Wu Tsai Human Performance Alliance
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Professor of Psychology
Current Research and Scholarly InterestsMy lab and I seek to elucidate the neural basis of emotion (affective neuroscience), and explore implications for decision-making (neuroeconomics) and psychopathology (neurophenomics).
Associate Professor of Aeronautics and Astronautics and, by courtesy, of Computer Science
BioMykel Kochenderfer is Associate Professor of Aeronautics and Astronautics at Stanford University. Prior to joining the faculty, he was at MIT Lincoln Laboratory where he worked on airspace modeling and aircraft collision avoidance, with his early work leading to the establishment of the ACAS X program. He received a Ph.D. from the University of Edinburgh and B.S. and M.S. degrees in computer science from Stanford University. Prof. Kochenderfer is the director of the Stanford Intelligent Systems Laboratory (SISL), conducting research on advanced algorithms and analytical methods for the design of robust decision making systems. Of particular interest are systems for air traffic control, unmanned aircraft, and other aerospace applications where decisions must be made in uncertain, dynamic environments while maintaining safety and efficiency. Research at SISL focuses on efficient computational methods for deriving optimal decision strategies from high-dimensional, probabilistic problem representations. He is an author of "Decision Making under Uncertainty: Theory and Application" (2015), "Algorithms for Optimization" (2019), and "Algorithms for Decision Making" (2022), all from MIT Press. He is a third generation pilot.
Assistant Professor (Research) of Radiology (Musculoskeletal Imaging)
Current Research and Scholarly InterestsMy research is focused on the development and clinical translation of novel imaging techniques geared toward early detection of musculoskeletal disease. Current projects include whole-joint molecular imaging of early disease with PET-MRI, imaging of early cartilage changes in Osteoarthritis (OA) with GagCEST, rapid knee imaging and simultaneous bilateral knee MRI.
BioJulie Kolesar is a Research Engineer in the Human Performance Lab, supporting teaching and interdisciplinary research at the crossroads of engineering, sports medicine, and athletics. Her work aims to understand the underlying mechanisms relating biomechanical changes with function and quality of life for individuals with musculoskeletal disorders and injuries. As part of the Wu Tsai Human Performance Alliance, Dr. Kolesar engages in collaborations which seek to optimize human health and performance across the lifespan. Her expertise and research interests include experimental gait analysis, musculoskeletal modeling and simulation, and clinical interventions and rehabilitation.
Clinical Assistant Professor, Orthopaedic Surgery
BioDr. Kraus is a Clinical Assistant Professor at Stanford Children’s Orthopedic and Sports Medicine Center trained in the specialty of Physical Medicine and Rehabilitation (PM&R) sports medicine. She has research and clinical interests in endurance sports medicine, injury prevention, running biomechanics, prevention of bone stress injuries, and the promotion of health and wellness at any age of life. Dr. Kraus is the director of the FASTR Program, which stands for Female Athlete Science and Translational Research. The FASTR program is supported by the Wu Tsai Human Performance Alliance and seeks to close the gender gap in sports science research with an emphasis on early identification and interventions to prevent injury and identify ways to optimize performance in female athletes. Dr. Kraus is also a member of the U.S. Olympic and Paralympic Committee Women's Health Task Force and is the medical director of the Stanford Children's Motion Analysis and Sport Performance Lab. She has completed nine marathons including the Boston Marathon twice and one 50k ultramarathon. With running and staying physically active as one of her personal passions, she recognizes the importance of fitness for overall wellbeing and the prevention of chronic medical conditions.
Research Technical Manager, Wu Tsai Human Performance Alliance
Current Role at StanfordJoy Ku is focused on biocomputation and the advancement of their use through teaching, science communications, community building, and the promotion of research resource sharing efforts, particularly as related to reproducibility and open-source science.
She is currently Deputy Director of the Wu Tsai Human Performance Alliance at Stanford (https://humanperformance.stanford.edu) and also leads the education and outreach efforts for the overall Wu Tsai Human Performance Alliance, which consists of institutions across the country, including Boston Children's Hospital, Salk, UC San Diego, the University of Kansas, and the University of Oregon. The Alliance's mission is to discover biological principles to optimize human performance and catalyze innovations in human health.
Dr. Ku is also the Director of Promotions and Didactic Interactions for the NIH-funded Restore Center (https://restore.stanford.edu), as well as the Director of Education and Communications for the Mobilize Center (https://mobilize.stanford.edu), an NIH Biomedical Technology Resource Center. Both Centers provide tools, infrastructure, and training to support the research community. The Mobilize Center's emphasis is on biomechanical modeling and machine learning algorithms to provide new insights into human movement from data sources, such as wearables, video, and medical images. The Restore Center's mission is to advance rehabilitation research using mobile sensor and video technology for real-world assessments of movement and factors affecting movement.
