Bio-X
Showing 651-700 of 1,076 Results
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Jennifer A McNab
Associate Professor (Research) of Radiology (Radiological Sciences Laboratory)
Current Research and Scholarly InterestsMy research is focused on developing magnetic resonance imaging (MRI) methods that probe brain tissue microstructure. This requires new MRI contrast mechanisms, strategic encoding and reconstruction schemes, physiological monitoring, brain tissue modeling and validation. Applications of these methods include neuronavigation, neurosurgical planning and the development of improved biomarkers for brain development, degeneration, disease and injury.
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Kimford Meador, MD
Professor of Neurology and Neurological Sciences (Adult Neurology)
BioDr. Meador is a Professor of Neurology and Neurosciences at Stanford University, and Clinical Director, Stanford Comprehensive Epilepsy Center. Dr. Meador graduated from the Georgia Institute of Technology in Applied Biology (with high honor) and received his MD from the Medical College of Georgia. After an internship at the University of Virginia and service as an officer in the Public Health Corps, he completed a residency in Neurology at the Medical College of Georgia and a fellowship in Behavioral Neurology at the University of Florida. Dr. Meador joined the faculty at the Medical College of Georgia (1984-2002) where he became the Charbonnier Professor of Neurology. He was the Chair of Neurology at Georgetown University (2002-2004), the Melvin Greer Professor of Neurology and Neuroscience at the University of Florida (2004-2008) where he served as Director of Epilepsy Program and Director of the Clinical Alzheimer Research Program, and Professor of Neurology and Pediatrics at Emory University (2008-2013) where he served as Director of Epilepsy and of Clinical Neurocience Research. He joined the faculty of Stanford University in 2013. Dr. Meador has authored over 400 peer-reviewed publications. His research interests include: cognitive mechanisms (e.g., memory and attention); cerebral lateralization; pharmacology and physiology of cognition; mechanisms of perception, consciousness and memory; EEG; epilepsy; epilepsy and pregnancy; preoperative evaluation for epilepsy surgery; intracarotid amobarbital procedure (i.e., Wada test); functional imaging; therapeutic drug trials; neurodevelopmental effects of antiepileptic drugs; psychoimmunology; behavioral disorders (e.g., aphasia, neglect, dementia); and neuropsychiatric disorders. Dr. Meador has served as the PI for a long running NIH multicenter study of pregnancy outcomes in women with epilepsy and their children. Dr. Meador has served on the editorial boards for Clinical Neurophysiology, Epilepsy and Behavior, Epilepsy Currents, Journal of Clinical Neurophysiology, Neurology, Cognitive and Behavioral Neurology, and Epilepsy.com. His honors include Resident Teaching Award Medical College of Georgia; Outstanding Young Faculty Award in Clinical Sciences Medical College of Georgia; Distinguished Faculty Award for Clinical Research Medical College of Georgia Lawrence C. McHenry History Award American Academy of Neurology; Dreifuss Abstract Award American Epilepsy Society; Fellow of the American Neurological Association; Diplomat of American Neurologic Association; past Chair of the Section of Behavioral Neurology of American Academy of Neurology; past President of Society for Cognitive and Behavioral Neurology; past President of the Society for Behavioral & Cognitive Neurology; past President of the Southern EEG & Epilepsy Society; ranking in the top 10 experts in epilepsy worldwide by Expertscape; Distinguished Alumnus Award for Professional Achievement, Medical College of Georgia, Georgia Regents University 2015; American Epilepsy Society Clinical Research Award; and named award by the American Epilepsy Society: “Kimford J. Meador Research in Women with Epilepsy Award,” and ranked in the top 500 neuroscientist in the world and top 300 in USA by Research.com in 2022.
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Elizabeth Mellins
Member, Bio-X
Current Research and Scholarly InterestsMolecular mechanisms and intracellular pathways of MHC class II antigen processing and presentation, with a focus on B cells; mechanisms underlying HLA allele association with disease; disease mechanisms in systemic juvenile idiopathic arthritis, including an HLA-linked complication; monocytes as drivers or suppressors of auto-inflammation in systemic juvenile idiopathic arthritis and pediatric acute neuropsychiatric syndrome.
