Stanford University
Showing 1,101-1,200 of 1,483 Results
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Michael J Rosen, MD, MSCI
Stanford University Endowed Professor for Pediatric IBD and Celiac Disease
BioI am a pediatric gastroenterologist and physician scientist, who has been devoted to inflammatory bowel disease (IBD) research since beginning medical training over 20 years ago. I am also Director of the Stanford Center for Pediatric IBD and Celiac Disease. I have expertise crossing mucosal immunology and epithelial biology, formal training and experience in clinical and translational investigation with human biospecimens, and direct insight regarding the important clinical challenges caring for children with complicated IBD. My translational research program focuses on how the immune system regulates epithelial function in chronic intestinal inflammation as it relates to IBD. My clinical research program has focused on optimization of anti-TNF therapy in pediatric IBD, and in particular acute severe ulcerative colitis (ASUC). My laboratory has demonstrated a protective role for IL33, a cytokine that induces type 2 cytokines from T cells an innate lymphoid cells (ILCs), in acute oxazolone colitis through preservation of epithelial goblet cells and barrier function. In line with this finding, we have also shown in a large prospective patient cohort that mucosal expression of type 2 and type 17 immune response genes distinguishes ulcerative colitis (UC) from colon-only Crohn’s disease, and that type 2 gene expression is associated with superior clinical outcome in pediatric UC. We have now developed an organoid-immune cell in vitro culture system to demonstrate the ILC2-dependent mechanism through which IL33 induces goblet cell differentiation in the intestinal epithelium. I led the multicenter study Anti-TNF for Refractory Colitis in Hospitalized Children (ARCH) Study, which aims to establish determinants of anti-TNF response in pediatric ASUC and currently Co-Chair the Crohn's & Colitis Foundations Cohort for Pediatric Translational and Clinical Research in IBD (CAPTURE IBD) and PRO-KIIDS Pediatric IBD clinical research network.
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David Rosenthal
Professor of Pediatrics (Pediatric Cardiology)
On Partial Leave from 09/30/2024 To 11/01/2024Current Research and Scholarly InterestsResearch interests include the study of Heart Failure, Cardiomyopathy and ventricular dysfunction in children, from a clinical perspective. Investigations include clinical trials of medications, cardiac resynchronization, and mechanical circulatory support.
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Charlene Larson Rotandi
Associate Director of Fellowship Education, Pediatrics
BioI am the Associate Director of Fellowship Education in the Office of Pediatric Education. I have extensive experience managing fellowship and residency programs across leading academic institutions, including pediatric and graduate medical education roles. My background has equipped me with strong program administration, coordination, and leadership skills within medical education.
I am actively involved in the Association of Pediatric Program Directors (APPD) and currently serve on the Communications Work Group for the Coordinators’ Executive Committee. I have a strong track record of collaborating on initiatives focused on professional development, coordinator wellness, and program evaluation. My experience includes leading workshops and contributing to key areas such as curriculum development, assessment, and program coordinator professional development. Additionally, I am passionate about mentoring and continuously seek opportunities to collaborate and support others in the field.
Outside of graduate medical education, I am the mother of a very active and curious twelve-year-old. I also enjoy spending time with my family exploring the Bay Area, hiking, cooking, and enjoying food, wine, and the vibrant arts culture. After a brief stint as a pastry cook, I love to cook and bake with my son. Additionally, I continue to be involved in my alma mater, Vassar College, by co-chairing the Vassar Alumnae/i Admissions Program in San Francisco. -
Stephen J. Roth
Professor of Pediatrics (Cardiology)
On Partial Leave from 09/16/2024 To 10/31/2024Current Research and Scholarly InterestsRandomized Therapeutic Trials in Pediatric Heart Disease, NIH/U01 GrantNo. HL68285 2001-2006.
Heparin and the Reduction of Thrombosis (HART) Study. Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006.