She also manages SimTK (https://simtk.org), a software, model, and data-sharing platform for the biocomputation research community.
Walter B Reinhold Professor in the School of Engineering, Robert Bosch Chair of Mechanical Engineering, Professor of Mechanical Engineering and, by courtesy, of Bioengineering
Current Research and Scholarly Interestscomputaitonal simulation of brain development, cortical folding, computational simulation of cardiac disease, heart failure, left ventricular remodeling, electrophysiology, excitation-contraction coupling, computer-guided surgical planning, patient-specific simulation
Associate Professor of Genetics
Current Research and Scholarly InterestsWe develop statistical and machine learning frameworks to learn predictive, dynamic and causal models of gene regulation from heterogeneous functional genomics data.
Andrea Lynn Kussman
Member, Wu Tsai Human Performance Alliance
Current Research and Scholarly InterestsDr. Kussman conducts research on injury prevention and athlete wellness. Specific areas of interest include the female athlete, endurance athletes, bone health, mental health in athletes, exercise as medicine, and medical education. Previous research has included work on the female and male athlete triad, eating disorders in athletes, mental health in athletes, mononucleosis infection in athletes, cardiac complications of COVID-19, and concussion.
Amy Ladd, MD
Elsbach-Richards Professor of Surgery and Professor, by courtesy, of Medicine (Immunology & Rheumatology) and of Surgery (Plastic and Reconstructive Surgery)
Current Research and Scholarly InterestsResearch Interests
1. The kinematics and forces associated with thumb carpometcarpal (CMC) function and pathology
2. The anatomy, microstructure, and immunofluorescent characteristics of the thumb CMC joint
3. Pathomechaniics of CMC arthritis: biomechanical wear, injury, genetic, and environmental causes
4. Archiving, vitalizing, and innovating medical and surgical knowledge, most recently with innovative iBook monographs
Anand Rajaraman and Venky Harinarayan Professor
Current Research and Scholarly InterestsLanday's current research interests include Technology to Support Behavior Change (especially for health and sustainability), Demonstrational User Interfaces, Mobile & Ubiquitous Computing, Cross-Cultural Interface Design, Human-Centered AI, and User Interface Design Tools. He has developed tools, techniques, and a top professional book on Web Interface Design.
Maarten Lansberg, MD, PhD
Professor of Neurology and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy research involves the design and conduct of clinical trials to discover new treatments for patients who have suffered a stroke. These trials span treatment of acute stroke, stroke recovery, and stroke prevention. My research in acute stroke is primarily focused on the use of advanced neuroimaging methods (CT and MRI) to select patients who are most likely to benefit from therapies aimed at restoring blood flow to the brain in patients who have suffered a stroke.
Associate Professor of Mechanical Engineering and, by courtesy, of Radiology (Radiological Sciences Laboratory)On Leave from 04/01/2023 To 06/30/2023
Current Research and Scholarly InterestsMy lab's research involves the function, degeneration and repair of musculoskeletal soft tissues, with a focus on meniscal fibrocartilage and articular cartilage. We are particularly interested in the complex interactions between biophysical and biochemical cues in controlling cell behavior, the roles of these interactions in degenerative conditions such as osteoarthritis, and development of tissue engineered 3D model systems for studying physical influences on primary and progenitor cells.
Y. Joyce Liao, MD, PhD
Professor of Ophthalmology and of Neurology
Current Research and Scholarly InterestsIschemic optic neuropathy
Stem cell transplantation
Eye movement disorders
Michael Lim, M.D.
Professor of Neurosurgery and, by courtesy, of Radiation Oncology (Radiation Therapy), of Medicine (Oncology), of Otolaryngology - Head & Neck Surgery (OHNS) and of Neurology
BioDr. Lim is the Chair of the Department of Neurosurgery and a board-certified neurosurgeon specializing in brain tumors and trigeminal neuralgia.
Dr. Lim’s clinical interests include the treatment of benign and malignant brain tumors, with special interest in gliomas, meningiomas, metastatic tumors, and skull base tumors. Dr. Lim also specializes in surgical treatments for trigeminal neuralgia. During his time at Johns Hopkins, Dr. Lim built one of the largest brain tumor and trigeminal neuralgia practices and utilized the most advanced surgical technologies and techniques for his patients. As a passionate voice for patient experience, he has been recognized by his peers and patients for his integrity and compassionate care, including a Service Excellence Award from HealthNetwork Foundation.
As a mentor, he has garnered numerous teaching awards, including being honored as an outstanding teacher by Johns Hopkins University School of Medicine. He is actively involved in shaping education for neurosurgery and oncology across the United States and around the world.