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Nicholas Melosh
Professor of Materials Science and Engineering
BioThe Melosh group explores how to apply new methods from the semiconductor and self-assembly fields to important problems in biology, materials, and energy. We think about how to rationally design engineered interfaces to enhance communication with biological cells and tissues, or to improve energy conversion and materials synthesis. In particular, we are interested in seamlessly integrating inorganic structures together with biology for improved cell transfection and therapies, and designing new materials, often using diamondoid molecules as building blocks.
My group is very interested in how to design new inorganic structures that will seamless integrate with biological systems to address problems that are not feasible by other means. This involves both fundamental work such as to deeply understand how lipid membranes interact with inorganic surfaces, electrokinetic phenomena in biologically relevant solutions, and applying this knowledge into new device designs. Examples of this include “nanostraw” drug delivery platforms for direct delivery or extraction of material through the cell wall using a biomimetic gap-junction made using nanoscale semiconductor processing techniques. We also engineer materials and structures for neural interfaces and electronics pertinent to highly parallel data acquisition and recording. For instance, we have created inorganic electrodes that mimic the hydrophobic banding of natural transmembrane proteins, allowing them to ‘fuse’ into the cell wall, providing a tight electrical junction for solid-state patch clamping. In addition to significant efforts at engineering surfaces at the molecular level, we also work on ‘bridge’ projects that span between engineering and biological/clinical needs. My long history with nano- and microfabrication techniques and their interactions with biological constructs provide the skills necessary to fabricate and analyze new bio-electronic systems.
Research Interests:
Bio-inorganic Interface
Molecular materials at interfaces
Self-Assembly and Nucleation and Growth -
Teresa Meng
Reid Weaver Dennis Professor in Electrical Engineering and Professor of Computer Science, Emerita
BioTeresa H. Meng is the Reid Weaver Dennis Professor of Electrical Engineering, Emerita, at Stanford University. Her research activities in the first 10 years focused on low-power circuit and system design, video signal processing, and wireless communications. In 1998, Prof. Meng took leave from Stanford and founded Atheros Communications, Inc., which developed semiconductor system solutions for wireless network communications products. After returning to Stanford in 2000 to continue her teaching and research, Prof. Meng turned her research interest to applying signal processing and IC design to bio-medical engineering. She collaborated with Prof. Krishna Shenoy on neural signal processing and neural prosthetic systems. She also directed a research group exploring wireless power transfer and implantable bio-medical devices. Prof. Meng retired from Stanford in 2013.
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Vinod Menon
Rachael L. and Walter F. Nichols, MD, Professor and Professor, by courtesy, of Education and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsEXPERIMENTAL, CLINICAL AND THEORETICAL SYSTEMS NEUROSCIENCE
Cognitive neuroscience; Systems neuroscience; Cognitive development; Psychiatric neuroscience; Functional brain imaging; Dynamical basis of brain function; Nonlinear dynamics of neural systems. -
Mark Mercola
Professor of Medicine (Cardiovascular) and, by courtesy, of Chemical and Systems Biology
BioDr. Mercola is Professor of Medicine and Professor in the Stanford Cardiovascular Institute. He completed postdoctoral training at the Dana-Farber Cancer Institute and Harvard Medical School, was on the faculty in the Department of Cell Biology at Harvard Medical School for 12 years, and later at the Sanford-Burnham-Prebys Institute and Department of Bioengineering at the University of California, San Diego before relocating to Stanford in 2015.
Prof. Mercola is known for identifying many of the factors that are responsible for inducing and forming the heart, including the discovery that Wnt inhibition is a critical step in cardiogenesis that provided the conceptual basis and reagents for the large-scale production of cardiovascular tissues from pluripotent stem cells. He has collaborated with medicinal chemists, optical engineers and software developers to pioneer the use of patient iPSC-cardiomyocytes for disease modeling, safety pharmacology and drug development. His academic research is focused on developing and using quantitative high throughput assays of patient-specific cardiomyocyte function to discover druggable targets for preserving contractile function in heart failure and promoting regeneration following ischemic injury. He co-established drug screening and assay development at the Conrad Prebys Drug Discovery Center (San Diego), which operated as one of 4 large screening centers of the US National Institutes of Health (NIH) Molecular Libraries screening initiative and continues as one of the largest academic drug screening centers.