A Pilot Trial fo B-type Natriuretic Peptide for Promotion of Urine Output in Diuretic-Resistant Infants Following Cardiovascular Surgery.Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006. -
Christopher John Russell
Associate Professor of Pediatrics (Hospital Medicine)
BioDr. Russell is an Associate Professor of Pediatrics in the Division of Pediatric Hospital Medicine and a board-certified academic pediatric hospitalist at Lucile Packard Children’s Hospital. His clinical responsibilities include caring for children hospitalized for a variety of illnesses. His research focuses on developing evidence-based care for hospitalized children with medical complexity, including acute respiratory infections (such as pneumonia and bacterial tracheitis). His research efforts have been recognized through receipt of the University of Southern California’s Clinical and Translational Science Institute’s KL2 Mentored Research Career Development Award (2014-16), the Academic Pediatric Association’s Young Investigator Award (2015-16), the NIH Loan Repayment Program (2017-2021) and a large grant from the Gerber Foundation (2020-2022). In August 2021, he received a five-year R01 award from the Agency for Healthcare Research and Quality to study bacterial respiratory infections in children with tracheostomy. Outside of his clinical and research responsibilities, Dr. Russell focuses on research mentorship of medical students, pediatric residents, and pediatric hospital medicine fellows as well as improving representation of underrepresented minorities in medicine throughout the continuum of physician training. Dr. Russell is the chair of the Academic Pediatric Association’s Membership, Diversity, and Inclusion Committee and is on the Executive Committee for the Pediatric Research in Inpatient Settings research network. Dr. Russell is active in the AAP and currently serves as an Associate Editor for the journal Hospital Pediatrics.
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Raya Saab
Lindhard Family Professor of Pediatric Cancer Biology
BioOur laboratory focuses on investigating molecular mechanisms of oncogene-induced tumorigenesis and tumor suppressor pathways, and oncogenic signaling in the pediatric solid tumor rhabdomyosarcoma. Our earlier work identified the tumor suppressors p53 and p18Ink4c as inhibitors of Cyclin D1-driven tumorigenesis in a pineoblastoma model, through senescence induction, and highlighted distinct roles for the the RB and p53 pathways in induction and maintenance of oncogene-induced senescence. We also identified CDK2 as a potential target for inducing senescence in premalignant lesions to inhibit tumor progression.
Our current focus is on studying oncogenic signaling and tumor suppression in the childhood tumor rhabdomyosarcoma, to identify key mediators of invasion and metastasis, which is the most common cause of treatment failure clinically. We use preclinical in vitro and in vivo models, including murine and human cell lines, and mouse models of disease.
We have recently uncovered a paracrine role for rhabdomyosarcoma-secreted exosomes in impacting biology of stromal cells. Rhabdomyosarcoma-derived exosomes carry specific miRNA cargo that imparts an invasive and migratory phenotype on normal recipient fibroblasts, and proteomic analysis revealed specific and unique pathways relevant to the two different molecular rhabdomyosarcoma subtypes that are driven by distinct oncogenic pathways. We identified that the driver oncogene in fusion-positive rhabdomyosarcoma, PAX3-FOXO1, modulates exosome cargo to promote invasion, migration, and angiogenic properties, and identified specific microRNA and protein cargo acting as effectors of PAX3-FOXO1 exosome-mediated signaling, including modulation of oxidative stress response and cell survival signaling.
Our ongoing work is focused on interrogating specific paracrine signaling pathways and molecular mechanisms of metastatic disease progression in rhabdomyosarcoma, for potential therapeutic targeting. -
Rebecca Saenz
Clinical Assistant Professor, Pediatrics - Immunology and Allergy
Current Research and Scholarly InterestsAllergy, Immunology, Bioengineering and Biodesign
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Julien Sage
Elaine and John Chambers Professor of Pediatric Cancer and Professor of Genetics
Current Research and Scholarly InterestsWe investigate the mechanisms by which normal cells become tumor cells, and we combine genetics, genomics, and proteomics approaches to investigate the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells and to identify novel therapeutic targets in cancer cells.