Dr. Lim’s research interests focus on harnessing the immune system to fight cancer. His laboratory focuses on understanding mechanisms of immune evasion by cancer cells. He has successfully translated his findings from the laboratory to the clinics and has conducted and led several large national immunotherapy clinical trials for brain tumors.
Dr. Lim’s bibliography contains well over 200 articles on topics such as immunotherapy for glioblastoma, long-term survival of glioma patients treated with stereotactic radiation, and treatment of neuropathic pain. His work has appeared in Science Translational Medicine, Clinical Cancer Research, Lancet Oncology, Nature Immunology, and many more publications. He also has written 20 book chapters and monographs.
Dr. Lim is a world leader in immunotherapy for brain tumors. In addition to being invited world-wide to give lectures and seminars, he has given platform presentations on the topics of immunotherapy for brain tumors, neurosurgical techniques and management of brain tumors at the American Society of Clinical Oncologists, American Academy of Neurological Surgeons, Radiological Society of North America, Annual Symposium on Brain and Spine Metastases, Congress of Neurological Surgeons, and other meetings. In addition, he has served as platform chairman of the CNS session at the American Society for Clinical Oncology conference.
Dr. Lim is a member of the American Society for Clinical Oncology, Congress of Neurological Surgeons, American Association of Neurological Surgeons, and Society for Neuro-Oncology. Dr. Lim served as the program co-chair of the Society for Neuro-Oncology and CNS section of the American Society for Clinical Oncology. He also served on many executive committees, including the Executive Committee for the Joint Tumor Section of the American Association of Neurological Surgeons and Congress of Neurological Surgeons.
Scott W Linderman
Assistant Professor of Statistics and, by courtesy, of Computer Science and of Electrical Engineering
BioScott is an Assistant Professor of Statistics and, by courtesy, Electrical Engineering and Computer Science at Stanford University. He is also an Institute Scholar in the Wu Tsai Neurosciences Institute and a member of Stanford Bio-X and the Stanford AI Lab. His lab works at the intersection of machine learning and computational neuroscience, developing statistical methods to analyze large scale neural data. Previously, Scott was a postdoctoral fellow with Liam Paninski and David Blei at Columbia University, and he completed his PhD in Computer Science at Harvard University with Ryan Adams and Leslie Valiant. He obtained his undergraduate degree in Electrical and Computer Engineering from Cornell University and spent three years as a software engineer at Microsoft before graduate school.
Instructor, Medicine - Cardiovascular Medicine
Current Research and Scholarly InterestsInterested in the genetics of human performance and the multi-omic response to exercise and training for optimizing human health.
C. Karen Liu
Associate Professor of Computer Science
BioC. Karen Liu is an associate professor in the Computer Science Department at Stanford University. Prior to joining Stanford, Liu was a faculty member at the School of Interactive Computing at Georgia Tech. She received her Ph.D. degree in Computer Science from the University of Washington. Liu's research interests are in computer graphics and robotics, including physics-based animation, character animation, optimal control, reinforcement learning, and computational biomechanics. She developed computational approaches to modeling realistic and natural human movements, learning complex control policies for humanoids and assistive robots, and advancing fundamental numerical simulation and optimal control algorithms. The algorithms and software developed in her lab have fostered interdisciplinary collaboration with researchers in robotics, computer graphics, mechanical engineering, biomechanics, neuroscience, and biology. Liu received a National Science Foundation CAREER Award, an Alfred P. Sloan Fellowship, and was named Young Innovators Under 35 by Technology Review. In 2012, Liu received the ACM SIGGRAPH Significant New Researcher Award for her contribution in the field of computer graphics.
Stanley Yung Liu, MD, DDS, FACS
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Surgery (Plastic and Reconstructive Surgery)
BioDr. Liu is as an Associate Professor of Otolaryngology, and by courtesy, of Plastic and Reconstructive Surgery at Stanford University School of Medicine. He is director of the Stanford Sleep Surgery Fellowship, and preceptor to the Stanford Oculoplastic Surgery Fellowship. He is a Stanford Biodesign Faculty Fellow Alumnus.
After graduating from Stanford University with a degree in Biology, Dr. Liu received medical and dental degrees from the University of California-San Francisco (UCSF). He was a former Howard Hughes Medical Institute (HHMI) Research Scholar and spent a year at the NIH. After oral and maxillofacial surgery residency at UCSF, he completed the Stanford sleep surgery fellowship in 2014 with the Department of Otolaryngology and sleep surgery pioneer Dr. Robert Riley.
