s research focuses on chronic disease prevention (particularly, heart disease, breast cancer, osteoporosis, and dementia) in both women and men. She is currently the Principal Investigator the Women’s Health Initiative (WHI) Extension Study, having been the PI of the Stanford Clinical Center of the landmark WHI Clinical Trials and Observational Study since 1994 and Chair of the WHI Steering and Executive Committees from 1998-2011, as well as PI of the WHI Strong and Healthy (WHISH) Trial which is testing the hypothesis that a DHHS-based physical activity intervention, being delivered to a multi-ethnic cohort of about 24,000 WHI participants across the U.S., aged 68-99 when the trial started in 2015, will reduce major cardiovascular events over 8 years, compared to an equal number of “usual activity” controls. Dr. Stefanick is also PI of the Osteoporotic Study of Men (MrOS) which is continuing to conduct clinical assessments of bone and body composition in survivors of an original cohort of nearly 6000 men aged 65 and over in 2001. As founding Director of the Stanford Women’s Health and Sex Differences in Medicine (WHSDM, “wisdom”) Center, she plays a major role in promoting research and teaching on Sex and Gender in Human Physiology and Disease, Women’s Health and Queer Health and Medicine. Dr. Stefanick also plays major leadership roles at the Stanford School of Medicine, including as co-leader of the Population Sciences Program of the Stanford Cancer Institute, Stanford’s NCI-funded comprehensive cancer center.
Dr. Stefanick obtained her B.A. in biology from the University of Pennsylvania, Philadelphia, PA (1974), then pursued her interest in hormone and sex difference research at the Oregon Regional Primate Research Center, after which she obtained her PhD in Physiology at Stanford University, focusing on reproductive physiology and neuroendocrinology, with exercise physiology as a secondary focus. Her commitment to human research led to a post-doctoral fellowship in Cardiovascular Disease Prevention at the Stanford Prevention Research Center, which has been her academic home for nearly 40 years. -
Lea Steffes
Instructor, Pediatrics - Pulmonary Medicine
BioDr. Steffes, a Wisconsin native, completed medical school and pediatric residency at the Medical College of Wisconsin. She then moved to the Bay Area and completed her clinical fellowship in pediatric pulmonary medicine at Stanford University in 2020. Additionally, Dr. Steffes received further post-doctoral training in the laboratories of Dr. Maya Kumar and Dr. David Cornfield, studying the cellular and molecular mechanism driving pulmonary vascular disease. In addition to her role as an Instructor in Pediatrics in the division of Pulmonary Medicine, Dr. Steffes is also completing an advanced clinical fellowship in Pulmonary Hypertension at Lucile Packard Children’s Hospital Stanford. Her clinical work consists of caring for patients with pediatric pulmonary and pulmonary vascular diseases such as pulmonary hypertension, bronchopulmonary dysplasia, interstitial lung disease, respiratory failure, chronic cough and asthma. Her research is focused on the vascular changes seen in pulmonary hypertension, more specifically understanding the cellular characteristics of occlusive neointimal lesions, the abnormal cells that block pulmonary blood flow in pulmonary hypertension. In her most recent work, Dr. Steffes identified a subset of healthy vascular smooth muscle cells that are the cell of origin for the pathologic neointimal cells and a specific signaling pathway, that when blocked, inhibits the formation of neointimal lesions.
Dr. Steffes is currently employing advanced single cell sequencing technologies to further understand neointimal cells with the ultimate goal identifying new therapies for pulmonary hypertension, a fatal disease with no known cure. -
Gary K. Steinberg, MD, PhD
Bernard and Ronni Lacroute-William Randolph Hearst Professor of Neurosurgery and Neurosciences and Professor, by courtesy, of Neurology
Current Research and Scholarly InterestsOur laboratory investigates the pathophysiology and treatment of cerebral ischemia, and methods to restore neurologic function after stroke. Treatment strategies include brain hypothermia, stem cell transplantation and optogenetic stimulation. Our clinical research develops innovative surgical, endovascular and radiosurgical approaches for treating difficult intracranial aneurysms, complex vascular malformations and occlusive disease, including Moyamoya disease, as well as stem cell transplant.
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Lars Steinmetz
Dieter Schwarz Foundation Endowed Professor
Current Research and Scholarly InterestsWe apply diverse genomic approaches to understand how genetic variation affects health and disease by: 1) functional and mechanistic analyses of gene regulation, 2) studies of meiotic recombination and inheritance, 3) analyses of genetic and environmental interactions, and 4) characterization of diseases in human cells and model organisms. We integrate wet lab and computational genomic, transcriptomic, proteomic and metabolic approaches, and develop technologies to enable personalized medicine.
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Simon H. Stertzer, MD, FACC,FAHA,FACP
Professor of Medicine (Cardiovascular) at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsCoronary Angioplasty; Intramyocardial Stem cell delivery
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Frank E. Stockdale
Maureen Lyles D'Ambrogio Professor in the School of Medicine, Emeritus
Current Research and Scholarly InterestsLaboratory and clinical research in breast cancer ; Normal and abornal differentiation and growth
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Han Sun
Postdoctoral Scholar, Genetics
Biostatistician 2, Pediatrics - EndocrinologyBioHan had been a postdoc with Dr. Steinmetz at the genetics department for five years, working on both cancers and heart diseases, trying to understand the mechanisms linking from variants to disease phenotypes. This led to a few very interesting findings of aberrant splicing regulation, such as splicing-mediated readthrough stabilization (SRS), one more mechanism for oncogene activation in multiple types of cancers, and tissue-specific splicing of a mitochondrial inner membrane protein, suggesting a molecular connection between deficiency in energy-supplying and dilated cardiomyopathy.
After being a senior computational biologist with Dr. Gloyn, who has been dedicated to the research of type 2 diabetes for decades, Han switched to the field of this multifactorial metabolic disease. It did take some courage to make such a switch at his post-postdoc stage, however, Han has a consistent interest in studying PG&E, which is not pacific gas and electric nearby, but the interaction between phenotype, genotype, and environment. With years of hands-on experience in statistical modeling and the analysis of next-generation sequencing and mass spectrometry data, in addition to a good understanding of disease genetics, cancer biology, and systems biology, Han is highly confident that he will enjoy the adventure and contribute to our understanding of diabetes.