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Gaurav Saini
Life Science Research Professional, Pediatrics - Cardiology
Current Role at StanfordLife Science Research Professional 1
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Debbie C. Sakaguchi Sakai
Clinical Professor, Pediatrics
Current Research and Scholarly InterestsMedical education, shared decision making, resuscitation.
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Kathleen M. Sakamoto
Shelagh Galligan Professor in the School of Medicine
Current Research and Scholarly InterestsMy research focuses on the molecular pathways that regulate normal and aberrant blood cell development, including acute leukemia and bone marrow failure syndromes. We are also studying novel drugs for treatment of cancer.
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Christy Sandborg
Professor of Pediatrics (Rheumatology), Emerita
Current Research and Scholarly InterestsThe major emphasis of my work in the past 2 decades has been focused on the future of academic pediatrics and pediatric rheumatology through providing training, research opportunities and environments to nurture and challenge future pediatric rheumatologists and subspecialists. In parallel in the last decade, my scope has included to workforce and physician wellbring, patient and family centered care--and more recently, diversity, equity and inclusion, and health equity.
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Kelly Corbett Sanders
Clinical Instructor, Pediatrics - General Pediatrics
BioDr. Kelly Sanders is a Stanford pediatrician and the Technical Lead of the Pandemic Response Initiative at the University of California San Francisco (UCSF) Institute for Global Health Sciences. She completed a Master of Science and Doctor of Medicine at the University of San Francisco, California, and pediatrics residency training at Lucile Packard Children’s Hospital at Stanford University. Before pursuing a career as a physician, Dr. Sanders worked with the UCSF Global Health Group’s Malaria Elimination Initiative (MEI) on operational research projects with partner countries, as well as on developing communications and advocacy priorities with MEI and global partners. Previously, she worked with the UCSF Institute for Global Health Sciences, supporting the creation of the Consortium of Universities for Global Health and the UC Global Health Institute. In addition to her work at UCSF, Dr. Sanders practices clinically as a pediatrician at Stanford University, Palo Alto Medical Foundation and Santa Clara Valley Medical Center.
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Lee M. Sanders, MD, MPH
Professor of Pediatrics (General Pediatrics), of Health Policy and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsI conduct interdisciplinary research to understand literacy as potentially modifiable lens for addressing maternal and child health disparities from birth through early adulthood. Applying mixed methods approaches (health-services, epidemiology, ethnography), I have been principal investigator on extramurally-funded research projects (NIH, PCORI, FDA) that aim to examine "natural experiments" in policy and/or to design, implement and test novel system-level interventions.
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Meera N. Sankar
Clinical Professor, Pediatrics - Neonatal and Developmental Medicine
Current Research and Scholarly InterestsPDA in preterm
Transcutaneous bilirubin use in the NICU
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Chethan Sarabu
Clinical Assistant Professor, Pediatrics - General Pediatrics
BioChethan Sarabu, MD trained in landscape architecture, pediatrics, and clinical informatics builds anastomoses across these fields to design healthier environments and systems. He is a clinical assistant professor of Pediatrics at Stanford Medicine, Director of Clinical Informatics at Sharecare. Across these roles, he works on designing and implementing a wide array of innovations ranging from patient portals, EHR transformation, virtual clinical trials, and A.I. driven digital biomarkers, to health information policy initiatives all through a lens of health equity and patient privacy.
He takes care of patients in a community based academic general pediatrics practice at the Gardner Packard Clinic, a Federally Qualified Health Center, where he has also assisted with EHR implementation and transition. He cares deeply on involving children in their own care and strongly focused on protecting the privacy and confidentiality of adolescents in an increasingly digital healthcare system. He helped to form and co-chair the national workgroup, Shift which has been working to promote equitable interoperability.