Dr. Liu practices the full scope of sleep apnea surgery including nasal, palate, tongue base, hypoglossal nerve stimulation, genioglossus advancement, and maxillomandibular advancement (MMA). He introduced adult maxillary expansion (DOME) for OSA with Professor Christian Guilleminault in 2015, and has continued to update the comprehensive sleep surgery protocol at Stanford.
He is also routinely referred patients who need complex facial trauma reconstruction and orthognathic surgery.
Dr. Liu's active areas of research include clinical phenotyping to optimize sleep surgery outcome, virtual surgical planning for facial skeletal surgery, and neuromodulation of the upper airway. He has given keynote talks nationally and internationally at preeminent conferences across specialties. He has published over 90 scientific articles and medical texts, with original scientific work on sleep surgery.
Eric Rothenberg, MD Professor and Professor, by courtesy, of Pediatrics
Current Research and Scholarly InterestsJames Lock, MD, Ph.D. is Professor of Child Psychiatry and Pediatrics in the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine where he has taught since 1993. He is board certified in adult as well as child and adolescent psychiatry. He directs the eating disorder program in Child Psychiatry and is active in treatment research for children and adolescents with eating disorders.
Jonathan Z. Long
Assistant Professor of Pathology
BioDr. Jonathan Long is an Assistant Professor of Pathology and an Institute Scholar of Stanford ChEM-H (Chemistry, Engineering & Medicine for Human Health). Prior to arriving to Stanford in 2018, Dr. Long completed his Ph.D. in Chemistry at Scripps Research with Benjamin F. Cravatt and his postdoctoral work at Harvard Medical School/Dana-Farber Cancer Institute with Bruce M. Spiegelman. His contributions in the areas of lipid biochemistry and energy homeostasis have been recognized by numerous awards from the National Institutes of Health and the American Diabetes Association. At Stanford, the Long laboratory studies signaling pathways in mammalian energy metabolism. The long-term goal of this work is to discover new molecules and pathways that can be translated into therapeutic opportunities for obesity, metabolic disease, and other age-associated chronic diseases.
Dr. Michael T. Longaker
Deane P. and Louise Mitchell Professor in the School of Medicine and Professor, by courtesy, of Materials Science and Engineering
Current Research and Scholarly InterestsWe have six main areas of current interest: 1) Cranial Suture Developmental Biology, 2) Distraction Osteogenesis, 3) Fibroblast heterogeneity and fibrosis repair, 4) Scarless Fetal Wound Healing, 5) Skeletal Stem Cells, 6) Novel Gene and Stem Cell Therapeutic Approaches.
Tanya Marie Luhrmann
Albert Ray Lang Professor
Current Research and Scholarly InterestsHer work focuses on the edge of experience: on voices, visions, the world of the supernatural and the world of psychosis. She has done ethnography on the streets of Chicago with homeless and psychotic women, and worked with people who hear voices in Chennai, Accra and the South Bay. She has also done fieldwork with evangelical Christians who seek to hear God speak back, with Zoroastrians who set out to create a more mystical faith, and with people who practice magic.
Angela K. Lumba-Brown
Clinical Associate Professor, Emergency Medicine
Clinical Associate Professor (By courtesy), Neurosurgery
Clinical Associate Professor, Pediatrics
Current Research and Scholarly InterestsCurrent research includes evidence-based guidelines for the management and treatment of traumatic brain injury, research establishing an evidence and targeting treatments for the subtypes of concussion, research identifying the best outcomes in pre-hospital care of patients with traumatic brain injury, research on brain performance via sensorimotor and sensory-cognitive synchronization, and research on dynamic visual synchronization as a biomarker for attentional impairments.
Postdoctoral Scholar, Mechanical Engineering
BioMy research interests include a broad variety of topics, ranging from medical image analysis and signal processing, machine learning and artificial intelligence, which I mainly focused on during my Ph.D. research. As a member of the Digital Athlete project of the Wu Tsai Performance Allience, I am now pursuing research to investigate how we can use wearable sensors, machine learning and biomechanical simulations to improve athlete performance, prevent injuries and support rehabilitation after injury.
I completed my Bachelor of Science and Master of Science degrees in medical engineering from Friedrich-Alexander-University Erlangen-Nuernberg (FAU). In 2015, I worked on my master’s thesis under the supervision of Prof. Kamiar Aminian during a research stay in the Laboratory of Movement Analysis and Measurement (LMAM), École Polytechnique Fédérale de Lausanne (EPFL), supported by a DAAD Scholarship. Afterwards, I pursued my Ph.D. at FAU in the Pattern Recognition Laboratory under the supervision of Prof. Andreas Maier and in the Machine Learning and Data Analytics Lab under the supervision of Prof. Bjoern Eskofier. I worked on projects in collaboration with Stanford University and the Universidade do Vale do Rio dos Sinos (UNISINOS) and conducted several short-term research stays at the partner universities. After finishing my Ph.D. in 2021, I joined Stanford University as a postdoctoral scholar advised by Prof. Ellen Kuhl.