Prof. Mercola received an NIH MERIT award for his work on heart formation. He holds numerous patents, including describing the invention of the first engineered dominant negative protein and small molecules for stem cell and cancer applications. He serves on multiple editorial and advisory boards, including Vala Sciences, Regencor, The Ted Rogers Centre for Heart Research and the Human Biomolecular Research Institute. His laboratory is funded by the National Institutes of Health (NIH), California Institute for Regenerative Medicine, Phospholamban Foundation and Fondation Leducq. -
Everett Meyer
Associate Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy), of Pediatrics (Stem Cell Transplantation) and, by courtesy, of Surgery (Abdominal Transplantation)
Current Research and Scholarly InterestsResearch focus in T cell immunotherapy and T cell immune monitoring using high-throughput sequencing and genomic approaches, with an emphasis on hematopoietic stem cell transplantation, the treatment of graft-versus-host disease and immune tolerance induction.
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Timothy Meyer
Stanford University Professor of Nephrology, Emeritus
Current Research and Scholarly InterestsInadequate removal of uremic solutes contributes to widespread illness in the more than 500,000 Americans maintained on dialysis. But we know remarkably little about these solutes. Dr. Meyer's research efforts are focused on identifying which uremic solutes are toxic, how these solutes are made, and how their production could be decreased or their removal could be increased. We should be able to improve treatment if we knew more about what we are trying to remove.
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Sara Michie
Professor of Pathology (Research), Emerita
Current Research and Scholarly InterestsLymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules.
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Emmanuel Mignot, MD, PhD
Craig Reynolds Professor of Sleep Medicine and Professor, by courtesy, of Genetics and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsThe research focus of the laboratory is the study of sleep and sleep disorders such as narcolepsy and Kleine Levin syndrome. We also study the neurobiological and genetic basis of the EEG and develop new tools to study sleep using nocturnal polysomnography. Approaches mostly involve human genetic studies (GWAS, sequencing), EEG signal analysis (deep learning), and immunology (narcolepsy is an autoimmune disease of the brain). We also work on autoimmune encephalitis.
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Carlos Milla
Professor of Pediatrics (Pulmonary Medicine) and, by courtesy, of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly InterestsAt Stanford University I developed and currently direct the CF Translational Research Center. The overarching goal of the center is to provide the groundwork to streamline, accelerate, and promote the translation of basic discoveries into effective therapies and interventions to benefit patients affected by cystic fibrosis. My laboratory group currently has three main lines of investigation: respiratory cell biology in CF; remote biochemical monitoring; and lung physiology in young children.
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D. Craig Miller, M.D.
Thelma and Henry Doelger Professor of Cardiovascular Surgery, Emeritus
Current Research and Scholarly InterestsCardiac and heart valve disease with experimental laboratory large animal projects focused on the investigation of left ventricular and cardiac mechanics, bioenergetics, and LV and mitral valve physiology and pathophysiology. Current thrust is aimed at understanding the mitral valve and subvalvular mitral apparatus and transmural LV wall strains, thickening, and myolaminar fiber-sheet mechanics.
Clinical research interests include thoracic aortic diseases (aortic dissection, aneurysm) and cardiac valvular disease, including surgical treatment, endovascular thoracic aortic stent-graft repair, mitral valve repair, and valve-sparing aortic root replacement. -
William Mitch
Professor of Civil and Environmental Engineering
BioBill Mitch received a B.A. in Anthropology (Archaeology) from Harvard University in 1993. During his studies, he excavated at Mayan sites in Belize and surveyed sites dating from 2,000 B.C. in Louisiana. He switched fields by receiving a M.S. degree in Civil and Environmental Engineering at UC Berkeley. He worked for 3 years in environmental consulting, receiving his P.E. license in Civil Engineering in California. Returning to UC Berkeley in 2000, he received his PhD in Civil and Environmental Engineering in 2003. He moved to Yale as an assistant professor after graduation. His dissertation received the AEESP Outstanding Doctoral Dissertation Award in 2004. At Yale, he serves as the faculty advisor for the Yale Student Chapter of Engineers without Borders. In 2007, he won a NSF CAREER Award. He moved to Stanford University as an associate professor in 2013.