Drawing on his background in landscape architecture, Chethan implements and researches nature based health solutions in collaboration with the Stanford Natural Capital Project. Finally, further exploring the role of environment and human health, he is shaping the emergent field of climate health informatics. -
David Alex Sarno
Adjunct Lecturer, Pediatrics - Cardiology
BioDavid Sarno is a lecturer in the Department of Pediatrics at the school of medicine, specializing in virtual reality-based education. David founded Lighthaus Inc., a VR education company in 2013 while a John S. Knight journalism fellow at Stanford. Before that, David was a technology journalist at the Los Angeles Times for seven years. He holds an MFA in Creative Writing from the University of Iowa and a B.A. in Computer Science from Yale University.
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Clea Sarnquist, DrPH, MPH
Clinical Associate Professor, Pediatrics - Infectious Diseases
Clinical Associate Professor (By courtesy), Epidemiology and Population HealthBioDr. Sarnquist focuses on applied teaching and research on the development, implementation and evaluation of interventions to decrease gender-based violence and prevent HIV infection, especially among adolescents and children. She is particularly interested in rights-based approaches that tackle the complex interplay of factors that lead to poor health for many children and families. All of her work is applied, with direct links health practice and policy, and usually performed in conjunction with non-governmental organization and government partners. She works both globally and in the U.S., with a focus on sub-Saharan Africa. She is also a medical educator, directing the scholarly concentrations program of the pediatric residency at Stanford, and co-directing the global health concentration for residents
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Andrew Saunders
Clinical Associate Professor, Pediatrics
BioDr. Saunders (he/him) is a Clinical Associate Professor of Pediatrics, and the medical director of the Pediatric Hospitalist Program at SHC Tri-Valley. His academic interests include diversity, equity, and inclusion in medicine; LGBTQIA+ health; ethics in technology; global health; medical education; public health; and physician wellness.
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Michael Scahill
Clinical Assistant Professor, Pediatrics - Neonatal and Developmental Medicine
BioOn a trip to Mozambique while in med school here at Stanford, I saw the power of market interventions to improve population health. In Pediatric Leadership for the Underserved residency at UCSF, I helped Jacaranda Health establish their pediatric clinic in Nairobi. Now, I split my time between the Stanford NICU and Virta, where I direct the digitally delivered diabetes reversal clinic.
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David Scheinker
Clinical Professor, Pediatrics - Endocrinology and Diabetes
BioDavid Scheinker is the Executive Director of Systems Design and Collaborative Research at the Stanford Lucile Packard Children's Hospital. He is the Founder and Director of SURF Stanford Medicine, a group that brings together students and faculty from the university with physicians, nurses, and administrators from the hospitals. SURF has implemented and published dozens of projects demonstrating improvements to the quality and efficiency of care. His areas of focus include clinical care delivery, technical improvements to hospital operations, sensor-based and algorithm-enabled telemedicine, and the socioeconomic factors that shape healthcare cost and quality.
Before coming to Stanford, he was a Joint Research Fellow at The MIT Sloan School of Management and Massachusetts General Hospital. He received a PhD in theoretical math from The University of California San Diego under Jim Agler. He advises Carta Healthcare, a healthcare analytics company started by former students. -
Noelle Schlenk
Rsch Data Analyst 1, Pediatrics - Rheumatology
BioNoelle is a Research Data Analyst for the Immune Behavioral Health Clinic / research team. She applies her expertise in statistics and bioinformatics to investigate genetic components of Pediatric Acute-onset Neuropsychiatric Syndrome (PANS).
Noelle holds a master's degree in Ecology & Evolutionary Biology from the University of Kansas. -
Alan Schroeder
Clinical Professor, Pediatrics
BioDr. Schroeder is the associate chief for research in the division of pediatric hospital medicine at Lucile Packard Children’s Hospital Stanford, and a clinical professor in the division of hospital medicine and the division of critical care. His research interests focus on identifying areas where we can “safely do less” in healthcare, striving to ensure that children get the healthcare that they need while avoiding excessive tests and treatments that only cause harm. Dr. Schroeder is currently involved in multiple projects involving common conditions and interventions in pediatrics. He serves as the Stanford PI for PEDSNet and is an Associate Editor for the journal Hospital Pediatrics. At Stanford he co-leads the residency clinical research scholarly concentration and the faculty Clinical Research Peer Scholarship Community. Dr. Schroeder provides clinical care for children in the PICU and the pediatric ward.
