School of Medicine
Showing 8,091-8,100 of 13,156 Results
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Amy Nava
Postdoctoral Scholar, Molecular and Cellular Physiology
BioMy long-term scientific ambition entails establishing an interdisciplinary and diverse laboratory primarily focused on countering antibiotic resistance. This objective comprises three central elements: elucidating the bacterial calcium transduction pathway, crafting innovative therapeutics to treat antibiotic-resistant deep tissue infections, and comprehending how calcium signaling stimulates bacterial pathogenesis mechanisms.
The foundation of my research experience supports the existence of calcium signal transduction pathways in bacteria. This conclusion aligns with various studies that drew indirect connections between calcium signaling and the regulation of other bacterial physiological processes, including virulence.
A thorough grasp of the mechanism by which calcium regulates multidrug-resistant functions, such as efflux, is a crucial stride toward mitigating the global crisis of antibiotic resistance. I am dedicated to contributing significantly to this path of exploration, ultimately driving impactful scientific development and healthcare improvement. -
Shaghayegh Navabpour
Postdoctoral Scholar, Pathology
Current Research and Scholarly InterestsMy research interests lie at the intersection of genetics and epigenetics, with a current focus on cancer and drug development. I am particularly interested in bifunctional small molecules, such as Transcriptional/Epigenetic Chemical Inducers of Proximity (TCIPs). My work now concentrates on designing, synthesizing, and testing new TCIPs that utilize various transcription factors or histone modifiers to target genes implicated in different types of cancer. Through this approach, I aim to develop innovative therapies that can more precisely and effectively combat cancer, especially to ease the treatment process for vulnerable patients, such as children and adolescents.