Employing a fundamental understanding of organic chemical reaction pathways, his research explores links between public health, engineering and sustainability. Topics of current interest include:
Public Health and Emerging Carcinogens: Recent changes to the disinfection processes fundamental to drinking and recreational water safety are creating a host of highly toxic byproducts linked to bladder cancer. We seek to understand how these compounds form so we can adjust the disinfection process to prevent their formation.
Global Warming and Oceanography: Oceanic dissolved organic matter is an important global carbon component, and has important impacts on the net flux of CO2 between the ocean and atmosphere. We seek to understand some of the important abiotic chemical reaction pathways responsible for carbon turnover.
Sustainability and Persistent Organic Pollutants (POPs): While PCBs have been banned in the US, we continue to produce a host of structurally similar chemicals. We seem to understand important chemical pathways responsible for POP destruction in the environment, so we can design less persistent and problematic chemicals in the future.
Engineering for Sustainable Wastewater Recycling: The shortage of clean water represents a critical challenge for the next century, and has necessitated the recycling of wastewater. We seek to understand ways of engineer this process in ways to minimize harmful byproduct formation.
Carbon Sequestration: We are evaluating the formation of nitrosamine and nitraminecarcinogens from amine-based carbon capture, as well as techniques to destroy any of these byproducts that form. -
Anish Mitra
Assistant Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology)
BioAnish Mitra is a neuroscientist and psychiatrist interested in understanding how neural activity in large-scale networks causes mental illness.
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Daria Mochly-Rosen
George D. Smith Professor of Translational Medicine
Current Research and Scholarly InterestsTwo areas: 1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling. Focus: protein kinase C in heart and large GTPases regulating mitochondrial dynamics in neurodegdenration. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, and glucose-6-phoshate dehydrogenase, in normal cells and in models of human diseases.
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W. E. Moerner
Harry S. Mosher Professor and Professor, by courtesy, of Applied Physics
Current Research and Scholarly InterestsLaser spectroscopy and microscopy of single molecules to probe biological systems, one biomolecule at a time. Primary thrusts: fluorescence microscopy far beyond the optical diffraction limit (PALM/STORM/STED), methods for 3D optical microscopy in cells, and trapping of single biomolecules in solution for extended study. We explore protein localization patterns in bacteria, structures of amyloid aggregates in cells, signaling proteins in the primary cilium, and dynamics of DNA and RNA.
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Matteo Amitaba Mole'
Assistant Professor of Obstetrics and Gynecology (Reproductive, Perinatal & Stem Cell Biology Research)
Current Research and Scholarly InterestsWe study how the human embryo implants inside the maternal uterine tissue to establish a healthy pregnancy and the underlying maternal-embryo communication.
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Denise M. Monack
Martha Meier Weiland Professor in the School of Medicine
Current Research and Scholarly InterestsThe primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis. We use several model systems to study complex host-pathogen interactions in the gut and in immune cells such as macrophages and dendritic cells. Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response.
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Stephen Monismith
Obayashi Professor in the School of Engineering and Professor of Oceans
Current Research and Scholarly InterestsHydrodynamics of lakes, estuaries, coral reefs, kelp forests and the coastal ocean
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Michelle Monje
Milan Gambhir Professor of Pediatric Neuro-Oncology and Professor, by courtesy, of Neurosurgery, of Pediatrics, of Pathology and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsThe Monje Lab studies the molecular and cellular mechanisms of postnatal neurodevelopment. This includes microenvironmental influences on neural precursor cell fate choice in normal neurodevelopment and in disease states.