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Liora Schultz
Clinical Assistant Professor, Pediatrics - Hematology & Oncology
BioI am currently postdoctoral research fellow pursuing immunotherapy research in the oncology department at Stanford University. My clinical training as a pediatric hematology oncology fellow at Memorial Sloan Kettering Cancer Center highlighted the desperate need for novel therapeutic options for a subtype of aggressive pediatric leukemia, Acute Myeloid Leukemia (AML). Despite our best standard of care for AML, long term survival rates range from 50-60% with an unacceptably high relapse rate of 40%. The urgent need for novel treatments inspired me to pursue a research project in adoptive immunotherapy, genetically modifying Tcells to express artificial T cell receptors, termed chimeric antigen receptors (CARs), that target AML specific antigens. In parallel to my clinical training, I constructed an AML specific CAR and demonstrated its ability to redirect T cell function mediating eradication of AML cells. As the field of CAR therapy rapidly advances, novel methods to optimize this therapeutic modality are imperative. To this end, supported by research demonstrating superior antitumor function of naïve derived effector T cells compared to central memory derived effector T cells, I am investigating whether preferential modification of naïve T cells to express CARs will generate a T cell subpopulation with increased efficacy. Consolidating my clinical and research experiences within highly academic institutes allows me to synthesize my pursuit of scientific rigor and commitment to the field of oncology, with a mission to achieve productive research and translatable results.
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Jennifer Chie Schymick
Clinical Assistant Professor (Affiliated), Pediatrics - Genetics
BioPROFESSIONAL EDUCATION
∗ Medical Genetics Fellowship Stanford University (2018-2020)
∗ General Internal Medicine Residency University of Toronto (2013-2018)
∗ M.D. University of California Irvine (2009-2013)
∗ Ph.D. Oxford University & National Institutes of Health (2005-2009)
∗ B.Sc. Massachusetts Institute of Technology (1998-2002) -
Christopher Thomas Scott, PhD
Sr Research Scholar, Pediatrics - Center for Biomedical Ethics
Current Research and Scholarly InterestsMy research focuses on the political, legal, ethical and economic impacts of stem cell research. Topics include: embryonic and adult stem cell research and clinical trials, stem cell banking, human-animal chimeras; cell and gamete donation; international perspectives of bioethics; global economic impacts; national and state regulatory policy, stem cell entrepreneurship, intellectual property and offshore stem cell transplants.
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Talal Seddik
Clinical Associate Professor, Pediatrics - Infectious Diseases
Current Research and Scholarly InterestsTalal Seddik is a member of the Collaborative Antiviral Study Group. He is the key site investigator at the Stanford site for the following multicenter studies:
1) DMID 19-0026 Enterovirus Study
Neonatal Enterovirus and Human Parechovirus Viral Sepsis: Natural History and Predictors of Morbidity and Mortality
This study will be the first large, multi-state prospective assessment of the viral causes of neonatal sepsis conducted. The main reason for this research study is to get a better understanding of what causes neonatal viral sepsis and to assess the impact of the infection on the babies’ health. Viruses called enterovirus (EV) or human parechovirus (HPeV) are very common in the population and can cause neonatal viral sepsis. By gaining a better understanding of the condition, we hope this information can be used to guide diagnosis and treatment of babies with neonatal viral sepsis in the future.
This study is actively enrolling subjects
2) DMID 19-0005 Acute Flaccid Myelitis (AFM) Study
A Prospective Study of Acute Flaccid Myelitis (AFM) to Define Natural History, Risk Factors and Pathogenetic Mechanisms
Patients with suspected AFM (onset of flaccid limb weakness within the previous 30 days) are eligible to enroll in the study. Investigators will assess participants at four-time points within the first month of enrollment and will ask participants to return for additional follow up visits at 3 months, 7 months and 1 year. Neurologic improvements will be tracked over time, and samples will be collected and stored in a biorepository for use in future research studies. Household contacts, such as siblings, will be eligible to participate in the study as a control or comparison group.