Boston Scientific Applied Biomedical Engineering Professor and Professor of Bioengineering
Current Research and Scholarly InterestsDr. Josh Makower is the Boston Scientific Applied Bioengineering Professor of Medicine and of Bioengineering at the Stanford University Schools of Medicine and Engineering and the Director of the Stanford Byers Center for Biodesign, the program he co-founded with Dr. Paul Yock twenty years ago. Josh helped create the fundamental structure of the Center’s core curriculum and is the chief architect of what is now called “The Biodesign Process.” Over the past 20 years since Josh and Paul founded Biodesign, this curriculum and the associated textbook has been used at Stanford and across the world to train hundreds of thousands of students, faculty and industry leaders on the Biodesign process towards the advancement of medical innovation for the improvement of patient care. Josh has practiced these same techniques directly as the Founder & Executive Chairman of ExploraMed, a medical device incubator, creating 9 companies since 1995. Transactions from the ExploraMed portfolio include NeoTract, acquired by Teleflex, Acclarent, acquired by J&J, EndoMatrix, acquired by C.R. Bard & TransVascular, acquired by Medtronic. Other ExploraMed/NEA ventures include Moximed, NC8 and Willow. Josh is also a Special Partner at NEA where he supports the healthcare team and medtech/healthtech investing practice. Josh serves on the boards of Allay Therapeutics, Revelle Aesthetics, Setpoint Medical, DOTS Technologies, Eargo, ExploraMed, Intrinsic Therapeutics, Moximed, Willow and Coravin. Josh holds over 300 patents and patent applications. He received an MBA from Columbia University, an MD from the NYU School of Medicine, a bachelor’s degree in Mechanical Engineering from MIT. Josh is a Member of the National Academy of Engineering and the College of Fellows of The American Institute for Medical and Biological Engineering and was awarded the Coulter Award for Healthcare Innovation by the Biomedical Engineering Society in 2018.
Maryam S. Makowski, PhD, FACN, NBC-HWC
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioMaryam Sarah Makowski, Ph.D., FACN, NBC-HWC is a clinical assistant professor in the Stanford University Department of Psychiatry and Behavioral Sciences, the Associate Director of Scholarship and Health Promotion of the Stanford Medicine WellMD & WellPhD, and a nutrition and physician well-being coach at Stanford University. Dr. Makowski is a member of the WellConnect Program, Lifestyle Psychiatry Clinic, Metabolic Psychiatry Clinic, and Measurement-Based Care (CHOIR) team in the Department of Psychiatry and Behavioral Sciences. She is a member of the Well-being Advisory Committee and a Stanford School of Medicine alternate faculty senate of the Department of Psychiatry and Behavioral Sciences. Dr. Makowski has particular expertise in nutrition and physician well-being. She has been leading many initiatives to promote physician well-being at Stanford via personal and organizational strategies for over 6 years.
Dr. Makowski completed her master's and doctoral studies in clinical nutrition, nutritional epidemiology, and medical science at the University of Toronto in Canada. Prior to joining Stanford, she served as a scientific associate at Toronto General Hospital-University Health Network in Toronto, and as an advisor to Air Canada rouge pilots and cabin crew on optimal nutrition for fatigue mitigation. Over the course of her career, she has authored many highly cited scientific papers on nutrition and well-being.
She is a National Board-Certified Health and Wellness Coach, a Fellow of the American College of Nutrition, a professional member of the Academy of Nutrition and Dietetics, American and Canadian Nutrition Societies, American Nutrition Association, and The Institute of Coaching at McLean (a Harvard Medical School Affiliate).
William J. Maloney, MD
Boswell Chair of Orthopaedics
Current Research and Scholarly InterestsDr. Maloney is nationally and internationally recognized for his contributions to the improved understanding of the causes of failure of surgical joint replacement. For example; he established a critical link between polyethylene wear debris and bony erosion, with resulting significant changes in the materials and design strategies of joint replacement surgery. More recently, he has shown that wear debris particles are coated in vivo with human proteins, such as albumin; this observation has notably improved the validity of in vitro investigation in this area. His research in the area of joint replacement has twice won awards from the Hip Society. Dr. Maloney is currently the President of the American Academy of Orthopaedic Surgeons and has served on numerous AAOS committees, including the Council on Education. Previously, he was chair of the American Joint Replacement Registry Board of Directors (AJRR), and on the board of directors for the Knee Society, the Hip Society, the Western Orthopaedic Association, and the American Association of Hip and Knee Surgeons (AAHKS). Dr. Maloney is a past president of the Hip Society. He has been a Visiting Professor to numerous universities and institutions throughout the United States and Asia.