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Andrea Montanari
John D. and Sigrid Banks Professor and Professor of Mathematics
BioI am interested in developing efficient algorithms to make sense of large amounts of noisy data, extract information from observations, estimate signals from measurements. This effort spans several disciplines including statistics, computer science, information theory, machine learning.
I am also working on applications of these techniques to healthcare data analytics. -
Stephen B. Montgomery
Stanford Medicine Professor of Pathology, Professor of Genetics and of Biomedical Data Science
Current Research and Scholarly InterestsWe focus on understanding the effects of genome variation on cellular phenotypes and cellular modeling of disease through genomic approaches such as next generation RNA sequencing in combination with developing and utilizing state-of-the-art bioinformatics and statistical genetics approaches. See our website at http://montgomerylab.stanford.edu/
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Thomas Montine, MD, PhD
Stanford Medicine Professor of Pathology
BioDr. Montine received his education at Columbia University (BA in Chemistry), the University of Rochester (PhD in Pharmacology), and McGill University (MD and CM). His postgraduate medical training was at Duke University, and he was junior faculty at Vanderbilt University where he was awarded the Thorne Professorship in Pathology. In 2002, Dr. Montine was appointed as the Alvord Endowed Professor in Neuropathology and Director of the Division of Neuropathology at the University of Washington. He was Director of the University of Washington Alzheimer’s Disease Research Center, one of the original 10 Centers in the US, and passed that responsibility to able colleagues. Dr. Montine was the founding Director of the Pacific Udall Center, a NINDS-funded Morris K. Udall Centers of Excellence for Parkinson’s Disease Research. In 2010, Dr. Montine was appointed Chair of the Department of Pathology at the University of Washington. In 2016, Dr. Montine was appointed Chair of the Department of Pathology at Stanford University where he is the Stanford Medicine Endowed Professor in Pathology.
The focus of the Montine Laboratory is on the structural and molecular bases of cognitive impairment. The Montine Laboratory addresses this prevalent, unmet medical need through a combination of neuropathology, biomarkers for detection and progression of early disease, and experimental studies that test hypotheses concerning specific mechanisms of neuron injury and then develop novel approaches to neuroprotection. Our current approaches include small molecule precision therapeutics and cell replacement strategies for brain. -
Tirin Moore
Ben Barres Professor
Current Research and Scholarly InterestsWe study neural circuit mechanisms of visual perception, cognition and sensorimotor integration.
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Erin Mordecai
Associate Professor of Biology and Senior Fellow at the Woods Institute for the Environment
Current Research and Scholarly InterestsOur research focuses on the ecology of infectious disease. We are interested in how climate, species interactions, and global change drive infectious disease dynamics in humans and natural ecosystems. This research combines mathematical modeling and empirical work. Our main study systems include vector-borne diseases in humans and fungal pathogens in California grasses.
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Elizabeth Mormino
Associate Professor (Research) of Neurology and Neurological Sciences (Neurology Research)
BioDr. Beth Mormino completed a PhD in Neuroscience at UC Berkeley in the laboratory of Dr. William Jagust, where she performed some of the initial studies applying Amyloid PET with the tracer PIB to clinically normal older individuals. This initial work provided evidence that the pathophysiological processes of Alzheimer’s disease begin years before clinical symptoms and are associated with subtle changes to brain regions critical for memory. During her postdoctoral fellowship with Drs. Reisa Sperling and Keith Johnson at Massachusetts General Hospital she used multimodal imaging techniques to understand longitudinal cognitive changes among individuals classified as preclinical AD. In 2017, Dr. Mormino joined the faculty at Stanford University in the department of Neurology and Neurological Sciences. Her research program focuses on combining imaging and genetics to predict cognitive trajectories over time, and the integration of novel PET scans to better understand human aging and neurodegenerative diseases.
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Ashby Morrison
Associate Professor of Biology
Current Research and Scholarly InterestsOur research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity.