This study is actively enrolling subjects. -
Zachary M. Sellers, MD, PhD
Adjunct Professor, Pediatrics - Gastroenterology
BioDr. Sellers is a pediatric physician-scientist and research and clinical development consultant. As a pediatric gastroenterologist and ion channel physiologist, Dr. Sellers' work in academia and pharma over the last 20 years has focused on improving the lives of individuals with complex and rare diseases through providing cutting-edge clinical care and advancing research and drug development. Dr. Sellers previously led a basic and translational research laboratory at Stanford, focused on epithelial ion transport and acid-base regulation using a variety of human and animal models. He is a firm believer in the exponential impact of team science and is adept working in multi-disciplinary and cross-functional teams. He seeks out strategic partnerships and opportunities that can leverage his expertise and leadership to advance innovative therapies for areas of high unmet need and to support the development of the next generation of physician-scientists. Dr. Sellers received his BS (Animal Physiology and Neuroscience) and BA (Japanese Studies) from the University of California. San Diego, his MD and PhD (Molecular and Integrative Physiology) from the University of Illinois at Urbana-Champaign, and was trained in Pediatrics and Pediatric Gastroenterology, Hepatology, and Nutrition at Stanford, where he was previously a faculty member and attending physician. He held multiple leadership positions at Stanford, including Associate Chief of Research in Gastroenterology, Director of the Stanford Children's Pancreas Program, Lead Gastroenterologist for the CF Program, Director of the CFTR Phenotyping and Theratyping Program, and Physician-Scientist Advisor for the Pediatrics Residency Program.
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Zachary Aaron Sexton
Postdoctoral Scholar, Cardiology
BioFocused on understanding cardiovascular physiology, disease, and tissue engineering through stem cell biology and hemodynamics. Specializes in 3D extrusion bioprinting and computational fluid dynamics (though an open-source software platform SimVascular) to improve tissue engineering strategies for the successful development of cardiac tissues for disease modeling and therapeutic solutions.
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Ami J. Shah
Clinical Professor, Pediatrics - Stem Cell Transplantation
BioI joined Stanford University in 2015 as a Clinical Professor of Pediatrics in the Division of Hematology/ Oncology, Stem Cell Transplantation and Regenerative Medicine, having completed my training in Pediatric Hematology/ Oncology at Childrens Hospital Los Angeles. My areas of clinical expertise have been in the areas of transplantation for immune deficiencies and immune reconstitution post HSCT. I have been actively involved with the care and treatment of children with primary immune deficiencies and work with the Primary Immune Deficiencies Consortium (PIDTC). I am very interested in cellular therapies as a treatment modality for rare genetic diseases. I currently am the PI for several gene therapy trials at Stanford for various disorders including cerebral adrenoleukodystrophy (cALD), Sickle Cell Anemia, Thalassemia and Pyruvate Kinase Deficiency. My other main areas of research have been in studying the late effects of patients following stem cell transplantation, in specific the neurocognitive function post HSCT. I have been involved with several national committees addressing the late effects of HSCT within the ASBMT and COG.
