Vice Provost and Dean of Research
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Tian Yi Zhang, MD, PhD
Assistant Professor of Medicine (Hematology)
BioDr. Zhang is a board-certified hematologist. She is also an assistant professor of hematology at Stanford University School of Medicine. In addition to her medical degree, she holds a PhD in cellular and molecular immunology.
In her clinical practice, she treats patients with all forms of hematological malignancies, offering specialized expertise in acute myeloid leukemia, including therapy-resistant cases. For each patient, she develops a personalized care plan encompassing novel treatment options.
Her research activities include conducting early phase clinical trials, investigator initiated clinical trials (IITs), studying the immune repertoire in patients with myeloid malignancies, and exploring cholesterol metabolic dependencies of acute myeloid leukemia (AML).
She was the recipient of an A.P. Giannini Foundation fellowship award, which supports innovative research. The award helped fund Dr. Zhang’s study of how AML cells interact with other cells in bone marrow. A significant finding confirmed that AML cells secrete a protein that suppresses the production of red blood cells, the same protein that causes inflammation in disorders such as rheumatoid arthritis and Crohn’s disease.
Her many other honors include the National Cancer Institute Career Development (K08) Award, the American Society of Hematology (ASH) Research Training Award for Fellows, Stanford Cancer Institute - American Cancer Society (SCI-ACS) Pilot Grant and Best ASH Abstract Award two years in a row. She also has earned recognition from the National Institutes of Health and American College of Physicians.
She has published her research findings on topics such as advanced therapy for high-risk myelodysplastic syndromes and reversal of bone marrow failure induced by AML. Her work has appeared in Leukemia & Lymphoma, Science Translational Medicine, Cancer Research, the Journal of Clinical Investigation, Journal of Immunology, and elsewhere.
Dr. Zhang is a member of the American Association of Cancer Research and American Society of Hematology. She advises and mentors Stanford medical students, residents and fellows. She delivers invited lectures to faculty and fellows. In addition, she has been an invited speaker on the topic of acute myeloid leukemia at the Association of Northern California Oncologists Update on Hematological Malignancies. -
Yu Zhang
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)
BioDr. Yu Zhang's research operates at the intersection of AI, translational neuroscience, and precision medicine. His work focuses on unraveling the complex neurobiological mechanisms underlying cognitive deficits, behavioral dysfunctions, and therapeutic responses in mental health disorders. By integrating advanced machine learning techniques with multimodal brain imaging modalities (e.g., fMRI, DTI, EEG), Dr. Zhang aims to identify neural signatures that reveal the heterogeneity of mental disorders across individuals. A central goal of his research is the development and validation of robust neurobiomarkers to improve diagnostic accuracy, refine prognostic assessments, and guide personalized treatment strategies. His work systematically characterizes brain function and dysfunction to optimize therapeutic interventions, including pharmacological treatments, psychotherapy, and neurostimulation. He is particularly focused on conditions such as Alzheimer’s disease and related dimentia, mood disorders, and neurodevelopmental disorders (e.g., ADHD, ASD), where individualized approaches are essential for improving patient outcomes.
Dr. Zhang has received several grants including the R01, R21, and Alzheimer's Association AARG grant. Beyond foundational research, Dr. Zhang is committed to bridging the gap between computational innovation and clinical application. By collaborating with clinicians, neuroscientists, and engineers, he strives to translate data-driven insights into actionable tools for real-world healthcare settings. His long-term vision is to enable mental health diagnostics and treatment to be guided by objective, biologically grounded biomarkers, thereby enhancing quality of life and long-term outcomes for individuals with psychiatric and neurological conditions.
The Stanford Precision NeuroIntelligence (SPNI) Lab, led by Dr. Zhang, is dedicated to advancing research in AI-driven neuroimaging and precision psychiatry. The lab develops and applies cutting-edge machine learning and deep learning methods to uncover neurobiological mechanisms associated with cognitive and behavioral dysfunctions, as well as treatment responses in mental health conditions. Its mission is to identify translational biomarkers that support precision diagnosis, prognosis, and targeted interventions for mood disorders, neurodevelopmental disorders, and neurodegenerative diseases. -
Heng Zhao
Member, Wu Tsai Neurosciences Institute
Current Research and Scholarly InterestsMy lab is focused on developing novel therapeutic methods against stroke using rodent models. We study protective effect of postconditioning, preconditioning and mild hypothermia. The rationale for studying three means of neuroprotection is that we may discover mechanisms that these treatments have in common. Conversely, if they have differing mechanisms, we will be able to offer more than one treatment for stroke and increase a patients chance for recovery.