Douglass M. and Nola Leishman Professor of Cardiovascular Diseases, and Professor of Pediatrics (Cardiology) and of Bioengineering
Current Research and Scholarly InterestsThe Cardiovascular Biomechanics Computation Lab at Stanford develops novel computational methods for the study of cardiovascular disease progression, surgical methods, and medical devices. We have a particular interest in pediatric cardiology, and use virtual surgery to design novel surgical concepts for children born with heart defects.
Michaëlle Ntala Mayalu
Assistant Professor of Mechanical Engineering
BioDr. Michaëlle N. Mayalu is an Assistant Professor of Mechanical Engineering. She received her Ph.D., M.S., and B.S., degrees in Mechanical Engineering at the Massachusetts Institute of Technology. She was a postdoctoral scholar at the California Institute of Technology in the Computing and Mathematical Sciences Department. She was a 2017 California Alliance Postdoctoral Fellowship Program recipient and a 2019 Burroughs Wellcome Fund Postdoctoral Enrichment Program award recipient.
Dr. Michaëlle N. Mayalu's area of expertise is in mathematical modeling and control theory of synthetic biological and biomedical systems. She is interested in the development of control theoretic tools for understanding, controlling, and predicting biological function at the molecular, cellular, and organismal levels to optimize therapeutic intervention.
She is the director of the Mayalu Lab whose research objective is to investigate how to optimize biomedical therapeutic designs using theoretical and computational approaches coupled with experiments. Initial project concepts include: i) theoretical and experimental design of bacterial "microrobots" for preemptive and targeted therapeutic intervention, ii) system-level multi-scale modeling of gut associated skin disorders for virtual evaluation and optimization of therapy, iii) theoretical and experimental design of "microrobotic" swarms of engineered bacteria with sophisticated centralized and decentralized control schemes to explore possible mechanisms of pattern formation. The experimental projects in the Mayalu Lab utilize established techniques borrowed from the field of synthetic biology to develop synthetic genetic circuits in E. coli to make bacterial "microrobots". Ultimately the Mayalu Lab aims to develop accurate and efficient modeling frameworks that incorporate computation, dynamical systems, and control theory that will become more widespread and impactful in the design of electro-mechanical and biological therapeutic machines.
Jennifer A McNab
Associate Professor (Research) of Radiology (Radiological Sciences Laboratory)
Current Research and Scholarly InterestsMy research is focused on developing magnetic resonance imaging (MRI) methods that probe brain tissue microstructure. This requires new MRI contrast mechanisms, strategic encoding and reconstruction schemes, physiological monitoring, brain tissue modeling and validation. Applications of these methods include neuronavigation, neurosurgical planning and the development of improved biomarkers for brain development, degeneration, disease and injury.
Emmanuel Mignot, MD, PhD
Craig Reynolds Professor of Sleep Medicine and Professor, by courtesy, of Genetics and of Neurology
Current Research and Scholarly InterestsThe research focus of the laboratory is the study of sleep and sleep disorders such as narcolepsy and Kleine Levin syndrome. We also study the neurobiological and genetic basis of the EEG and develop new tools to study sleep using nocturnal polysomnography. Approaches mostly involve human genetic studies (GWAS, sequencing), EEG signal analysis, and immunology (as narcolepsy is an autoimmune disease of the brain).
Stephen B. Montgomery
Associate Professor of Pathology, of Genetics, of Biomedical Data Science and, by courtesy, of Computer Science
Current Research and Scholarly InterestsWe focus on understanding the effects of genome variation on cellular phenotypes and cellular modeling of disease through genomic approaches such as next generation RNA sequencing in combination with developing and utilizing state-of-the-art bioinformatics and statistical genetics approaches. See our website at http://montgomerylab.stanford.edu/
Julie Muccini, MS, OTR/L
Research Engineer, Rad/Musculoskeletal Imaging
BioJulie Muccini is an occupational therapist specializing in working with individuals with neurological diagnoses. She is registered and licensed in California and is a member of the American Occupational Therapy Association (AOTA) and the Occupational Therapy Association of California (OTAC). She is actively involved in research on recovery post-stroke. She works in the Human Performance Lab with an interdisciplinary team integrating biomechanics, biomedical engineering, physiology, psychology, and rehabilitation. Ms. Muccini received her bachelor's of science from the University of Massachusetts at Amherst in Industrial Engineering and Operations Research and her master's of science from Boston University in Occupational Therapy. She started working at the hospital at Stanford in 1997 and transitioned to the Outpatient Neuro Rehab Clinic at the Stanford Neurosciences Health Center in 2014. In March 2021, Julie moved over to the Stanford School of Medicine to work in the Human Performance Lab at the Arrillaga Center for Sports and Recreation, ACSR.