In addition to my research work in stem cell transplantation, I have been actively involved with mentorship and graduate medical education. I am currently the Program Director for the Hematology/ Oncology Fellowship and serve as a mentor through the Pediatric Mentoring Group. -
Manish I. Shah, MD, MS
Professor of Emergency Medicine (Pediatrics) and, by courtesy, of Pediatrics (Hospital Medicine)
BioI have dedicated my career to improving pediatric prehospital care on local, statewide, national, and international levels through research, education, and advocacy. My primary research interest focuses on integration of pediatric evidence into emergency medical services (EMS) systems. I serve on the Executive Committee of the Pediatric Emergency Care Applied Research Network (PECARN) as the nodal Principal Investigator (PI) for the Charlotte, Houston, and Milwaukee Prehospital (CHaMP) research node. In addition, I am the PI for the Pediatric Dose Optimization for Seizures in EMS (PediDOSE) clinical trial and co-investigator for the Pediatric Prehospital Airway Resuscitation Trial (Pedi-PART). As an educational researcher, I have obtained several grants to produce an online EMS educational resource for physicians, create the Pediatric Simulation Training of Emergency Prehospital Providers (PediSTEPPs) program, and study the implementation of an EMS training curriculum for the Botswana Ministry of Health. As an EMS advocate, I led the Prehospital and State Partnership domains for the national EMS for Children (EMSC) Innovation and Improvement Center (EIIC), served as an appointed member of the National Emergency Medical Services Advisory Council (NEMSAC), chaired the EMS subcommittee for the American Academy of Pediatrics Section of Emergency Medicine, and directed the EMSC State Partnership in Texas. I have published policy on pediatric readiness in EMS systems and co-chaired the workgroup that created the first-ever national assessment of pediatric readiness of EMS systems for the National Prehospital Pediatric Readiness Project (PPRP).
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Mona D. Shah, MD, MBA
Adjunct Clinical Associate Professor, Pediatrics - Hematology & Oncology
BioDr. Mona Shah is a pediatric hematologist-oncologist, who earned her MD degree at the University of Maryland in 2001. She completed both her categorical pediatrics and global health residencies in 2004, followed by a pediatric hematology-oncology fellowship in 2007. She earned her MS in Clinical Investigation as part of the Clinical Scientist Training Program (CSTP) at Baylor College of Medicine in 2011, and more recently, completed an Executive MBA at Rice University Jones School of Business in 2018.
Dr. Shah was an Associate Professor at Baylor College of Medicine (2007 - 2020) in both Pediatrics and Medicine, local site PI on a number of pediatric hemostasis/thrombosis clinical trials, and spent 10 years as an Associate Medical Director of Clinical Operations, Quality, and Safety at Texas Children’s Hospital, Houston, TX.
Dr. Shah joined Genentech (a Member of the Roche Group)’s Rare Blood Disorders Franchise (Product Development - Oncology-Hematology) in February 2020, quickly advancing to Lead Medical Director, where she served as Medical Monitor for 2 Phase III Clinical Trials (crovalimab in atypical hemolytic uremic syndrome, aHUS). She was also engaged with the Renal Franchise (I2O) in developing crovalimab in Lupus Nephritis (Phase I & II Clinical Trials in development), and with Human Factors/Pediatric Formulations Working Group on autoinjector devices and oral formulations.
After completing a rotation in Early Development Safety (EDS), she was promoted to Senior Medical Safety Director in Late Stage Product Development, and was appointed Safety Strategy Lead for giredestrant in early and metastatic breast, ovarian, and endometrial cancer global clinical trials. She has experience in innovative study designs (adaptive/multi-drug), with FDA/EMA pediatric investigational plans, and health authority interactions. In June 2023, she was appointed Pediatric Safety Lead, in collaboration with the iPODD Team, supporting safety for pediatric indications and devices, and serves as the Co-Chair of the Pediatric Safety Expert Group.
Dr. Shah has kept and completed a bucket list since she was 7 years old (keeps growing): Running wild bouldering/rock climbing as a child in the Shenandoah/Blue Ridge Mountains, swimming with dolphins/piranhas in the Amazon, climbing inside a volcano caldera in Iceland, snorkeling the Great Barrier Reef ... have passport/will travel!
Since July 2022, she has joined Stanford University School of Medicine, as an Adjunct Clinical Associate Professor in the Department of Pediatrics, Division of Hematology-Oncology, where she enjoys teaching MSII students, and at the bedside in the Lucille Packard Bass Center Hematology Clinic. Dr. Shah enjoys free time in her new home base near San Francisco, where she hosts her visiting parents, friends, and extended family. -
Sejal Shah
Clinical Assistant Professor, Pediatrics - Endocrinology and Diabetes
Current Research and Scholarly InterestsMy primary research interest is evaluating whether vitamin D supplementation can positively affect consequences of the metabolic syndrome in overweight and obese adolescents. Other research interests include evaluating the efficacy and biochemical profiles of various types of estrogen replacement in adolescent females.