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Michael Moseley
Professor of Radiology (Radiological Sciences Lab)
Current Research and Scholarly InterestsMR physics into tissue contrast mechanisms such as diffusion, perfusion, and functional imaging describes the research direction. Applications of cerebral stroke (brain attacks) and neurocognitive disorders are also being developed from these methods
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Darius M. Moshfeghi, MD
Professor of Ophthalmology
Current Research and Scholarly InterestsDr. Moshfeghi leads the Stanford University Network for Diagnosis of Retinopathy of Prematurity (SUNDROP network) and the Pediatrix-Stanford collaboration TeleROP. Between these 2 screening programs, nearly 2% of United States neonatal intensive care units are being provided telemedicine screening services through Stanford University.
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Heather E. Moss, MD, PhD
Professor of Ophthalmology and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsI am a clinician scientist with a background in engineering, epidemiology and neuro-ophthalmology. In my research, I combine tools from these disciplines with the goal of understanding and preventing vision loss from optic nerve diseases. My focus is on papilledema, the swelling of the optic nerve head due to elevation in intracranial pressure, which we are characterizing using electrophysiological and imaging techniques. Other areas of interest are peri-operative vision loss and optic neuritis.
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Philippe Mourrain
Associate Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator)
BioExpertise: Neurobiology, Sleep sciences, Molecular Genetics, Developmental Biology, Gene Silencing/Epigenetics
Methodology: Synapse Imaging (Two photon microscopy, Array Tomography), Calcium Imaging (Light Sheet Microscopy/SPIM, Light Field Microscopy), Optogenetics, CLARITY, Tol2 transgenesis, TALENs, CRISPR/Cas9, Video tracking and behavior computation. -
Prithvi Mruthyunjaya, MD, MHS
Alan Adler Professor of Ophthalmology and Professor, by courtesy, of Radiation Oncology
Current Research and Scholarly InterestsDr Mruthyunjaya has maintained a broad research interest with publications in both ocular oncology and retinal diseases.
His focus is on multi-modal imaging of ocular tumors and understanding imaging clues that may predict vision loss after ocular radiation therapy. He coordinates multi-center research on the role of genetic testing and outcomes of treatments of ocular melanoma.
In the field of retinal diseases, his interests are in intra-operative imaging to enhance surgical accuracy. -
Mary Beth Mudgett
Senior Associate Dean for the Natural Sciences and Susan B. Ford Professor
Current Research and Scholarly InterestsMy laboratory investigates how bacterial pathogens employ proteins secreted by the type III secretion system (TTSS) to manipulate eukaryotic signaling to promote disease. We study TTSS effectors in the plant pathogen Xanthomonas euvesicatoria, the causal agent of bacterial spot disease of pepper and tomato. For these studies, we apply biochemical, cell biological, and genetic approaches using the natural hosts and model pathosystems.
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Kunal Mukherjee
Assistant Professor of Materials Science and Engineering
BioKunal Mukherjee is an assistant professor in Materials Science and Engineering at Stanford. He has been an assistant professor in the Materials department at UC Santa Barbara (2016-2020), held postdoctoral appointments at IBM TJ Watson Research Center (2016) and MIT (2015), and worked as a transceiver engineer at Finisar (2009-2010).
The Mukherjee group specializes in semiconductors that emit and detect light in the infrared. Our research enables better materials for data transmission, sensing, manufacturing, and environmental monitoring. We make high-quality thin films with IV-VI (PbSnSe) and III-V (GaAs-InAs/GaSb) material systems and spend much of our time understanding how imperfections in the crystalline structure such as dislocations and point defects impact their electronic and optical properties. This holds the key to directly integrating these semiconductors with silicon and germanium substrates for new hybrid circuits that combine infrared photonics and conventional electronics. -
Ann Mullally
Professor of Medicine (Hematology)
Current Research and Scholarly InterestsDr. Ann Mullally's aboratory studies the genetics, biology and therapy of myeloid blood cancers, with a focus on myeloproliferative neoplasms (MPN). Using primary human samples, mouse models, genomics, single-cell sequencing and CRISPR, as well as cellular and molecular biology, the lab has investigated the key genetic events underlying MPN pathogenesis. Dr. Mullally’s lab elucidated the mechanism by which mutant calreticulin (CALR) is oncogenic and causes MPN.