Jonathan N. Myers
Clinical Professor (Affiliated), Medicine - Med/Cardiovascular Medicine
BioDr. Myers is a Health Research Scientist at the Palo Alto VA Health Care System; a Clinical Professor at Stanford University (Affiliated), and a Senior Research Career Scientist Award recipient through the VA Rehabilitation Research and Development Program. His research has focused on primary and secondary prevention, and the clinical applications of exercise testing and rehabilitation in patients with cardiovascular disease and other chronic conditions. He has a lengthy history of studying the epidemiology of cardiopulmonary exercise test responses, physical activity patterns, and other lifestyle factors and their relation to health outcomes. He manages the Veterans Exercise Testing Study (VETS), an ongoing, prospective evaluation of Veteran subjects referred for exercise testing for clinical reasons, designed to address exercise test, clinical, and lifestyle factors and their association with health outcomes.
He earned his bachelor’s degree from the University of California, Santa Barbara, his master's degree from San Diego State University, and his doctorate from the University of Southern California. He has been a board member for many organizations including the American Heart Association (AHA), the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR), and the American College of Sports Medicine (ACSM), and serves on the editorial board for 9 journals. He is a recipient of the Michael Pollock Established Investigator Award through the AACVPR, a recipient of the Steven N Blair Award for excellence in physical activity research from the AHA Council on Epidemiology and Prevention and is the 2022 recipient of the American College of Sports Medicine Citation Award. He is a fellow of the AACVPR, ACSM, American College of Cardiology, and the AHA, and has authored and co-authored guidelines on exercise testing and rehabilitation for each of these organizations, including the 2021 editions of the ACSM and AACVPR guidelines.
Hae Young Noh
Associate Professor of Civil and Environmental Engineering
BioHae Young Noh is an associate professor in the Department of Civil and Environmental Engineering. Her research introduced the new concept of “structures as sensors” to enable physical structures (e.g., buildings and vehicle frames) to be user- and environment-aware. In particular, these structures indirectly sense humans and surrounding environments through their structural responses (i.e., vibrations) by inferring the desired information (e.g., human behaviors, environmental conditions, heating and cooling system performance), instead of directly measuring the sensing targets with additional dedicated sensors (e.g., cameras, motion sensors). This concept brought a paradigm shift in how we view these structures and how the structures interact with us.
Traditionally, structures that we inhabit (such as buildings or vehicles) are considered as passive and unchanging objects that we need to monitor and control, utilizing a dense set of sensors to collect information. This has often been complicated by “noise” caused by the occupants and environments. For example, building vibrations induced by indoor and outdoor environmental and operational conditions (e.g., people walking around, traffic outside, heating system running, etc.), have been often seen as noise that needs to be removed in traditional building science and structural engineering; however, they are a rich source of information about structure, users, environment, and resources. Similarly, in vehicle engineering, researchers and engineers have been investigating control and dynamics to reduce vehicle vibration for safety and comfort. However, vibrations measured inside vehicles contain information about transportation infrastructure, vehicle itself, and driver.
Noh's work utilizes this “noise” to empower the structures with the ability to perceive and understand the information about users and surroundings using their own responses, and actively adopt and/or interact to enhance their sustainability and the occupants’ quality of life. Since she utilizes the structure itself as a sensing medium, information collection involves a simpler set of hardware that can be easily maintained throughout the structural lifetime. However, the analysis of data to separate the desired information becomes more challenging. This challenge is addressed through high-rate dynamic sensing and multi-source inferencing. Ultimately, her work aims to allow structural systems to become general sensing platforms that are easier and more practical to deploy and maintain in a long-term.
At Stanford University, Noh received her PhD and MS degrees in the CEE department and her second MS degree in Electrical Engineering. Noh earned her BS in Mechanical and Aerospace Engineering at Cornell University.
Clinical Professor, Psychiatry and Behavioral Sciences
BioDouglas L. Noordsy, MD, is Clinical Professor and Director of Lifestyle Psychiatry, and psychiatrist on the INSPIRE Early Psychosis Clinic in the Department of Psychiatry & Behavioral Sciences at Stanford University School of Medicine. Dr. Noordsy was previously Professor of Psychiatry, Director of Psychosis Services and Investigator in the Psychopharmacology Research Group at the Geisel School of Medicine at Dartmouth. His research interests include medication and lifestyle interventions for individuals with psychotic disorders; methods to facilitate recovery and promote achievement of optimal outcomes for people with schizophrenia and bipolar disorder; and methods to prevent progression of early psychotic disorders. He is particularly interested in the role of physical exercise for prevention of progression of early psychosis and for potentiating learning in CBTp and supported employment and education. Dr. Noordsy is a member of the Schizophrenia International Research Society, the International Early Psychosis Association, and is a fellow of the American Psychiatric Association. He is a member of the editorial boards for Community Mental Health Journal, Clinical Schizophrenia & Related Psychosis, and Schizophrenia Bulletin. Dr. Noordsy was recognized with the Exemplary Psychiatrist Award from the National Alliance on Mental Illness in 2001, and the Excellence in Leadership Award from the Department of Psychiatry & Behavioral Sciences at Stanford in 2018.