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Paul Sharek MD, MPH
Professor of Pediatrics (Hospital Medicine) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsResearch interests centered on hospital based quality of care improvement, and in particular pediatric patient safety. Areas of recent interest include developing practical tools to more accurately identify adverse medical events and to establish national rates of these adverse events. Additional areas of interest focus on developing the processes and systems to decrease the frequency of adverse drug events and adverse medical events at Children's hospitals in North America
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Aditi Sharma
Basic Life Research Scientist, Pediatrics - General Pediatrics
Current Role at StanfordResearch Scientist
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Seth Andrew Sharp
Postdoctoral Scholar, Endocrinology and Metabolism
BioSeth is a Larry L. Hillblom Postdoctoral Fellow in the Translational Genomics of Diabetes laboratory under Dr. Anna Gloyn with co-mentorship in statistical and population genetics from Dr. Manuel Rivas. Seth completed a B.E. in Applied Mathematics before studying a PhD at the University of Exeter with Drs. Richard Oram and Michael Weedon in which he spent significant time at the Pacific Northwest Research Institute developing new statistical models for polygenic risk scores to predict, screen and understand Type 1 diabetes and other autoimmune disorders with screening expert Dr. William Hagopian. Seth was further seconded to the Alan Turing Institute in London where he used deep learning methods to develop neonatal blood spot polygenic risk screening panels. His postdoctoral studies at Stanford now focus on applying "GWAS-in-a-Dish' and "Polygenic Risk Score to Function (PRS2F)' approaches with rich cellular phenotyping from human donor islets to understand the molecular determinants of impaired insulin secretion in diabetes. He is involved in a number of national human islet research networks and gene-perturbation screen efforts aimed at better understanding diabetes, as well as clinical translation studies at Stanford aimed at improving precision medicine approaches to diabetes.
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Gary M. Shaw
NICU Nurses Professor and Professor (Research), by courtesy, of Epidemiology and Population Health and of Obstetrics and Gynecology (Maternal Fetal Medicine)
Current Research and Scholarly InterestsPrimary research interests include 1) epidemiology of birth defects, 2) gene-environment approaches to perinatal outcomes, and 3) nutrition and reproductive outcomes.
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Xinshu She
Clinical Associate Professor, Pediatrics
Clinical Associate Professor, Pediatrics - General PediatricsCurrent Research and Scholarly InterestsMy current interests include global mental health promotion in underserved pediatric populations, including refugee health in US-Mexico borders, minority mental health in the US, and parental mental health in low-middle-income countries. I am also interested in physician wellness and Diversity and Inclusion.
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Andrew Young Shin
Clinical Professor, Pediatrics - Cardiology
Current Research and Scholarly InterestsSURF PROGRAM
The SURF program is an innovative collaboration between LPCH, Stanford University Hospital and the Stanford School of Engineering. The program has focused on improving quality and safety of patient care, improving hospital operations and promoting clinical effectiveness utilizing contemporary technologies such as machine learning, mathematical optimization, simulation and a variety of statistical, probabilistic and computational tools. The program has 2 independent funding mechanism to primarily improve patient care/hospital operations and improve academics for faculty within the department of Pediatrics at LPCH.
https://surf.stanford.edu/
CLINICAL EFFECTIVENESS
The Clinical Effectiveness (CE) Program is a funded program that aims to understand and improve unnecessary variation in healthcare delivery in order to optimize quality of care and reduce wasteful expenditures. The CE program has developed innovative programs such as Target Based Care, an award-winning intervention to reduce variation in hospital length of stay and currently a multi-center trial involving more than 20 hospitals in North America. In 2016, the CE program included the first CE fellowship program in a pediatric training program with 3 cycles of graduates. The CE program is supported by LPCH and a philanthropic gift by Susan Choe and Thomas Tobiason.