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Mark Musen
Stanford Medicine Professor of Biomedical Informatics Research, Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Current Research and Scholarly InterestsModern science requires that experimental data—and descriptions of the methods used to generate and analyze the data—are available online. Our laboratory studies methods for creating comprehensive, machine-actionable descriptions both of data and of experiments that can be processed by other scientists and by computers. We are also working to "clean up" legacy data and metadata to improve adherence to standards and to facilitate open science broadly.
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David Myung, MD, PhD
Associate Professor of Ophthalmology and, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsNovel biomaterials to reconstruct the wounded cornea
Mesenchymal stem cell therapy for corneal and ocular surface regeneration
Engineered biomolecule therapies for promote corneal wound healing
Telemedicine in ophthalmology -
Claude M. Nagamine, DVM, PhD
Associate Professor of Comparative Medicine
Current Research and Scholarly InterestsMouse models to study murine and human infectious diseases. These colloborative studies include dengue virus, zika virus, adeno-associated virus, coxsackie virus, enterovirus 71, enterohepatic helicobacters, campylobacters, and anaplasma.
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Hiromitsu (Hiro) Nakauchi
Professor of Genetics (Stem Cell)
Current Research and Scholarly InterestsTranslation of discoveries in basic research into practical medical applications
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Sandy Napel
Professor of Radiology (Integrative Biomedical Imaging Informatics), Emeritus
Current Research and Scholarly InterestsMy research seeks to advance the clinical and basic sciences in radiology, while improving our understanding of biology and the manifestations of disease, by pioneering methods in the information sciences that integrate imaging, clinical and molecular data. A current focus is on content-based radiological image retrieval and integration of imaging features with clinical and molecular data for diagnostic, prognostic, and therapy planning decision support.
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Sanjiv Narayan
Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsDr. Narayan directs the Computational Arrhythmia Research Laboratory, whose goal is to define the mechanisms underlying complex human heart rhythm disorders, to develop bioengineering-focused solutions to improve therapy that will be tested in clinical trials. The laboratory has been funded continuously since 2001 by the National Institutes of Health, AHA and ACC, and interlinks a disease-focused group of clinicians, computational physicists, bioengineers and trialists.
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Jayakar V. Nayak, MD, PhD
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsUpper Airway Stem Cell Biology, Fate, and Repair/Regeneration of the Airway Epithelium to treat Upper and Lower Airway Disorders
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Joel Neal, MD, PhD
Professor of Medicine (Oncology)
Current Research and Scholarly InterestsI am a thoracic oncologist who cares for patients with non-small cell lung cancer, malignant mesothelioma, and other thoracic malignancies. I design and conduct clinical trials of novel therapies in collaboration with other researchers and pharmaceutical companies. These generally focus on two areas, 1) targeted therapies against particular mutations in cancers (for example EGFR, ALK, ROS1, HER2, KRAS, MET, and others) and 2) the emerging field of immunotherapy in cancer, using anti PD-1/PD-L1 therapies in combination with other agents, and also developing cellular therapies. I also collaborate with other researchers on campus to apply emerging technologies to cancer therapy, for example, circulating tumor DNA detection. Additionally, in my role as the Cancer Center IT Medical Director, I coordinate projects relating to our use of the electronic health record to improve provider efficiency and facilitate patient care.
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Robert Negrin
Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy)
Current Research and Scholarly InterestsOur labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells.
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Drew Nelson
Professor of Mechanical Engineering, Emeritus
BioResearch involves development of improved methods for predicting the fatigue life of engineering materials, incuding the effects of manufacturing processes, and investigation of new approaches in the field of experimental mechanics, such as determination of residual stresses using optical methods.
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Lorene Nelson, PhD
Associate Professor of Epidemiology and Population Health
Current Research and Scholarly InterestsPrimary research interests:
- genetic, environmental and lifestyle determinants of neurodegenerative disorders
(amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, migraine)
- innovative study design and data ecosystems in clinical and public health
Primary educational interests:
- Training of next generation scientists in advanced data science and analytic methods
in population, social, and behavioral health sciences.