Professor (Research) of Psychology
Current Research and Scholarly InterestsVision, development, functional imaging, systems analysis
Assistant Professor of Bioengineering and of Neurosurgery and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsOur group explores neuroengineering and its application to both basic and clinical neuroscience. Our goal is to develop brain-machine interfaces as a platform technology for a variety of brain-related medical conditions including stroke and epilepsy.
Associate Professor of Epidemiology and Population Health
Current Research and Scholarly InterestsMultilevel - from cells to society - epidemiologic study of healthy aging
Richard W. Weiland Professor in the School of Engineering and Professor, by courtesy, of Computer Science
Current Research and Scholarly InterestsMy research focuses on developing the principles and tools needed to realize advanced robotic and human-machine systems capable of physical interaction. Application areas include surgery, simulation and training, rehabilitation, prosthetics, neuromechanics, exploration of hazardous and remote environments (e.g. space), design, and education.
Instructor, Medicine - Stanford Prevention Research Center
BioMarily Oppezzo is a behavioral and learning scientist. She completed her doctorate in Educational Psychology at Stanford in 2013. She also is a registered dietitian and has her master's of nutritional science. She completed her dietetic internship at the Palo Alto Veterans Hospital, and currently consults as a sports dietitian for Stanford's Runsafe program. Her research interests leverage her interdisciplinary training, with a focus on how to get people to change to improve their health and well-being. Specifically, these areas include: using social media to motivate physical activity changes in those with or at risk for heart disease; culturally tailoring nutrition and physical activity recommendations and education materials for an Alaskan native population; how walking can be used to improve people's cognitive and creative thinking; and applying learning theories to medical education topics.
Sergiu P. Pasca
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences and Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program
Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
To address this, we are developing bottom-up approaches to generate and assemble, from multi-cellular components, human neural circuits in vitro and in vivo.
We introduced the use of instructive signals for deriving from human pluripotent stem cells self-organizing 3D cellular structures named brain region-specific spheroids/organoids. We demonstrated that these cultures, such as the ones resembling the cerebral cortex, can be reliably derived across many lines and experiments, contain synaptically connected neurons and non-reactive astrocytes, and can be used to gain mechanistic insights into genetic and environmental brain disorders. Moreover, when maintained as long-term cultures, they recapitulate an intrinsic program of maturation that progresses towards postnatal stages.
We also pioneered a modular system to integrate 3D brain region-specific organoids and study human neuronal migration and neural circuit formation in functional preparations that we named assembloids. We have actively applied these models in combination with studies in long-term ex vivo brain preparations to acquire a deeper understanding of human physiology, evolution and disease mechanisms.
We have carved a unique research program that combines rigorous in vivo and in vitro neuroscience, stem cell and molecular biology approaches to construct and deconstruct previously inaccessible stages of human brain development and function in health and disease.
We believe science is a community effort, and accordingly, we have been advancing the field by broadly and openly sharing our technologies with numerous laboratories around the world and organizing the primary research conference and the training courses in the area of cellular models of the human brain.
Albert Ray Lang Professor of Psychology
Current Research and Scholarly InterestsOur lab uses the tools of cognitive neuroscience to understand how decision making, executive control, and learning and memory are implemented in the human brain. We also develop neuroinformatics tools and resources to help researchers make better sense of data.
Clinical Professor, Psychiatry and Behavioral Sciences
BioDr. Lisa Post, Ph.D. is a licensed clinical psychologist specializing in the treatment of anxiety, depression and adjustment disorders in adults. She has been a practicing clinician at Stanford Hospital and Clinics since 1993. Since 2000, she has been Director of a clinical program for Stanford Varsity Athletes and for nine years has been the Team Clinician for the San Francisco 49ers. Her primary interest are in the treatment of high performing individuals and in stress management.
Carla Pugh, MD, PhD
Thomas Krummel Professor
Current Research and Scholarly InterestsThe Technology Enabled Clinical Improvement (T.E.C.I.) Center is a multidisciplinary team of researchers dedicated to the design and implementation of advanced engineering technologies that facilitate data acquisition relating to clinical performance.