School of Medicine
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Roeland Nusse
Virginia and Daniel K. Ludwig Professor of Cancer Research
Current Research and Scholarly InterestsOur laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding how Wnt signals lead to the proliferation of stem cells and on understanding Wnt signaling during repair and regeneration after tissue injury.
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Brian Anthony Nuyen, MD
Clinical Assistant Professor, Otolaryngology (Head and Neck Surgery)
BioBrian Nuyen, MD, is a board-certified otolaryngologist-head and neck surgeon and fellowship trained laryngologist who developed a keen interest and passion for head and neck gender affirmation for transgender/gender-nonconforming communities during his residency at Stanford Medicine. He completed his James Thomas, MD Voice Surgery Fellowship 2021-2022 in Portland, Oregon subspecializing in gender-affirming voice medicine and surgery. He was a visiting Fellow in Summer 2022 with Dr. Hyung-Tae Kim at the Yeson Voice Center in Seoul, South Korea with a focus on international perspectives on gender-affirming endoscopic vocal surgical innovation. Dr. Nuyen is a clinical assistant professor with the Stanford School of Medicine Department of Otolaryngology.
Dr. Nuyen specializes in managing vocal fold disorders, with a particular interest in gender affirmation voice surgery. Dr. Nuyen completed two fellowship programs focused on gender affirmation voice surgery.
He obtained his medical degree from the University of California, San Diego. Dr. Nuyen completed his residency at Stanford School of Medicine’s Department of Otolaryngology-Head and Neck Surgery.
Dr. Nuyen is a prolific author and researcher in his field. Multiple peer-reviewed journals have published his work and he has authored several textbook chapters. His recent articles focus on gender affirmation voice surgery. He also peer-reviews research manuscripts for the Journal of Voice. He has presented his insights and research at various medical conferences.
Dr. Nuyen speaks Spanish fluently. In his free time, he is an avid instrumental musician, singer, and swing dancer. -
Paul Nuyujukian
Assistant Professor of Bioengineering and of Neurosurgery
Current Research and Scholarly InterestsOur group explores neuroengineering and its application to both basic and clinical neuroscience. Our goal is to develop brain-machine interfaces as a platform technology for a variety of brain-related medical conditions including stroke and epilepsy.
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Peter Nonso Nwokoye
MD Student with Scholarly Concentration in Bioengineering, expected graduation Spring 2027
BioPeter Nonso Nwokoye was born and raised in Nigeria and graduated summa cum laude with dual Bachelor of Science degrees in Chemistry and Biology from Barry University. During his undergraduate studies, he worked on the synthesis of selective muscarinic receptor agonists and antagonists. In 2021, he was awarded the prestigious Gates Cambridge Scholarship to study at King's College, University of Cambridge. There, under the mentorship of Professor Anthony Davenport, he researched the expression and signaling of the apelin receptor and its endogenous agonists, Elabela and Apelin, in glioblastoma stem cells. This experience sparked his interest in developing novel methods to deorphanize orphan Class A GPCRs. After several months of intensive computational research, Peter developed a complex, multi-layered bioinformatic tool that he has used to identify likely endogenous ligands of orphan GPCRs, focusing on peptide ligands found in annotated uncharacterized open reading frames in the human genome. In his free time, he enjoys soccer, running, meditating, and teaching. Peter is excited about pursuing a career as a physician-scientist.
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Dáibhid Ó Maoiléidigh, PhD
Assistant Professor of Otolaryngology - Head & Neck Surgery (OHNS)
Current Research and Scholarly InterestsThe Ó Maoiléidigh group employs mathematical and computational approaches to better understand normal hearing and hearing impairment. Because complete restoration of auditory function by artificial devices or regenerative treatments will only be possible when experiments and computational modeling align, we work closely with experimental laboratories. Our goal is to understand contemporary experimental observations, to make experimentally testable predictions, and to motivate new experiments. We are pursuing several projects.
Hair-Bundle Mechanics
Auditory and balance organs rely on hair cells to convert mechanical vibrations into electrical signals for transmission to the brain. In response to the quietest sounds we can hear, the hair cell's mechanical sensor, the hair bundle, moves by less than one-billionth of a meter. To determine how this astounding sensitivity is possible, we construct computational models of hair-bundle mechanics. By comparing models with experimental observations, we are learning how a hair bundle's geometry, material properties, and ability to move spontaneously determine its function.
Cochlear Mechanics
The cochlea contains the auditory organ that houses the sensory hair cells in mammals. Vibrations in the cochlea arising from sound are amplified more than a thousandfold by the ear's active process. New experimental techniques have additionally revealed that the cochlea vibrates in a complex manner in response to sound. We use computational models to interpret these observations and to make hypotheses about how the cochlea works.
